Project name: 2osl:H
Status: done
submitted: 2019-03-20 15:28:15, status changed: 2019-03-20 17:12:09
Settings
|
Chain sequence(s)
|
H: QVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.9831
-
Maximal score value
-
2.4113
-
Average score
-
-0.5452
-
Total score value
-
-122.133
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
H |
-1.1498 |
|
| 2 |
V |
H |
-0.1820 |
|
| 3 |
Q |
H |
-1.1539 |
|
| 4 |
L |
H |
0.0000 |
|
| 5 |
Q |
H |
-1.7077 |
|
| 6 |
Q |
H |
0.0000 |
|
| 7 |
P |
H |
-0.8118 |
|
| 8 |
G |
H |
-0.7950 |
|
| 9 |
A |
H |
-0.8190 |
|
| 10 |
E |
H |
-0.9887 |
|
| 11 |
L |
H |
-0.4233 |
|
| 12 |
V |
H |
0.0000 |
|
| 13 |
K |
H |
-1.8580 |
|
| 14 |
P |
H |
-1.2348 |
|
| 15 |
G |
H |
-1.1443 |
|
| 16 |
A |
H |
-0.9512 |
|
| 17 |
S |
H |
-1.1586 |
|
| 18 |
V |
H |
0.0000 |
|
| 19 |
K |
H |
-2.0276 |
|
| 20 |
M |
H |
0.0000 |
|
| 21 |
S |
H |
-0.8111 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
K |
H |
-1.5105 |
|
| 24 |
A |
H |
0.0000 |
|
| 25 |
S |
H |
-0.9959 |
|
| 26 |
G |
H |
-0.6798 |
|
| 27 |
Y |
H |
-0.1716 |
|
| 28 |
T |
H |
-0.2060 |
|
| 29 |
F |
H |
0.0000 |
|
| 30 |
T |
H |
-0.7277 |
|
| 31 |
S |
H |
-0.1734 |
|
| 32 |
Y |
H |
0.3544 |
|
| 33 |
N |
H |
-0.3088 |
|
| 34 |
M |
H |
0.0000 |
|
| 35 |
H |
H |
0.0942 |
|
| 36 |
W |
H |
0.0000 |
|
| 37 |
V |
H |
0.0000 |
|
| 38 |
K |
H |
-0.1454 |
|
| 39 |
Q |
H |
-0.4042 |
|
| 40 |
T |
H |
-1.0718 |
|
| 41 |
P |
H |
-0.8909 |
|
| 42 |
G |
H |
-1.4364 |
|
| 43 |
R |
H |
-2.1146 |
|
| 44 |
G |
H |
-0.8500 |
|
| 45 |
L |
H |
0.5896 |
|
| 46 |
E |
H |
-0.4629 |
|
| 47 |
W |
H |
0.0606 |
|
| 48 |
I |
H |
0.0000 |
|
| 49 |
G |
H |
0.0000 |
|
| 50 |
A |
H |
0.0000 |
|
| 51 |
I |
H |
0.0000 |
|
| 52 |
Y |
H |
-0.7967 |
|
| 53 |
P |
H |
0.0000 |
|
| 54 |
G |
H |
-1.5011 |
|
| 55 |
N |
H |
-2.1185 |
|
| 56 |
G |
H |
-2.1969 |
|
| 57 |
D |
H |
-2.4321 |
|
| 58 |
T |
H |
-1.1574 |
|
| 59 |
S |
H |
-0.7526 |
|
| 60 |
Y |
H |
-0.9657 |
|
| 61 |
N |
H |
-1.7920 |
|
| 62 |
Q |
H |
-2.8099 |
|
| 63 |
K |
H |
-2.9831 |
|
| 64 |
F |
H |
0.0000 |
|
| 65 |
K |
H |
-2.9602 |
|
| 66 |
G |
H |
-1.9650 |
|
| 67 |
K |
H |
-1.6644 |
|
| 68 |
A |
H |
