Project name: CH2 A3D

Chain sequence(s)	A: GGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTTVLLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQ
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5601
• Maximal score value: 1.8292
• Average score: -1.0512
• Total score value: -112.479

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
236	G	A	-0.8043
237	G	A	-0.8531
238	P	A	0.0000
239	S	A	-0.2533
240	V	A	0.0000
241	F	A	1.1104
242	L	A	0.0000
243	F	A	1.0750
244	P	A	-0.5959
245	P	A	0.0000
246	K	A	-2.3527
247	P	A	-1.5842
248	K	A	-1.6832
249	D	A	0.0000
250	T	A	0.0000
251	L	A	1.0917
252	M	A	1.1481
253	I	A	1.8292
254	S	A	0.2785
255	R	A	-1.3344
256	T	A	-0.7310
257	P	A	0.0000
258	E	A	-0.9992
259	V	A	0.0000
260	T	A	0.3228
261	C	A	0.0000
262	V	A	0.0000
263	V	A	0.0000
264	V	A	-0.4893
265	D	A	-1.4950
266	V	A	0.0000
267	S	A	-2.1486
268	H	A	-2.2440
269	E	A	-2.8771
270	D	A	-2.6255
271	P	A	-2.4475
272	E	A	-3.0494
273	V	A	-1.9472
274	K	A	-2.2471
275	F	A	-1.2838
276	N	A	-1.4551
277	W	A	0.0000
278	Y	A	-0.9805
279	V	A	-1.0693
280	D	A	-2.1512
281	G	A	-1.0115
282	V	A	0.2680
283	E	A	-1.3198
284	V	A	-0.7016
285	H	A	-1.7742
286	N	A	-1.6726
287	A	A	-1.5982
288	K	A	-2.3104
289	T	A	-1.9864
290	K	A	-2.6106
291	P	A	-2.4444
292	R	A	-3.4044
293	E	A	-3.5601
294	E	A	-3.0305
295	Q	A	-1.6852
296	Y	A	0.1405
297	N	A	-0.7855
298	S	A	-1.1881
299	T	A	-1.8562
300	Y	A	-2.3893
301	R	A	-2.3496
302	V	A	0.0000
303	V	A	0.0000
304	S	A	0.0000
305	V	A	-0.7611
306	L	A	0.0000
307	T	A	-0.4621
308	V	A	0.0000
309	L	A	1.0261
310	H	A	0.5131
311	Q	A	-0.5174
312	D	A	-1.3162
313	W	A	0.0000
314	L	A	-0.5416
315	N	A	-1.8789
316	G	A	-2.3802
317	K	A	-2.4488
318	E	A	-2.8381
319	Y	A	0.0000
320	K	A	-1.8034
321	C	A	0.0000
322	K	A	-1.7472
323	V	A	0.0000
324	S	A	-1.5104
325	N	A	0.0000
326	K	A	-2.5644
327	A	A	-1.4103
328	L	A	-0.6456
329	P	A	-0.4383
330	A	A	-0.4354
331	P	A	-0.9743
332	I	A	-0.6638
333	E	A	-1.9986
334	K	A	-1.3795
335	T	A	-1.5778
336	I	A	0.0000
337	S	A	-2.4882
338	K	A	-2.8639
339	A	A	-2.0076
340	K	A	-2.6838
341	G	A	-2.0707
342	Q	A	-1.4943