| Chain sequence(s) |
A: ARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITSLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ B: ARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITSLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
| Mutated residues | SA370N |
| Energy difference between WT (input) and mutated protein (by FoldX) | 0.75183 kcal/mol
Changes in protein stability upon mutation are calculated using the FoldX forcefield. Computational prediction of protein stability is used with the intention of preventing the experimental characterization of proteins bearing mutations that significantly destabilize their structure. Mutations resulting in a predicted reduction in protein stability ≥ 1 kcal/mol are considered disruptive. |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | A | A | -1.5534 | |
| 2 | R | A | -1.9870 | |
| 3 | P | A | -1.2935 | |
| 4 | C | A | -0.5281 | |
| 5 | I | A | 0.6466 | |
| 6 | P | A | -0.3463 | |
| 7 | K | A | -0.7886 | |
| 8 | S | A | -0.4457 | |
| 9 | F | A | 0.1904 | |
| 10 | G | A | -0.1992 | |
| 11 | Y | A | 0.0225 | |
| 12 | S | A | -0.4496 | |
| 13 | S | A | 0.0000 | |
| 14 | V | A | -0.3723 | |
| 15 | V | A | 0.0000 | |
| 16 | C | A | 0.0000 | |
| 17 | V | A | 0.1862 | |
| 18 | C | A | 0.0000 | |
| 19 | N | A | -0.9030 | |
| 20 | A | A | -0.4989 | |
| 21 | T | A | -0.1775 | |
| 22 | Y | A | -0.1498 | |
| 23 | C | A | 0.0000 | |
| 24 | D | A | -0.6321 | |
| 25 | S | A | -1.2897 | |
| 26 | F | A | -1.4663 | |
| 27 | D | A | -1.9120 | |
| 28 | P | A | -1.2596 | |
| 29 | P | A | -0.6649 | |
| 30 | T | A | 0.0729 | |
| 31 | F | A | 0.7087 | |
| 32 | P | A | 0.0000 | |
| 33 | A | A | 0.0000 | |
| 34 | L | A | 0.2545 | |
| 35 | G | A | -0.2850 | |
| 36 | T | A | 0.0000 | |
| 37 | F | A | 0.0000 | |
| 38 | S | A | 0.0000 | |
| 39 | R | A | -0.2803 | |
| 40 | Y | A | 0.0000 | |
| 41 | E | A | 0.0000 | |
| 42 | S | A | 0.0000 | |
| 43 | T | A | 0.0000 | |
| 44 | R | A | -1.4033 | |
| 45 | S | A | -1.0621 | |
| 46 | G | A | -1.4864 | |
| 47 | R | A | -2.4992 | |
| 48 | R | A | 0.0000 | |
| 49 | M | A | 0.0000 | |
| 50 | E | A | -1.9224 | |
| 51 | L | A | -0.1815 | |
| 52 | S | A | -0.2116 | |
| 53 | M | A | 0.1060 | |
| 54 | G | A | 0.0000 | |
| 55 | P | A | -0.6299 | |
| 56 | I | A | 0.0000 | |
| 57 | Q | A | -1.7285 | |
| 58 | A | A | -1.2264 | |
| 59 | N | A | -1.8394 | |
| 60 | H | A | -1.3639 | |
| 61 | T | A | -0.8572 | |
| 62 | G | A | -0.4672 | |
| 63 | T | A | -0.3572 | |
| 64 | G | A | -0.4603 | |
| 65 | L | A | 0.0000 | |
| 66 | L | A | -0.0538 | |
| 67 | L | A | 0.0000 | |
| 68 | T | A | 0.3320 | |
| 69 | L | A | 0.0000 | |
| 70 | Q | A | -1.2267 | |
| 71 | P | A | 0.0000 | |
| 72 | E | A | -2.8602 | |
| 73 | Q | A | -2.7261 | |
| 74 | K | A | -2.7620 | |
| 75 | F | A | -1.2725 | |
| 76 | Q | A | -1.1125 | |
| 77 | K | A | -2.3283 | |
| 78 | V | A | 0.0000 | |
