Project name: 4z5r:K

Chain sequence(s)	K: EVQLVESGGGLVQPGGSLRLSCATSGYTFTEYIIHWVRQAPGKGLEWVASINPDYDITNYNQRFKGRFTISLDKSKRTAYLQMNSLRAEDTAVYYCASWISDFFDYWGQGTLVTVSSASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.1022
• Maximal score value: 2.4187
• Average score: -0.5872
• Total score value: -125.0682

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	K	-2.0734
2	V	K	-1.2849
3	Q	K	-1.3084
4	L	K	0.0000
5	V	K	0.4268
6	E	K	0.0000
7	S	K	-0.4823
8	G	K	-0.8682
9	G	K	-0.4232
10	G	K	-0.2184
11	L	K	0.0593
12	V	K	-0.5832
13	Q	K	-1.5998
14	P	K	-1.8326
15	G	K	-1.6128
16	G	K	-1.2979
17	S	K	-1.6937
18	L	K	-1.3132
19	R	K	-2.3455
20	L	K	0.0000
21	S	K	-0.4690
22	C	K	0.0000
23	A	K	-0.5676
24	T	K	0.0000
25	S	K	-1.1302
26	G	K	-1.2329
27	Y	K	-0.7863
28	T	K	-0.6413
29	F	K	-1.4614
30	T	K	-1.4478
31	E	K	-1.5946
32	Y	K	-0.2603
33	I	K	0.5930
34	I	K	0.0000
35	H	K	0.0000
36	W	K	0.0000
37	V	K	0.0000
38	R	K	0.0000
39	Q	K	-0.3085
40	A	K	-1.0433
41	P	K	-0.9312
42	G	K	-1.4135
43	K	K	-2.0170
44	G	K	-0.8361
45	L	K	0.7623
46	E	K	0.2564
47	W	K	0.5382
48	V	K	0.0000
49	A	K	0.0000
50	S	K	0.0000
51	I	K	0.0000
52	N	K	-0.3290
52A	P	K	0.0000
53	D	K	-1.8764
54	Y	K	0.0289
55	D	K	-0.7966
56	I	K	0.6921
57	T	K	0.0665
58	N	K	-1.0030
59	Y	K	-1.5125
60	N	K	-1.9103
61	Q	K	-2.9677
62	R	K	-3.0819
63	F	K	0.0000
64	K	K	-3.1022
65	G	K	-2.1112
66	R	K	-1.8899
67	F	K	0.0000
68	T	K	-1.1977
69	I	K	0.0000
70	S	K	-0.3534
71	L	K	-1.1098
72	D	K	-2.1434
73	K	K	-2.9736
74	S	K	-2.2765
75	K	K	-3.0450
76	R	K	-2.8348
77	T	K	0.0000
78	A	K	0.0000
79	Y	K	-0.5325
80	L	K	0.0000
81	Q	K	-1.7764
82	M	K	0.0000
82A	N	K	-2.2757
82B	S	K	-1.6377
82C	L	K	0.0000
83	R	K	-2.4843
84	A	K	-1.7906
85	E	K	-2.2530
86	D	K	0.0000
87	T	K	-0.7354
88	A	K	0.0000
89	V	K	0.3551
90	Y	K	0.0000
91	Y	K	0.3740
92	C	K	0.0000
93	A	K	0.0000
94	S	K	0.0000
95	W	K	0.8474
96	I	K	1.4165
97	S	K	0.4169
98	D	K	-0.6332
99	F	K	1.2183
100	F	K	0.7415
101	D	K	-0.4439
102	Y	K	0.3081
103	W	K	0.1897
104	G	K	-0.2067
105	Q	K	-0.9471
106	G	K	0.0000
107	T	K	-0.0675
108	L	K	0.0582
109	V	K	0.0000
110	T	K	-0.4049
111	V	K	0.0000
112	S	K	-0.9384
113	S	K	-0.7058
114	A	K	-0.4534
115	S	K	-0.6042
116	T	K	-0.7214
117	K	K	-1.4634
118	G	K	-1.6692
119	P	K	0.0000
120	S	K	-0.1483
121	V	K	0.0000
122	F	K	1.1539
123	P	K	0.2524
124	L	K	0.6234
125	A	K	-0.4357
126	P	K	0.0000
127	S	K	-0.3334
128	S	K	-0.5167
133	G	K	-0.8653
134	G	K	-0.8577
135	T	K	-0.5972
136	A	K	-0.4027
137	A	K	0.1091
138	L	K	0.0000
139	G	K	0.0000
140	C	K	0.0000
141	L	K	0.7527
142	V	K	0.0000
143	K	K	-0.2748
144	D	K	-0.7988
145	Y	K	0.0000
146	F	K	0.0000
147	P	K	0.0000
148	E	K	-0.5916
149	P	K	-0.7482
150	V	K	-0.7677
151	T	K	-0.7096
152	V	K	-0.3337
153	S	K	-0.4299
154	W	K	0.0000
155	N	K	-0.7653
156	S	K	-0.6654
157	G	K	-0.5484
158	A	K	-0.2223
159	L	K	0.0135
160	T	K	-0.2820
161	S	K	-0.3700
162	G	K	-0.4740
163	V	K	-0.0411
164	H	K	-0.5448
165	T	K	0.0690
166	F	K	0.7499
167	P	K	0.6282
168	A	K	1.1945
169	V	K	2.4187
170	L	K	2.0034
171	Q	K	0.6026
172	S	K	0.0629
173	S	K	-0.2566
174	G	K	0.1732
175	L	K	0.1974
176	Y	K	0.7948
177	S	K	0.0000
178	L	K	0.0000
179	S	K	0.6104
180	S	K	0.0000
181	V	K	0.4260
182	V	K	0.0000
183	T	K	-0.2013
184	V	K	0.0000
185	P	K	-0.6191
186	S	K	-0.7242
187	S	K	-0.6483
188	S	K	-0.5796
189	L	K	-0.8324
190	G	K	-1.0925
191	T	K	-0.7006
192	Q	K	-1.1646
193	T	K	-1.0573
194	Y	K	0.0000
195	I	K	-1.3485
196	C	K	0.0000
197	N	K	-1.6734
198	V	K	0.0000
199	N	K	-2.2845
200	H	K	0.0000
201	K	K	-2.8634
202	P	K	-1.6505
203	S	K	-1.9249
204	N	K	-2.6605
205	T	K	-2.2366
206	K	K	-2.8580
207	V	K	-1.9313
208	D	K	-2.7310
209	K	K	-2.0007
210	K	K	-2.5013
211	V	K	0.0000
212	E	K	-2.4419
213	P	K	-1.2077