Project name: 3J9T: chain H de veritat

Chain sequence(s)	P: MGATKILMDSTHFNEIRSIIRSRSVAWDALARSEELSEIDASTAKALESILVKKNNGKTLIPLIHLLSTSDNEDCKKSVQNLIAELLSSDKYGDDTVKFFQEDPKQLEQLFDVSLKGDFQTVLISGFNVVSLLVQNGLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIPEYRDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVKITIKEKVSRLCISIILQCCSTRVKQHKKVIKQLLLLGNALPTVQSLSERKYSDEELRQDISNLKEILENEYQELTSFDEYVAELDSKLLCWSPPHVDNGFWSDNIDEFKKDNYKIFRQLIELLQAKVRNGDVNAKQEKIIIQVALNDITHVVELLPESIDVLDKTGGKADIMELLNHSDSRVKYEALKATQAIIGYTFK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.3433
• Maximal score value: 2.3762
• Average score: -0.9339
• Total score value: -430.5456

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	P	-0.3421
2	G	P	0.0000
3	A	P	-0.8123
4	T	P	-0.7578
5	K	P	-2.0559
6	I	P	-0.9629
7	L	P	0.0000
8	M	P	-1.1522
9	D	P	-1.9884
10	S	P	0.0000
11	T	P	-1.1206
12	H	P	0.0000
13	F	P	0.0000
14	N	P	-1.3342
15	E	P	-1.1889
16	I	P	0.0000
17	R	P	-1.0827
18	S	P	-1.1553
19	I	P	-0.4747
20	I	P	0.0000
21	R	P	-2.3486
22	S	P	-1.7887
23	R	P	-2.4961
24	S	P	-1.5763
25	V	P	-0.9852
26	A	P	-0.4685
27	W	P	0.0000
28	D	P	-2.2414
29	A	P	-1.5111
30	L	P	-1.5411
31	A	P	-2.5007
32	R	P	-3.2245
33	S	P	-2.1865
34	E	P	-3.1169
35	E	P	-2.4449
36	L	P	0.0000
37	S	P	-1.6457
38	E	P	-2.1028
39	I	P	0.3711
40	D	P	0.0000
41	A	P	0.0000
42	S	P	-0.9240
43	T	P	-0.7122
44	A	P	0.0000
45	K	P	-1.9743
46	A	P	-1.4747
47	L	P	0.0000
48	E	P	-1.7890
49	S	P	-1.4323
50	I	P	0.0000
51	L	P	-0.6186
52	V	P	0.2137
53	K	P	-2.2615
54	K	P	-3.0043
55	N	P	-2.7060
73	N	P	-2.9429
74	G	P	0.0000
75	K	P	-1.8468
76	T	P	-0.9401
77	L	P	0.0000
78	I	P	0.8007
79	P	P	0.4141
80	L	P	0.0000
81	I	P	0.0000
82	H	P	-0.4861
83	L	P	0.0000
84	L	P	0.0000
85	S	P	-1.2985
86	T	P	-0.8358
87	S	P	0.0000
88	D	P	-2.6829
89	N	P	-2.3535
90	E	P	-2.7366
91	D	P	-2.6254
92	C	P	0.0000
93	K	P	0.0000
94	K	P	-1.3200
95	S	P	-1.4487
96	V	P	0.0000
97	Q	P	0.0000
98	N	P	0.0000
99	L	P	-0.5972
100	I	P	0.0000
101	A	P	0.0000
102	E	P	-0.1978
103	L	P	0.0000
104	L	P	0.0000
105	S	P	0.0000
106	S	P	-1.7416
107	D	P	-2.9052
108	K	P	-2.5052
109	Y	P	-2.0826
110	G	P	0.0000
111	D	P	-2.2736
112	D	P	-2.7335
113	T	P	0.0000
114	V	P	0.0000
115	K	P	-2.3221
116	F	P	-1.6999
117	F	P	0.0000
118	Q	P	-2.0625
119	E	P	-2.6027
120	D	P	-2.2067
121	P	P	-2.3454
122	K	P	-2.9794
123	Q	P	-1.9646
124	L	P	0.0000
125	E	P	-3.3698
126	Q	P	-2.9224
127	L	P	0.0000
128	F	P	0.0000
129	D	P	-2.5384
130	V	P	0.0000
131	S	P	0.0000
132	L	P	-1.0856
133	K	P	-1.7641
134	G	P	-1.9685
135	D	P	-1.3725
136	F	P	-0.1646
137	Q	P	-0.0923
138	T	P	0.0000
139	V	P	0.0000
140	L	P	0.0000
141	I	P	0.0000
142	S	P	0.0000
143	G	P	0.0000
144	F	P	0.0000