| 79 | K | A | -1.1376 | |
| 80 | G | A | 0.0000 | |
| 81 | F | A | 0.0000 | |
| 82 | G | A | 0.0000 | |
| 83 | G | A | 0.0000 | |
| 84 | A | A | 0.0000 | |
| 85 | M | A | 0.0000 | |
| 86 | T | A | 0.0000 | |
| 87 | D | A | 0.0000 | |
| 88 | A | A | 0.0000 | |
| 89 | A | A | 0.0000 | |
| 90 | A | A | 0.0000 | |
| 91 | L | A | 0.7692 | |
| 92 | N | A | 0.0000 | |
| 93 | I | A | 0.0000 | |
| 94 | L | A | 0.8073 | |
| 95 | A | A | 0.7549 | |
| 96 | L | A | 0.0000 | |
| 97 | S | A | -0.1645 | |
| 98 | P | A | -0.3841 | |
| 99 | P | A | -0.4979 | |
| 100 | A | A | 0.0000 | |
| 101 | Q | A | 0.0000 | |
| 102 | N | A | -0.6879 | |
| 103 | L | A | -0.3648 | |
| 104 | L | A | 0.0000 | |
| 105 | L | A | 0.0000 | |
| 106 | K | A | -1.0860 | |
| 107 | S | A | 0.0000 | |
| 108 | Y | A | 0.0000 | |
| 109 | F | A | 0.0000 | |
| 110 | S | A | 0.0000 | |
| 111 | E | A | -1.8336 | |
| 112 | E | A | -1.8950 | |
| 113 | G | A | 0.0000 | |
| 114 | I | A | 0.0000 | |
| 115 | G | A | 0.0000 | |
| 116 | Y | A | 0.0000 | |
| 117 | N | A | 0.0000 | |
| 118 | I | A | 0.0000 | |
| 119 | I | A | 0.0000 | |
| 120 | R | A | 0.0000 | |
| 121 | V | A | 0.0000 | |
| 122 | P | A | 0.0000 | |
| 123 | M | A | 0.0000 | |
| 124 | A | A | 0.0000 | |
| 125 | S | A | 0.0000 | |
| 126 | C | A | 0.0000 | |
| 127 | D | A | 0.0000 | |
| 128 | F | A | 0.0000 | |
| 129 | S | A | 0.0000 | |
| 130 | I | A | 1.6508 | |
| 131 | R | A | 0.0622 | |
| 132 | T | A | 0.0479 | |
| 133 | Y | A | 0.0000 | |
| 134 | T | A | 0.0000 | |
| 135 | Y | A | 0.0000 | |
| 136 | A | A | 0.0000 | |
| 137 | D | A | -2.2282 | |
| 138 | T | A | -1.6733 | |
| 139 | P | A | -1.6767 | |
| 140 | D | A | -2.2282 | |
| 141 | D | A | -1.8928 | |
| 142 | F | A | -0.9148 | |
| 143 | Q | A | -1.6146 | |
| 144 | L | A | 0.0000 | |
| 145 | H | A | -1.6796 | |
| 146 | N | A | -1.6918 | |
| 147 | F | A | -1.1041 | |
| 148 | S | A | -0.8437 | |
| 149 | L | A | -0.5221 | |
| 150 | P | A | -1.0871 | |
| 151 | E | A | -2.3281 | |
| 152 | E | A | 0.0000 | |
| 153 | D | A | 0.0000 | |
| 154 | T | A | -1.4813 | |
| 155 | K | A | -2.1918 | |
| 156 | L | A | -0.8288 | |
| 157 | K | A | 0.0000 | |
| 158 | I | A | 0.0000 | |
| 159 | P | A | -0.7049 | |
| 160 | L | A | 0.0000 | |
| 161 | I | A | 0.0000 | |
| 162 | H | A | -0.9221 | |
| 163 | R | A | -0.9749 | |
| 164 | A | A | 0.0000 | |
| 165 | L | A | -0.3444 | |
| 166 | Q | A | -1.1841 | |
| 167 | L | A | -0.8067 | |
| 168 | A | A | -0.9044 | |
| 169 | Q | A | -1.4761 | |
| 170 | R | A | -1.1323 | |
| 171 | P | A | -0.7014 | |
| 172 | V | A | -0.2245 | |
| 173 | S | A | -0.1126 | |
| 174 | L | A | 0.0000 | |
| 175 | L | A | 0.0000 | |
| 176 | A | A | 0.0000 | |
| 177 | S | A | 0.0000 | |
| 178 | P | A | 0.0000 | |
| 179 | W | A | 0.0000 | |
| 180 | T | A | 0.0000 | |
| 181 | S | A | 0.0000 | |
| 182 | P | A | 0.0000 | |
| 183 | T | A | -0.6807 | |
