Project name: 4od2:B
Status: done
submitted: 2019-03-20 15:45:11, status changed: 2019-03-20 17:20:46
Settings
|
Chain sequence(s)
|
B: EVQLVQSGGGVERPGGSLRLSCAASGFTFDDYAMSWVRQAPGKGLEWVSGINWQGGSTGYADSVKGRVTISRDNAKNSLYLQMNSLRAEDTAVYYCAKILGAGRGWYFDYWGKGTTVTVSSASTKGPSVFPLAPTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8711
-
Maximal score value
-
1.9842
-
Average score
-
-0.6292
-
Total score value
-
-134.6488
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
B |
-2.1047 |
|
| 2 |
V |
B |
-1.3760 |
|
| 3 |
Q |
B |
-1.2067 |
|
| 4 |
L |
B |
0.1835 |
|
| 5 |
V |
B |
1.2139 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.5798 |
|
| 8 |
G |
B |
-0.9193 |
|
| 9 |
G |
B |
-0.4505 |
|
| 10 |
G |
B |
-0.1597 |
|
| 11 |
V |
B |
0.8950 |
|
| 12 |
E |
B |
-0.9248 |
|
| 13 |
R |
B |
-2.2082 |
|
| 14 |
P |
B |
-1.9490 |
|
| 15 |
G |
B |
-1.7312 |
|
| 16 |
G |
B |
-1.4064 |
|
| 17 |
S |
B |
-1.7089 |
|
| 18 |
L |
B |
-1.4025 |
|
| 19 |
R |
B |
-2.4886 |
|
| 20 |
L |
B |
0.0000 |
|
| 21 |
S |
B |
-0.5165 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
A |
B |
-0.1307 |
|
| 24 |
A |
B |
0.0000 |
|
| 25 |
S |
B |
-0.9704 |
|
| 26 |
G |
B |
-1.2938 |
|
| 27 |
F |
B |
-0.9632 |
|
| 28 |
T |
B |
-0.8679 |
|
| 29 |
F |
B |
0.0000 |
|
| 30 |
D |
B |
-2.3126 |
|
| 31 |
D |
B |
-1.8777 |
|
| 32 |
Y |
B |
-0.8819 |
|
| 33 |
A |
B |
0.0000 |
|
| 34 |
M |
B |
0.0000 |
|
| 35 |
S |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.5188 |
|
| 40 |
A |
B |
-1.0793 |
|
| 41 |
P |
B |
-0.8830 |
|
| 42 |
G |
B |
-1.3984 |
|
| 43 |
K |
B |
-2.0745 |
|
| 44 |
G |
B |
-0.9697 |
|
| 45 |
L |
B |
0.4284 |
|
| 46 |
E |
B |
-0.4325 |
|
| 47 |
W |
B |
0.2187 |
|
| 48 |
V |
B |
0.0000 |
|
| 49 |
S |
B |
0.0000 |
|
| 50 |
G |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
N |
B |
-1.6042 |
|
| 53 |
W |
B |
-1.3528 |
|
| 54 |
Q |
B |
-1.8598 |
|
| 55 |
G |
B |
-1.4533 |
|
| 56 |
G |
B |
-1.1845 |
|
| 57 |
S |
B |
-1.0861 |
|
| 58 |
T |
B |
-0.6077 |
|
| 59 |
G |
B |
-0.7725 |
|
| 60 |
Y |
B |
-0.9382 |
|
| 61 |
A |
B |
-1.4419 |
|
| 62 |
D |
B |
-2.5182 |
