Project name: d8c4f6651e794b9

Chain sequence(s)	A: SKGEELFTGKVPILVEELDGDVNGHKFSVSSSGEGEGDATKGKLTLKFICTTGKLPVPWPTLVTTLVQCFSRYPDHMKRHDFFKSAMPEGYVQERTISFKDDGNYKTRRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSSHHNVYITADKQKNGIKANFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLKEFFVTAAGIT
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.4535
• Maximal score value: 1.2881
• Average score: -0.4405
• Total score value: -99.5641

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	S	A	-0.5254
3	K	A	-1.7391
4	G	A	0.0000
5	E	A	-0.8946
6	E	A	-1.8050
7	L	A	0.3026
8	F	A	0.0000
9	T	A	-0.1116
10	G	A	-0.5453
11	K	A	-1.7405
12	V	A	0.0000
13	P	A	-0.1928
14	I	A	0.0000
15	L	A	0.0533
16	V	A	0.0000
17	E	A	-0.9784
18	L	A	0.0000
19	D	A	-1.9849
20	G	A	0.0000
21	D	A	-1.1521
22	V	A	0.0000
23	N	A	-0.4855
24	G	A	-0.5957
25	H	A	-1.0663
26	K	A	-1.9310
27	F	A	0.0000
28	S	A	-0.2367
29	V	A	0.0000
30	S	A	-0.1487
31	G	A	0.0000
32	E	A	-1.8135
33	G	A	-0.6230
34	E	A	-0.8046
35	G	A	0.0000
36	D	A	0.0000
37	A	A	0.0000
38	T	A	-0.3567
39	K	A	-1.7084
40	G	A	0.0000
41	K	A	-0.4751
42	L	A	0.0000
43	T	A	-0.1381
44	L	A	0.0000
45	K	A	-0.4653
46	F	A	0.0000
47	I	A	0.2838
48	C	A	0.0000
49	T	A	-0.0813
50	T	A	-0.1638
51	G	A	-0.7713
52	K	A	-1.7822
53	L	A	0.0000
54	P	A	-0.0450
55	V	A	0.0000
56	P	A	0.0000
57	W	A	0.0000
58	P	A	0.0000
59	T	A	0.0000
60	L	A	0.0000
61	V	A	0.0000
62	T	A	-0.0123
63	T	A	0.0000
64	L	A	0.0000
68	V	A	0.1558
69	Q	A	-0.1150
70	C	A	0.0000
71	F	A	0.0000
72	S	A	0.0000
73	R	A	-0.9753
74	Y	A	0.0000
75	P	A	-0.3634
76	D	A	-1.9573
77	H	A	-1.2042
78	M	A	0.0000
79	K	A	-1.0868
80	R	A	-2.0094
81	H	A	-0.4910
82	D	A	0.0000
83	F	A	0.0000
84	F	A	0.0000
85	K	A	0.0000
86	S	A	-0.0249
87	A	A	0.0000
88	M	A	0.0000
89	P	A	-0.3559
90	E	A	-1.5158
91	G	A	0.0000
92	Y	A	0.0000
93	V	A	0.0445
94	Q	A	0.0000
95	E	A	-0.6183
96	R	A	0.0000
97	T	A	-0.1947
98	I	A	0.0000
99	S	A	-0.1217
100	F	A	0.0000
101	K	A	-1.5459
102	D	A	-2.0724
103	D	A	-0.6543
104	G	A	0.0000
105	N	A	-0.2417
106	Y	A	0.0000
107	K	A	-1.4183
108	T	A	0.0000
109	R	A	-1.8932
110	A	A	0.0000
111	E	A	-1.2192
112	V	A	0.0000
113	K	A	-0.4469
114	F	A	-0.0221
115	E	A	-0.7719
116	G	A	-0.9340
117	D	A	-1.8775
118	T	A	-0.3481
119	L	A	0.0000
120	V	A	0.0000
121	N	A	0.0000
122	R	A	-0.8669
123	I	A	0.0000
124	E	A	-2.0074
125	L	A	0.0000
126	K	A	-1.6008
127	G	A	0.0000
128	I	A	0.5083
129	D	A	-1.6196
130	F	A	0.0000
131	K	A	-1.9894
132	E	A	-2.4535
133	D	A	-2.1452
134	G	A	-0.5850
135	N	A	-0.3144
136	I	A	0.0000
137	L	A	0.2143
138	G	A	-0.4360
139	H	A	-0.6932
140	K	A	-0.4975
141	L	A	-0.0760
142	E	A	-0.7392
143	Y	A	0.2306
144	N	A	-0.3884
145	Y	A	-0.0114
146	N	A	-0.4207
147	S	A	-0.4598
148	H	A	-0.3763
149	N	A	-1.3015
150	V	A	0.0000
151	Y	A	1.2881
152	I	A	0.0000
153	T	A	-0.1452
154	A	A	-0.0429
155	D	A	-0.5727
156	K	A	-1.9685
157	Q	A	-1.8140
158	K	A	-2.1420
159	N	A	-1.5780
160	G	A	0.0000
161	I	A	0.0000
162	K	A	-0.7861
163	A	A	0.0000
164	N	A	-1.1144
165	F	A	0.0000
166	K	A	-1.3934
167	I	A	0.0000
168	R	A	-1.4662
169	H	A	0.0000
170	N	A	-0.2042
171	I	A	0.0000
172	E	A	-2.1436
173	D	A	-2.2035
174	G	A	-0.8170
175	S	A	-0.0754
176	V	A	0.7305
177	Q	A	0.0000
178	L	A	0.1217
179	A	A	0.0000
180	D	A	-0.4396
181	H	A	0.0000
182	Y	A	1.1618
183	Q	A	0.0000
184	Q	A	-1.0276
185	N	A	0.0000
186	T	A	-0.0419
187	P	A	0.1295
188	I	A	0.9155
189	G	A	-0.2883
190	D	A	-1.8967
191	G	A	-0.8312
192	P	A	-0.2823
193	V	A	0.3000
194	L	A	0.4362
195	L	A	0.8785
196	P	A	0.0000
197	D	A	-2.0254
198	N	A	-1.6063
199	H	A	0.0000
200	Y	A	0.4459
201	L	A	0.0000
202	S	A	-0.2417
203	T	A	-0.2432
204	Q	A	-1.2312
205	S	A	-0.2634
206	A	A	0.0639
207	L	A	0.1665
208	S	A	-0.3057
209	K	A	-1.4172
210	D	A	-0.7514
211	P	A	-0.5733
212	N	A	-1.3592
213	E	A	-0.7645
214	K	A	-2.0592
215	R	A	-2.0780
216	D	A	-0.5741
217	H	A	0.0000
218	M	A	0.0000
219	V	A	0.1343
220	L	A	0.0000
221	K	A	-1.0630
222	E	A	-0.1909
223	F	A	1.0673
224	V	A	0.0000
225	T	A	-0.1455
226	A	A	0.0000
227	A	A	-0.0737
228	G	A	-0.3943
229	I	A	0.2765
230	T	A	-0.0020