Project name: ALLK

Chain sequence(s)	A: MLSSDVMRRSYSSSPTREEQLEGPEGGVRHSYPQFSRILWMLDDGSQDKMTHSGWSMGKVGQRVNRAFSLSSNTLQSSSCSVAMVLGQLCLGLALLGALNIQAQDSISAIIPSPPLSKILLQPDLQYDQFQGKWYVIAWAQNTAWNESLSRAALYSVTYRLNSNNSYSVTSDWFSPTGCVHMSNPIVPSDQPSQFTLENITSFEGLQNFTMTVVETDYNQFSIVSFNMTLKNRVYFELILYGRTKKLIPKVKDHYHKLAKSLDIPDCHIIFTDPLGKDHLEWWSSGTKCPPRQVFSQGLPG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.3368
• Maximal score value: 1.9248
• Average score: -0.6485
• Total score value: -195.186

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.9112
2	L	A	1.5383
3	S	A	0.3223
4	S	A	-0.2454
5	D	A	-0.5345
6	V	A	0.0000
7	M	A	-0.2283
8	R	A	-2.0333
9	R	A	-1.8264
10	S	A	0.0000
11	Y	A	-1.2514
12	S	A	-1.5422
13	S	A	-2.2858
14	S	A	0.0000
15	P	A	-3.4331
16	T	A	0.0000
17	R	A	-3.3854
18	E	A	-3.7109
19	E	A	-4.3368
20	Q	A	-3.1792
21	L	A	-2.4537
22	E	A	-3.7649
23	G	A	-2.8170
24	P	A	-1.9360
25	E	A	-3.1667
26	G	A	0.0000
27	G	A	0.0000
28	V	A	0.0000
29	R	A	-1.2611
30	H	A	0.0000
31	S	A	0.0000
32	Y	A	0.0000
33	P	A	0.0000
34	Q	A	1.0570
35	F	A	1.9248
36	S	A	0.9114
37	R	A	0.7527
38	I	A	0.0000
39	L	A	0.0000
40	W	A	0.2260
41	M	A	0.0749
42	L	A	0.0000
43	D	A	0.0000
44	D	A	-1.8072
45	G	A	0.0000
46	S	A	0.0000
47	Q	A	-2.6978
48	D	A	-2.9487
49	K	A	-2.6358
50	M	A	-1.3442
51	T	A	-1.5260
52	H	A	-1.8273
53	S	A	-1.8809
54	G	A	-1.3393
55	W	A	0.0000
56	S	A	-0.6943
57	M	A	-0.7727
58	G	A	0.0000
59	K	A	-1.6846
60	V	A	0.0000
61	G	A	0.0000
62	Q	A	-2.6500
63	R	A	-3.4458
64	V	A	-2.2998
65	N	A	-2.7093
66	R	A	-3.5878
67	A	A	-2.0913
68	F	A	0.0000
69	S	A	0.0000
70	L	A	-0.9947
71	S	A	-0.8614
72	S	A	-1.5114
73	N	A	-1.7499
74	T	A	-0.8272
75	L	A	0.0000
76	Q	A	-1.9302
77	S	A	-0.7014
78	S	A	-0.2307
79	S	A	0.3492
80	C	A	0.8287
81	S	A	0.0243
82	V	A	0.0000
83	A	A	0.2040
84	M	A	0.8773
85	V	A	1.0744
86	L	A	0.9951
87	G	A	0.0000
88	Q	A	-0.3792
89	L	A	0.2286
90	C	A	0.0000
91	L	A	0.0000
92	G	A	0.0000
93	L	A	0.0000
94	A	A	0.0000
95	L	A	0.0000
96	L	A	0.0000
97	G	A	0.0000
98	A	A	0.0000
99	L	A	-0.8171
100	N	A	0.0000
101	I	A	0.0505
102	Q	A	-0.5122
103	A	A	0.0000
104	Q	A	-0.4911
105	D	A	-0.4760
106	S	A	0.0000
107	I	A	0.0130
108	S	A	-0.1961
109	A	A	0.5641
110	I	A	0.8547
111	I	A	0.8651
112	P	A	-0.0362
113	S	A	0.0118
114	P	A	-0.6474
115	P	A	-0.5298
116	L	A	-0.0858
117	S	A	-0.3548
118	K	A	-0.8848
119	I	A	0.3946
120	L	A	1.3529
121	L	A	0.3674
122	Q	A	-0.7814
123	P	A	-1.1236
124	D	A	-2.4131
125	L	A	0.0000
126	Q	A	-2.4649
127	Y	A	-1.9828
128	D	A	-2.6294
129	Q	A	-1.9444
130	F	A	0.0000
131	Q	A	-1.9296
132	G	A	-1.2919
133	K	A	-1.0833
134	W	A	0.0000
135	Y	A	0.0000
136	V	A	0.0000
137	I	A	0.0000
