Project name: d90890f43ce5196

Chain sequence(s)	A: NLKLGFLVKQPEEPWFQTEWKFADKAGKDLGFEVIKIAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKARGYDMKVIAVDDQFVNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAVMAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPEVKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLLPSPDVHGYKSSEMLYNWVAKDVEPPKFTEVTDVVLITRDNFKEELEKKGLGGK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.3237
• Maximal score value: 0.643
• Average score: -0.9315
• Total score value: -284.1002

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	N	A	-1.8700
3	L	A	-1.5925
4	K	A	-2.0044
5	L	A	0.0000
6	G	A	0.0000
7	F	A	0.0000
8	L	A	0.0000
9	V	A	0.0000
10	K	A	-1.1253
11	Q	A	-1.3240
12	P	A	-1.4387
13	E	A	-2.1568
14	E	A	0.0000
15	P	A	-0.9640
16	W	A	0.0000
17	F	A	0.0000
18	Q	A	-1.8697
19	T	A	0.0000
20	E	A	0.0000
21	W	A	-1.3465
22	K	A	-2.2342
23	F	A	-1.3117
24	A	A	0.0000
25	D	A	-2.4555
26	K	A	-2.7117
27	A	A	0.0000
28	G	A	0.0000
29	K	A	-3.3340
30	D	A	-2.8765
31	L	A	-1.6469
32	G	A	-1.9861
33	F	A	0.0000
34	E	A	-2.8512
35	V	A	0.0000
36	I	A	-0.7650
37	K	A	-1.3190
38	I	A	-0.3440
39	A	A	-0.8154
40	V	A	0.0000
41	P	A	-1.6232
42	D	A	-2.5526
43	G	A	-2.4269
44	E	A	-2.9144
45	K	A	-2.6323
46	T	A	0.0000
47	L	A	-1.5863
48	N	A	-2.2585
49	A	A	0.0000
50	I	A	0.0000
51	D	A	-1.3277
52	S	A	-0.7935
53	L	A	0.0000
54	A	A	-1.0303
55	A	A	-0.3089
56	S	A	-0.6815
57	G	A	-1.1399
58	A	A	0.0000
59	K	A	-2.0883
60	G	A	0.0000
61	F	A	0.0000
62	V	A	0.0000
63	I	A	0.0000
64	C	A	0.0000
65	T	A	0.0000
66	P	A	-1.3794
67	D	A	-1.9573
68	P	A	-1.7754
69	K	A	-2.2696
70	L	A	-1.1563
71	G	A	0.0000
72	S	A	-0.4344
73	A	A	-0.4241
74	I	A	0.0000
75	V	A	-0.4307
76	A	A	-0.6946
77	K	A	-1.3527
78	A	A	0.0000
79	R	A	-2.6020
80	G	A	-1.6332
81	Y	A	-1.5032
82	D	A	-2.7292
83	M	A	0.0000
84	K	A	-1.3589
85	V	A	0.0000
86	I	A	0.0000
87	A	A	0.0000
88	V	A	0.0000
89	D	A	0.0000
90	D	A	0.0000
91	Q	A	-0.9877
92	F	A	0.0000
93	V	A	-2.0195
94	N	A	-2.0768
95	A	A	-1.7400
96	K	A	-2.6226
97	G	A	-2.5814
98	K	A	-2.8823
99	P	A	-2.1246
100	M	A	-1.4987
101	D	A	-2.1944
102	T	A	-1.1064
103	V	A	-0.6757
104	P	A	0.0000
105	L	A	0.0000
106	V	A	0.0000
107	M	A	0.0000
108	M	A	0.0000
109	A	A	0.0000
110	A	A	0.0000
111	T	A	-1.2441
112	K	A	-1.8594
113	I	A	0.0000
114	G	A	0.0000
115	E	A	-2.5724
116	R	A	-1.8174
117	Q	A	0.0000
118	G	A	0.0000
119	Q	A	-2.0552
120	E	A	0.0000
121	L	A	0.0000
122	Y	A	-1.6588
123	K	A	-2.6139
124	E	A	0.0000
125	M	A	0.0000
126	Q	A	-2.8262
127	K	A	-3.0552
128	R	A	-2.2690
129	G	A	-1.7268
130	W	A	-1.5729
131	D	A	-1.5849
132	V	A	-0.9363
133	K	A	-2.1573
134	E	A	-2.0967
135	S	A	0.0000
136	A	A	0.0000
137	V	A	0.0000
138	M	A	0.0000