145	N	P	0.0000
146	V	P	0.0000
147	V	P	0.0000
148	S	P	0.0000
149	L	P	0.0000
150	L	P	0.0000
151	V	P	-0.1571
152	Q	P	0.0000
153	N	P	-1.6101
154	G	P	-1.8748
155	L	P	0.0000
156	H	P	-1.5759
157	N	P	-1.4564
158	V	P	-1.1521
159	K	P	-1.7907
160	L	P	0.0000
161	V	P	0.0000
162	E	P	-1.7468
163	K	P	-2.1594
164	L	P	0.0000
165	L	P	0.0000
166	K	P	-2.5989
167	N	P	-2.4574
168	N	P	-2.8264
169	N	P	-2.5653
170	L	P	0.0000
171	I	P	0.0000
172	N	P	-2.5413
173	I	P	0.0000
174	L	P	0.0000
175	Q	P	-2.0606
176	N	P	-2.5003
177	I	P	0.0000
178	E	P	-2.6346
179	Q	P	-2.0282
180	M	P	-0.8911
181	D	P	-0.9679
182	T	P	0.0000
183	C	P	0.0000
184	Y	P	0.0000
185	V	P	0.0000
186	C	P	0.0000
187	I	P	0.0000
188	R	P	-0.2145
189	L	P	0.0000
190	L	P	0.0000
191	Q	P	0.0000
192	E	P	0.2701
193	L	P	0.0000
194	A	P	0.0000
195	V	P	1.1245
196	I	P	0.1083
197	P	P	-0.9197
198	E	P	-2.0058
199	Y	P	0.0000
200	R	P	-1.1057
201	D	P	-2.0250
202	V	P	0.0000
203	I	P	0.0000
204	W	P	-0.0605
205	L	P	0.5221
206	H	P	0.0000
207	E	P	0.0000
208	K	P	-1.8522
209	K	P	-1.9255
210	F	P	0.0000
211	M	P	0.0000
212	P	P	-1.4411
213	T	P	0.0000
214	L	P	0.0000
215	F	P	0.0000
216	K	P	-2.1864
217	I	P	0.0000
218	L	P	0.0000
219	Q	P	-2.0849
220	R	P	-1.8068
221	A	P	-1.3021
222	T	P	-1.7488
223	D	P	-2.3076
224	S	P	-1.5906
225	Q	P	-1.3683
226	L	P	-0.2536
227	A	P	-0.2797
228	T	P	-0.2836
229	R	P	-0.6775
230	I	P	1.8805
231	V	P	2.3762
232	A	P	0.7933
233	T	P	0.0000
234	N	P	0.0000
235	S	P	-0.2894
236	N	P	-0.4605
237	H	P	-1.1767
238	L	P	-0.2666
239	G	P	0.0000
240	I	P	-0.3560
241	Q	P	-0.4718
242	L	P	0.0000
243	Q	P	0.0000
244	Y	P	-0.0663
245	H	P	0.0000
246	S	P	0.0000
247	L	P	0.0000
248	L	P	0.3648
249	L	P	0.0000
250	I	P	0.0000
251	W	P	0.3807
252	L	P	0.0000
253	L	P	0.0000
254	T	P	0.0000
255	F	P	0.4335
256	N	P	-0.3843
257	P	P	-0.7779
258	V	P	-0.4409
259	F	P	-0.3851
260	A	P	0.0000
261	N	P	0.0000
262	E	P	-2.2799
263	L	P	0.0000
264	V	P	0.0000
265	Q	P	-2.2263
266	K	P	-2.5328
267	Y	P	0.0000
268	L	P	-0.9630
269	S	P	-0.7358
270	D	P	-1.5012
271	F	P	0.0000
272	L	P	-0.4175
273	D	P	-1.1233
274	L	P	0.0000
275	L	P	0.0000
276	K	P	-1.5430
277	L	P	0.0000
278	V	P	0.0000
279	K	P	-0.8731
280	I	P	-0.0033
281	T	P	0.0000
282	I	P	1.2562
283	K	P	-0.0341
284	E	P	-1.4991
285	K	P	-1.3449
286	V	P	0.0000
287	S	P	0.0000
288	R	P	-1.9943
289	L	P	0.0000
290	C	P	0.0000
291	I	P	0.0000
292	S	P	-0.6590
293	I	P	0.0000
294	I	P	0.0000
295	L	P	-0.2605
296	Q	P	-0.5353
297	C	P	0.0000
298	C	P	0.0000
299	S	P	-1.3781
300	T	P	-1.8332
301	R	P	-2.5549
302	V	P	0.0000
303	K	P	-3.2696
304	Q	P	-3.5615
305	H	P	-3.1486
306	K	P	-3.3855
307	K	P	-3.1553
308	V	P	0.0000
309	I	P	0.0000
310	K	P	-1.8328
311	Q	P	-0.8602
312	L	P	0.0000
