Project name: 5n2k:B

Chain sequence(s)	B: QVQLVESGGGVVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAFIRYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCCKTHGSHDNWGQGTMVTVSSASTKGPSVFPLAPSGTAALGCCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9001
• Maximal score value: 2.4211
• Average score: -0.6105
• Total score value: -129.4242

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.1723
2	V	B	-0.4895
3	Q	B	-1.0521
4	L	B	0.0000
5	V	B	0.5378
6	E	B	0.0000
7	S	B	-0.4237
8	G	B	-0.9315
9	G	B	-0.1534
10	G	B	0.7499
11	V	B	1.6197
12	V	B	-0.1230
13	Q	B	-1.3546
14	P	B	-1.9183
15	G	B	-2.1309
16	R	B	-2.6923
17	S	B	-1.9257
18	L	B	-1.3218
19	R	B	-2.1087
20	L	B	0.0000
21	S	B	-0.4764
22	C	B	0.0000
23	A	B	-0.2354
24	A	B	0.0000
25	S	B	-0.5291
26	G	B	-0.7375
27	F	B	-0.1296
28	T	B	0.0884
29	F	B	0.0000
30	S	B	-0.8219
31	S	B	-0.1683
32	Y	B	0.0548
33	G	B	-0.6954
34	M	B	0.0000
35	H	B	-0.1914
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.5099
40	A	B	-1.0981
41	P	B	-0.9172
42	G	B	-1.4117
43	K	B	-2.1054
44	G	B	-0.9590
45	L	B	0.4717
46	E	B	-0.3724
47	W	B	0.2847
48	V	B	0.0000
49	A	B	0.0000
50	F	B	0.0000
51	I	B	0.0000
52	R	B	-1.6307
53	Y	B	-0.5702
54	D	B	-1.8392
55	G	B	-1.8055
56	S	B	-1.5371
57	N	B	-1.7371
58	K	B	-0.9973
59	Y	B	0.1242
60	Y	B	-0.4151
61	A	B	-1.1079
62	D	B	-2.3632
63	S	B	-1.7847
64	V	B	0.0000
65	K	B	-2.4594
66	G	B	-1.7728
67	R	B	-1.5119
68	F	B	0.0000
69	T	B	-0.8201
70	I	B	0.0000
71	S	B	-0.9801
72	R	B	-1.4015
73	D	B	-2.1732
74	N	B	-1.9818
75	S	B	-1.7093
76	K	B	-2.5104
77	N	B	-1.8059
78	T	B	0.0000
79	L	B	0.0000
80	Y	B	-0.6651
81	L	B	0.0000
82	Q	B	-1.2786
83	M	B	0.0000
84	N	B	-1.9198
85	S	B	-1.7501
86	L	B	0.0000
87	R	B	-2.6038
88	A	B	-1.8490
89	E	B	-2.3206
90	D	B	0.0000
91	T	B	-0.6105
92	A	B	0.0000
93	V	B	0.3501
94	Y	B	0.0000
95	Y	B	0.2980
96	C	B	0.0000
97	K	B	-0.6601
98	T	B	0.0000
99	H	B	-1.2777
100	G	B	-1.3102
101	S	B	-1.2654
102	H	B	-1.7953
103	D	B	-1.6448
104	N	B	-1.2281
105	W	B	-0.3229
106	G	B	-0.3134
107	Q	B	-0.8863
108	G	B	0.0000
109	T	B	0.0830
110	M	B	0.5912
111	V	B	0.0000
112	T	B	0.2405
113	V	B	0.0000
114	S	B	-0.6410
115	S	B	-0.5606
116	A	B	-0.3626
117	S	B	-0.4154
118	T	B	-0.5725
119	K	B	-1.0539
120	G	B	-1.3301
121	P	B	0.0000
122	S	B	-0.0320
123	V	B	0.0000
124	F	B	0.9415
125	P	B	0.0084
126	L	B	0.1421
127	A	B	-0.9452
128	P	B	0.0000
129	S	B	-0.5961
136	G	B	-0.6759
137	T	B	-0.4633
138	A	B	-0.2861
139	A	B	0.0939
140	L	B	0.0000
141	G	B	0.0000
142	C	B	0.0000
143	L	B	0.7560
144	V	B	0.0000
145	K	B	0.0104
146	D	B	-0.2662
147	Y	B	0.0000
148	F	B	-0.1729
149	P	B	-0.7015
150	E	B	-0.9022
151	P	B	-0.9082
152	V	B	-0.6753
153	T	B	-0.5659
154	V	B	-0.3994
155	S	B	-0.3290
156	W	B	0.0000
157	N	B	-0.8429
158	S	B	-0.6456
159	G	B	-0.3723
160	A	B	-0.1902
161	L	B	-0.0302
162	T	B	-0.2984
163	S	B	-0.3970
164	G	B	-0.5091
165	V	B	0.0040
166	H	B	-0.4215
167	T	B	0.3017
168	F	B	1.3202
169	P	B	0.9006
170	A	B	1.2534
171	V	B	2.4211
172	L	B	1.9115
173	Q	B	0.7093
174	S	B	-0.2235
175	S	B	-0.2039
176	G	B	0.0000
177	L	B	0.3679
178	Y	B	0.7802
179	S	B	0.0000
180	L	B	0.0000
181	S	B	0.8176
182	S	B	0.0000
183	V	B	0.5014
184	V	B	0.0000
185	T	B	-0.2508
186	V	B	0.0000
187	P	B	-0.5300
188	S	B	-0.5959
189	S	B	-0.6630
190	S	B	-0.7170
191	L	B	-0.8496
192	G	B	-1.0335
193	T	B	-0.7709
194	Q	B	-1.2929
195	T	B	-1.1957
196	Y	B	0.0000
197	I	B	-1.5069
198	C	B	0.0000
199	N	B	-1.5840
200	V	B	0.0000
201	N	B	-1.8258
202	H	B	0.0000
203	K	B	-2.7512
204	P	B	-1.6065
205	S	B	-1.7656
206	N	B	-2.5188
207	T	B	-2.0282
208	K	B	-2.6974
209	V	B	-1.8811
210	D	B	-2.7438
211	K	B	-2.3136
212	K	B	-2.5903
213	V	B	0.0000
214	E	B	-2.9001
215	P	B	-1.8739
216	K	B	-2.1534
217	S	B	-0.9940
218	C	B	0.2370