|
| 63 |
S |
B |
-1.9205 |
|
| 64 |
V |
B |
0.0000 |
|
| 65 |
K |
B |
-2.6344 |
|
| 66 |
G |
B |
-1.8665 |
|
| 67 |
R |
B |
-2.0005 |
|
| 68 |
V |
B |
0.0000 |
|
| 69 |
T |
B |
-1.2415 |
|
| 70 |
I |
B |
0.0000 |
|
| 71 |
S |
B |
-0.7769 |
|
| 72 |
R |
B |
0.0000 |
|
| 73 |
D |
B |
-2.0229 |
|
| 74 |
N |
B |
-2.1971 |
|
| 75 |
A |
B |
-1.5729 |
|
| 76 |
K |
B |
-2.4893 |
|
| 77 |
N |
B |
-2.0271 |
|
| 78 |
S |
B |
0.0000 |
|
| 79 |
L |
B |
0.0000 |
|
| 80 |
Y |
B |
-0.7634 |
|
| 81 |
L |
B |
0.0000 |
|
| 82 |
Q |
B |
-2.1271 |
|
| 83 |
M |
B |
0.0000 |
|
| 84 |
N |
B |
-2.2382 |
|
| 85 |
S |
B |
-1.5947 |
|
| 86 |
L |
B |
0.0000 |
|
| 87 |
R |
B |
-2.3552 |
|
| 88 |
A |
B |
-1.8322 |
|
| 89 |
E |
B |
-2.1845 |
|
| 90 |
D |
B |
0.0000 |
|
| 91 |
T |
B |
-0.7280 |
|
| 92 |
A |
B |
0.0000 |
|
| 93 |
V |
B |
0.0211 |
|
| 94 |
Y |
B |
0.0000 |
|
| 95 |
Y |
B |
0.2928 |
|
| 96 |
C |
B |
0.0000 |
|
| 97 |
A |
B |
0.0000 |
|
| 98 |
K |
B |
0.0000 |
|
| 99 |
I |
B |
0.0000 |
|
| 100 |
L |
B |
0.6414 |
|
| 101 |
G |
B |
-0.1365 |
|
| 102 |
A |
B |
-0.9864 |
|
| 103 |
G |
B |
-1.3054 |
|
| 104 |
R |
B |
-1.5444 |
|
| 105 |
G |
B |
0.0592 |
|
| 106 |
W |
B |
1.4290 |
|
| 107 |
Y |
B |
1.6226 |
|
| 108 |
F |
B |
0.8944 |
|
| 109 |
D |
B |
-0.3733 |
|
| 110 |
Y |
B |
0.0401 |
|
| 111 |
W |
B |
0.1765 |
|
| 112 |
G |
B |
0.0000 |
|
| 113 |
K |
B |
-1.2508 |
|
| 114 |
G |
B |
-0.5573 |
|
| 115 |
T |
B |
0.0000 |
|
| 116 |
T |
B |
-0.2452 |
|
| 117 |
V |
B |
0.0000 |
|
| 118 |
T |
B |
-0.2250 |
|
| 119 |
V |
B |
0.0000 |
|
| 120 |
S |
B |
-0.9456 |
|
| 121 |
S |
B |
-1.0667 |
|
| 122 |
A |
B |
-0.5977 |
|
| 123 |
S |
B |
-0.6365 |
|
| 124 |
T |
B |
-0.6354 |
|
| 125 |
K |
B |
-1.0389 |
|
| 126 |
G |
B |
-1.3689 |
|
| 127 |
P |
B |
-0.5661 |
|
| 128 |
S |
B |
-0.1562 |
|
| 129 |
V |
B |
0.0000 |
|
| 130 |
F |
B |
1.5898 |
|
| 131 |
P |
B |
0.4099 |
|
| 132 |
L |
B |
0.3946 |
|
| 133 |
A |
B |
-0.7697 |
|
| 134 |
P |
B |
-0.7482 |
|
| 143 |
T |
B |
-0.2679 |
|
| 144 |
A |
B |
-0.1651 |
|
| 145 |
A |
B |
0.0565 |
|
| 146 |
L |
B |
0.0000 |
|
| 147 |
G |
B |