139	A	A	0.0000
140	I	A	0.0000
141	T	A	0.0000
142	A	A	0.0000
143	N	A	-2.1384
144	E	A	-2.6240
145	L	A	-2.0849
146	D	A	-2.0430
147	T	A	0.0000
148	A	A	0.0000
149	R	A	-2.0062
150	R	A	-1.5396
151	R	A	0.0000
152	T	A	0.0000
153	T	A	-1.1716
154	G	A	0.0000
155	S	A	0.0000
156	M	A	-1.6132
157	D	A	-2.6197
158	A	A	-2.0048
159	L	A	0.0000
160	K	A	-2.3168
161	A	A	-1.4057
162	A	A	-1.0081
163	G	A	-1.1114
164	F	A	0.0000
165	P	A	-1.8764
166	E	A	-3.1070
167	K	A	-2.6402
168	Q	A	-1.7469
169	I	A	-1.1541
170	Y	A	-0.7254
171	Q	A	-0.8281
172	V	A	-0.8255
173	P	A	-1.3091
174	T	A	-1.4146
175	K	A	-2.1720
176	S	A	-1.3160
177	N	A	-0.7527
178	D	A	-0.4994
179	I	A	0.1848
180	P	A	-0.5610
181	G	A	0.0000
182	A	A	0.0000
183	F	A	-0.3651
184	D	A	-1.8670
185	A	A	0.0000
186	A	A	0.0000
187	N	A	-0.9763
188	S	A	-0.4413
189	M	A	0.0000
190	L	A	0.0000
191	V	A	0.6430
192	Q	A	-0.7947
193	H	A	-1.0325
194	P	A	-1.3730
195	E	A	-2.5124
196	V	A	0.0000
197	K	A	-2.2356
198	H	A	-1.4709
199	W	A	0.0000
200	L	A	0.0000
201	I	A	0.0000
202	V	A	0.0000
203	G	A	0.0000
204	M	A	0.0000
205	N	A	0.0000
206	D	A	0.0000
207	S	A	-0.0182
208	T	A	0.0000
209	V	A	0.0000
210	L	A	0.0000
211	G	A	0.0000
212	G	A	0.0000
213	V	A	0.0000
214	R	A	-0.9090
215	A	A	0.0000
216	T	A	0.0000
217	E	A	-2.0851
218	G	A	-1.6382
219	Q	A	-1.4500
220	G	A	-1.5351
221	F	A	-1.6548
222	K	A	-2.0674
223	A	A	-1.0889
224	A	A	-0.5867
225	D	A	-0.9990
226	I	A	0.0000
227	I	A	0.0000
228	G	A	0.0000
229	I	A	0.0000
230	G	A	0.0000
231	I	A	0.0000
232	N	A	0.0000
233	G	A	0.0000
234	V	A	0.0000
235	D	A	-0.5739
236	A	A	0.0000
237	V	A	-0.6456
238	S	A	-0.5571
239	E	A	0.0000
240	L	A	0.0000
241	S	A	-1.2725
242	K	A	-1.3739
243	A	A	-1.0434
244	Q	A	-1.5207
245	A	A	-0.7847
246	T	A	-0.8056
247	G	A	0.0000
248	F	A	0.0000
249	Y	A	0.2188
250	G	A	0.0000
251	S	A	0.0000
252	L	A	0.0000
253	L	A	0.0000
254	P	A	0.0000
255	S	A	0.0000
256	P	A	0.0000
257	D	A	-0.4450
258	V	A	0.2406
259	H	A	0.0000
260	G	A	0.0000
261	Y	A	-0.5890
262	K	A	-0.3323
263	S	A	0.0000
264	S	A	0.0000
265	E	A	-0.8247
266	M	A	-0.2984
267	L	A	0.0000
268	Y	A	-0.6305
269	N	A	-0.9290
270	W	A	-1.1799
271	V	A	-1.1073
272	A	A	-1.0229
273	K	A	-2.2514
274	D	A	-2.3139
275	V	A	-0.8867
276	E	A	-2.0993
277	P	A	-1.1180
278	P	A	-0.8561
279	K	A	-1.7041
280	F	A	-0.1203
281	T	A	-0.3420
282	E	A	-0.8670
283	V	A	0.0000
284	T	A	-1.0904
285	D	A	-1.2864
286	V	A	-0.3021
287	V	A	0.2910
288	L	A	0.3264
289	I	A	0.0000
290	T	A	0.0000
291	R	A	-2.0869
292	D	A	-2.8289
293	N	A	-2.4981
294	F	A	0.0000
295	K	A	-4.0538
296	E	A	-4.3237
297	E	A	-3.1671
298	L	A	0.0000
299	E	A	-4.2179
300	K	A	-3.6741
301	K	A	-2.3553
302	G	A	-1.9616
303	L	A	-2.1758
304	G	A	-2.6514
305	G	A	-2.2711
306	K	A	-2.8830