Project name: DspB

Chain sequence(s)	A: TKQTGLMLDIARHFYSPEVIKSFIDTISLSGGNFLHLHFSDHENYAIESHLLNQRAENAVQGKDGIYINPYTGKPFLSYRQLDDIKAYAKAKGIELIPELDSPNHMTAIFKLVQKDRGVKYLQGLKSRQVDDEIDITNADSITFMQSLMSEVIDIFGDTSQHFHIGGDEFGYSVESNHEFITYANKLSYFLEKKGLKTRMWNDGLIKNTFEQINPNIEITYWSYDGDTQDKNEAAERRDMRVSLPELLAKGFTVLNYNSYYLYIVPKASPTFSQDAAFAAKDVIKNWDLGVWDGRNTKNRVQNTHEIAGAALSIWGEDAKALKDETIQKNTKSLLEAVIHKTNG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.9339
• Maximal score value: 0.9658
• Average score: -0.8497
• Total score value: -292.308

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
16	T	A	-0.6093
17	K	A	-1.0365
18	Q	A	-0.6567
19	T	A	0.0000
20	G	A	0.0000
21	L	A	0.0000
22	M	A	0.0000
23	L	A	0.0000
24	D	A	0.0000
25	I	A	0.0000
26	A	A	0.0000
27	R	A	-1.6414
28	H	A	-1.4606
29	F	A	-0.4059
30	Y	A	0.0000
31	S	A	-1.1674
32	P	A	0.0000
33	E	A	-2.1659
34	V	A	0.0000
35	I	A	0.0000
36	K	A	-1.2489
37	S	A	-1.2514
38	F	A	0.0000
39	I	A	0.0000
40	D	A	-0.2899
41	T	A	0.0000
42	I	A	0.0000
43	S	A	-0.0997
44	L	A	0.9658
45	S	A	0.0000
46	G	A	-0.6072
47	G	A	-0.7334
48	N	A	-0.7034
49	F	A	0.0000
50	L	A	0.0000
51	H	A	0.0000
52	L	A	0.0000
53	H	A	0.0000
54	F	A	0.0000
55	S	A	0.0000
56	D	A	0.0000
57	H	A	-1.5122
58	E	A	-2.4246
59	N	A	0.0000
60	Y	A	0.0000
61	A	A	0.0000
62	I	A	0.0000
63	E	A	0.0000
64	S	A	0.0000
65	H	A	-1.4561
66	L	A	-0.9557
67	L	A	0.0000
68	N	A	-2.3292
69	Q	A	0.0000
70	R	A	-1.8277
71	A	A	-1.5494
72	E	A	-2.3885
73	N	A	-2.0265
74	A	A	-0.5988
75	V	A	0.5752
76	Q	A	-1.2157
77	G	A	-1.6372
78	K	A	-2.7468
79	D	A	-2.8778
80	G	A	-1.5800
81	I	A	-0.8456
82	Y	A	0.0000
83	I	A	0.2737
84	N	A	0.0000
85	P	A	0.0988
86	Y	A	0.0040
87	T	A	-0.6486
88	G	A	-0.3305
89	K	A	-1.0250
90	P	A	-0.1984
91	F	A	0.0000
92	L	A	0.0000
93	S	A	0.0000
94	Y	A	-1.3538
95	R	A	-2.7159
96	Q	A	-2.1360
97	L	A	0.0000
98	D	A	-2.8681
99	D	A	-2.6916
100	I	A	0.0000
101	K	A	-2.1596
102	A	A	-1.4289
103	Y	A	-1.1331
104	A	A	0.0000
105	K	A	-2.3156
106	A	A	-1.1990
107	K	A	-1.4109
108	G	A	-1.5602
109	I	A	0.0000
110	E	A	-1.4608
111	L	A	0.0000
112	I	A	0.0000
113	P	A	0.0000
114	E	A	0.0000
115	L	A	0.0000
116	D	A	0.0000
117	S	A	0.0000
118	P	A	0.0000
119	N	A	-0.6245
120	H	A	-0.7453
121	M	A	0.0000
122	T	A	-1.2780
123	A	A	-1.1853
124	I	A	0.0000
125	F	A	0.0000
126	K	A	-1.9451
127	L	A	0.0000
128	V	A	0.0000
129	Q	A	-2.1393
130	K	A	-2.8187
131	D	A	-2.6808
132	R	A	-2.1114
133	G	A	-1.5107
134	V	A	-0.6048
135	K	A	-1.3404
136	Y	A	-0.6045
137	L	A	0.0000
138	Q	A	-1.5064
139	G	A	-1.1413
140	L	A	0.0000
141	K	A	0.0000
142	S	A	-2.1200
143	R	A	-3.0135
144	Q	A	-2.5009
145	V	A	-1.8348
146	D	A	-2.8871
147	D	A	-2.0581
148	E	A	0.0000
149	I	A	0.0000
150	D	A	-1.5101
151	I	A	0.0000
152	T	A	-0.7006
153	N	A	-0.8921
154	A	A	-0.9292
155	D	A	-1.8791
156	S	A	0.0000
157	I	A	-0.7953
158	T	A	-0.7301
159	F	A	0.0000
160	M	A	0.0000
161	Q	A	-0.5507
162	S	A	-0.1765
163	L	A	0.0000
164	M	A	0.0000
165	S	A	-0.6971
166	E	A	-0.9907
167	V	A	0.0000
168	I	A	-1.2831
169	D	A	-2.0925
170	I	A	0.0000
171	F	A	0.0000
