Project name: 6bft:A
Status: done
submitted: 2019-03-21 14:51:55, status changed: 2019-03-21 15:02:01
Settings
|
Chain sequence(s)
|
A: EVQLVESGGGLVQPGGSLRLSCAASGYDFDNYGMNWVRQAPGKGLEWVGWINTYTGEPTYAADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYPHYYGSSHWYFDVWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTH
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.2548
-
Maximal score value
-
2.4103
-
Average score
-
-0.5981
-
Total score value
-
-133.9675
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
A |
-2.0924 |
|
| 2 |
V |
A |
-1.3405 |
|
| 3 |
Q |
A |
-1.1937 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
V |
A |
1.1500 |
|
| 6 |
E |
A |
0.0000 |
|
| 7 |
S |
A |
-0.3592 |
|
| 8 |
G |
A |
-0.8762 |
|
| 9 |
G |
A |
-0.4276 |
|
| 10 |
G |
A |
-0.2431 |
|
| 11 |
L |
A |
0.0326 |
|
| 12 |
V |
A |
-0.6896 |
|
| 13 |
Q |
A |
-1.5615 |
|
| 14 |
P |
A |
-1.6220 |
|
| 15 |
G |
A |
-1.5539 |
|
| 16 |
G |
A |
-1.2295 |
|
| 17 |
S |
A |
-1.3224 |
|
| 18 |
L |
A |
-1.2937 |
|
| 19 |
R |
A |
-2.2331 |
|
| 20 |
L |
A |
0.0000 |
|
| 21 |
S |
A |
-0.3356 |
|
| 22 |
C |
A |
0.0000 |
|
| 23 |
A |
A |
0.0027 |
|
| 24 |
A |
A |
0.0000 |
|
| 25 |
S |
A |
-1.2036 |
|
| 26 |
G |
A |
-1.5617 |
|
| 27 |
Y |
A |
-1.5601 |
|
| 28 |
D |
A |
-2.4034 |
|
| 29 |
F |
A |
0.0000 |
|
| 30 |
D |
A |
-1.6129 |
|
| 31 |
N |
A |
-1.9730 |
|
| 32 |
Y |
A |
-0.9928 |
|
| 33 |
G |
A |
-0.2962 |
|
| 34 |
M |
A |
0.0000 |
|
| 35 |
N |
A |
0.0000 |
|
| 36 |
W |
A |
0.0000 |
|
| 37 |
V |
A |
0.0000 |
|
| 38 |
R |
A |
0.0000 |
|
| 39 |
Q |
A |
-0.5193 |
|
| 40 |
A |
A |
-1.1316 |
|
| 41 |
P |
A |
-1.0515 |
|
| 42 |
G |
A |
-1.5709 |
|
| 43 |
K |
A |
-2.1024 |
|
| 44 |
G |
A |
-0.9912 |
|
| 45 |
L |
A |
0.5284 |
|
| 46 |
E |
A |
-0.3412 |
|
| 47 |
W |
A |
0.3941 |
|
| 48 |
V |
A |
0.0000 |
|
| 49 |
G |
A |
0.0000 |
|
| 50 |
W |
A |
0.0038 |
|
| 51 |
I |
A |
0.0000 |
|
| 52 |
N |
A |
-0.9079 |
|
| 53 |
T |
A |
0.0000 |
|
| 54 |
Y |
A |
0.2272 |
|
| 55 |
T |
A |
-0.2762 |
|
| 56 |
G |
A |
-0.9706 |
|
| 57 |
E |
A |
-1.8536 |
|
| 58 |
P |
A |
-1.0303 |
|
| 59 |
T |
A |
-0.6045 |
|
| 60 |
Y |
A |
-0.6891 |
|
| 61 |
A |
A |
-0.7524 |
|
| 62 |
A |
A |
-1.5725 |
|
| 63 |
D |
A |
-2.5971 |