0.0000 |
|
| 69 |
T |
H |
-0.8708 |
|
| 70 |
L |
H |
0.0000 |
|
| 71 |
T |
H |
-0.7025 |
|
| 72 |
A |
H |
-1.3417 |
|
| 73 |
D |
H |
-1.9910 |
|
| 74 |
K |
H |
-2.4075 |
|
| 75 |
S |
H |
-1.3985 |
|
| 76 |
S |
H |
-1.2615 |
|
| 77 |
S |
H |
-1.3557 |
|
| 78 |
T |
H |
0.0000 |
|
| 79 |
A |
H |
0.0000 |
|
| 80 |
Y |
H |
-0.5424 |
|
| 81 |
M |
H |
0.0000 |
|
| 82 |
Q |
H |
-1.3932 |
|
| 83 |
L |
H |
0.0000 |
|
| 84 |
S |
H |
-0.9084 |
|
| 85 |
S |
H |
-0.8664 |
|
| 86 |
L |
H |
0.0000 |
|
| 87 |
T |
H |
-1.2305 |
|
| 88 |
S |
H |
-1.3981 |
|
| 89 |
E |
H |
-1.9613 |
|
| 90 |
D |
H |
0.0000 |
|
| 91 |
S |
H |
-0.7667 |
|
| 92 |
A |
H |
-0.3820 |
|
| 93 |
V |
H |
0.3012 |
|
| 94 |
Y |
H |
0.0000 |
|
| 95 |
Y |
H |
0.5091 |
|
| 96 |
C |
H |
0.0000 |
|
| 97 |
A |
H |
0.0000 |
|
| 98 |
R |
H |
0.0756 |
|
| 99 |
S |
H |
0.0000 |
|
| 100 |
T |
H |
0.0000 |
|
| 101 |
Y |
H |
1.8596 |
|
| 102 |
Y |
H |
1.5379 |
|
| 103 |
G |
H |
0.1215 |
|
| 104 |
G |
H |
-0.5620 |
|
| 105 |
D |
H |
-0.4753 |
|
| 106 |
W |
H |
1.5071 |
|
| 107 |
Y |
H |
1.5056 |
|
| 108 |
F |
H |
0.7507 |
|
| 109 |
N |
H |
-0.1679 |
|
| 110 |
V |
H |
0.1034 |
|
| 111 |
W |
H |
0.2562 |
|
| 112 |
G |
H |
0.0000 |
|
| 113 |
A |
H |
-0.1566 |
|
| 114 |
G |
H |
-0.1036 |
|
| 115 |
T |
H |
0.0000 |
|
| 116 |
T |
H |
-0.2686 |
|
| 117 |
V |
H |
0.0000 |
|
| 118 |
T |
H |
-0.6235 |
|
| 119 |
V |
H |
0.0000 |
|
| 120 |
S |
H |
-0.6554 |
|
| 121 |
A |
H |
-0.6107 |
|
| 122 |
A |
H |
-0.4316 |
|
| 123 |
S |
H |
-0.6661 |
|
| 124 |
T |
H |
-0.8263 |
|
| 125 |
K |
H |
-1.3970 |
|
| 126 |
G |
H |
-1.4600 |
|
| 127 |
P |
H |
0.0000 |
|
| 128 |
S |
H |
-0.0499 |
|
| 129 |
V |
H |
0.0000 |
|
| 130 |
F |
H |
0.9942 |
|
| 131 |
P |
H |
0.0077 |
|
| 132 |
L |
H |
0.4234 |
|
| 133 |
A |
H |
-0.7982 |
|
| 134 |
P |
H |
0.0000 |
|
| 135 |
S |
H |
-1.3312 |
|
| 136 |
S |
H |
-1.3638 |
|
| 137 |
K |
H |
-2.0478 |
|
| 138 |
S |
H |
-1.1254 |
|
| 139 |
T |
H |
-1.1068 |
|
| 140 |
S |
H |
-1.0461 |
|
| 141 |
G |
H |
-1.1857 |
|
| 142 |
G |
H |
-0.9076 |
|
| 143 |
T |
H |
-0.6098 |
|
| 144 |
A |
H |
-0.5529 |
|
| 145 |
A |
H |
0.1346 |
|
| 146 |
L |
H |
0.0000 |
|
| 147 |
G |