138	A	A	0.0000
139	W	A	0.0000
140	A	A	0.0000
141	Q	A	0.0000
142	N	A	0.0000
143	T	A	0.0000
144	A	A	0.0000
145	W	A	0.0000
146	N	A	0.0000
147	E	A	0.0000
148	S	A	0.0000
149	L	A	0.0000
150	S	A	0.0000
151	R	A	0.0000
152	A	A	0.0000
153	A	A	0.0000
154	L	A	0.0000
155	Y	A	0.0000
156	S	A	0.0000
157	V	A	0.0000
158	T	A	0.0000
159	Y	A	0.0000
160	R	A	-2.1102
161	L	A	-1.7303
162	N	A	-2.1225
163	S	A	-1.5495
164	N	A	-1.7210
165	N	A	-1.4243
166	S	A	-1.0426
167	Y	A	0.0000
168	S	A	-0.9184
169	V	A	0.0000
170	T	A	-0.6448
171	S	A	0.0000
172	D	A	0.0000
173	W	A	0.0000
174	F	A	-0.1236
175	S	A	0.0000
176	P	A	-0.4298
177	T	A	-0.1297
178	G	A	-0.2320
179	C	A	0.0000
180	V	A	-0.6086
181	H	A	-1.1474
182	M	A	0.0000
183	S	A	-0.5318
184	N	A	0.0000
185	P	A	-0.6753
186	I	A	0.0000
187	V	A	-0.2153
188	P	A	-0.7175
189	S	A	-1.1031
190	D	A	-2.0924
191	Q	A	-1.4943
192	P	A	-1.3065
193	S	A	0.0000
194	Q	A	-0.3055
195	F	A	0.0000
196	T	A	-0.1978
197	L	A	0.0000
198	E	A	-1.0041
199	N	A	-0.7282
200	I	A	-0.2148
201	T	A	-0.2214
202	S	A	-0.0754
203	F	A	0.5382
204	E	A	-1.1530
205	G	A	-1.1803
206	L	A	-0.5878
207	Q	A	-1.1088
208	N	A	-0.7323
209	F	A	0.0000
210	T	A	0.0000
211	M	A	0.0000
212	T	A	0.0000
213	V	A	0.0000
214	V	A	0.0000
215	E	A	-0.7647
216	T	A	0.0000
217	D	A	-1.1347
218	Y	A	-0.6166
219	N	A	-1.3793
220	Q	A	-1.2972
221	F	A	-0.7745
222	S	A	0.0000
223	I	A	0.0000
224	V	A	0.0000
225	S	A	0.0000
226	F	A	0.2622
227	N	A	0.0000
228	M	A	-0.1716
229	T	A	-0.8713
230	L	A	-1.2968
231	K	A	-2.5131
232	N	A	-2.2017
233	R	A	-1.1456
234	V	A	0.0000
235	Y	A	0.3123
236	F	A	0.0000
237	E	A	0.0000
238	L	A	0.0000
239	I	A	0.0000
240	L	A	0.0000
241	Y	A	0.0000
242	G	A	0.0000
243	R	A	-1.5880
244	T	A	-1.8994
245	K	A	-2.3765
246	K	A	-2.2899
247	L	A	-1.0266
248	I	A	-0.1778
249	P	A	-1.2330
250	K	A	-2.4607
251	V	A	0.0000
252	K	A	-1.8212
253	D	A	-3.1576
254	H	A	-2.6318
255	Y	A	0.0000
256	H	A	-2.5262
257	K	A	-3.0977
258	L	A	-1.6244
259	A	A	0.0000
260	K	A	-2.4806
261	S	A	-1.6559
262	L	A	0.0000
263	D	A	-2.3488
264	I	A	0.0000
265	P	A	-1.2497
266	D	A	-1.8524
267	C	A	-0.5050
268	H	A	-0.4017
269	I	A	0.0000
270	I	A	0.0000
271	F	A	0.0711
272	T	A	-0.1913
273	D	A	0.0000
274	P	A	-0.5490
275	L	A	0.0000
276	G	A	-0.9023
277	K	A	-0.9954
278	D	A	0.0000
279	H	A	0.0000
280	L	A	-0.1748
281	E	A	-0.5284
282	W	A	0.8394
283	W	A	0.7553
284	S	A	0.0000
285	S	A	-0.5985
286	G	A	-0.5591
287	T	A	-0.5247
288	K	A	-1.5557
289	C	A	-0.7506
290	P	A	-1.0640
291	P	A	0.0000
292	R	A	-0.8152
293	Q	A	-1.2479
294	V	A	0.0000
295	F	A	-0.5090
296	S	A	-1.0871
297	Q	A	-1.7863
298	G	A	-1.0120
299	L	A	-0.5173
300	P	A	-0.7742
301	G	A	-1.2470