Project name: d91d1b89d706365

Chain sequence(s)	A: RRRWFHPNITGVEAENNLLLTRGVDGSFLARPSKKSNPGDFTLLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESKSKVTHVMIRCQKYDVGGGERFDSLTDLVEHYKKKNPMVETTLGTVLQLKQPLNTTR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.3822
• Maximal score value: 2.1241
• Average score: -1.2268
• Total score value: -260.0915

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
4	R	A	-2.8160
5	R	A	-2.7983
6	W	A	0.0000
7	F	A	0.0000
8	H	A	0.0000
9	P	A	-0.7266
10	N	A	-1.4197
11	I	A	-0.6693
12	T	A	-0.5299
13	G	A	-0.0381
14	V	A	1.0617
15	E	A	-0.3555
16	A	A	0.0000
17	E	A	-0.3689
18	N	A	-1.0119
19	L	A	-0.5420
20	L	A	0.0000
21	L	A	0.1036
22	T	A	-0.3846
23	R	A	-1.1030
24	G	A	-0.1854
25	V	A	0.4516
26	D	A	-1.3689
27	G	A	-1.4999
28	S	A	0.0000
29	F	A	0.0000
30	L	A	0.0000
31	A	A	0.0000
32	R	A	0.0000
33	P	A	-1.1550
34	S	A	-1.6567
35	K	A	-2.2465
36	S	A	-1.8619
37	N	A	-2.2202
38	P	A	-1.5847
39	G	A	-1.3037
40	D	A	0.0000
41	F	A	-0.8827
42	T	A	0.0000
43	L	A	0.0000
44	S	A	0.0000
45	V	A	0.0000
46	R	A	-1.0201
47	R	A	-1.5227
48	N	A	-1.8149
49	G	A	-1.0421
50	A	A	-0.7261
51	V	A	-0.4013
52	T	A	-0.4879
53	H	A	-0.7539
54	I	A	-0.6849
55	K	A	-1.5738
56	I	A	0.0000
57	Q	A	-0.7632
58	N	A	-1.0958
59	T	A	-0.9431
60	G	A	-1.4700
61	D	A	-2.0970
62	Y	A	-1.3337
63	Y	A	-0.9792
64	D	A	0.0000
65	L	A	-0.4123
66	Y	A	0.2635
67	G	A	-0.5532
68	G	A	-1.5890
69	E	A	-2.4871
70	K	A	-2.5852
71	F	A	-1.4384
72	A	A	-0.8295
73	T	A	-0.8761
74	L	A	0.0000
75	A	A	-1.0989
76	E	A	-1.5484
77	L	A	0.0000
78	V	A	0.0000
79	Q	A	-1.7372
80	Y	A	-1.5790
81	Y	A	0.0000
82	M	A	-2.1120
83	E	A	-2.8691
84	H	A	-2.3867
85	H	A	-2.7032
86	G	A	-2.0838
87	Q	A	-2.2219
88	L	A	0.0000
89	K	A	-3.8694
90	E	A	-3.6664
91	K	A	-3.6642
92	N	A	-3.1903
93	G	A	-3.2755
94	D	A	-3.3265
95	V	A	-2.5981
96	I	A	0.0000
97	E	A	-3.1963
98	L	A	0.0000
99	K	A	-2.2310
100	Y	A	-0.3974
101	P	A	-0.6078
102	L	A	0.0000
103	N	A	-1.5116
104	C	A	-1.0531
105	A	A	-1.0561
106	D	A	-1.9727
107	P	A	-1.1047
108	T	A	0.0000
109	S	A	-1.4552
110	E	A	-2.1612
111	R	A	-2.7918
112	W	A	-1.5538
113	F	A	0.0000
114	H	A	0.0000
115	G	A	-1.3963
116	H	A	-1.4597
117	L	A	-1.3032
118	S	A	-1.8774
119	G	A	-1.9642
120	K	A	-2.8788
121	E	A	-2.8328
122	A	A	0.0000
123	E	A	-2.7050
124	K	A	-3.3017
125	L	A	-2.1920
126	L	A	0.0000
127	T	A	-3.2935
128	E	A	-3.5244
129	K	A	-3.0690
130	G	A	-2.8178
131	K	A	-3.7171
132	H	A	-2.7646
133	G	A	0.0000
134	S	A	0.0000
135	F	A	0.0000
136	L	A	0.0000
137	V	A	0.0000
138	R	A	0.0000
139	E	A	-1.6107
140	S	A	0.0000
141	Q	A	-1.9280
142	S	A	-1.3093
143	H	A	-1.6632
144	P	A	-1.4953
145	G	A	-1.4351
146	D	A	0.0000
147	F	A	0.0000
148	V	A	0.0000
149	L	A	0.0000
150	S	A	0.0000
151	V	A	0.0000
152	R	A	0.0000
153	T	A	-1.2967
154	G	A	-2.0374
155	D	A	-3.7665
156	D	A	-4.3822
157	K	A	-4.3311
158	G	A	-3.3481
159	E	A	-3.3749
160	S	A	-2.5512
164	K	A	-2.1569
165	S	A	-1.5689
166	K	A	0.0000
167	V	A	0.0000
168	T	A	-0.5009
169	H	A	-0.3048
170	V	A	0.0509
171	M	A	-0.1063
172	I	A	0.0000
173	R	A	-1.7309
174	C	A	-1.7050
175	Q	A	-1.8441
178	K	A	-3.2417
179	Y	A	-2.5944
180	D	A	0.0000
181	V	A	-0.8254
182	G	A	-1.1368
183	G	A	-1.5697
184	G	A	-1.7810
185	E	A	-2.9524
186	R	A	-3.7087
187	F	A	-2.7673
188	D	A	-2.9384
189	S	A	-2.1205
190	L	A	0.0000
191	T	A	-1.6570
192	D	A	-2.7450
193	L	A	0.0000
194	V	A	0.0000
195	E	A	-3.2540
196	H	A	-2.7155
197	Y	A	-2.2016
198	K	A	-3.2784
199	K	A	-3.3159
200	N	A	-2.0611
201	P	A	-0.8225
202	M	A	0.5628
203	V	A	2.1241
204	E	A	1.1953
205	T	A	0.9634
206	L	A	1.6199
207	G	A	0.9797
208	T	A	1.1039
209	V	A	1.7928
210	L	A	0.0000
211	Q	A	-1.2527
212	L	A	0.0000
213	K	A	-2.4052
214	Q	A	-1.7119
215	P	A	-1.3053
216	L	A	-1.4445
217	N	A	-2.2361
218	T	A	-1.8093
219	T	A	-1.4814
220	R	A	-2.2528