Project name: 6bi0:L
Status: done
submitted: 2019-03-21 14:55:05, status changed: 2019-03-21 15:08:07
Settings
|
Chain sequence(s)
|
L: IQMTQSPSSLSASVGDRRVTITCRASQDVNTAVVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGASQESVTEQDSKDSTYSLSSTLTLSKAAYEKHAVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-3.4245
-
Maximal score value
-
2.5622
-
Average score
-
-0.7387
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Total score value
-
-156.5967
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
I |
L |
-0.4491 |
|
| 3 |
Q |
L |
-1.3723 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.1918 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.9226 |
|
| 8 |
P |
L |
-0.7137 |
|
| 9 |
S |
L |
-1.0251 |
|
| 10 |
S |
L |
-1.0690 |
|
| 11 |
L |
L |
-0.7052 |
|
| 12 |
S |
L |
-0.9489 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-0.6540 |
|
| 15 |
V |
L |
0.2522 |
|
| 16 |
G |
L |
-0.4952 |
|
| 17 |
D |
L |
-1.5653 |
|
| 18 |
R |
L |
-2.2325 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6154 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.8401 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.9379 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-1.8035 |
|
| 27 |
Q |
L |
-2.5386 |
|
| 28 |
D |
L |
-2.7902 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
N |
L |
-2.1339 |
|
| 31 |
T |
L |
-1.2337 |
|
| 32 |
A |
L |
-0.4600 |
|
| 33 |
V |
L |
0.0000 |
|
| 34 |
A |
L |
0.6999 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.0190 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5803 |
|
| 39 |
K |
L |
-1.7572 |
|
| 40 |
P |
L |
-1.5055 |
|
| 41 |
G |
L |
-1.5580 |
|
| 42 |
K |
L |
-2.4257 |
|
| 43 |
A |
L |
-1.4751 |
|
| 44 |
P |
L |
-1.4340 |
|
| 45 |
K |
L |
-1.5469 |
|
| 46 |
L |
L |
0.0174 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
1.7490 |
|
| 50 |
S |
L |
0.4192 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
0.7326 |
|
| 53 |
F |
L |
2.5622 |
|
| 54 |
L |
L |
1.9764 |
|
| 55 |
Y |
L |
1.5295 |
|
| 56 |
S |
L |
0.4232 |
|
| 57 |
G |
L |
-0.1930 |
|
| 58 |
V |
L |
-0.0013 |
|
| 59 |
P |
L |
-0.1897 |
|
| 60 |
S |
L |
-0.3046 |
|
| 61 |
R |
L |
-0.7430 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
0.2256 |
|
| 64 |
G |
L |
-0.0377 |
|
| 65 |
S |
L |
-1.0648 |
|
| 66 |
R |
L |
-2.7089 |
|
| 67 |
S |
L |
-1.7561 |
|
| 68 |
G |
L |
-2.1517 |
|
| 69 |
T |
L |
-2.4785 |
|
| 70 |
D |
L |
-2.3279 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-1.0316 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6262 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3438 |
|
| 77 |
S |
L |
-0.9996 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.8474 |
|
| 80 |
P |
L |
-1.4150 |
|
| 81 |
E |
L |
-2.1428 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-1.3143 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-1.0867 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
-0.1004 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.1769 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
H |
L |
-0.5346 |
|
| 92 |
Y |
L |
0.0406 |
|
| 93 |
T |
L |
0.1430 |
|
| 94 |
T |
L |
-0.2096 |
|
| 95 |
P |
L |
-0.1904 |
|
| 96 |
P |
L |
-0.2603 |
|
| 97 |
T |
L |
0.0497 |
|
| 98 |
F |
L |
0.6855 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-1.2189 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.9832 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-1.2767 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
K |
L |
-1.2793 |
|
| 108 |
R |
L |
-0.8585 |
|
| 109 |
T |
L |
-0.1973 |
|
| 110 |
V |
L |
0.0925 |
|
| 111 |
A |
L |
-0.2666 |
|
| 112 |
A |
L |
-0.2934 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1758 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.2671 |
|
| 117 |
I |
L |
1.2413 |
|
| 118 |
F |
L |
1.4450 |
|
| 119 |
P |
L |
-0.0495 |
|
| 120 |
P |
L |
-0.7039 |
|
| 121 |
S |
L |
-1.7789 |
|
| 122 |
D |
L |
-3.2185 |
|
| 123 |
E |
L |
-3.4245 |
|
| 124 |
Q |
L |
-2.4294 |
|
| 125 |
L |
L |
-2.4979 |
|
| 126 |
K |
L |
-3.0473 |
|
| 127 |
S |
L |
-1.8932 |
|
| 128 |
G |
L |
-1.3562 |
|
| 129 |
T |
L |
-1.0335 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0284 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.6740 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.4799 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6809 |
|
| 138 |
N |
L |
-1.4508 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.8812 |
|
| 142 |
R |
L |
-2.9915 |
|
| 143 |
E |
L |
-3.2701 |
|
| 144 |
A |
L |
-2.3847 |
|
| 145 |
K |
L |
-2.2429 |
|
| 146 |
V |
L |
-1.0866 |
|
| 147 |
Q |
L |
-0.5433 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5760 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.7115 |
|
| 152 |
N |
L |
-1.4312 |
|
| 153 |
A |
L |
-0.3371 |
|
| 154 |
L |
L |
0.6478 |
|
| 155 |
Q |
L |
-0.2444 |
|
| 156 |
S |
L |
-0.3579 |
|
| 157 |
G |
L |
-0.8717 |
|
| 158 |
A |
L |
-0.6211 |
|
| 159 |
S |
L |
-1.2459 |
|
| 160 |
Q |
L |
-2.2127 |
|
| 161 |
E |
L |
-2.3221 |
|
| 162 |
S |
L |
-1.3173 |
|
| 163 |
V |
L |
-0.7855 |
|
| 164 |
T |
L |
-1.2924 |
|
| 165 |
E |
L |
-2.2721 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.5677 |
|
| 168 |
S |
L |
-2.3005 |
|
| 169 |
K |
L |
-2.6194 |
|
| 170 |
D |
L |
-1.9419 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-1.0976 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4758 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5651 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.2999 |
|
| 181 |
L |
L |
-0.3166 |
|
| 182 |
S |
L |
-0.7201 |
|
| 183 |
K |
L |
-1.7837 |
|
| 184 |
A |
L |
-1.3064 |
|
| 185 |
A |
L |
-1.3470 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-2.7650 |
|
| 188 |
K |
L |
-2.8637 |
|
| 189 |
H |
L |
-1.9725 |
|
| 190 |
A |
L |
-1.6454 |
|
| 191 |
V |
L |
-0.7294 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.6448 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2034 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.7757 |
|
| 200 |
G |
L |
-0.4794 |
|
| 201 |
L |
L |
-0.2370 |
|
| 202 |
S |
L |
-0.4439 |
|
| 203 |
S |
L |
-0.4395 |
|
| 204 |
P |
L |
-0.5673 |
|
| 205 |
V |
L |
-0.0704 |
|
| 206 |
T |
L |
-0.3635 |
|
| 207 |
K |
L |
-0.2644 |
|
| 208 |
S |
L |
-0.3164 |
|
| 209 |
F |
L |
-0.6389 |
|
| 210 |
N |
L |
-1.7418 |
|
| 211 |
R |
L |
-2.1166 |
|
| 212 |
G |
L |
-1.9596 |
|
| 213 |
E |
L |
-2.4403 |
|