313	L	P	0.0000
314	L	P	0.4332
315	L	P	1.1762
316	G	P	0.0210
317	N	P	-0.6664
318	A	P	0.0000
319	L	P	0.0000
320	P	P	-0.9574
321	T	P	-1.0044
322	V	P	0.0000
323	Q	P	-1.8375
324	S	P	-1.6143
325	L	P	0.0000
326	S	P	-2.5297
327	E	P	-3.2926
328	R	P	-3.2466
329	K	P	-3.3225
330	Y	P	-1.8352
331	S	P	-1.8190
332	D	P	-2.8786
333	E	P	-3.8070
334	E	P	-3.9117
335	L	P	0.0000
336	R	P	-4.1550
337	Q	P	-3.4143
338	D	P	-2.4730
339	I	P	0.0000
340	S	P	-2.0711
341	N	P	-2.2063
342	L	P	0.0000
343	K	P	-2.2630
344	E	P	-2.8521
345	I	P	-1.4236
346	L	P	0.0000
347	E	P	-2.4663
348	N	P	-2.7176
349	E	P	-2.2850
350	Y	P	0.0000
351	Q	P	-2.3979
352	E	P	-2.5614
353	L	P	-1.1946
354	T	P	-0.9656
355	S	P	-1.2475
356	F	P	-0.8574
357	D	P	-1.5171
358	E	P	-0.8853
359	Y	P	0.0000
360	V	P	-0.9435
361	A	P	-0.9660
362	E	P	-0.7781
363	L	P	0.0000
364	D	P	-2.0299
365	S	P	-1.1211
366	K	P	-1.1762
367	L	P	0.5218
368	L	P	0.0000
369	C	P	0.9071
370	W	P	0.8450
371	S	P	0.0000
372	P	P	-0.2004
373	P	P	-0.6870
374	H	P	0.0000
375	V	P	0.7686
376	D	P	-1.2076
377	N	P	-2.0679
378	G	P	-1.6350
379	F	P	0.0000
380	W	P	0.0000
381	S	P	-1.8356
382	D	P	-2.6036
383	N	P	0.0000
384	I	P	-1.6255
385	D	P	-3.2216
386	E	P	-2.8045
387	F	P	0.0000
388	K	P	-4.3080
389	K	P	-4.3433
390	D	P	-3.9579
391	N	P	-3.6282
392	Y	P	0.0000
393	K	P	-3.5179
394	I	P	-2.0013
395	F	P	0.0000
396	R	P	-2.2281
397	Q	P	-1.8206
398	L	P	0.0000
399	I	P	0.0000
400	E	P	-1.8166
401	L	P	0.0000
402	L	P	0.0000
403	Q	P	-1.6664
404	A	P	-1.8711
405	K	P	-2.2945
406	V	P	0.0000
407	R	P	-3.2651
408	N	P	-3.0996
409	G	P	-2.6942
410	D	P	-3.2880
411	V	P	-2.4037
412	N	P	-2.1118
413	A	P	-2.0336
414	K	P	-2.4397
415	Q	P	-1.8746
416	E	P	0.0000
417	K	P	-1.7133
418	I	P	-0.0501
419	I	P	0.0000
420	I	P	0.0000
421	Q	P	0.0000
422	V	P	0.0000
423	A	P	0.0000
424	L	P	0.0000
425	N	P	0.2993
426	D	P	0.0000
427	I	P	0.0000
428	T	P	0.0000
429	H	P	-0.9985
430	V	P	0.0000
431	V	P	0.0000
432	E	P	-1.8418
433	L	P	-0.7462
434	L	P	0.0000
435	P	P	-1.5088
436	E	P	-2.3145
437	S	P	0.0000
438	I	P	-2.0506
439	D	P	-3.3936
440	V	P	0.0000
441	L	P	0.0000
442	D	P	-3.3923
443	K	P	-3.1592
444	T	P	-2.3047
445	G	P	-1.7833
446	G	P	0.0000
447	K	P	-1.8042
448	A	P	-0.8968
449	D	P	-1.1256
450	I	P	0.0000
451	M	P	-0.3199
452	E	P	-1.6782
453	L	P	0.0000
454	L	P	-0.6105
455	N	P	-1.7994
456	H	P	-1.5866
457	S	P	-1.5645
458	D	P	-2.0233
459	S	P	-1.4815
460	R	P	-1.9064
461	V	P	0.0000
462	K	P	-1.4737
463	Y	P	0.1010
464	E	P	0.0000
465	A	P	0.0000
466	L	P	0.5708
467	K	P	-0.6568
468	A	P	0.0000
469	T	P	-0.2689
470	Q	P	-1.1820
471	A	P	0.0000
472	I	P	0.0000
473	I	P	0.4378
474	G	P	-0.3290
475	Y	P	-0.0499
476	T	P	0.8468
477	F	P	1.2883
478	K	P	-0.6773