| 184 | W | A | -0.9317 | |
| 185 | L | A | 0.0000 | |
| 186 | K | A | 0.0000 | |
| 187 | T | A | -1.3465 | |
| 188 | N | A | -1.9581 | |
| 189 | G | A | -1.1089 | |
| 190 | A | A | -0.7713 | |
| 191 | V | A | -0.2463 | |
| 192 | N | A | -0.7266 | |
| 193 | G | A | -1.0231 | |
| 194 | K | A | -1.5951 | |
| 195 | G | A | 0.0000 | |
| 196 | S | A | -0.9402 | |
| 197 | L | A | 0.0000 | |
| 198 | K | A | -1.1889 | |
| 199 | G | A | -1.2474 | |
| 200 | Q | A | -1.7013 | |
| 201 | P | A | -1.5683 | |
| 202 | G | A | -1.1952 | |
| 203 | D | A | -0.7229 | |
| 204 | I | A | 0.6762 | |
| 205 | Y | A | 0.2252 | |
| 206 | H | A | 0.0000 | |
| 207 | Q | A | -0.6845 | |
| 208 | T | A | 0.0000 | |
| 209 | W | A | 0.0000 | |
| 210 | A | A | 0.0000 | |
| 211 | R | A | -0.9217 | |
| 212 | Y | A | 0.0000 | |
| 213 | F | A | 0.0000 | |
| 214 | V | A | -0.8571 | |
| 215 | K | A | -1.1358 | |
| 216 | F | A | 0.0000 | |
| 217 | L | A | 0.0000 | |
| 218 | D | A | -2.4302 | |
| 219 | A | A | -1.6466 | |
| 220 | Y | A | 0.0000 | |
| 221 | A | A | -2.6388 | |
| 222 | E | A | -3.0878 | |
| 223 | H | A | -2.5374 | |
| 224 | K | A | -3.0050 | |
| 225 | L | A | 0.0000 | |
| 226 | Q | A | -2.1267 | |
| 227 | F | A | 0.0000 | |
| 228 | W | A | -0.5593 | |
| 229 | A | A | 0.0000 | |
| 230 | V | A | 0.0000 | |
| 231 | T | A | 0.0000 | |
| 232 | A | A | 0.0000 | |
| 233 | E | A | 0.0000 | |
| 234 | N | A | 0.0000 | |
| 235 | E | A | 0.0000 | |
| 236 | P | A | 0.0000 | |
| 237 | S | A | 0.1541 | |
| 238 | A | A | 0.0000 | |
| 239 | G | A | 0.0000 | |
| 240 | L | A | 0.3655 | |
| 241 | L | A | 0.8174 | |
| 242 | S | A | -0.3984 | |
| 243 | G | A | -0.6040 | |
| 244 | Y | A | -0.0964 | |
| 245 | P | A | -0.2023 | |
| 246 | F | A | 0.0635 | |
| 247 | Q | A | 0.0000 | |
| 248 | C | A | 0.0000 | |
| 249 | L | A | 0.0000 | |
| 250 | G | A | 0.0000 | |
| 251 | F | A | 0.0000 | |
| 252 | T | A | -0.5958 | |
| 253 | P | A | -1.1369 | |
| 254 | E | A | -1.7254 | |
| 255 | H | A | -1.3251 | |
| 256 | Q | A | 0.0000 | |
| 257 | R | A | -1.7297 | |
| 258 | D | A | -2.2284 | |
| 259 | F | A | 0.0000 | |
| 260 | I | A | 0.0000 | |
| 261 | A | A | -2.1080 | |
| 262 | R | A | -2.5444 | |
| 263 | D | A | 0.0000 | |
| 264 | L | A | 0.0000 | |
| 265 | G | A | 0.0000 | |
| 266 | P | A | -0.9195 | |
| 267 | T | A | -1.0327 | |
| 268 | L | A | 0.0000 | |
| 269 | A | A | -1.2902 | |
| 270 | N | A | -1.5237 | |
| 271 | S | A | -1.3237 | |
| 272 | T | A | -1.0360 | |
| 273 | H | A | 0.0000 | |
| 274 | H | A | -2.0592 | |
| 275 | N | A | -2.0888 | |
| 276 | V | A | 0.0000 | |
| 277 | R | A | -1.4451 | |
| 278 | L | A | 0.0000 | |
| 279 | L | A | 0.0000 | |
| 280 | M | A | 0.0000 | |
| 281 | L | A | 0.0000 | |
| 282 | D | A | 0.0000 | |
| 283 | D | A | 0.0000 | |
| 284 | Q | A | 0.0528 | |
| 285 | R | A | 0.0000 | |
| 286 | L | A | 1.5333 | |
| 287 | L | A | 0.6423 | |
| 288 | L | A | 0.0000 | |
