Project name: 3J9T chain E1

Chain sequence(s)	K: LTPNQVNDELNKMQAFIRKEAEEKAKEIQLKADQEYEIEKTNIVRNETNNIDGNFKSKLKKAMLSQQITKSTIANKMRLKVLSAREQSLDGIFEETKEKLSGIANNRDEYKPILQSLIVEALLKLLEPKAIVKALERDVDLIESMKDDIMREYGEKAQRAPLEEIVISNDYLNKDLVSGGVVVSNASDKIEINNTLEERLKLLSEEALPAIRLELYG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -5.5848
• Maximal score value: 1.2005
• Average score: -1.6662
• Total score value: -361.559

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
8	L	K	1.2005
9	T	K	-0.1345
10	P	K	-1.3713
11	N	K	-2.5291
12	Q	K	-2.4293
13	V	K	-1.5500
14	N	K	-3.2938
15	D	K	-4.0613
16	E	K	-3.4929
17	L	K	-1.7100
18	N	K	-2.4563
19	K	K	-2.0338
20	M	K	-0.4216
21	Q	K	-0.9065
22	A	K	-1.0316
23	F	K	0.2638
24	I	K	0.0600
25	R	K	-2.8760
26	K	K	-3.8576
27	E	K	-4.0668
28	A	K	-3.9000
29	E	K	-4.9940
30	E	K	-5.5848
31	K	K	-4.7509
32	A	K	-3.3147
33	K	K	-3.8416
34	E	K	-3.4937
35	I	K	-1.2793
36	Q	K	-2.6908
37	L	K	-2.3787
38	K	K	-3.1148
39	A	K	-2.6628
40	D	K	-3.4686
41	Q	K	-3.7105
42	E	K	-3.5472
43	Y	K	-2.1239
44	E	K	-2.6613
45	I	K	-1.0764
46	E	K	-2.3787
47	K	K	-1.9533
48	T	K	-1.1952
49	N	K	-1.1778
50	I	K	-0.0468
51	V	K	-0.7370
52	R	K	-2.4565
53	N	K	-2.6364
54	E	K	-2.5546
55	T	K	-2.0006
56	N	K	-3.3122
57	N	K	-2.6453
58	I	K	-0.8214
59	D	K	-2.4940
60	G	K	-2.2846
61	N	K	-1.9367
62	F	K	-0.6381
63	K	K	-2.3321
64	S	K	-2.6089
65	K	K	-2.7494
66	L	K	-1.4921
67	K	K	-2.5627
68	K	K	-2.7527
69	A	K	-1.4642
70	M	K	-0.7729
71	L	K	-0.7972
72	S	K	-0.6676
73	Q	K	-1.5469
74	Q	K	-1.0814
75	I	K	0.8982
76	T	K	-0.4339
77	K	K	-1.7862
78	S	K	-0.9044
79	T	K	-0.6419
80	I	K	-0.4346
81	A	K	-1.1855
82	N	K	-2.2867
83	K	K	-2.0742
84	M	K	-0.8515
85	R	K	-1.5788
86	L	K	-0.4437
87	K	K	-1.3820
88	V	K	-0.1510
89	L	K	-0.3050
90	S	K	-1.1753
91	A	K	-1.3797
92	R	K	-2.1001
93	E	K	-3.1452
94	Q	K	-3.0094
95	S	K	-2.1604
96	L	K	0.0000
97	D	K	-3.4626
98	G	K	-2.4703
99	I	K	-1.1635
100	F	K	0.0000
101	E	K	-3.8196
102	E	K	-3.7371
103	T	K	-2.8573
104	K	K	-3.2467
105	E	K	-3.9586
106	K	K	-3.3846
107	L	K	-1.8385
108	S	K	-1.6051
109	G	K	-2.0676
110	I	K	-1.9050
111	A	K	0.0000
112	N	K	-2.1941
113	N	K	-3.2702
114	R	K	-4.0717
115	D	K	-4.0073
116	E	K	-3.7366
117	Y	K	0.0000
118	K	K	-2.2060
119	P	K	-1.2214
120	I	K	-0.2656
121	L	K	0.0000
122	Q	K	-0.8580
123	S	K	-0.6341
124	L	K	-0.4833
125	I	K	0.0000
126	V	K	0.0000
127	E	K	-1.9175
128	A	K	0.0000
129	L	K	0.0000
130	L	K	-0.5033
131	K	K	-1.2009
132	L	K	-0.0034
133	L	K	0.8960
134	E	K	-0.2862
135	P	K	-1.2824
136	K	K	-1.7835
137	A	K	0.0000
138	I	K	-0.4851
139	V	K	0.0000
140	K	K	-0.8463
141	A	K	0.0000
142	L	K	0.0000
143	E	K	-3.3045
144	R	K	-2.8204
145	D	K	0.0000
146	V	K	-2.0601
147	D	K	-2.9088
148	L	K	0.0000
149	I	K	0.0000
150	E	K	-2.6676
151	S	K	-2.0557
152	M	K	-2.0820
153	K	K	-2.8007
154	D	K	-4.0908
155	D	K	-3.7278
156	I	K	0.0000
157	M	K	-3.2114
158	R	K	-4.3772
159	E	K	-3.6891
160	Y	K	0.0000
161	G	K	-3.0841
162	E	K	-3.8437
163	K	K	-3.5724
164	A	K	-2.3219
165	Q	K	-2.3994
166	R	K	-2.0265
167	A	K	-1.8134
168	P	K	-2.8392
169	L	K	0.0000
170	E	K	-3.2066
171	E	K	-2.7443
172	I	K	0.0000
173	V	K	-0.5473
174	I	K	-0.5123
175	S	K	0.0000
176	N	K	-2.0312
177	D	K	-2.3728
178	Y	K	-1.3182
179	L	K	-1.2623
180	N	K	-2.2936
181	K	K	-2.8067
182	D	K	-2.2361
183	L	K	-0.3459
184	V	K	0.0000
185	S	K	-1.2875
186	G	K	0.0000
187	G	K	0.0000
188	V	K	0.0000
189	V	K	0.0000
190	V	K	0.0000
191	S	K	0.0000
192	N	K	-0.8181
193	A	K	-0.7937
194	S	K	-1.2389
195	D	K	-1.8654
196	K	K	-2.0307
197	I	K	-0.7877
198	E	K	-1.6075
199	I	K	-1.0836
200	N	K	-1.4613
201	N	K	-1.5123
202	T	K	0.0000
203	L	K	0.0000
204	E	K	-1.9569
205	E	K	-2.1906
206	R	K	-2.4745
207	L	K	0.0000
208	K	K	-2.6977
209	L	K	-1.1085
210	L	K	-1.1715
211	S	K	-1.8354
212	E	K	-2.4236
213	E	K	-2.3682
214	A	K	-1.3045
215	L	K	-1.5051
216	P	K	-0.9150
217	A	K	-0.5592
218	I	K	-0.3717
219	R	K	-1.1600
220	L	K	0.3425
221	E	K	-0.8264
222	L	K	0.4356
223	Y	K	0.2804
224	G	K	-0.0899