Project name: 3u0t:D
Status: done
submitted: 2019-03-20 19:58:02, status changed: 2019-03-20 20:06:27
Settings
|
Chain sequence(s)
|
D: QVQLVQSGAEVKKPGASVKVSCKASGYYTEAYYIHWVRQAPGQGLEWMGRIDPATGNTKYAPRLQDRVTMTRDTSTSTVYMELSSLRSEDTAVYYCASLYSLPVYWGQGTTVTVSSASTKGPSVFPLAPCSSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSQTYTCNVDHKPSNTKVDKTVER
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.0793
-
Maximal score value
-
2.4685
-
Average score
-
-0.4776
-
Total score value
-
-98.8664
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
D |
-0.9460 |
|
| 2 |
V |
D |
0.0000 |
|
| 3 |
Q |
D |
-1.2212 |
|
| 4 |
L |
D |
0.0000 |
|
| 5 |
V |
D |
0.7660 |
|
| 6 |
Q |
D |
0.0000 |
|
| 7 |
S |
D |
-0.5869 |
|
| 8 |
G |
D |
-0.6572 |
|
| 9 |
A |
D |
-0.4285 |
|
| 10 |
E |
D |
-1.0052 |
|
| 11 |
V |
D |
-0.3437 |
|
| 12 |
K |
D |
-1.5716 |
|
| 13 |
K |
D |
-2.4388 |
|
| 14 |
P |
D |
-2.1227 |
|
| 15 |
G |
D |
-1.6478 |
|
| 16 |
A |
D |
-1.2972 |
|
| 17 |
S |
D |
-1.3656 |
|
| 18 |
V |
D |
0.0000 |
|
| 19 |
K |
D |
-1.9827 |
|
| 20 |
V |
D |
0.0000 |
|
| 21 |
S |
D |
-0.5585 |
|
| 22 |
C |
D |
0.0000 |
|
| 23 |
K |
D |
-1.0864 |
|
| 24 |
A |
D |
0.0000 |
|
| 25 |
S |
D |
-0.6413 |
|
| 26 |
G |
D |
-0.3480 |
|
| 27 |
Y |
D |
1.0713 |
|
| 28 |
Y |
D |
1.1526 |
|
| 29 |
T |
D |
-0.2407 |
|
| 30 |
E |
D |
-0.9689 |
|
| 31 |
A |
D |
0.0428 |
|
| 32 |
Y |
D |
0.6457 |
|
| 33 |
Y |
D |
0.4801 |
|
| 34 |
I |
D |
0.0000 |
|
| 35 |
H |
D |
0.0000 |
|
| 36 |
W |
D |
0.0000 |
|
| 37 |
V |
D |
0.0000 |
|
| 38 |
R |
D |
0.0000 |
|
| 39 |
Q |
D |
-0.4246 |
|
| 40 |
A |
D |
-1.0532 |
|
| 41 |
P |
D |
-1.2430 |
|
| 42 |
G |
D |
-1.2022 |
|
| 43 |
Q |
D |
-1.7690 |
|
| 44 |
G |
D |
-0.6498 |
|
| 45 |
L |
D |
0.7492 |
|
| 46 |
E |
D |
0.1492 |
|
| 47 |
W |
D |
0.4406 |
|
| 48 |
M |
D |
0.0000 |
|
| 49 |
G |
D |
0.0000 |
|
| 50 |
R |
D |
-0.8192 |
|
| 51 |
I |
D |
0.0000 |
|
| 52 |
D |
D |
-1.1022 |
|
| 52A |
P |
D |
0.0000 |
|
| 53 |
A |
D |
-0.8634 |
|
| 54 |
T |
D |
-0.9322 |
|
| 55 |
G |
D |
-1.1746 |
|
| 56 |
N |
D |
-1.8327 |
|
