| Chain sequence(s) |
A: GPLGSLTASSMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESSLRSSKVDEAVAVLQA C: WPPEFHPGVPWKGLQ B: GPLGSLTASSMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSSELLHMLESPESSLRSKKVDEAVAVLQAHQ D: WPPEFHPGVPWKKGLQ |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 540 | G | A | -0.2768 | |
| 541 | P | A | 0.1021 | |
| 542 | L | A | 0.9797 | |
| 543 | G | A | 0.0778 | |
| 544 | S | A | -0.0241 | |
| 545 | L | A | 0.0415 | |
| 546 | T | A | 0.0271 | |
| 547 | A | A | -0.0765 | |
| 548 | S | A | -0.0047 | |
| 549 | M | A | 0.2857 | |
| 550 | L | A | 0.0000 | |
| 551 | A | A | -0.2394 | |
| 552 | S | A | -0.3046 | |
| 553 | A | A | -0.6338 | |
| 554 | P | A | -1.1129 | |
| 555 | P | A | -1.2705 | |
| 556 | Q | A | -2.0088 | |
| 557 | E | A | -1.9079 | |
| 558 | Q | A | -1.0858 | |
| 559 | K | A | -1.2694 | |
| 560 | Q | A | -1.3480 | |
| 561 | M | A | -0.3965 | |
| 562 | L | A | 0.0000 | |
| 563 | G | A | 0.0000 | |
| 564 | E | A | -0.3089 | |
| 565 | R | A | 0.0182 | |
| 566 | L | A | 0.0000 | |
| 567 | F | A | 0.0000 | |
| 568 | P | A | -0.1663 | |
| 569 | L | A | 0.2653 | |
| 570 | I | A | 0.0000 | |
| 571 | Q | A | -0.5981 | |
| 572 | A | A | -0.1240 | |
| 573 | M | A | -0.4630 | |
| 574 | H | A | -0.4251 | |
| 575 | P | A | -0.5352 | |
| 576 | T | A | -0.3076 | |
| 577 | L | A | -0.2751 | |
| 578 | A | A | 0.0000 | |
| 579 | G | A | -1.3089 | |
| 580 | K | A | -0.9368 | |
| 581 | I | A | 0.0000 | |
| 582 | T | A | 0.0000 | |
| 583 | G | A | 0.0000 | |
| 584 | M | A | 0.0000 | |
| 585 | L | A | 0.0000 | |
| 586 | L | A | 0.0000 | |
| 587 | E | A | 0.0000 | |
| 588 | I | A | 0.0000 | |
| 589 | D | A | -2.1462 | |
| 590 | N | A | -1.5180 | |
| 591 | S | A | -1.3807 | |
| 592 | E | A | -2.0631 | |
| 593 | L | A | 0.0000 | |
| 594 | L | A | 0.0000 | |
| 595 | H | A | -1.8372 | |
| 596 | M | A | 0.0000 | |
| 597 | L | A | -1.2144 | |
| 598 | E | A | -2.3707 | |
| 599 | S | A | -2.0336 | |
| 600 | P | A | -2.0928 | |
| 601 | E | A | -2.8972 | |
| 602 | S | A | -2.2397 | |
| 603 | L | A | 0.0000 | |
| 604 | R | A | -3.3192 | |
| 605 | S | A | -2.7527 | |
| 606 | K | A | -2.3709 | |
| 607 | V | A | 0.0000 | |
| 608 | D | A | -3.0993 | |
| 609 | E | A | -3.0178 | |
| 610 | A | A | 0.0000 | |
| 611 | V | A | -1.2281 | |
| 612 | A | A | -1.3922 | |
| 613 | V | A | -0.8450 | |
| 614 | L | A | -0.6146 | |
| 615 | Q | A | -1.1208 | |
| 616 | A | A | -0.8718 | |
| 540 | G | B | -0.2817 | |
| 541 | P | B | 0.1042 | |
| 542 | L | B | 0.9645 | |
| 543 | G | B | 0.0463 | |
| 544 | S | B | -0.1040 | |
| 545 | L | B | 0.0000 | |
| 546 | T | B | -0.2405 | |
| 547 | A | B | -0.1115 | |
| 548 | S | B | -0.0212 | |
| 549 | M | B | 0.2543 | |
| 550 | L | B | 0.0000 | |
| 551 | A | B | -0.2144 | |