|
| 64 |
F |
A |
0.0000 |
|
| 65 |
K |
A |
-3.1232 |
|
| 66 |
R |
A |
-3.2548 |
|
| 67 |
R |
A |
-2.3636 |
|
| 68 |
F |
A |
0.0000 |
|
| 69 |
T |
A |
-1.2402 |
|
| 70 |
F |
A |
0.0000 |
|
| 71 |
S |
A |
-0.4198 |
|
| 72 |
L |
A |
-0.3818 |
|
| 73 |
D |
A |
-0.8622 |
|
| 74 |
T |
A |
-1.0617 |
|
| 75 |
S |
A |
-1.2516 |
|
| 76 |
K |
A |
-1.9386 |
|
| 77 |
S |
A |
-1.4570 |
|
| 78 |
T |
A |
0.0000 |
|
| 79 |
A |
A |
0.0000 |
|
| 80 |
Y |
A |
-0.4905 |
|
| 81 |
L |
A |
0.0000 |
|
| 82 |
Q |
A |
-1.5744 |
|
| 83 |
M |
A |
0.0000 |
|
| 84 |
N |
A |
-1.9504 |
|
| 85 |
S |
A |
-1.6061 |
|
| 86 |
L |
A |
0.0000 |
|
| 87 |
R |
A |
-2.6663 |
|
| 88 |
A |
A |
-1.8205 |
|
| 89 |
E |
A |
-2.3056 |
|
| 90 |
D |
A |
0.0000 |
|
| 91 |
T |
A |
-0.7524 |
|
| 92 |
A |
A |
0.0000 |
|
| 93 |
V |
A |
0.3830 |
|
| 94 |
Y |
A |
0.0000 |
|
| 95 |
Y |
A |
0.3626 |
|
| 96 |
C |
A |
0.0000 |
|
| 97 |
A |
A |
0.0000 |
|
| 98 |
K |
A |
0.0000 |
|
| 99 |
Y |
A |
0.0000 |
|
| 100 |
P |
A |
0.1183 |
|
| 101 |
H |
A |
-0.4784 |
|
| 102 |
Y |
A |
1.1699 |
|
| 103 |
Y |
A |
1.2889 |
|
| 104 |
G |
A |
0.1456 |
|
| 105 |
S |
A |
-0.0183 |
|
| 106 |
S |
A |
0.0204 |
|
| 107 |
H |
A |
0.0970 |
|
| 108 |
W |
A |
1.4382 |
|
| 109 |
Y |
A |
1.6797 |
|
| 110 |
F |
A |
1.1442 |
|
| 111 |
D |
A |
0.1871 |
|
| 112 |
V |
A |
0.1896 |
|
| 113 |
W |
A |
0.3236 |
|
| 114 |
G |
A |
-0.0018 |
|
| 115 |
Q |
A |
-0.7173 |
|
| 116 |
G |
A |
-0.1107 |
|
| 117 |
T |
A |
0.0476 |
|
| 118 |
L |
A |
0.1214 |
|
| 119 |
V |
A |
0.0000 |
|
| 120 |
T |
A |
-0.3594 |
|
| 121 |
V |
A |
-0.9427 |
|
| 122 |
S |
A |
-0.7011 |
|
| 123 |
S |
A |
-0.6044 |
|
| 124 |
A |
A |
-0.3914 |
|
| 125 |
S |
A |
-0.4391 |
|
| 126 |
T |
A |
-0.6805 |
|
| 127 |
K |
A |
-1.3857 |
|
| 128 |
G |
A |
-1.6487 |
|
| 129 |
P |
A |
-0.7651 |
|
| 130 |
S |
A |
-0.1709 |
|
| 131 |
V |
A |
0.0000 |
|
| 132 |
F |
A |
1.0089 |
|
| 133 |
P |
A |
-0.1208 |
|
| 134 |
L |
A |
0.3483 |
|
| 135 |
A |
A |
-0.8675 |
|
| 136 |
P |
A |
0.0000 |
|
| 137 |
S |
A |
-0.7541 |
|
| 144 |
G |
A |
-0.6387 |
|
| 145 |
T |
A |
-0.4701 |
|
| 146 |
A |
A |
-0.2722 |
|
| 147 |
A |
A |
0.0950 |
|
| 148 |
L |
A |
0.0000 |
|
| 149 |
G |
A |
0.0000 |
|
| 150 |
C |
A |
0.0000 |
|
| 151 |
