Project name: daed10b62bdc616

Chain sequence(s)	A: QMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6561
• Maximal score value: 1.5573
• Average score: -0.7308
• Total score value: -144.6955

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
143	Q	A	-1.6024
144	M	A	-1.2935
145	T	A	-1.2240
146	R	A	-2.1136
147	Q	A	-1.9346
148	A	A	0.0000
149	R	A	-1.2172
150	R	A	-0.6007
151	L	A	0.0000
152	Y	A	-0.1852
153	V	A	0.0000
154	G	A	0.0000
155	N	A	-0.5839
156	I	A	0.0000
157	P	A	0.0000
158	F	A	0.9385
159	G	A	0.0986
160	I	A	0.0000
161	T	A	-1.2949
162	E	A	-2.5165
163	E	A	-2.8109
164	A	A	-1.7861
165	M	A	0.0000
166	M	A	-1.4743
167	D	A	-2.4351
168	F	A	-1.0279
169	F	A	0.0000
170	N	A	0.0000
171	A	A	-0.9245
172	Q	A	-0.6964
173	M	A	0.0000
174	R	A	-1.6098
175	L	A	0.3450
176	G	A	-0.4465
177	G	A	-0.8858
178	L	A	0.0000
179	T	A	-1.6342
180	Q	A	-1.8579
181	A	A	-1.0523
182	P	A	-1.0236
183	G	A	-1.2501
184	N	A	-1.5747
185	P	A	0.0000
186	V	A	0.0000
187	L	A	1.0817
188	A	A	0.1556
189	V	A	-0.4907
190	Q	A	-1.0766
191	I	A	-1.3790
192	N	A	-2.1485
193	Q	A	-2.6318
194	D	A	-3.2378
195	K	A	-3.2745
196	N	A	-1.9553
197	F	A	-1.1696
198	A	A	0.0000
199	F	A	0.0552
200	L	A	0.0000
201	E	A	0.0000
202	F	A	0.0000
203	R	A	-0.6768
204	S	A	-0.9651
205	V	A	-1.0942
206	D	A	-2.3422
207	E	A	0.0000
208	T	A	0.0000
209	T	A	-1.4145
210	Q	A	-0.8628
211	A	A	0.0000
212	M	A	-0.4206
213	A	A	0.3218
214	F	A	0.0000
215	D	A	0.0291
216	G	A	0.0000
217	I	A	0.0000
218	I	A	0.1534
219	F	A	0.0000
220	Q	A	-1.0810
221	G	A	-1.0671
222	Q	A	-0.9471
223	S	A	0.0000
224	L	A	0.0000
225	K	A	-0.4944
226	I	A	0.0000
227	R	A	-0.6369
228	R	A	-1.5016
229	P	A	0.0000
230	H	A	-2.1107
231	D	A	-2.5374
232	Y	A	-2.2672
233	Q	A	-2.0470
234	P	A	-1.2930
235	L	A	-0.3967
236	P	A	-0.4802
237	G	A	-0.6483
238	M	A	-0.9374
239	S	A	-1.5917
240	E	A	-2.6819
241	N	A	-2.2892
242	P	A	-1.0388
243	S	A	-0.1880
244	V	A	0.8647
245	Y	A	1.5573
246	V	A	0.7143
247	P	A	0.1080
248	G	A	-0.3194
249	V	A	0.2164
250	V	A	-0.0814
251	S	A	-0.0292
252	T	A	0.0000
253	V	A	0.9798
254	V	A	0.0393
255	P	A	-0.6787
256	D	A	-1.8813
257	S	A	-1.2678
258	A	A	-0.5120
259	H	A	-0.9649
260	K	A	0.0000
261	L	A	0.0000
262	F	A	0.7739
263	I	A	0.0000
264	G	A	0.0000
265	G	A	-1.2541
266	L	A	0.0000
267	P	A	-1.1224
268	N	A	-0.6161
269	Y	A	0.6882
270	L	A	-0.0591
271	N	A	-1.3196
272	D	A	0.0000
273	D	A	-1.9369
274	Q	A	-1.6886
275	V	A	0.0000
276	K	A	-1.8583
277	E	A	-2.4266
278	L	A	-1.0181
279	L	A	0.0000
280	T	A	-0.7671
281	S	A	-0.5466
282	F	A	-0.2516
283	G	A	-0.4896
284	P	A	-0.9055
285	L	A	0.0000
286	K	A	-1.2552
287	A	A	0.0000
288	F	A	0.0000
289	N	A	0.0035
290	L	A	0.0000
291	V	A	-0.3319
292	K	A	-1.0643
293	D	A	-1.0749
294	S	A	-1.3615
295	A	A	-0.7698
296	T	A	-0.4213
297	G	A	-0.7353
298	L	A	-0.1688
299	S	A	0.0000
300	K	A	-1.4060
301	G	A	0.0000
302	Y	A	0.1747
303	A	A	0.0000
304	F	A	0.3930
305	C	A	0.0000
306	E	A	-0.5845
307	Y	A	0.0000
308	V	A	-0.0779
309	D	A	-0.8358
310	I	A	-0.1108
311	N	A	-1.4029
312	V	A	-1.1412
313	T	A	0.0000
314	D	A	-2.5063
315	Q	A	-2.2568
316	A	A	0.0000
317	I	A	-1.0753
318	A	A	-1.2724
319	G	A	-1.0872
320	L	A	0.0000
321	N	A	-1.2329
322	G	A	-1.2122
323	M	A	-1.2690
324	Q	A	-2.6865
325	L	A	-2.0380
326	G	A	-2.2288
327	D	A	-3.3733
328	K	A	-3.6561
329	K	A	-3.2563
330	L	A	0.0000
331	L	A	0.2667
332	V	A	0.0000
333	Q	A	-0.3622
334	R	A	-0.5748
335	A	A	0.0000
336	S	A	-0.2021
337	V	A	1.0669
338	G	A	-0.1400
339	A	A	-0.5380
340	K	A	-1.5837