0.0000 |
|
| 148 |
C |
B |
0.0000 |
|
| 149 |
L |
B |
0.8254 |
|
| 150 |
V |
B |
0.0000 |
|
| 151 |
K |
B |
-0.4098 |
|
| 152 |
D |
B |
-0.5617 |
|
| 153 |
Y |
B |
0.0000 |
|
| 154 |
F |
B |
-0.4910 |
|
| 155 |
P |
B |
-0.7736 |
|
| 156 |
E |
B |
-1.1107 |
|
| 157 |
P |
B |
-1.0033 |
|
| 158 |
V |
B |
-0.4884 |
|
| 159 |
T |
B |
-0.4774 |
|
| 160 |
V |
B |
0.0342 |
|
| 161 |
S |
B |
-0.3653 |
|
| 162 |
W |
B |
0.0000 |
|
| 163 |
N |
B |
-0.8173 |
|
| 164 |
S |
B |
-0.6224 |
|
| 165 |
G |
B |
-0.3782 |
|
| 166 |
A |
B |
-0.1805 |
|
| 167 |
L |
B |
0.0079 |
|
| 168 |
T |
B |
-0.1770 |
|
| 169 |
S |
B |
-0.2770 |
|
| 170 |
G |
B |
-0.2824 |
|
| 171 |
V |
B |
0.0351 |
|
| 172 |
H |
B |
-0.2838 |
|
| 173 |
T |
B |
0.3781 |
|
| 174 |
F |
B |
1.2352 |
|
| 175 |
P |
B |
0.7421 |
|
| 176 |
A |
B |
0.9812 |
|
| 177 |
V |
B |
1.9842 |
|
| 178 |
L |
B |
1.1261 |
|
| 179 |
Q |
B |
0.1670 |
|
| 180 |
S |
B |
-0.1710 |
|
| 181 |
S |
B |
-0.3843 |
|
| 182 |
G |
B |
0.0594 |
|
| 183 |
L |
B |
-0.0145 |
|
| 184 |
Y |
B |
0.3514 |
|
| 185 |
S |
B |
0.3692 |
|
| 186 |
L |
B |
0.0000 |
|
| 187 |
S |
B |
0.7548 |
|
| 188 |
S |
B |
0.0000 |
|
| 189 |
V |
B |
0.5998 |
|
| 190 |
V |
B |
0.0000 |
|
| 191 |
T |
B |
-0.1692 |
|
| 192 |
V |
B |
0.0000 |
|
| 193 |
P |
B |
-0.3976 |
|
| 194 |
S |
B |
-0.4636 |
|
| 195 |
S |
B |
-0.6213 |
|
| 196 |
S |
B |
-0.7103 |
|
| 197 |
L |
B |
-0.7864 |
|
| 198 |
G |
B |
-0.9783 |
|
| 199 |
T |
B |
-0.8681 |
|
| 200 |
Q |
B |
-1.4786 |
|
| 201 |
T |
B |
-1.2401 |
|
| 202 |
Y |
B |
0.0000 |
|
| 203 |
I |
B |
-1.5590 |
|
| 204 |
C |
B |
0.0000 |
|
| 205 |
N |
B |
-1.4736 |
|
| 206 |
V |
B |
0.0000 |
|
| 207 |
N |
B |
-1.7941 |
|
| 208 |
H |
B |
0.0000 |
|
| 209 |
K |
B |
-2.7989 |
|
| 210 |
P |
B |
-1.7571 |
|
| 211 |
S |
B |
-1.8026 |
|
| 212 |
N |
B |
-2.5847 |
|
| 213 |
T |
B |
-2.0769 |
|
| 214 |
K |
B |
-2.7622 |
|
| 215 |
V |
B |
-1.8880 |
|
| 216 |
D |
B |
-2.7906 |
|
| 217 |
K |
B |
-2.2487 |
|
| 218 |
K |
B |
-2.4519 |
|
| 219 |
V |
B |
0.0000 |
|
| 220 |
E |
B |
-2.8711 |
|
| 221 |
P |
B |
-2.0398 |
|
| 222 |
K |
B |
-2.2185 |
|