Project name: 1bj1:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGYTFTNYGMNWVRQAPGKGLEWVGWINTYTGEPTYAADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYPHYYGSSHWYFDVWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2593
• Maximal score value: 2.7007
• Average score: -0.4823
• Total score value: -105.1482

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.8360
2	V	H	-0.6279
3	Q	H	-1.0823
4	L	H	0.0000
5	V	H	0.5383
6	E	H	0.0000
7	S	H	-0.5156
8	G	H	-0.8611
9	G	H	-0.7120
10	G	H	-0.4026
11	L	H	-0.1413
12	V	H	0.0000
13	Q	H	-1.6806
14	P	H	-1.6087
15	G	H	-1.4792
16	G	H	0.0000
17	S	H	-1.1594
18	L	H	-1.1674
19	R	H	-2.0885
20	L	H	0.0000
21	S	H	-0.3812
22	C	H	0.0000
23	A	H	-0.2319
24	A	H	0.0000
25	S	H	-0.8436
26	G	H	-0.9964
27	Y	H	-0.5038
28	T	H	-0.3712
29	F	H	0.0000
30	T	H	-0.1839
31	N	H	-1.0633
32	Y	H	-0.4586
33	G	H	-0.2377
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.1900
39	Q	H	-0.6073
40	A	H	-1.1406
41	P	H	-1.1000
42	G	H	-1.5750
43	K	H	-2.1235
44	G	H	-1.0104
45	L	H	0.4974
46	E	H	-0.3820
47	W	H	0.3382
48	V	H	0.0000
49	G	H	0.0000
50	W	H	-0.0556
51	I	H	0.0000
52	N	H	-0.6489
53	T	H	0.0000
54	Y	H	0.6364
55	T	H	-0.1647
56	G	H	-0.8241
57	E	H	-1.8068
58	P	H	-1.2296
59	T	H	-0.6243
60	Y	H	-0.7858
61	A	H	-0.7754
62	A	H	-1.5898
63	D	H	-2.6106
64	F	H	0.0000
65	K	H	-3.1316
66	R	H	-3.2593
67	R	H	-2.2736
68	F	H	0.0000
69	T	H	-1.1117
70	F	H	0.0000
71	S	H	-0.3949
72	L	H	-0.3413
73	D	H	-1.0847
74	T	H	-0.8292
75	S	H	-1.2275
76	K	H	-2.0071
77	S	H	-1.0959
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.4575
81	L	H	0.0000
82	Q	H	-1.2647
83	M	H	0.0000
84	N	H	-1.6551
85	S	H	-1.4836
86	L	H	0.0000
87	R	H	-2.5501
88	A	H	-1.8493
89	E	H	-2.2829
90	D	H	0.0000
91	T	H	-0.8266
92	A	H	0.0000
93	V	H	0.3158
94	Y	H	0.0000
95	Y	H	0.3103
96	C	H	0.0000
97	A	H	0.0000
98	K	H	0.0000
99	Y	H	0.0000
100	P	H	0.0000
101	H	H	-0.5037
102	Y	H	1.1891
103	Y	H	1.3053
104	G	H	0.2621
105	S	H	-0.1338
106	S	H	0.0163
107	H	H	0.0761
108	W	H	1.3627
109	Y	H	1.4932
110	F	H	0.8846
111	D	H	-0.1915
112	V	H	0.1022
113	W	H	0.1951
114	G	H	-0.2100
115	Q	H	-0.9173
116	G	H	-0.2924
117	T	H	-0.1107
118	L	H	0.1157
119	V	H	0.0000
120	T	H	-0.5514
121	V	H	0.0000
122	S	H	-0.8326
123	S	H	-0.7280
124	A	H	-0.4292
125	S	H	-0.5444
126	T	H	-0.7527
127	K	H	-1.2696
128	G	H	-1.4669
129	P	H	-0.5505
130	S	H	-0.0227
131	V	H	0.0000
132	F	H	1.2098
133	P	H	0.0798
134	L	H	0.4584
135	A	H	-0.8189
136	P	H	0.0000
137	S	H	-0.5959
144	G	H	-0.6530
145	T	H	-0.5014
146	A	H	-0.2849
147	A	H	0.0823
148	L	H	0.0000
149	G	H	0.0000
150	C	H	0.0000
151	L	H	0.8164
152	V	H	0.0000
153	K	H	-0.2936
154	D	H	-0.5829
155	Y	H	0.0000
156	F	H	-0.3087
157	P	H	0.0000
158	E	H	-0.7096
159	P	H	-0.7707
160	V	H	-0.6568
161	T	H	-0.5878
162	V	H	-0.4317
163	S	H	-0.4565
164	W	H	0.0000
165	N	H	-0.7894
166	S	H	-0.6454
167	G	H	-0.4437
168	A	H	-0.1944
169	L	H	0.0375
170	T	H	-0.2466
171	S	H	-0.2863
172	G	H	-0.2989
173	V	H	0.0720
174	H	H	-0.2882
175	T	H	0.5617
176	F	H	1.8404
177	P	H	1.1733
178	A	H	1.4888
179	V	H	2.7007
180	L	H	2.2158
181	Q	H	0.7232
182	S	H	0.0867
183	S	H	-0.2262
184	G	H	0.2332
185	L	H	0.3088
186	Y	H	0.8405
187	S	H	0.0000
188	L	H	0.0000
189	S	H	0.9411
190	S	H	0.0000
191	V	H	0.4974
192	V	H	0.0000
193	T	H	-0.1853
194	V	H	0.0000
195	P	H	-0.5803
196	S	H	-0.5584
197	S	H	-0.5874
198	S	H	-0.5392
199	L	H	-0.7541
200	G	H	-0.9319
201	T	H	-0.6293
202	Q	H	-1.1071
203	T	H	-1.0529
204	Y	H	0.0000
205	I	H	-1.4004
206	C	H	0.0000
207	N	H	-1.5715
208	V	H	0.0000
209	N	H	-1.8969
210	H	H	0.0000
211	K	H	-2.8065
212	P	H	-1.6201
213	S	H	-1.8210
214	N	H	-2.6409
215	T	H	-2.0624
216	K	H	-2.7089
217	V	H	-1.6804
218	D	H	-2.6956
219	K	H	-2.2648
220	K	H	-2.5645
221	V	H	0.0000
222	E	H	-2.8327
223	P	H	-1.8460
224	K	H	-2.2322