Project name: 5id0:B
Status: done
submitted: 2019-03-20 15:56:51, status changed: 2019-03-20 17:26:47
Settings
|
Chain sequence(s)
|
B: VQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8708
-
Maximal score value
-
2.4192
-
Average score
-
-0.5064
-
Total score value
-
-110.9026
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
V |
B |
1.0981 |
|
| 3 |
Q |
B |
-0.8772 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
K |
B |
-2.4300 |
|
| 6 |
Q |
B |
-1.3442 |
|
| 7 |
S |
B |
-0.9922 |
|
| 8 |
G |
B |
-1.2370 |
|
| 9 |
P |
B |
-0.5339 |
|
| 10 |
G |
B |
-0.4075 |
|
| 11 |
L |
B |
0.0357 |
|
| 12 |
V |
B |
-0.5627 |
|
| 13 |
Q |
B |
-1.1515 |
|
| 14 |
P |
B |
-1.4017 |
|
| 15 |
S |
B |
-1.4263 |
|
| 16 |
Q |
B |
-1.7509 |
|
| 17 |
S |
B |
-1.6149 |
|
| 18 |
L |
B |
0.0000 |
|
| 19 |
S |
B |
-0.7257 |
|
| 20 |
I |
B |
0.0000 |
|
| 21 |
T |
B |
-0.6028 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
T |
B |
-1.2566 |
|
| 24 |
V |
B |
0.0000 |
|
| 25 |
S |
B |
-0.7187 |
|
| 26 |
G |
B |
-0.0249 |
|
| 27 |
F |
B |
-0.0397 |
|
| 28 |
S |
B |
-0.7260 |
|
| 29 |
L |
B |
0.0000 |
|
| 30 |
T |
B |
-0.8969 |
|
| 31 |
N |
B |
-0.8841 |
|
| 32 |
Y |
B |
0.3541 |
|
| 33 |
G |
B |
0.0000 |
|
| 34 |
V |
B |
0.0000 |
|
| 35 |
H |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.3384 |
|
| 40 |
S |
B |
-0.9510 |
|
| 41 |
P |
B |
-1.0763 |
|
| 42 |
G |
B |
-1.6100 |
|
| 43 |
K |
B |
-2.0554 |
|
| 44 |
G |
B |
-0.6702 |
|
| 45 |
L |
B |
0.6792 |
|
| 46 |
E |
B |
-0.0565 |
|
| 47 |
W |
B |
0.3866 |
|
| 48 |
L |
B |
0.0000 |
|
| 49 |
G |
B |
0.0000 |
|
| 50 |
V |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
W |
B |
-0.6004 |
|
| 53 |
S |
B |
-0.6702 |
|
| 54 |
G |
B |
-1.2299 |
|
| 55 |
G |
B |
-1.5567 |
|
| 56 |
N |
B |
-1.9058 |
|
| 57 |
T |
B |
-1.3904 |
|
| 58 |
D |
B |
-1.2671 |
|
| 59 |
Y |
B |
-0.6045 |
|
| 60 |
N |
B |
-0.6976 |
|
| 61 |
T |
B |
-0.5299 |
|
| 62 |
P |
B |
-0.4957 |
|
| 63 |
F |
B |
0.0000 |
|
| 64 |
T |
B |
-0.5993 |
|
| 65 |
S |
B |
-0.6757 |
|
| 66 |
R |
B |
-1.1575 |
|
| 67 |
L |
B |
0.0000 |
|
| 68 |
S |
B |
-1.1590 |
|
