Project name: Check 3

Chain sequence(s)	A: NTTGGRFVDKDNRKYYVKDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKWYYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYEDGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKMLTDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSGAMVTGWYQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYSVNYNGEWVQ
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8019
• Maximal score value: 0.8593
• Average score: -0.7323
• Total score value: -227.7304

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	N	A	-2.4627
2	T	A	0.0000
3	T	A	-1.5835
4	G	A	-1.3954
5	G	A	-2.1266
6	R	A	-2.1876
7	F	A	-0.9509
8	V	A	-1.3827
9	D	A	-3.1883
10	K	A	-3.8019
11	D	A	-3.7219
12	N	A	-3.4656
13	R	A	-2.7866
14	K	A	-2.0059
15	Y	A	-0.7779
16	Y	A	0.0000
17	V	A	-1.8667
18	K	A	-2.7043
19	D	A	-3.3588
20	D	A	-3.3952
21	H	A	-2.7821
22	K	A	-1.8458
23	A	A	0.0000
24	I	A	0.0000
25	Y	A	0.0000
26	W	A	0.0000
27	H	A	0.0000
28	K	A	-2.5930
29	I	A	0.0000
30	D	A	-2.8611
31	G	A	-2.3330
32	K	A	-2.5192
33	T	A	0.0000
34	Y	A	0.0000
35	Y	A	0.0000
36	F	A	0.0000
37	G	A	-0.4906
38	D	A	-1.0760
39	I	A	0.6839
40	G	A	0.0000
41	E	A	-0.7181
42	M	A	0.0000
43	V	A	0.0000
44	V	A	0.0000
45	G	A	0.0000
46	W	A	0.0000
47	Q	A	0.0000
48	Y	A	-0.2333
49	L	A	0.0000
50	E	A	-0.6234
51	I	A	-0.2792
52	P	A	-0.4404
53	G	A	-0.7525
54	T	A	-0.0423
55	G	A	-0.4526
56	Y	A	0.1049
57	R	A	-0.5763
58	D	A	-1.0311
59	N	A	-1.8208
60	L	A	-1.3015
61	F	A	0.0000
62	D	A	-2.0097
63	N	A	-2.5234
64	Q	A	-1.9437
65	P	A	-1.1921
66	V	A	-0.9317
67	N	A	-1.5872
68	E	A	-1.8711
69	I	A	-0.4155
70	G	A	-0.2695
71	L	A	-0.0303
72	Q	A	-0.3982
73	E	A	-1.1367
74	K	A	-0.7059
75	W	A	0.0000
76	Y	A	0.0000
77	Y	A	-0.0383
78	F	A	0.0000
79	G	A	-1.1714
80	Q	A	-2.0423
81	D	A	-2.3550
82	G	A	0.0000
83	A	A	-1.3906
84	L	A	0.0000
85	L	A	-0.4734
86	E	A	-1.8313
87	Q	A	-1.9520
88	T	A	-2.4548
89	D	A	-2.9486
90	K	A	-1.9341
91	Q	A	-0.7562
92	V	A	0.4778
93	L	A	0.0000
94	E	A	0.0000
95	A	A	0.0000
96	K	A	0.0000
97	T	A	-0.5300
98	S	A	-1.2179
99	E	A	-1.8869
100	N	A	0.0000
101	T	A	-0.7761
102	G	A	-0.8156
103	K	A	-1.0674
104	V	A	-0.7877
105	Y	A	-1.3050
106	G	A	-2.2135
107	E	A	-1.5694
108	Q	A	-1.4381
109	Y	A	0.0000
110	P	A	-0.1135
111	L	A	0.6034
112	S	A	-0.6317
113	A	A	-0.8202
114	E	A	-2.2752
115	K	A	-2.2738
116	R	A	-1.3488
117	T	A	-0.2708
118	Y	A	0.0000
119	Y	A	-1.0111
120	F	A	0.0000
121	D	A	-2.2457
122	N	A	-2.6074
123	N	A	-2.1826
124	Y	A	-1.6562
125	A	A	0.0000
126	V	A	0.0000
127	K	A	-1.3650
128	T	A	-0.3469
129	G	A	0.0000
130	W	A	0.5728
131	I	A	0.0000
132	Y	A	0.6924
133	E	A	-0.9349
134	D	A	-2.0422
135	G	A	-1.3897
136	N	A	-0.7839
137	W	A	0.3793
138	Y	A	0.3655
139	Y	A	0.0000
140	L	A	0.0000
141	N	A	-0.4576