L |
A |
0.7014 |
|
| 152 |
V |
A |
0.0000 |
|
| 153 |
K |
A |
-0.2477 |
|
| 154 |
D |
A |
-0.7288 |
|
| 155 |
Y |
A |
0.0000 |
|
| 156 |
F |
A |
-0.3404 |
|
| 157 |
P |
A |
0.0000 |
|
| 158 |
E |
A |
-0.5782 |
|
| 159 |
P |
A |
-0.7891 |
|
| 160 |
V |
A |
-0.8710 |
|
| 161 |
T |
A |
-0.8127 |
|
| 162 |
V |
A |
-0.5476 |
|
| 163 |
S |
A |
-0.4649 |
|
| 164 |
W |
A |
0.0000 |
|
| 165 |
N |
A |
-0.8423 |
|
| 166 |
S |
A |
-0.6923 |
|
| 167 |
G |
A |
-0.6073 |
|
| 168 |
A |
A |
-0.2756 |
|
| 169 |
L |
A |
-0.0699 |
|
| 170 |
T |
A |
-0.3010 |
|
| 171 |
S |
A |
-0.3939 |
|
| 172 |
G |
A |
-0.4212 |
|
| 173 |
V |
A |
0.1024 |
|
| 174 |
H |
A |
-0.3418 |
|
| 175 |
T |
A |
0.2168 |
|
| 176 |
F |
A |
0.9498 |
|
| 177 |
P |
A |
0.7040 |
|
| 178 |
A |
A |
1.2086 |
|
| 179 |
V |
A |
2.4103 |
|
| 180 |
L |
A |
1.9780 |
|
| 181 |
Q |
A |
0.5523 |
|
| 182 |
S |
A |
0.0177 |
|
| 183 |
S |
A |
-0.2823 |
|
| 184 |
G |
A |
0.1541 |
|
| 185 |
L |
A |
0.1994 |
|
| 186 |
Y |
A |
0.7384 |
|
| 187 |
S |
A |
0.0000 |
|
| 188 |
L |
A |
0.0000 |
|
| 189 |
S |
A |
0.6574 |
|
| 190 |
S |
A |
0.0000 |
|
| 191 |
V |
A |
0.4815 |
|
| 192 |
V |
A |
0.0000 |
|
| 193 |
T |
A |
-0.1998 |
|
| 194 |
V |
A |
0.0000 |
|
| 195 |
P |
A |
-0.5875 |
|
| 196 |
S |
A |
-0.5507 |
|
| 197 |
S |
A |
-0.6196 |
|
| 198 |
S |
A |
-0.6362 |
|
| 199 |
L |
A |
-0.8584 |
|
| 200 |
G |
A |
-1.0161 |
|
| 201 |
T |
A |
-0.7578 |
|
| 202 |
Q |
A |
-1.3198 |
|
| 203 |
T |
A |
-1.2159 |
|
| 204 |
Y |
A |
0.0000 |
|
| 205 |
I |
A |
-1.5442 |
|
| 206 |
C |
A |
0.0000 |
|
| 207 |
N |
A |
-1.7286 |
|
| 208 |
V |
A |
0.0000 |
|
| 209 |
N |
A |
-2.6418 |
|
| 210 |
H |
A |
0.0000 |
|
| 211 |
K |
A |
-2.9393 |
|
| 212 |
P |
A |
-1.6600 |
|
| 213 |
S |
A |
-1.9723 |
|
| 214 |
N |
A |
-2.7062 |
|
| 215 |
T |
A |
-2.3397 |
|
| 216 |
K |
A |
-3.0486 |
|
| 217 |
V |
A |
-2.0557 |
|
| 218 |
D |
A |
-2.7305 |
|
| 219 |
K |
A |
-2.2267 |
|
| 220 |
K |
A |
-2.6130 |
|
| 221 |
V |
A |
0.0000 |
|
| 222 |
E |
A |
-2.8699 |
|
| 223 |
P |
A |
-1.8116 |
|
| 224 |
K |
A |
-2.2935 |
|
| 225 |
S |
A |
-1.5629 |
|
| 226 |
C |
A |
-1.2518 |
|
| 227 |
D |
A |
-2.4965 |
|
| 228 |
K |
A |
-2.6316 |
|
| 229 |
T |
A |
-1.6452 |
|
| 230 |
H |
A |
-1.4087 |
|