Project name: 4llu:A

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGFTFTDYTMDWVRQAPGKGLEWVADVNPNSGGSIYNQRFKGRFTLSVDRSKNTLYLQMNSLRAEDTAVYYCARNLGPSFYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0694
• Maximal score value: 2.4498
• Average score: -0.5845
• Total score value: -128.5804

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.1342
2	V	A	-1.2901
3	Q	A	-1.4239
4	L	A	0.0000
5	V	A	0.2937
6	E	A	0.0000
7	S	A	-0.6029
8	G	A	-1.1310
9	G	A	-0.8258
10	G	A	-0.4079
11	L	A	-0.0810
12	V	A	-0.6812
13	Q	A	-1.5308
14	P	A	-1.8975
15	G	A	-1.5442
16	G	A	-1.1905
17	S	A	-1.3931
18	L	A	-1.2463
19	R	A	-2.2577
20	L	A	0.0000
21	S	A	-0.5403
22	C	A	0.0000
23	A	A	-0.4984
24	A	A	0.0000
25	S	A	-1.2034
26	G	A	-1.2235
27	F	A	-0.7389
28	T	A	-0.6531
29	F	A	0.0000
30	T	A	-1.6890
31	D	A	-1.7065
32	Y	A	-0.4267
33	T	A	-0.1505
34	M	A	0.0000
35	D	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	0.0000
39	Q	A	-0.3536
40	A	A	-1.0450
41	P	A	-1.2235
42	G	A	-1.4187
43	K	A	-2.0277
44	G	A	-0.8597
45	L	A	0.7049
46	E	A	0.1622
47	W	A	0.5090
48	V	A	0.0000
49	A	A	0.0000
50	D	A	0.0000
51	V	A	0.0000
52	N	A	-1.1074
52A	P	A	0.0000
53	N	A	-2.1193
54	S	A	-1.2184
55	G	A	-1.0458
56	G	A	-0.5440
57	S	A	0.5275
58	I	A	1.4258
59	Y	A	-0.2337
60	N	A	-1.3188
61	Q	A	-2.6011
62	R	A	-3.0694
63	F	A	0.0000
64	K	A	-2.6455
65	G	A	-1.8878
66	R	A	-1.8104
67	F	A	0.0000
68	T	A	-0.7420
69	L	A	0.0000
70	S	A	-0.5932
71	V	A	-1.2282
72	D	A	-1.9415
73	R	A	-2.8003
74	S	A	-2.0944
75	K	A	-2.7798
76	N	A	-2.3063
77	T	A	0.0000
78	L	A	0.0000
79	Y	A	-0.6020
80	L	A	0.0000
81	Q	A	-1.5827
82	M	A	0.0000
82A	N	A	-1.5149
82B	S	A	-1.3558
82C	L	A	0.0000
83	R	A	-2.8721
84	A	A	-1.9934
85	E	A	-2.4264
86	D	A	0.0000
87	T	A	-0.8569
88	A	A	0.0000
89	V	A	0.4284
90	Y	A	0.0000
91	Y	A	0.3428
92	C	A	0.0000
93	A	A	0.0000
94	R	A	0.0000
95	N	A	0.0000
96	L	A	1.2549
97	G	A	0.3093
98	P	A	0.2109
99	S	A	0.7117
99A	F	A	1.3275
99B	Y	A	1.6031
100	F	A	0.7920
101	D	A	-0.5991
102	Y	A	-0.0586
103	W	A	0.0888
104	G	A	-0.2122
105	Q	A	-0.9564
106	G	A	-0.2915
107	T	A	-0.0899
108	L	A	0.2150
109	V	A	0.0000
110	T	A	0.0000
111	V	A	0.0000
112	S	A	-1.0284
113	S	A	-0.5577
114	A	A	-0.4018
115	S	A	-0.5058
116	T	A	-0.5993
117	K	A	-0.9950
118	G	A	-1.2923
119	P	A	0.0000
120	S	A	-0.0041
121	V	A	0.0000
122	F	A	1.1333
123	P	A	-0.1052
124	L	A	0.2404
125	A	A	-0.8909
126	P	A	0.0000
127	S	A	-1.0277
128	S	A	-1.4226
129	K	A	-2.1202
130	S	A	-1.2886
131	T	A	-1.0797
132	S	A	-0.9580
133	G	A	-1.0696
134	G	A	-1.1761
135	T	A	-0.8688
136	A	A	0.0000
137	A	A	-0.3244
138	L	A	0.0000
139	G	A	0.0000
140	C	A	0.0000
141	L	A	0.8026
142	V	A	0.0000
143	K	A	0.0269
144	D	A	-0.2721
145	Y	A	0.0000
146	F	A	-0.1184
147	P	A	0.0000
148	E	A	-0.3583
149	P	A	-0.6683
150	V	A	-0.6183
151	T	A	-0.5419
152	V	A	-0.3630
153	S	A	-0.5391
154	W	A	0.0000
155	N	A	-0.9593
156	S	A	-0.7869
157	G	A	-0.6247
158	A	A	-0.2894
159	L	A	-0.0771
160	T	A	-0.3398
161	S	A	-0.3946
162	G	A	-0.5136
163	V	A	-0.0567
164	H	A	-0.5131
165	T	A	0.2339
166	F	A	1.1488
167	P	A	0.7821
168	A	A	1.3173
169	V	A	2.4498
170	L	A	2.0048
171	Q	A	0.6407
172	S	A	0.0158
173	S	A	-0.2755
174	G	A	-0.0364
175	L	A	0.4027
176	Y	A	0.8752
177	S	A	0.0000
178	L	A	0.0000
179	S	A	0.7672
180	S	A	0.0000
181	V	A	0.4358
182	V	A	0.0000
183	T	A	-0.2706
184	V	A	0.0000
185	P	A	-0.4603
186	S	A	-0.6867
187	S	A	-1.1291
188	S	A	-1.0858
189	L	A	0.0000
190	G	A	-0.8909
191	T	A	-0.8059
192	Q	A	-1.3867
193	T	A	-1.1475
194	Y	A	0.0000
195	I	A	-1.3754
196	C	A	0.0000
197	N	A	-1.6863
198	V	A	0.0000
199	N	A	-1.8370
200	H	A	0.0000
201	K	A	-2.7533
202	P	A	-1.5160
203	S	A	-1.7002
204	N	A	-2.4839
205	T	A	-2.0132
206	K	A	-2.7137
207	V	A	-1.7381
208	D	A	-2.7200
209	K	A	-2.1230
210	K	A	-2.4717
211	V	A	0.0000
212	E	A	-2.7940
213	P	A	-1.8408
214	K	A	-2.1766