| 69 |
I |
B |
0.0000 |
|
| 70 |
N |
B |
-1.7516 |
|
| 71 |
K |
B |
-1.4615 |
|
| 72 |
D |
B |
-1.7608 |
|
| 73 |
N |
B |
-2.1065 |
|
| 74 |
S |
B |
-1.6218 |
|
| 75 |
K |
B |
-2.3394 |
|
| 76 |
S |
B |
-1.5828 |
|
| 77 |
Q |
B |
-1.5156 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
F |
B |
-0.3326 |
|
| 80 |
F |
B |
0.0000 |
|
| 81 |
K |
B |
-1.7184 |
|
| 82 |
M |
B |
0.0000 |
|
| 83 |
N |
B |
-1.9880 |
|
| 84 |
S |
B |
-1.4979 |
|
| 85 |
L |
B |
0.0000 |
|
| 86 |
Q |
B |
-1.9687 |
|
| 87 |
S |
B |
-1.4381 |
|
| 88 |
N |
B |
-2.0348 |
|
| 89 |
D |
B |
0.0000 |
|
| 90 |
T |
B |
-0.6579 |
|
| 91 |
A |
B |
0.0000 |
|
| 92 |
I |
B |
0.5545 |
|
| 93 |
Y |
B |
0.0000 |
|
| 94 |
Y |
B |
-0.1160 |
|
| 95 |
C |
B |
0.0000 |
|
| 96 |
A |
B |
0.0000 |
|
| 97 |
R |
B |
0.0000 |
|
| 98 |
A |
B |
0.0000 |
|
| 99 |
L |
B |
1.4190 |
|
| 100 |
T |
B |
1.2125 |
|
| 101 |
Y |
B |
1.8975 |
|
| 102 |
Y |
B |
1.7320 |
|
| 103 |
D |
B |
0.7277 |
|
| 104 |
Y |
B |
0.6246 |
|
| 105 |
E |
B |
-0.3409 |
|
| 106 |
F |
B |
0.4258 |
|
| 107 |
A |
B |
0.8007 |
|
| 108 |
Y |
B |
0.7239 |
|
| 109 |
W |
B |
0.2228 |
|
| 110 |
G |
B |
0.0000 |
|
| 111 |
Q |
B |
-1.5915 |
|
| 112 |
G |
B |
-0.7208 |
|
| 113 |
T |
B |
0.0000 |
|
| 114 |
L |
B |
0.1644 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
T |
B |
-0.2502 |
|
| 117 |
V |
B |
0.0000 |
|
| 118 |
S |
B |
-0.5524 |
|
| 119 |
A |
B |
-0.2294 |
|
| 120 |
A |
B |
-0.2453 |
|
| 121 |
S |
B |
-0.4675 |
|
| 122 |
T |
B |
-0.7144 |
|
| 123 |
K |
B |
-1.2138 |
|
| 124 |
G |
B |
-1.3595 |
|
| 125 |
P |
B |
0.0000 |
|
| 126 |
S |
B |
-0.0775 |
|
| 127 |
V |
B |
0.0000 |
|
| 128 |
F |
B |
0.9941 |
|
| 129 |
P |
B |
0.0360 |
|
| 130 |
L |
B |
0.3279 |
|
| 131 |
A |
B |
-1.1072 |
|
| 132 |
P |
B |
0.0000 |
|
| 133 |
S |
B |
-1.3678 |
|
| 134 |
S |
B |
-1.3292 |
|
| 135 |
K |
B |
-1.8793 |
|
| 136 |
S |
B |
-1.0027 |
|
| 137 |
T |
B |
-0.9901 |
|
| 138 |
S |
B |
-0.9580 |
|
| 139 |
G |
B |
-0.8378 |
|
| 140 |
G |
B |
-0.8888 |
|
| 141 |
T |
B |
-0.6414 |
|
| 142 |
A |
B |
0.0000 |
|
| 143 |
A |
B |
-0.1925 |
|
| 144 |
L |
B |
0.0000 |
|
