Project name: FISH

Chain sequence(s)	A: MRTAVLRMMAALMCVVAVCADVMPMQDFSLEKMAGKWYLLGFASNAQWFVEHRDTMKAGTAMFTPTEVGDLDLSYSNLNTDGTCWRMTHLAKKTDTPGRFTFHSQAWNNDNDMRIVDVVYDNYALTYTIKTKEGVSEVLIKLYSRSTEVSADLQQKFTQFSQNNGVLTENIVILPKNECPEAAANPAS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3106
• Maximal score value: 2.0217
• Average score: -0.6571
• Total score value: -123.5343

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.1247
2	R	A	-0.9622
3	T	A	-0.5705
4	A	A	0.1290
5	V	A	0.0000
6	L	A	1.1369
7	R	A	-0.4193
8	M	A	1.1829
9	M	A	1.0599
10	A	A	0.1940
11	A	A	0.5894
12	L	A	1.7068
13	M	A	2.0217
14	C	A	1.7830
15	V	A	1.6418
16	V	A	0.0000
17	A	A	0.0000
18	V	A	0.0000
19	C	A	0.0000
20	A	A	-0.3943
21	D	A	-1.3480
22	V	A	-0.1791
23	M	A	0.6296
24	P	A	-0.0411
25	M	A	-0.5466
26	Q	A	-1.8487
27	D	A	-2.2767
28	F	A	-1.5592
29	S	A	-1.6744
30	L	A	-1.3247
31	E	A	-2.5457
32	K	A	-2.4556
33	M	A	0.0000
34	A	A	-1.3335
35	G	A	-1.1606
36	K	A	-1.1298
37	W	A	0.0000
38	Y	A	-0.3601
39	L	A	0.0000
40	L	A	0.0000
41	G	A	0.0000
42	F	A	0.0000
43	A	A	0.0000
44	S	A	0.0000
45	N	A	-1.2757
46	A	A	-0.8659
47	Q	A	-1.6358
48	W	A	-0.1925
49	F	A	-0.3873
50	V	A	-1.4369
51	E	A	-2.1358
52	H	A	-1.7012
53	R	A	-1.5514
54	D	A	-1.2980
55	T	A	-1.1294
56	M	A	-0.6844
57	K	A	-1.3456
58	A	A	-0.8512
59	G	A	0.0000
60	T	A	-0.4121
61	A	A	0.0000
62	M	A	-0.1216
63	F	A	0.0000
64	T	A	-0.6913
65	P	A	-0.9576
66	T	A	-0.7857
67	E	A	-1.0817
68	V	A	0.6836
69	G	A	-0.3446
70	D	A	0.0000
71	L	A	0.0000
72	D	A	-0.3989
73	L	A	0.0000
74	S	A	-0.0968
75	Y	A	0.0837
76	S	A	-0.0737
77	N	A	-0.0037
78	L	A	-0.5241
79	N	A	-1.0294
80	T	A	-1.2053
81	D	A	-2.1976
82	G	A	-1.3433
83	T	A	-0.9583
84	C	A	0.0000
85	W	A	0.3074
86	R	A	-0.3518
87	M	A	0.2050
88	T	A	0.0035
89	H	A	0.0000
90	L	A	0.0540
91	A	A	0.0000
92	K	A	-0.9642
93	K	A	-1.3078
94	T	A	-1.6448
95	D	A	-2.1874
96	T	A	-1.6173
97	P	A	-1.5503
98	G	A	0.0000
99	R	A	-1.1727
100	F	A	0.0000
101	T	A	-0.6182
102	F	A	-0.4122
103	H	A	-1.1575
104	S	A	-0.9310
105	Q	A	-1.3952
106	A	A	-0.4444
107	W	A	0.2041
108	N	A	-1.7729
109	N	A	-1.9626
110	D	A	-1.7532
111	N	A	0.0000
112	D	A	-0.6342
113	M	A	0.0000
114	R	A	0.0000
115	I	A	0.0000
116	V	A	0.0000
117	D	A	0.2666
118	V	A	0.2190
119	V	A	0.2311
120	Y	A	-1.0997
121	D	A	-1.7435
122	N	A	-1.7598
123	Y	A	-0.5189
124	A	A	0.0000
125	L	A	0.0000
126	T	A	0.0000
127	Y	A	0.0000
128	T	A	0.0000
129	I	A	0.0000
130	K	A	-1.2274
131	T	A	-1.4210
132	K	A	-2.4146
133	E	A	-2.5671
134	G	A	-1.0100
135	V	A	0.1751
136	S	A	-0.3774
137	E	A	-0.8966
138	V	A	-0.5350
139	L	A	-0.0895
140	I	A	0.0000
141	K	A	0.0133
142	L	A	0.0000
143	Y	A	0.0000
144	S	A	0.0000
145	R	A	-1.9608
146	S	A	-1.6363
147	T	A	-1.5130
148	E	A	-2.2344
149	V	A	-1.3702
150	S	A	-1.3158
151	A	A	-1.4887
152	D	A	-2.4482
153	L	A	0.0000
154	Q	A	-1.4426
155	Q	A	-2.4796
156	K	A	-2.0648
157	F	A	0.0000
158	T	A	-1.3552
159	Q	A	-1.9043
160	F	A	0.0000
161	S	A	0.0000
162	Q	A	-1.2326
163	N	A	-1.1341
164	N	A	0.0000
165	G	A	-0.7760
166	V	A	0.0000
167	L	A	0.3369
168	T	A	-0.4431
169	E	A	-1.4724
170	N	A	0.0000
171	I	A	0.0068
172	V	A	0.0000
173	I	A	0.9274
174	L	A	0.0000
175	P	A	-1.3988
176	K	A	-2.9259
177	N	A	-3.0786
178	E	A	-3.3106
179	C	A	-1.9940
180	P	A	-1.7738
181	E	A	-2.2238
182	A	A	-1.0918
183	A	A	-0.8749
184	A	A	-0.9996
185	N	A	-1.3189
186	P	A	-0.9004
187	A	A	-0.4699
188	S	A	-0.4333