Project name: 2xa8:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAVSGYSITSGYSWNWIRQAPGKGLEWVASITYDGSTNYNPSVKGRITISRDDSKNTFYLQMNSLRAEDTAVYYCARGSHYFGHWHFAVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0012
• Maximal score value: 2.4086
• Average score: -0.4991
• Total score value: -109.3132

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.0545
2	V	H	-1.0420
3	Q	H	-1.3635
4	L	H	0.0000
5	V	H	0.3371
6	E	H	0.0000
7	S	H	-0.5567
8	G	H	-1.2061
9	G	H	-0.8852
10	G	H	-0.3951
11	L	H	-0.0185
12	V	H	-0.5842
13	Q	H	-1.5269
14	P	H	-1.6999
15	G	H	-1.5816
16	G	H	-1.3156
17	S	H	-1.7153
18	L	H	0.0000
19	R	H	-2.4430
20	L	H	0.0000
21	S	H	-0.5610
22	C	H	0.0000
23	A	H	-0.3130
24	V	H	0.0000
25	S	H	-0.7638
26	G	H	-1.1135
27	Y	H	-0.4181
28	S	H	-0.6746
29	I	H	0.0000
30	T	H	-0.6692
31	S	H	0.0283
32	G	H	0.0000
33	Y	H	0.1236
34	S	H	0.0000
35	W	H	0.0000
36	N	H	0.0000
37	W	H	0.0000
38	I	H	0.0000
39	R	H	0.0000
40	Q	H	-0.3057
41	A	H	-0.9881
42	P	H	-0.9174
43	G	H	-1.5384
44	K	H	-1.9667
45	G	H	-0.8590
46	L	H	0.7142
47	E	H	0.0077
48	W	H	0.3340
49	V	H	0.0000
50	A	H	0.0000
51	S	H	0.0000
52	I	H	0.0000
53	T	H	-0.3843
54	Y	H	0.0594
55	D	H	-1.4493
56	G	H	-1.0975
57	S	H	-0.9652
58	T	H	-0.8898
59	N	H	-1.2915
60	Y	H	-0.9704
61	N	H	-1.0471
62	P	H	-1.4389
63	S	H	-0.9861
64	V	H	0.0000
65	K	H	-2.1869
66	G	H	-1.6461
67	R	H	-1.5066
68	I	H	0.0000
69	T	H	-0.8607
70	I	H	0.0000
71	S	H	-0.6666
72	R	H	-1.4548
73	D	H	-2.3253
74	D	H	-3.0012
75	S	H	-2.2573
76	K	H	-2.8031
77	N	H	-2.1072
78	T	H	0.0000
79	F	H	0.0000
80	Y	H	-0.6445
81	L	H	0.0000
82	Q	H	-1.7621
83	M	H	0.0000
84	N	H	-2.1100
85	S	H	-1.5549
86	L	H	0.0000
87	R	H	-2.5686
88	A	H	-1.7680
89	E	H	-2.3013
90	D	H	0.0000
91	T	H	-0.7409
92	A	H	0.0000
93	V	H	0.1473
94	Y	H	0.0000
95	Y	H	0.2959
96	C	H	0.0000
97	A	H	0.0000
98	R	H	-0.0814
99	G	H	0.0000
100	S	H	0.2455
101	H	H	0.0947
102	Y	H	1.6527
103	F	H	2.0697
104	G	H	0.5986
105	H	H	0.3787
106	W	H	0.3153
107	H	H	-0.2887
108	F	H	0.1572
109	A	H	0.2716
110	V	H	0.1914
111	W	H	0.3284
112	G	H	-0.2794
113	Q	H	-0.9677
114	G	H	-0.3127
115	T	H	-0.1996
116	L	H	0.0733
117	V	H	0.0000
118	T	H	0.0000
119	V	H	0.0000
120	S	H	-0.6960
121	S	H	-0.6019
122	A	H	-0.4491
123	S	H	-0.6341
124	T	H	-0.9142
125	K	H	-1.6330
126	G	H	-1.7095
127	P	H	0.0000
128	S	H	-0.1449
129	V	H	0.0000
130	F	H	1.2773
131	P	H	0.5707
132	L	H	0.9093
133	A	H	0.3197
134	P	H	-0.1940
135	S	H	-0.7477
136	S	H	-1.1964
137	K	H	-1.9140
138	S	H	-1.0629
139	T	H	-1.0676
140	S	H	-0.9532
141	G	H	-0.7748
142	G	H	-0.8277
143	T	H	-0.5770
144	A	H	0.0000
145	A	H	-0.1599
146	L	H	0.0000
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.7302
150	V	H	0.0000
151	K	H	-0.2906
152	D	H	-0.9149
153	Y	H	0.0000
154	F	H	0.0000
155	P	H	0.0000
156	E	H	-0.3040
157	P	H	-0.5275
158	V	H	-0.5258
159	T	H	-0.4640
160	V	H	-0.2831
161	S	H	-0.4151
162	W	H	0.0000
163	N	H	-0.7909
164	S	H	-0.6695
165	G	H	-0.5346
166	A	H	-0.2789
167	L	H	-0.0444
168	T	H	-0.3234
169	S	H	-0.3769
170	G	H	-0.4781
171	V	H	-0.0332
172	H	H	-0.4686
173	T	H	0.1749
174	F	H	0.9336
175	P	H	0.7082
176	A	H	1.2441
177	V	H	2.4086
178	L	H	1.9302
179	Q	H	0.5667
180	S	H	0.0314
181	S	H	-0.2874
182	G	H	0.1199
183	L	H	0.0969
184	Y	H	0.6155
185	S	H	0.0000
186	L	H	0.0000
187	S	H	0.6547
188	S	H	0.0000
189	V	H	0.3919
190	V	H	0.0000
191	T	H	-0.2515
192	V	H	0.0000
193	P	H	-0.5630
194	S	H	-0.4916
195	S	H	-0.5226
196	S	H	-0.5112
197	L	H	-0.1766
198	G	H	-0.6047
199	T	H	-0.6916
200	Q	H	-1.0370
201	T	H	-0.6794
202	Y	H	0.0000
203	I	H	-0.8928
204	C	H	0.0000
205	N	H	-1.4423
206	V	H	0.0000
207	N	H	-1.7049
208	H	H	0.0000
209	K	H	-2.7197
210	P	H	-1.6151
211	S	H	-1.9031
212	N	H	-2.6277
213	T	H	-2.1006
214	K	H	-2.6257
215	V	H	-1.5920
216	D	H	-2.4780
217	K	H	-1.6519
218	K	H	-1.7012
219	V	H	-0.1763