Project name: 5c0s:H

Chain sequence(s)	H: EVQLVESGAEVKKPGSSVKVSCKASGGPFRSYAISWVRQAPGQGPEWMGGIIPIFGTTKYAPKFQGRVTITADDFAGTVYMELSSLRSEDTAMYYCAKHMGYQVRETMDVWGKGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0561
• Maximal score value: 2.9297
• Average score: -0.5753
• Total score value: -127.1435

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9807
2	V	H	-1.4094
3	Q	H	-1.6876
4	L	H	0.0000
5	V	H	-0.3184
6	E	H	-0.6753
7	S	H	-0.6676
8	G	H	-0.5238
9	A	H	-0.3070
10	E	H	-0.4951
11	V	H	-0.0724
12	K	H	-1.2590
13	K	H	-2.0445
14	P	H	-2.1227
15	G	H	-1.5537
16	S	H	-1.2450
17	S	H	-1.4658
18	V	H	0.0000
19	K	H	-2.1299
20	V	H	0.0000
21	S	H	-0.9284
22	C	H	0.0000
23	K	H	-1.9937
24	A	H	-1.1330
25	S	H	-1.1332
26	G	H	-1.0584
27	G	H	-0.2478
28	P	H	0.0116
29	F	H	1.3418
30	R	H	0.6451
31	S	H	0.6509
32	Y	H	0.9352
33	A	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-1.0105
40	A	H	-1.2838
41	P	H	-1.2742
42	G	H	-1.3998
43	Q	H	-1.9933
44	G	H	-1.5918
45	P	H	-1.2478
46	E	H	-1.3598
47	W	H	-0.6292
48	M	H	0.0000
49	G	H	0.0000
50	G	H	0.0000
51	I	H	0.0000
52	I	H	0.0000
52A	P	H	0.0000
53	I	H	2.9297
54	F	H	2.8626
55	G	H	0.8607
56	T	H	0.2335
57	T	H	-0.6546
58	K	H	-1.8466
59	Y	H	-1.4489
60	A	H	0.0000
61	P	H	-1.7813
62	K	H	-2.3390
63	F	H	0.0000
64	Q	H	-2.3513
65	G	H	-1.5717
66	R	H	-1.3860
67	V	H	0.0000
68	T	H	-1.0285
69	I	H	0.0000
70	T	H	-0.5823
71	A	H	-0.5233
72	D	H	-1.1862
73	D	H	-0.7152
74	F	H	1.1497
75	A	H	-0.0101
76	G	H	0.0000
77	T	H	0.0000
78	V	H	0.0000
79	Y	H	-0.7996
80	M	H	0.0000
81	E	H	-1.6682
82	L	H	0.0000
82A	S	H	-1.2423
82B	S	H	-1.2236
82C	L	H	0.0000
83	R	H	-3.0561
84	S	H	-2.3818
85	E	H	-2.5674
86	D	H	0.0000
87	T	H	-1.0690
88	A	H	0.0000
89	M	H	0.0235
90	Y	H	0.0000
91	Y	H	0.0244
92	C	H	0.0000
93	A	H	0.0000
94	K	H	0.0000
95	H	H	0.0000
96	M	H	0.3351
97	G	H	0.2770
98	Y	H	1.0226
99	Q	H	-0.9079
100	V	H	-1.4250
100A	R	H	-2.6282
100B	E	H	-2.7665
100C	T	H	-1.6441
100D	M	H	-0.9123
101	D	H	-1.0077
102	V	H	-0.6244
103	W	H	-0.0409
104	G	H	0.0000
105	K	H	-1.4128
106	G	H	0.0000
107	T	H	0.0000
108	T	H	0.0389
109	V	H	0.0000
110	T	H	-0.7161
111	V	H	0.0000
112	S	H	-1.2149
113	S	H	-1.1121
114	A	H	-0.6113
115	S	H	-0.6815
116	T	H	-0.7280
117	K	H	-1.4245
118	G	H	-1.5326
119	P	H	-0.7721
120	S	H	-0.2421
121	V	H	0.0000
122	F	H	0.8490
123	P	H	0.0035
124	L	H	0.5582
125	A	H	-0.4808
126	P	H	0.0000
127	S	H	-1.0679
128	S	H	-1.3116
129	K	H	-1.9626
130	S	H	-1.2059
131	T	H	-1.1092
132	S	H	-0.9582
133	G	H	-0.9187
134	G	H	-0.9000
135	T	H	-0.6393
136	A	H	0.0000
137	A	H	-0.1581
138	L	H	0.0000
139	G	H	0.0000
140	C	H	0.0000
141	L	H	0.5763
142	V	H	0.0000
143	K	H	-0.7530
144	D	H	-0.9993
145	Y	H	0.0000
146	F	H	0.0000
147	P	H	-0.8952
148	E	H	-1.0648
149	P	H	-0.9929
150	V	H	-0.7053
151	T	H	-0.5863
152	V	H	-0.1910
153	S	H	-0.4309
154	W	H	0.0000
155	N	H	-0.8393
156	S	H	-0.7106
157	G	H	-0.5382
158	A	H	-0.2111
159	L	H	0.0581
160	T	H	-0.2250
161	S	H	-0.3364
162	G	H	-0.4111
163	V	H	0.0866
164	H	H	-0.2568
165	T	H	0.4115
166	F	H	1.3377
167	P	H	0.7065
168	A	H	1.2344
169	V	H	2.5361
170	L	H	2.0515
171	Q	H	0.4117
172	S	H	-0.0507
173	S	H	-0.3333
174	G	H	-0.1245
175	L	H	-0.0024
176	Y	H	0.4403
177	S	H	0.0000
178	L	H	0.0000
179	S	H	0.7388
180	S	H	0.0000
181	V	H	0.5146
182	V	H	0.0000
183	T	H	-0.1906
184	V	H	0.0000
185	P	H	-0.6312
186	S	H	-0.6536
187	S	H	-0.6509
188	S	H	-0.6512
189	L	H	-0.8780
190	G	H	-1.1468
191	T	H	-0.7881
192	Q	H	-1.4002
193	T	H	-1.2021
194	Y	H	0.0000
195	I	H	-1.4549
196	C	H	0.0000
197	N	H	-1.6268
198	V	H	0.0000
199	N	H	-1.7025
200	H	H	0.0000
201	K	H	-2.7825
202	P	H	-1.7563
203	S	H	-1.8555
204	N	H	-2.5940
205	T	H	-2.0088
206	K	H	-2.5853
207	V	H	-1.4908
208	D	H	-2.7172
209	K	H	-2.2426
210	R	H	-2.7733
211	V	H	0.0000
212	E	H	-2.5503
213	P	H	-1.2161