| 145 |
G |
B |
0.0000 |
|
| 146 |
C |
B |
0.0000 |
|
| 147 |
L |
B |
0.6933 |
|
| 148 |
V |
B |
0.0000 |
|
| 149 |
K |
B |
-0.2301 |
|
| 150 |
D |
B |
-0.6319 |
|
| 151 |
Y |
B |
0.0000 |
|
| 152 |
F |
B |
0.0000 |
|
| 153 |
P |
B |
0.0000 |
|
| 154 |
E |
B |
-0.1663 |
|
| 155 |
P |
B |
-0.5170 |
|
| 156 |
V |
B |
-0.5450 |
|
| 157 |
T |
B |
-0.4930 |
|
| 158 |
V |
B |
-0.4184 |
|
| 159 |
S |
B |
-0.4530 |
|
| 160 |
W |
B |
0.0000 |
|
| 161 |
N |
B |
-0.8624 |
|
| 162 |
S |
B |
-0.6413 |
|
| 163 |
G |
B |
-0.4495 |
|
| 164 |
A |
B |
-0.1970 |
|
| 165 |
L |
B |
-0.0178 |
|
| 166 |
T |
B |
-0.3000 |
|
| 167 |
S |
B |
-0.3606 |
|
| 168 |
G |
B |
-0.4210 |
|
| 169 |
V |
B |
-0.1445 |
|
| 170 |
H |
B |
-0.6278 |
|
| 171 |
T |
B |
-0.0064 |
|
| 172 |
F |
B |
0.7712 |
|
| 173 |
P |
B |
0.6318 |
|
| 174 |
A |
B |
1.2327 |
|
| 175 |
V |
B |
2.4192 |
|
| 176 |
L |
B |
2.0615 |
|
| 177 |
Q |
B |
0.6362 |
|
| 178 |
S |
B |
0.0636 |
|
| 179 |
S |
B |
-0.2356 |
|
| 180 |
G |
B |
0.1962 |
|
| 181 |
L |
B |
0.2879 |
|
| 182 |
Y |
B |
0.8271 |
|
| 183 |
S |
B |
0.7064 |
|
| 184 |
L |
B |
0.0000 |
|
| 185 |
S |
B |
0.5807 |
|
| 186 |
S |
B |
0.0000 |
|
| 187 |
V |
B |
0.3043 |
|
| 188 |
V |
B |
0.0000 |
|
| 189 |
T |
B |
-0.2260 |
|
| 190 |
V |
B |
0.0000 |
|
| 191 |
P |
B |
-0.5392 |
|
| 192 |
S |
B |
-0.5954 |
|
| 193 |
S |
B |
-0.5881 |
|
| 194 |
S |
B |
-0.6232 |
|
| 195 |
L |
B |
-0.7672 |
|
| 196 |
G |
B |
-0.9313 |
|
| 197 |
T |
B |
-0.7177 |
|
| 198 |
Q |
B |
-1.2239 |
|
| 199 |
T |
B |
-1.1632 |
|
| 200 |
Y |
B |
0.0000 |
|
| 201 |
I |
B |
-1.5437 |
|
| 202 |
C |
B |
0.0000 |
|
| 203 |
N |
B |
-1.5099 |
|
| 204 |
V |
B |
0.0000 |
|
| 205 |
N |
B |
-1.7422 |
|
| 206 |
H |
B |
0.0000 |
|
| 207 |
K |
B |
-2.5306 |
|
| 208 |
P |
B |
-1.4622 |
|
| 209 |
S |
B |
-1.7021 |
|
| 210 |
N |
B |
-2.4468 |
|
| 211 |
T |
B |
-1.9529 |
|
| 212 |
K |
B |
-2.6249 |
|
| 213 |
V |
B |
-1.8017 |
|
| 214 |
D |
B |
-2.6761 |
|
| 215 |
K |
B |
-2.2165 |
|
| 216 |
R |
B |
-2.7082 |
|
| 217 |
V |
B |
0.0000 |
|
| 218 |
E |
B |
-2.8708 |
|
| 219 |
P |
B |
-1.8676 |
|
| 220 |
K |
B |
-2.2285 |
|