Project name: 2df6 modified

Chain sequence(s)	A: GPLGSVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTHNGRTGWFPSNYVREI; C: PPVIAPRPEHTKSIYTRS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8292
• Maximal score value: 2.0148
• Average score: -0.7857
• Total score value: -60.4962

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
5	G	A	-0.0557
6	P	A	-0.2809
7	L	A	0.6393
8	G	A	-0.1355
9	S	A	-0.1017
10	V	A	0.1937
11	V	A	0.0000
12	R	A	-2.1524
13	A	A	0.0000
14	K	A	-2.6984
15	F	A	-2.0651
16	N	A	-2.4227
17	F	A	0.0000
18	Q	A	-1.7217
19	Q	A	-1.6856
20	T	A	-1.3136
21	N	A	-1.8420
22	E	A	-2.2313
23	D	A	-1.2495
24	E	A	0.0000
25	L	A	0.0000
26	S	A	-1.4319
27	F	A	0.0000
28	S	A	-2.0718
29	K	A	-2.8292
30	G	A	-2.0503
31	D	A	-1.7308
32	V	A	-0.8935
33	I	A	0.0000
34	H	A	-1.0627
35	V	A	0.0000
36	T	A	-0.6823
37	R	A	-1.4282
38	V	A	-0.8692
39	E	A	-1.7428
40	E	A	-2.2536
41	G	A	-1.5823
42	G	A	-0.6037
43	W	A	0.0000
44	W	A	-0.8673
45	E	A	-0.8503
46	G	A	0.0000
47	T	A	-1.3151
48	H	A	-1.5254
49	N	A	-1.9952
50	G	A	-1.7060
51	R	A	-1.8739
52	T	A	-1.3923
53	G	A	0.0000
54	W	A	0.0000
55	F	A	0.0000
56	P	A	0.0000
57	S	A	-0.7019
58	N	A	-0.4747
59	Y	A	0.0000
60	V	A	0.0000
61	R	A	-2.1078
62	E	A	-1.6066
63	I	A	0.7373
180	P	C	-0.0602
181	P	C	0.7031
182	V	C	1.8579
183	I	C	1.2167
184	A	C	0.4840
185	P	C	-0.1866
186	R	C	0.0000
187	P	C	-1.8983
188	E	C	-2.6461
189	H	C	-2.2934
190	T	C	0.0000
191	K	C	-1.6260
192	S	C	0.0788
193	I	C	2.0148
194	Y	C	1.0575
195	T	C	-0.6205
196	R	C	-1.3064
197	S	C	-1.2369