| 57 |
T |
D |
-1.4512 |
|
| 58 |
K |
D |
-1.8850 |
|
| 59 |
Y |
D |
-1.4091 |
|
| 60 |
A |
D |
0.0000 |
|
| 61 |
P |
D |
-1.9060 |
|
| 62 |
R |
D |
-2.5217 |
|
| 63 |
L |
D |
0.0000 |
|
| 64 |
Q |
D |
-2.5540 |
|
| 65 |
D |
D |
-2.7415 |
|
| 66 |
R |
D |
-1.9091 |
|
| 67 |
V |
D |
0.0000 |
|
| 68 |
T |
D |
-0.9808 |
|
| 69 |
M |
D |
0.0000 |
|
| 70 |
T |
D |
-0.8276 |
|
| 71 |
R |
D |
-1.5145 |
|
| 72 |
D |
D |
-1.3394 |
|
| 73 |
T |
D |
-1.0585 |
|
| 74 |
S |
D |
-0.5960 |
|
| 75 |
T |
D |
-0.7993 |
|
| 76 |
S |
D |
-1.1504 |
|
| 77 |
T |
D |
0.0000 |
|
| 78 |
V |
D |
0.0000 |
|
| 79 |
Y |
D |
-0.6633 |
|
| 80 |
M |
D |
0.0000 |
|
| 81 |
E |
D |
-1.2498 |
|
| 82 |
L |
D |
0.0000 |
|
| 82A |
S |
D |
-1.2998 |
|
| 82B |
S |
D |
-1.4135 |
|
| 82C |
L |
D |
0.0000 |
|
| 83 |
R |
D |
-3.0793 |
|
| 84 |
S |
D |
-2.3939 |
|
| 85 |
E |
D |
-2.6518 |
|
| 86 |
D |
D |
0.0000 |
|
| 87 |
T |
D |
-1.0786 |
|
| 88 |
A |
D |
0.0000 |
|
| 89 |
V |
D |
0.3917 |
|
| 90 |
Y |
D |
0.0000 |
|
| 91 |
Y |
D |
0.4092 |
|
| 92 |
C |
D |
0.0000 |
|
| 93 |
A |
D |
0.0000 |
|
| 94 |
S |
D |
0.0000 |
|
| 95 |
L |
D |
1.7803 |
|
| 96 |
Y |
D |
2.1691 |
|
| 97 |
S |
D |
1.8171 |
|
| 98 |
L |
D |
1.8223 |
|
| 99 |
P |
D |
1.2090 |
|
| 100 |
V |
D |
1.7207 |
|
| 101 |
Y |
D |
0.6599 |
|
| 102 |
W |
D |
0.7838 |
|
| 103 |
G |
D |
0.0000 |
|
| 104 |
Q |
D |
-0.6764 |
|
| 105 |
G |
D |
-0.1666 |
|
| 106 |
T |
D |
0.0000 |
|
| 107 |
T |
D |
-0.1500 |
|
| 108 |
V |
D |
0.0000 |
|
| 109 |
T |
D |
0.0000 |
|
| 110 |
V |
D |
0.0000 |
|
| 111 |
S |
D |
-1.2063 |
|
| 112 |
S |
D |
-0.9535 |
|
| 113 |
A |
D |
-0.5995 |
|
| 114 |
S |
D |
-0.5745 |
|
| 115 |
T |
D |
-0.6479 |
|
| 116 |
K |
D |
-1.2145 |
|
| 117 |
G |
D |
-1.4472 |
|
| 118 |
P |
D |
0.0000 |
|
| 119 |
S |
D |
-0.1041 |
|
| 120 |
V |
D |
0.0000 |
|
| 121 |
F |
D |
0.9460 |
|
| 122 |
P |
D |
0.2588 |
|
| 123 |
L |
D |
0.6079 |
|
| 124 |
A |
D |
-0.3312 |
|
| 125 |
P |
D |
-0.2818 |
|
| 126 |
C |
D |
0.4036 |
|
| 127 |
S |
D |
-0.1686 |
|
| 133 |
S |
D |
-0.3921 |
|
| 134 |
T |
D |
-0.3346 |
