Project name: e1657545119c78f

Chain sequence(s)	B: MMVLDVVAFVLEGSDKIGEADFNRRSSKEEFMEEEVIQRMDVGQDDSSIHVTVLLQYSYYMVTVEYPFSEAQSKGDILQRRVREIRRYQGGNRRTNTGLALRYLSSDHSFLVSQGDDREQQAPNLLVVYYMMVVTTGGNPASDEEIKKRLPGDIQQVVPIGVGPNANVQQELERIGWPNAPILIQDFETLPREAPDLVLQRRCCS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.7655
• Maximal score value: 0.9763
• Average score: -0.9566
• Total score value: -169.3199

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1495	M	B	0.8719
1496	V	B	0.6071
1497	L	B	0.0000
1498	D	B	0.0000
1499	V	B	0.0000
1500	A	B	0.0000
1501	F	B	0.0000
1502	V	B	0.0000
1503	L	B	0.0000
1504	E	B	0.0000
1505	G	B	0.0000
1506	S	B	0.0000
1507	D	B	-3.4075
1508	K	B	-3.4207
1509	I	B	0.0000
1510	G	B	-2.4537
1511	E	B	-3.0888
1512	A	B	-1.8469
1513	D	B	-2.5271
1514	F	B	0.0000
1515	N	B	-3.1180
1516	R	B	-2.9226
1517	S	B	0.0000
1518	K	B	-2.6157
1519	E	B	-3.3156
1520	F	B	0.0000
1521	M	B	0.0000
1522	E	B	-2.5639
1523	E	B	-3.1701
1524	V	B	0.0000
1525	I	B	0.0000
1526	Q	B	-2.9256
1527	R	B	-3.2602
1528	M	B	0.0000
1529	D	B	-2.4113
1530	V	B	-1.6711
1531	G	B	-1.5222
1532	Q	B	-2.2988
1533	D	B	-2.2188
1534	S	B	-0.9036
1535	I	B	0.0000
1536	H	B	0.0000
1537	V	B	0.0000
1538	T	B	0.0000
1539	V	B	0.0000
1540	L	B	0.0000
1541	Q	B	0.0000
1542	Y	B	0.0000
1543	S	B	0.0000
1544	Y	B	0.5895
1545	M	B	0.9763
1546	V	B	0.8824
1547	T	B	0.7240
1548	V	B	0.8265
1549	E	B	-0.3024
1550	Y	B	0.0000
1551	P	B	-0.1839
1552	F	B	0.0000
1553	S	B	-0.4832
1554	E	B	-1.3053
1555	A	B	-1.1728
1556	Q	B	0.0000
1557	S	B	-1.5940
1558	K	B	-2.2791
1559	G	B	-2.0521
1560	D	B	-2.7698
1561	I	B	0.0000
1562	L	B	-2.4805
1563	Q	B	-3.1595
1564	R	B	-2.9715
1565	V	B	0.0000
1566	R	B	-3.7655
1567	E	B	-3.2071
1568	I	B	0.0000
1569	R	B	-2.8931
1570	Y	B	-1.9024
1571	Q	B	-1.0025
1572	G	B	-1.8344
1573	G	B	-1.5011
1574	N	B	-2.2565
1575	R	B	-1.8074
1576	T	B	0.0000
1577	N	B	0.0000
1578	T	B	0.0000
1579	G	B	0.0000
1580	L	B	-0.4344
1581	A	B	0.0000
1582	L	B	0.0000
1583	R	B	-2.5106
1584	Y	B	-1.1436
1585	L	B	0.0000
1586	S	B	-1.2561
1587	D	B	-2.0445
1588	H	B	-0.9588
1589	S	B	0.0000
1590	F	B	0.0235
1591	L	B	0.8360
1592	V	B	0.4535
1593	S	B	-1.0647
1594	Q	B	-2.3477
1595	G	B	-2.7490
1596	D	B	-3.3244
1597	R	B	-2.8723
1598	E	B	-3.3723
1599	Q	B	-3.0777
1600	A	B	0.0000
1601	P	B	-1.1341
1602	N	B	-1.0902
1603	L	B	0.0000
1604	V	B	0.0000
1605	Y	B	0.0000
1606	M	B	0.0000
1607	V	B	0.0000
1608	T	B	0.0000
1609	G	B	0.0000
1610	N	B	0.0000
1611	P	B	-0.7745
1612	A	B	-0.8583
1613	S	B	-0.9758
1614	D	B	-1.4605
1615	E	B	-2.2721
1616	I	B	0.0000
1617	K	B	-2.6810
1618	R	B	-2.2287
1619	L	B	0.0000
1620	P	B	-1.4745
1621	G	B	-1.6172
1622	D	B	-2.3982
1623	I	B	0.0000
1624	Q	B	-1.0455
1625	V	B	0.0000
1626	V	B	0.0000
1627	P	B	0.0000
1628	I	B	0.0000
1629	G	B	0.0000
1630	V	B	0.0000
1631	G	B	-1.3138
1632	P	B	-1.0694
1633	N	B	-1.6434
1634	A	B	0.0000
1635	N	B	-0.8440
1636	V	B	-0.2166
1637	Q	B	-1.4502
1638	E	B	-1.2111
1639	L	B	0.0000
1640	E	B	-1.1042
1641	R	B	-1.5813
1642	I	B	0.0000
1643	G	B	0.0000
1644	W	B	0.2701
1645	P	B	0.0695
1646	N	B	-0.1196
1647	A	B	0.2086
1648	P	B	0.2027
1649	I	B	0.6987
1650	L	B	0.7848
1651	I	B	0.0000
1652	Q	B	-1.6008
1653	D	B	-1.9751
1654	F	B	0.0000
1655	E	B	-2.8439
1656	T	B	-2.3654
1657	L	B	0.0000
1658	P	B	-2.8797
1659	R	B	-3.5697
1660	E	B	-2.9970
1661	A	B	0.0000
1662	P	B	0.0000
1663	D	B	-2.2929
1664	L	B	-0.8268
1665	V	B	0.0000
1666	L	B	-1.3102
1667	Q	B	-1.6444
1668	R	B	-1.4445
1669	C	B	-0.7189
1670	C	B	-0.7761
1671	S	B	-0.7930