Project name: DIBS_3sov_full

Chain sequence(s)	A: APLLLYANRRRDLRLVDATNGKENATIVVGGLEDAAAVDFVFSHGLIYWSDVSEEAIKRTEFNKTESVQNVVVVSGLLSPDGLLACDWLGEKLLYWTDSEETNRRIEEVSNLDGSLRKVLFWQELDQPRAIALDPSSSGFMMYWTDWGEVPKIERAGMDGSSSRFFIIINSEIYWPNGLTLLDYEEQKLYWADAKLNFIHKSNLDGTNRQQAVVKGSLPHPFALTLFEDDILYWTDWSTHSILACNKYTGEGLLRREIIHSDIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKD; Z: LPNAIIGR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6365
• Maximal score value: 1.7391
• Average score: -0.5423
• Total score value: -169.7474

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
20	A	A	-0.4482
21	P	A	0.0000
22	L	A	0.2062
23	L	A	0.0000
24	L	A	0.0000
25	Y	A	0.0000
26	A	A	0.0000
27	N	A	0.0000
28	R	A	-1.5293
29	R	A	-2.0861
30	D	A	0.0000
31	L	A	0.0000
32	R	A	0.2931
33	L	A	0.2992
34	V	A	0.0000
35	D	A	-1.5189
36	A	A	-0.8576
37	T	A	-0.9733
38	N	A	-2.1058
39	G	A	-2.4788
40	K	A	-3.6072
41	E	A	-3.6365
42	N	A	-2.8143
43	A	A	-1.0757
44	T	A	0.2490
45	I	A	1.5813
46	V	A	1.2677
47	V	A	0.0000
48	G	A	-0.6302
49	G	A	-1.5162
50	L	A	0.0000
51	E	A	-3.0936
52	D	A	0.0000
53	A	A	0.0000
54	A	A	0.0000
55	A	A	0.0000
56	V	A	0.0000
57	D	A	0.0000
58	F	A	0.0000
59	V	A	0.0000
60	F	A	-0.4769
61	S	A	-0.6828
62	H	A	-0.7985
63	G	A	0.0000
64	L	A	0.0000
65	I	A	0.0000
66	Y	A	0.0000
67	W	A	0.0000
68	S	A	0.0000
69	D	A	0.0000
70	V	A	0.0000
71	S	A	-1.9155
72	E	A	-2.1620
73	E	A	-1.5578
74	A	A	0.0000
75	I	A	0.0000
76	K	A	0.0000
77	R	A	-0.3730
78	T	A	0.0000
79	E	A	-1.6199
80	F	A	-1.1107
81	N	A	-2.3588
82	K	A	-2.7111
83	T	A	-1.9188
84	E	A	-2.1077
85	S	A	-1.1086
86	V	A	0.6955
87	Q	A	-0.0764
88	N	A	-0.0053
89	V	A	0.6689
90	V	A	-0.1013
91	V	A	0.0000
92	S	A	-0.4589
93	G	A	-0.7653
94	L	A	0.0000
95	L	A	0.0007
96	S	A	-0.5537
97	P	A	0.0000
98	D	A	0.0000
99	G	A	0.0000
100	L	A	0.0000
101	A	A	0.0000
102	C	A	0.0000
103	D	A	0.0000
104	W	A	-0.4724
105	L	A	0.0000
106	G	A	0.0000
107	E	A	-1.2296
108	K	A	0.0000
109	L	A	0.0000
110	Y	A	0.0000
111	W	A	0.0000
112	T	A	0.0000
113	D	A	0.0000
114	S	A	-1.2732
115	E	A	-1.9237
116	T	A	-0.9273
117	N	A	-1.6294
118	R	A	-1.1185
119	I	A	0.0000
120	E	A	0.0000
121	V	A	0.0000
122	S	A	0.0000
123	N	A	-1.3455
124	L	A	0.0000
125	D	A	-1.8197
126	G	A	0.0000
127	S	A	-1.0585
128	L	A	-0.9051
129	R	A	-1.6852
130	K	A	-0.9874
131	V	A	-0.3033
132	L	A	0.0000
133	F	A	0.0000
134	W	A	-0.1821
135	Q	A	-1.8263
136	E	A	-2.3189
137	L	A	0.0000
138	D	A	-2.2625
139	Q	A	-1.5054
140	P	A	0.0000
141	R	A	0.0000
142	A	A	-0.0391
143	I	A	0.0000
144	A	A	0.0210
145	L	A	0.0000
146	D	A	0.0000
147	P	A	0.0000
148	S	A	-0.1952
149	S	A	0.3719
150	G	A	0.0000
151	F	A	0.2668
152	M	A	0.0000
153	Y	A	0.0000
154	W	A	0.0000
155	T	A	0.0000
156	D	A	0.0000
157	W	A	-0.0114
158	G	A	-0.6390
159	E	A	-1.1179