|
| 135 |
A |
D |
-0.4790 |
|
| 136 |
A |
D |
-0.1256 |
|
| 137 |
L |
D |
0.0000 |
|
| 138 |
G |
D |
0.0000 |
|
| 139 |
C |
D |
0.0000 |
|
| 140 |
L |
D |
0.6324 |
|
| 141 |
V |
D |
0.0000 |
|
| 142 |
K |
D |
-0.2329 |
|
| 143 |
D |
D |
-0.6281 |
|
| 144 |
Y |
D |
0.0000 |
|
| 145 |
F |
D |
0.0000 |
|
| 146 |
P |
D |
-0.7266 |
|
| 147 |
E |
D |
-0.9673 |
|
| 148 |
P |
D |
-1.0279 |
|
| 149 |
V |
D |
-0.8387 |
|
| 150 |
T |
D |
-0.6367 |
|
| 151 |
V |
D |
-0.2670 |
|
| 152 |
S |
D |
-0.5775 |
|
| 153 |
W |
D |
0.0000 |
|
| 154 |
N |
D |
-0.8448 |
|
| 155 |
S |
D |
-0.7912 |
|
| 156 |
G |
D |
-0.5630 |
|
| 157 |
A |
D |
-0.2371 |
|
| 158 |
L |
D |
-0.0678 |
|
| 159 |
T |
D |
-0.2770 |
|
| 160 |
S |
D |
-0.3521 |
|
| 161 |
G |
D |
-0.4325 |
|
| 162 |
V |
D |
0.0465 |
|
| 163 |
H |
D |
-0.4247 |
|
| 164 |
T |
D |
0.1662 |
|
| 165 |
F |
D |
0.8983 |
|
| 166 |
P |
D |
0.6605 |
|
| 167 |
A |
D |
1.1333 |
|
| 168 |
V |
D |
2.4685 |
|
| 169 |
L |
D |
2.0750 |
|
| 170 |
Q |
D |
0.6870 |
|
| 171 |
S |
D |
0.0894 |
|
| 172 |
S |
D |
-0.2104 |
|
| 173 |
G |
D |
0.2237 |
|
| 174 |
L |
D |
0.1599 |
|
| 175 |
Y |
D |
0.0000 |
|
| 176 |
S |
D |
0.0000 |
|
| 177 |
L |
D |
0.0000 |
|
| 178 |
S |
D |
0.6151 |
|
| 179 |
S |
D |
0.0000 |
|
| 180 |
V |
D |
0.4819 |
|
| 181 |
V |
D |
0.0000 |
|
| 182 |
T |
D |
-0.2075 |
|
| 183 |
V |
D |
0.0000 |
|
| 184 |
P |
D |
-0.6495 |
|
| 185 |
S |
D |
-0.9562 |
|
| 186 |
S |
D |
-0.6130 |
|
| 192 |
Q |
D |
-1.9344 |
|
| 193 |
T |
D |
-1.3899 |
|
| 194 |
Y |
D |
0.0000 |
|
| 195 |
T |
D |
-1.0823 |
|
| 196 |
C |
D |
0.0000 |
|
| 197 |
N |
D |
-1.5500 |
|
| 198 |
V |
D |
0.0000 |
|
| 199 |
D |
D |
-1.9532 |
|
| 200 |
H |
D |
0.0000 |
|
| 201 |
K |
D |
-2.8462 |
|
| 202 |
P |
D |
-1.7796 |
|
| 203 |
S |
D |
-1.8596 |
|
| 204 |
N |
D |
-2.6340 |
|
| 205 |
T |
D |
-2.1018 |
|
| 206 |
K |
D |
-2.7160 |
|
| 207 |
V |
D |
-1.5537 |
|
| 208 |
D |
D |
-2.3425 |
|
| 209 |
K |
D |
-1.5379 |
|
| 210 |
T |
D |
-1.1118 |
|
| 211 |
V |
D |
0.0000 |
|
| 212 |
E |
D |
-2.9743 |
|
| 213 |
R |
D |
-2.9318 |
|