| 552 | S | B | -0.2973 | |
| 553 | A | B | -0.5719 | |
| 554 | P | B | -1.0347 | |
| 555 | P | B | -1.4836 | |
| 556 | Q | B | -2.0275 | |
| 557 | E | B | -1.8792 | |
| 558 | Q | B | -1.0057 | |
| 559 | K | B | 0.0000 | |
| 560 | Q | B | -1.2738 | |
| 561 | M | B | -0.3804 | |
| 562 | L | B | 0.0000 | |
| 563 | G | B | 0.0000 | |
| 564 | E | B | -0.1817 | |
| 565 | R | B | 0.0516 | |
| 566 | L | B | 0.0000 | |
| 567 | F | B | -0.2803 | |
| 568 | P | B | -0.0279 | |
| 569 | L | B | 0.4219 | |
| 570 | I | B | 0.0000 | |
| 571 | Q | B | -0.4553 | |
| 572 | A | B | 0.0658 | |
| 573 | M | B | -0.1778 | |
| 574 | H | B | -0.5369 | |
| 575 | P | B | -0.4712 | |
| 576 | T | B | -0.4804 | |
| 577 | L | B | 0.0000 | |
| 578 | A | B | 0.0000 | |
| 579 | G | B | -1.6925 | |
| 580 | K | B | -1.6103 | |
| 581 | I | B | 0.0000 | |
| 582 | T | B | 0.0000 | |
| 583 | G | B | 0.0000 | |
| 584 | M | B | 0.0000 | |
| 585 | L | B | 0.0000 | |
| 586 | L | B | 0.0000 | |
| 587 | E | B | 0.0000 | |
| 588 | I | B | 0.0000 | |
| 589 | D | B | -0.9038 | |
| 590 | N | B | -0.7844 | |
| 591 | S | B | -0.9444 | |
| 592 | E | B | -1.2599 | |
| 593 | L | B | 0.0000 | |
| 594 | L | B | 0.0000 | |
| 595 | H | B | -1.9227 | |
| 596 | M | B | 0.0000 | |
| 597 | L | B | -1.1888 | |
| 598 | E | B | -2.3948 | |
| 599 | S | B | -2.0762 | |
| 600 | P | B | -1.9874 | |
| 601 | E | B | -2.7751 | |
| 602 | S | B | -2.0836 | |
| 603 | L | B | 0.0000 | |
| 604 | R | B | -2.8589 | |
| 605 | S | B | -2.3095 | |
| 606 | K | B | -1.7915 | |
| 607 | V | B | 0.0000 | |
| 608 | D | B | -2.4649 | |
| 609 | E | B | -1.6677 | |
| 610 | A | B | 0.0000 | |
| 611 | V | B | -1.0383 | |
| 612 | A | B | -0.9855 | |
| 613 | V | B | -0.6308 | |
| 614 | L | B | 0.0000 | |
| 615 | Q | B | -1.7760 | |
| 616 | A | B | -1.2005 | |
| 617 | H | B | -1.8065 | |
| 618 | Q | B | -2.0283 | |
| 1385 | W | C | -0.2525 | |
| 1386 | P | C | 0.0000 | |
| 1387 | P | C | -1.4181 | |
| 1388 | E | C | -2.4265 | |
| 1389 | F | C | 0.0000 | |
| 1390 | H | C | -1.7245 | |
| 1391 | P | C | -0.8177 | |
| 1392 | G | C | -0.5901 | |
| 1393 | V | C | -0.3374 | |
| 1394 | P | C | -1.1488 | |
| 1395 | W | C | 0.0000 | |
| 1396 | K | C | -2.4147 | |
| 1397 | G | C | -1.5012 | |
| 1398 | L | C | -1.2562 | |
| 1399 | Q | C | -1.9967 | |
| 1385 | W | D | 0.7673 | |
| 1386 | P | D | -0.2739 | |
| 1387 | P | D | -1.4380 | |
| 1388 | E | D | -2.6046 | |
| 1389 | F | D | 0.0000 | |
| 1390 | H | D | -1.6272 | |
| 1391 | P | D | -0.8113 | |
| 1392 | G | D | -0.3448 | |
| 1393 | V | D | 0.1925 | |
| 1394 | P | D | -0.9098 | |
| 1395 | W | D | 0.0000 | |
| 1396 | K | D | -2.4365 | |
| 1397 | G | D | 0.0000 | |
| 1398 | L | D | 0.0000 | |
| 1399 | Q | D | -2.1210 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine