Project name: 3A5 Protein Analysis
Status: done
submitted: 2018-11-07 01:37:50, status changed: 2018-11-07 01:44:14
Settings
|
Chain sequence(s)
|
A: MSVGLLWLGFTLLGALHTQARSSSSRLLRAPPLSKIPLQPNFQADQFQGKWYTVGVAGNAIKKEEQDPLKMYSSNYELKEDGSYNVTSILLKDDLCDYWIRTFVPSSQPGQFTLGNIKSYRGIRSYTVRVVNTDYNQFAIVYFKKVQRKKTYFKITLYGRTKELTPEVRENFINFAKSLGLTDDHIVFTVPIDRCIDD
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4862
-
Maximal score value
-
2.6378
-
Average score
-
-0.7762
-
Total score value
-
-153.6958
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
M |
A |
2.0007 |
|
| 2 |
S |
A |
1.6273 |
|
| 3 |
V |
A |
2.6378 |
|
| 4 |
G |
A |
2.1718 |
|
| 5 |
L |
A |
2.4604 |
|
| 6 |
L |
A |
2.2857 |
|
| 7 |
W |
A |
2.3116 |
|
| 8 |
L |
A |
1.4483 |
|
| 9 |
G |
A |
0.0000 |
|
| 10 |
F |
A |
0.8197 |
|
| 11 |
T |
A |
0.0000 |
|
| 12 |
L |
A |
1.3242 |
|
| 13 |
L |
A |
1.2957 |
|
| 14 |
G |
A |
0.0000 |
|
| 15 |
A |
A |
0.3338 |
|
| 16 |
L |
A |
0.1149 |
|
| 17 |
H |
A |
-0.6331 |
|
| 18 |
T |
A |
-0.7002 |
|
| 19 |
Q |
A |
-1.1605 |
|
| 20 |
A |
A |
-1.3075 |
|
| 21 |
R |
A |
-2.1286 |
|
| 22 |
S |
A |
-1.5452 |
|
| 23 |
S |
A |
-1.3633 |
|
| 24 |
S |
A |
-1.2881 |
|
| 25 |
S |
A |
-1.3221 |
|
| 26 |
R |
A |
-1.9044 |
|
| 27 |
L |
A |
-0.7137 |
|
| 28 |
L |
A |
-0.7661 |
|
| 29 |
R |
A |
-1.7696 |
|
| 30 |
A |
A |
-0.7145 |
|
| 31 |
P |
A |
0.0000 |
|
| 32 |
P |
A |
-0.9204 |
|
| 33 |
L |
A |
-0.5651 |
|
| 34 |
S |
A |
-1.0213 |
|
| 35 |
K |
A |
-1.8705 |
|
| 36 |
I |
A |
0.0000 |
|
| 37 |
P |
A |
-0.7622 |
|
| 38 |
L |
A |
-0.5004 |
|
| 39 |
Q |
A |
-1.3089 |
|
| 40 |
P |
A |
-1.2418 |
|
| 41 |
N |
A |
-1.8994 |
|
| 42 |
F |
A |
0.0000 |
|
| 43 |
Q |
A |
-2.2744 |
|
| 44 |
A |
A |
-1.8786 |
|
| 45 |
D |
A |
-2.4424 |
|
| 46 |
Q |
A |
-2.0824 |
|
| 47 |
F |
A |
0.0000 |
|
| 48 |
Q |
A |
-1.5716 |
|
| 49 |
G |
A |
-1.0752 |
|
| 50 |
K |
A |
-1.3717 |
|
| 51 |
W |
A |
0.0000 |
|
| 52 |
Y |
A |
-1.0405 |
|
| 53 |
T |
A |
0.0000 |
|
| 54 |
V |
A |
0.0000 |
|
| 55 |
G |
A |
0.0000 |
|
| 56 |
V |
A |
0.0000 |
|
| 57 |
A |
A |
0.0000 |
|
| 58 |
G |
A |
0.0000 |
|
| 59 |
N |
A |
0.0000 |
|
| 60 |
A |
A |
-0.7400 |
|
| 61 |
I |
A |
0.0000 |
|
| 62 |
K |
A |
-2.1648 |
|
| 63 |
K |
A |
-2.5722 |
|
| 64 |
E |
A |
-2.9100 |
|
| 65 |
E |
A |
-3.4728 |
|
| 66 |
Q |
A |
-2.4300 |
|
| 67 |
D |
A |
0.0000 |
|
| 68 |
P |
A |
-1.1317 |
|
| 69 |
L |
A |
-0.4265 |
|
| 70 |
K |
A |
-0.4483 |
|
| 71 |
M |
A |
0.0000 |
|
| 72 |
Y |
A |
-0.0907 |
|
| 73 |
S |
A |
0.0000 |
|
| 74 |
S |
A |
0.0000 |
|
| 75 |
N |
A |
0.0000 |
|
| 76 |
Y |
A |
0.0000 |
|
| 77 |
E |
A |
-1.4296 |
|
| 78 |
L |
A |
-1.6495 |
|
| 79 |
K |
A |
-2.4967 |
|
| 80 |
E |
A |
-3.1790 |
|
| 81 |
D |
A |
-2.9590 |
|
| 82 |
G |
A |
-1.9804 |
|
| 83 |
S |
A |
-1.2789 |
|
| 84 |
Y |
A |
0.0000 |
|
| 85 |
N |
A |
-0.4269 |
|
| 86 |
V |
A |
0.0000 |
|
| 87 |
T |
A |
0.7030 |
|
| 88 |
S |
A |
0.0000 |
|
| 89 |
I |
A |
0.0000 |
|
| 90 |
L |
A |
0.5290 |
|
| 91 |
L |
A |
-0.2368 |
|
| 92 |