160	V	A	0.3242
161	P	A	-0.0589
162	K	A	0.0000
163	I	A	0.0000
164	E	A	0.0000
165	R	A	0.2331
166	A	A	0.0000
167	G	A	0.0000
168	M	A	0.0000
169	D	A	-0.2467
170	G	A	-0.4596
171	S	A	-0.0737
172	S	A	-0.0508
173	R	A	0.4150
174	F	A	1.7391
175	I	A	0.9963
176	I	A	0.0000
177	I	A	0.0000
178	N	A	-1.2048
179	S	A	-1.3746
180	E	A	-1.8641
181	I	A	0.0000
182	Y	A	0.3546
183	W	A	0.1589
184	P	A	0.0000
185	N	A	0.0000
186	G	A	0.0000
187	L	A	0.0000
188	T	A	0.0000
189	L	A	0.0000
190	D	A	0.0000
191	Y	A	-1.3866
192	E	A	-2.8055
193	E	A	-2.4508
194	Q	A	-2.0928
195	K	A	-1.8537
196	L	A	0.0000
197	Y	A	0.0000
198	W	A	0.0000
199	A	A	0.0000
200	D	A	0.0000
201	A	A	0.0000
202	K	A	-0.6557
203	L	A	-0.4963
204	N	A	-0.8444
205	F	A	0.0000
206	I	A	0.0000
207	H	A	0.0000
208	K	A	-0.9314
209	S	A	0.0000
210	N	A	-1.6935
211	L	A	-1.1548
212	D	A	-1.0530
213	G	A	-1.1763
214	T	A	-1.4176
215	N	A	-2.0822
216	R	A	-1.9061
217	Q	A	-1.9094
218	A	A	-1.1524
219	V	A	0.0000
220	V	A	0.0000
221	K	A	-1.9623
222	G	A	-1.1252
223	S	A	-0.7319
224	L	A	0.0000
225	P	A	-0.5661
226	H	A	-0.5326
227	P	A	0.0000
228	F	A	0.0000
229	A	A	0.0000
230	L	A	0.0000
231	T	A	0.0000
232	L	A	0.0000
233	F	A	-1.0561
234	E	A	-2.7134
235	D	A	-1.9243
236	I	A	-0.8718
237	L	A	0.0000
238	Y	A	0.0000
239	W	A	0.0000
240	T	A	0.0000
241	D	A	0.0000
242	W	A	0.0172
243	S	A	-0.3853
244	T	A	-0.9077
245	H	A	-0.7320
246	S	A	0.0000
247	I	A	0.0000
248	L	A	0.0000
249	A	A	0.0000
250	C	A	0.0000
251	N	A	-1.0491
252	K	A	0.0000
253	Y	A	0.2147
254	T	A	-0.5422
255	G	A	0.0000
256	E	A	-1.7339
257	G	A	-1.3135
258	L	A	-0.5569
259	R	A	-1.6690
260	E	A	-2.2524
261	I	A	-1.4253
262	H	A	0.0000
263	S	A	-1.9337
264	D	A	-1.9137
265	I	A	0.0000
266	F	A	0.8150
267	S	A	0.1414
268	P	A	0.0000
269	M	A	0.0000
270	D	A	-0.3133
271	I	A	0.0000
272	H	A	-0.0690
273	A	A	0.0000
274	F	A	-0.1341
275	S	A	-0.8506
276	Q	A	-2.0091
277	Q	A	-2.2681
278	R	A	-1.6886
279	Q	A	-1.2634
280	P	A	-1.5607
281	N	A	-1.8142
282	A	A	-0.7938
283	T	A	-0.6082
284	N	A	-0.3661
285	P	A	-0.1443
286	C	A	0.0000
287	G	A	-0.3138
288	I	A	0.6320
289	D	A	-1.3926
290	N	A	-1.3270
291	G	A	-0.9598
292	G	A	-1.1868
293	C	A	0.0000
294	S	A	-1.1912
295	H	A	-0.4641
296	L	A	0.0000
297	C	A	0.0000
298	L	A	0.0000
299	M	A	0.0000
300	S	A	0.0000
301	P	A	0.7267
302	V	A	1.2719
303	K	A	-0.4679
304	P	A	-0.1716
305	F	A	0.8619
306	Y	A	0.2058
307	Q	A	-0.3843
308	C	A	0.0000
309	A	A	0.0000
310	C	A	0.0000
311	P	A	-0.7169
312	T	A	-0.7259
313	G	A	-0.4901
314	V	A	-0.8135
315	K	A	-2.0999
316	L	A	-1.6208
317	L	A	-1.8921
318	E	A	-2.6871
319	N	A	-2.2384
320	G	A	-1.7596
321	K	A	-1.6984
322	T	A	-1.7934
323	C	A	0.0000
324	K	A	-2.9454
325	D	A	-2.6447
38	L	Z	1.4509
39	P	Z	0.4186
40	N	Z	0.0000
41	A	Z	0.3318
42	I	Z	0.0007
43	G	Z	-0.6839
44	R	Z	-2.1204