H |
0.0000 |
|
| 148 |
C |
H |
0.0000 |
|
| 149 |
L |
H |
0.8288 |
|
| 150 |
V |
H |
0.0000 |
|
| 151 |
K |
H |
0.1189 |
|
| 152 |
D |
H |
-0.4043 |
|
| 153 |
Y |
H |
0.0000 |
|
| 154 |
F |
H |
0.0000 |
|
| 155 |
P |
H |
0.0000 |
|
| 156 |
E |
H |
-0.3718 |
|
| 157 |
P |
H |
-0.8298 |
|
| 158 |
V |
H |
-0.6797 |
|
| 159 |
T |
H |
-0.5794 |
|
| 160 |
V |
H |
-0.1457 |
|
| 161 |
S |
H |
-0.2323 |
|
| 162 |
W |
H |
0.0000 |
|
| 163 |
N |
H |
-0.6880 |
|
| 164 |
S |
H |
-0.5769 |
|
| 165 |
G |
H |
-0.5072 |
|
| 166 |
A |
H |
-0.2400 |
|
| 167 |
L |
H |
-0.0136 |
|
| 168 |
T |
H |
-0.3094 |
|
| 169 |
S |
H |
-0.3811 |
|
| 170 |
G |
H |
-0.4711 |
|
| 171 |
V |
H |
-0.0042 |
|
| 172 |
H |
H |
-0.5162 |
|
| 173 |
T |
H |
0.1578 |
|
| 174 |
F |
H |
0.9423 |
|
| 175 |
P |
H |
0.7130 |
|
| 176 |
A |
H |
1.2665 |
|
| 177 |
V |
H |
2.4113 |
|
| 178 |
L |
H |
2.0585 |
|
| 179 |
Q |
H |
0.6743 |
|
| 180 |
S |
H |
0.0666 |
|
| 181 |
S |
H |
-0.2427 |
|
| 182 |
G |
H |
0.1890 |
|
| 183 |
L |
H |
0.3034 |
|
| 184 |
Y |
H |
0.8183 |
|
| 185 |
S |
H |
0.7934 |
|
| 186 |
L |
H |
0.0000 |
|
| 187 |
S |
H |
0.6763 |
|
| 188 |
S |
H |
0.0000 |
|
| 189 |
V |
H |
0.4610 |
|
| 190 |
V |
H |
0.0000 |
|
| 191 |
T |
H |
-0.2059 |
|
| 192 |
V |
H |
0.0000 |
|
| 193 |
P |
H |
-0.5325 |
|
| 194 |
S |
H |
-0.6214 |
|
| 195 |
S |
H |
-0.6399 |
|
| 196 |
S |
H |
-0.6064 |
|
| 197 |
L |
H |
-0.8514 |
|
| 198 |
G |
H |
-0.9330 |
|
| 199 |
T |
H |
-0.7581 |
|
| 200 |
Q |
H |
-1.0800 |
|
| 201 |
T |
H |
-1.1049 |
|
| 202 |
Y |
H |
0.0000 |
|
| 203 |
I |
H |
-1.1893 |
|
| 204 |
C |
H |
0.0000 |
|
| 205 |
N |
H |
-1.3302 |
|
| 206 |
V |
H |
0.0000 |
|
| 207 |
N |
H |
-1.7535 |
|
| 208 |
H |
H |
0.0000 |
|
| 209 |
K |
H |
-2.7071 |
|
| 210 |
P |
H |
-1.6727 |
|
| 211 |
S |
H |
-1.8763 |
|
| 212 |
N |
H |
-2.5597 |
|
| 213 |
T |
H |
-2.0889 |
|
| 214 |
K |
H |
-2.6100 |
|
| 215 |
V |
H |
-1.4704 |
|
| 216 |
D |
H |
-2.1718 |
|
| 217 |
K |
H |
-2.1411 |
|
| 218 |
K |
H |
-2.4882 |
|
| 219 |
V |
H |
0.0000 |
|
| 220 |
E |
H |
-2.7479 |
|
| 221 |
P |
H |
-1.8967 |
|
| 222 |
K |
H |
-2.2037 |
|
| 223 |
S |
H |
-1.1577 |
|
| 224 |
C |
H |
-0.4366 |
|