K |
A |
-0.9386 |
|
| 93 |
D |
A |
-2.1947 |
|
| 94 |
D |
A |
-2.0498 |
|
| 95 |
L |
A |
0.1768 |
|
| 96 |
C |
A |
0.3998 |
|
| 97 |
D |
A |
0.0000 |
|
| 98 |
Y |
A |
1.6137 |
|
| 99 |
W |
A |
0.0000 |
|
| 100 |
I |
A |
1.9627 |
|
| 101 |
R |
A |
0.0000 |
|
| 102 |
T |
A |
-0.0938 |
|
| 103 |
F |
A |
0.0000 |
|
| 104 |
V |
A |
-0.1875 |
|
| 105 |
P |
A |
-0.3929 |
|
| 106 |
S |
A |
-0.3632 |
|
| 107 |
S |
A |
-0.4968 |
|
| 108 |
Q |
A |
-0.7040 |
|
| 109 |
P |
A |
-0.9330 |
|
| 110 |
G |
A |
0.0000 |
|
| 111 |
Q |
A |
-0.3462 |
|
| 112 |
F |
A |
0.0000 |
|
| 113 |
T |
A |
-0.1201 |
|
| 114 |
L |
A |
0.0000 |
|
| 115 |
G |
A |
-0.8457 |
|
| 116 |
N |
A |
-1.7047 |
|
| 117 |
I |
A |
-1.6100 |
|
| 118 |
K |
A |
-2.5014 |
|
| 119 |
S |
A |
-1.6550 |
|
| 120 |
Y |
A |
-1.8354 |
|
| 121 |
R |
A |
-2.5542 |
|
| 122 |
G |
A |
-2.3416 |
|
| 123 |
I |
A |
0.0000 |
|
| 124 |
R |
A |
-2.9018 |
|
| 125 |
S |
A |
-0.8812 |
|
| 126 |
Y |
A |
0.0000 |
|
| 127 |
T |
A |
0.0000 |
|
| 128 |
V |
A |
0.0000 |
|
| 129 |
R |
A |
-0.4580 |
|
| 130 |
V |
A |
0.0000 |
|
| 131 |
V |
A |
0.0000 |
|
| 132 |
N |
A |
-1.5561 |
|
| 133 |
T |
A |
0.0000 |
|
| 134 |
D |
A |
-1.7418 |
|
| 135 |
Y |
A |
-1.2250 |
|
| 136 |
N |
A |
-1.8635 |
|
| 137 |
Q |
A |
-2.0518 |
|
| 138 |
F |
A |
0.0000 |
|
| 139 |
A |
A |
0.0000 |
|
| 140 |
I |
A |
0.0000 |
|
| 141 |
V |
A |
0.0000 |
|
| 142 |
Y |
A |
0.0000 |
|
| 143 |
F |
A |
0.0947 |
|
| 144 |
K |
A |
-0.0321 |
|
| 145 |
K |
A |
0.0000 |
|
| 146 |
V |
A |
-1.3364 |
|
| 147 |
Q |
A |
-2.4659 |
|
| 148 |
R |
A |
-3.4862 |
|
| 149 |
K |
A |
-3.0986 |
|
| 150 |
K |
A |
-2.2348 |
|
| 151 |
T |
A |
-1.2754 |
|
| 152 |
Y |
A |
-0.1486 |
|
| 153 |
F |
A |
0.0000 |
|
| 154 |
K |
A |
-0.1524 |
|
| 155 |
I |
A |
0.0000 |
|
| 156 |
T |
A |
0.0000 |
|
| 157 |
L |
A |
0.0000 |
|
| 158 |
Y |
A |
0.0000 |
|
| 159 |
G |
A |
0.0000 |
|
| 160 |
R |
A |
-2.0078 |
|
| 161 |
T |
A |
-2.0488 |
|
| 162 |
K |
A |
-2.1440 |
|
| 163 |
E |
A |
-2.3159 |
|
| 164 |
L |
A |
-1.4518 |
|
| 165 |
T |
A |
-1.4976 |
|
| 166 |
P |
A |
-2.0168 |
|
| 167 |
E |
A |
-2.8172 |
|
| 168 |
V |
A |
-2.0967 |
|
| 169 |
R |
A |
-2.2629 |
|
| 170 |
E |
A |
-3.2880 |
|
| 171 |
N |
A |
-2.4861 |
|
| 172 |
F |
A |
0.0000 |
|
| 173 |
I |
A |
-1.5941 |
|
| 174 |
N |
A |
-2.2798 |
|
| 175 |
F |
A |
-0.9556 |
|
| 176 |
A |
A |
0.0000 |
|
| 177 |
K |
A |
-1.8044 |
|
| 178 |
S |
A |
-1.1191 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
G |
A |
-1.2184 |
|
| 181 |
L |
A |
0.0000 |
|
| 182 |
T |
A |
-1.8207 |
|
| 183 |
D |
A |
-2.3429 |
|
| 184 |
D |
A |
-3.2305 |
|
| 185 |
H |
A |
-2.1298 |
|
| 186 |
I |
A |
0.0000 |
|
| 187 |
V |
A |
0.0000 |
|
| 188 |
F |
A |
0.5581 |
|
| 189 |
T |
A |
0.3086 |
|
| 190 |
V |
A |
0.1722 |
|
| 191 |
P |
A |
-0.7066 |
|
| 192 |
I |
A |
-1.2074 |
|
| 193 |
D |
A |
-2.3678 |
|
| 194 |
R |
A |
-1.8897 |
|
| 195 |
C |
A |
-0.9360 |
|
| 196 |
I |
A |
0.0000 |
|
| 197 |
D |
A |
-2.8691 |
|
| 198 |
D |
A |
-2.1951 |
|