172	G	A	-2.0668
173	D	A	-2.6688
174	T	A	0.0000
175	S	A	0.0000
176	Q	A	-2.1762
177	H	A	-1.4156
178	F	A	0.0000
179	H	A	0.0000
180	I	A	0.0000
181	G	A	0.0000
182	G	A	0.0000
183	D	A	0.0000
184	E	A	-0.2786
185	F	A	0.0651
186	G	A	-0.1962
187	Y	A	0.7204
188	S	A	0.0089
189	V	A	-0.5680
190	E	A	-1.9046
191	S	A	-1.3851
192	N	A	-1.6276
193	H	A	-2.1735
194	E	A	-1.8143
195	F	A	0.0000
196	I	A	0.0000
197	T	A	-1.2722
198	Y	A	0.0000
199	A	A	0.0000
200	N	A	-0.9898
201	K	A	-1.2105
202	L	A	0.0000
203	S	A	0.0000
204	Y	A	-0.5429
205	F	A	-0.9493
206	L	A	0.0000
207	E	A	-2.5090
208	K	A	-2.5168
209	K	A	-2.1894
210	G	A	-2.1303
211	L	A	0.0000
212	K	A	-2.4567
213	T	A	0.0000
214	R	A	0.0000
215	M	A	0.0000
216	W	A	0.0000
217	N	A	0.0000
218	D	A	0.0000
219	G	A	0.0000
220	L	A	0.0000
221	I	A	0.0000
222	K	A	-2.2449
223	N	A	-2.3233
224	T	A	0.0000
225	F	A	0.0000
226	E	A	-3.0934
227	Q	A	-2.4188
228	I	A	0.0000
229	N	A	0.0000
230	P	A	-1.7420
231	N	A	-1.7273
232	I	A	0.0000
233	E	A	0.0000
234	I	A	0.0000
235	T	A	0.0000
236	Y	A	0.0000
237	W	A	0.0000
238	S	A	0.0000
239	Y	A	-0.4071
240	D	A	0.0000
241	G	A	-0.9630
242	D	A	-1.6215
243	T	A	-2.2148
244	Q	A	-2.8333
245	D	A	-3.4923
246	K	A	-3.9339
247	N	A	-3.6527
248	E	A	-3.8295
249	A	A	0.0000
250	A	A	-2.8914
251	E	A	-3.5013
252	R	A	-2.4019
253	R	A	-2.2497
254	D	A	-2.8096
255	M	A	-1.7636
256	R	A	0.0000
257	V	A	0.0000
258	S	A	0.0000
259	L	A	0.0000
260	P	A	-1.1234
261	E	A	-1.3714
262	L	A	0.0000
263	L	A	-1.1669
264	A	A	-1.3276
265	K	A	-2.3710
266	G	A	-1.7559
267	F	A	0.0000
268	T	A	-0.8233
269	V	A	0.0000
270	L	A	0.0000
271	N	A	0.0000
272	Y	A	0.0000
273	N	A	0.0000
274	S	A	0.1830
275	Y	A	0.3737
276	Y	A	0.0000
277	L	A	0.0000
278	Y	A	0.8036
279	I	A	0.6937
280	V	A	-0.0596
281	P	A	0.0000
282	K	A	-2.5612
283	A	A	-1.6756
284	S	A	-0.8782
285	P	A	-0.8570
286	T	A	-1.2583
287	F	A	0.0000
288	S	A	-1.4015
289	Q	A	-1.3407
290	D	A	-1.7961
291	A	A	0.0000
292	A	A	-0.6900
293	F	A	0.3678
294	A	A	-0.4335
295	A	A	0.0000
296	K	A	-1.6587
297	D	A	-1.4302
298	V	A	0.0000
299	I	A	-0.5242
300	K	A	-2.1694
301	N	A	-1.9624
302	W	A	0.0000
303	D	A	-0.9622
304	L	A	0.0000
305	G	A	0.0000
306	V	A	0.0000
307	W	A	0.0000
308	D	A	0.0000
309	G	A	-0.8675
310	R	A	-2.1763
311	N	A	-2.0871
312	T	A	-2.1754
313	K	A	-2.8409
314	N	A	-2.6359
315	R	A	-2.5280
316	V	A	0.0000
317	Q	A	-2.4799
318	N	A	-2.6268
319	T	A	-2.1100
320	H	A	-2.3337
321	E	A	-2.5212
322	I	A	0.0000
323	A	A	-0.7253
324	G	A	0.0000
325	A	A	0.0000
326	A	A	0.0000
327	L	A	0.0000
328	S	A	0.0000
329	I	A	0.0000
330	W	A	-0.2754
331	G	A	0.0000
332	E	A	-2.5352
333	D	A	-3.0682
334	A	A	0.0000
335	K	A	-2.9439
336	A	A	-1.6913
337	L	A	-1.8893
338	K	A	-2.0837
339	D	A	0.0000
340	E	A	-1.8801
341	T	A	-1.4901
342	I	A	0.0000
343	Q	A	0.0000
344	K	A	-2.3451
345	N	A	-1.8502
346	T	A	0.0000
347	K	A	-1.9550
348	S	A	-1.3422
349	L	A	0.0000
350	L	A	0.0000
351	E	A	-1.1851
352	A	A	0.0000
353	V	A	0.0000
354	I	A	0.0000
355	H	A	-1.3432
356	K	A	-1.2464
357	T	A	0.0000
358	N	A	-1.5914
359	G	A	-1.2987