142	K	A	-0.6093
143	L	A	0.0245
144	G	A	0.0000
145	N	A	-0.6299
146	F	A	0.3979
147	G	A	-1.1814
148	D	A	-2.4694
149	D	A	-2.3658
150	S	A	-1.2465
151	Y	A	-0.0578
152	N	A	-0.4786
153	P	A	-0.3459
154	L	A	-0.2104
155	P	A	-0.4246
156	I	A	0.0000
157	G	A	0.0000
158	E	A	-0.3286
159	V	A	-0.0335
160	A	A	0.0000
161	K	A	-1.6837
162	G	A	-0.8422
163	W	A	-0.0150
164	T	A	-0.1878
165	Q	A	-0.1763
166	D	A	-0.2367
167	F	A	-1.0367
168	H	A	-1.5136
169	V	A	-0.5257
170	T	A	0.0895
171	I	A	0.7248
172	D	A	-1.1572
173	I	A	-1.3405
174	D	A	-2.4114
175	R	A	-2.9750
176	S	A	-2.0118
177	K	A	-2.1961
178	P	A	-1.3981
179	A	A	-0.8852
180	P	A	-0.1172
181	W	A	0.2569
182	Y	A	0.0000
183	Y	A	-0.0432
184	L	A	0.0000
185	D	A	-0.8883
186	A	A	-0.7592
187	S	A	-0.6994
188	G	A	0.0000
189	K	A	-0.7593
190	M	A	-0.1212
191	L	A	-0.0474
192	T	A	-0.2266
193	D	A	-0.4915
194	W	A	-0.4048
195	Q	A	-1.2963
196	K	A	-2.3704
197	V	A	0.0000
198	N	A	-2.1678
199	G	A	-1.9990
200	K	A	-2.0591
201	W	A	-1.1215
202	Y	A	0.0000
203	Y	A	-0.2318
204	F	A	0.0000
205	G	A	-0.4385
206	S	A	-0.4269
207	S	A	-0.3074
208	G	A	0.0000
209	S	A	-0.0280
210	M	A	0.0801
211	A	A	-0.5736
212	T	A	-1.1690
213	G	A	0.0000
214	W	A	0.2546
215	K	A	-0.1148
216	Y	A	0.3147
217	V	A	0.0000
218	R	A	-2.1569
219	G	A	-1.5612
220	K	A	-1.6110
221	W	A	-0.2259
222	Y	A	-0.0292
223	Y	A	0.0000
224	L	A	0.0000
225	D	A	-1.8040
226	N	A	-2.3238
227	K	A	-2.8900
228	N	A	-2.2559
229	G	A	0.0000
230	D	A	0.0000
231	M	A	-0.5726
232	K	A	-0.6737
233	T	A	-0.7541
234	G	A	-0.5427
235	W	A	0.2680
236	Q	A	0.2394
237	Y	A	0.5970
238	L	A	-0.0957
239	G	A	-1.0166
240	N	A	-1.5803
241	K	A	-1.2588
242	W	A	0.1035
243	Y	A	0.0000
244	Y	A	-0.0384
245	L	A	0.0000
246	R	A	-1.9702
247	S	A	-1.2594
248	S	A	-0.8983
249	G	A	0.0000
250	A	A	-0.8447
251	M	A	-0.4730
252	V	A	0.0000
253	T	A	-0.2644
254	G	A	0.0681
255	W	A	0.2011
256	Y	A	-0.1705
257	Q	A	-0.9696
258	D	A	-1.0267
259	G	A	-0.3963
260	L	A	0.8593
261	T	A	0.2603
262	W	A	0.1706
263	Y	A	0.0501
264	Y	A	0.1312
265	L	A	0.0000
266	N	A	-0.9206
267	A	A	-0.6289
268	G	A	-1.1981
269	N	A	-1.5309
270	G	A	0.0000
271	D	A	0.0000
272	M	A	-0.2604
273	K	A	-0.5107
274	T	A	-0.0524
275	G	A	0.1854
276	W	A	0.4054
277	F	A	0.0000
278	Q	A	-1.6494
279	V	A	-1.5083
280	N	A	-2.0546
281	G	A	-1.9652
282	K	A	-2.0117
283	W	A	-0.6365
284	Y	A	0.0000
285	Y	A	0.6734
286	A	A	0.0000
287	Y	A	0.6084
288	S	A	-0.0365
289	S	A	-0.0568
290	G	A	0.0000
291	A	A	0.3195
292	L	A	0.0000
293	A	A	0.0000
294	V	A	0.4750
295	N	A	-0.5391
296	T	A	-0.3766
297	T	A	-0.4463
298	V	A	0.0000
299	D	A	-1.8037
300	G	A	-1.0048
301	Y	A	0.0307
302	S	A	-0.1616
303	V	A	0.0000
304	N	A	-0.0412
305	Y	A	0.7070
306	N	A	-0.1250
307	G	A	0.0000
308	E	A	-0.4587
309	W	A	0.2838
310	V	A	0.3485
311	Q	A	-0.5977