| 289 | P | A | -0.6559 | |
| 290 | H | A | -1.0559 | |
| 291 | W | A | 0.0000 | |
| 292 | A | A | 0.0000 | |
| 293 | K | A | -1.1584 | |
| 294 | V | A | -1.0870 | |
| 295 | V | A | 0.0000 | |
| 296 | L | A | 0.0000 | |
| 297 | T | A | -0.7585 | |
| 298 | D | A | -1.6032 | |
| 299 | P | A | -1.7875 | |
| 300 | E | A | -2.9205 | |
| 301 | A | A | 0.0000 | |
| 302 | A | A | -1.6433 | |
| 303 | K | A | -2.3087 | |
| 304 | Y | A | -1.2349 | |
| 305 | V | A | 0.0000 | |
| 306 | H | A | -1.2006 | |
| 307 | G | A | 0.0000 | |
| 308 | I | A | 0.0000 | |
| 309 | A | A | 0.0000 | |
| 310 | V | A | 0.0000 | |
| 311 | H | A | 0.0000 | |
| 312 | W | A | 0.0000 | |
| 313 | Y | A | 0.8026 | |
| 314 | L | A | 0.0000 | |
| 315 | D | A | 0.7828 | |
| 316 | F | A | 2.5130 | |
| 317 | L | A | 2.5692 | |
| 318 | A | A | 0.0000 | |
| 319 | P | A | -0.1393 | |
| 320 | A | A | -0.5196 | |
| 321 | K | A | -2.0386 | |
| 322 | A | A | -0.8549 | |
| 323 | T | A | 0.0000 | |
| 324 | L | A | 0.0000 | |
| 325 | G | A | -1.5156 | |
| 326 | E | A | -1.6601 | |
| 327 | T | A | 0.0000 | |
| 328 | H | A | -1.5225 | |
| 329 | R | A | -2.1783 | |
| 330 | L | A | -0.7245 | |
| 331 | F | A | -0.7978 | |
| 332 | P | A | -1.3085 | |
| 333 | N | A | -1.5266 | |
| 334 | T | A | -0.8322 | |
| 335 | M | A | -0.4861 | |
| 336 | L | A | 0.0000 | |
| 337 | F | A | 0.0000 | |
| 338 | A | A | 0.0000 | |
| 339 | S | A | 0.0000 | |
| 340 | E | A | 0.0000 | |
| 341 | A | A | 0.0000 | |
| 342 | C | A | 0.0000 | |
| 343 | V | A | 0.0000 | |
| 344 | G | A | 0.0000 | |
| 345 | S | A | -0.0876 | |
| 346 | K | A | 0.3145 | |
| 347 | F | A | 1.8006 | |
| 348 | W | A | 1.4102 | |
| 349 | E | A | -0.0777 | |
| 350 | Q | A | -1.3634 | |
| 351 | S | A | -1.2985 | |
| 352 | V | A | 0.0000 | |
| 353 | R | A | -1.0099 | |
| 354 | L | A | 0.0000 | |
| 355 | G | A | 0.0000 | |
| 356 | S | A | 0.0000 | |
| 357 | W | A | 0.0000 | |
| 358 | D | A | -1.4083 | |
| 359 | R | A | 0.0000 | |
| 360 | G | A | 0.0000 | |
| 361 | M | A | 0.0000 | |
| 362 | Q | A | -0.9087 | |
| 363 | Y | A | 0.0000 | |
| 364 | S | A | 0.0000 | |
| 365 | H | A | -0.6939 | |
| 366 | S | A | 0.0000 | |
| 367 | I | A | 0.0000 | |
| 368 | I | A | 0.0000 | |
| 369 | T | A | 0.0470 | |
| 370 | N | A | 0.0000 | mutated: SA370N |
| 371 | L | A | 0.0000 | |
| 372 | L | A | 0.4569 | |
| 373 | Y | A | 0.0285 | |
| 374 | H | A | -0.1672 | |
| 375 | V | A | 0.0000 | |
| 376 | V | A | -0.5735 | |
| 377 | G | A | 0.0000 | |
| 378 | W | A | 0.0000 | |
| 379 | T | A | 0.0000 | |
| 380 | D | A | 0.0000 | |
| 381 | W | A | 0.0000 | |
| 382 | N | A | 0.0000 | |
| 383 | L | A | 0.0000 | |
| 384 | A | A | 0.0000 | |
| 385 | L | A | 0.0000 | |
| 386 | N | A | -0.5895 | |
| 387 | P | A | -1.0652 | |
| 388 | E | A | -2.5806 | |
| 389 | G | A | 0.0000 | |
| 390 | G | A | 0.0000 | |
| 391 | P | A | -0.3082 | |
| 392 | N | A | -0.4944 | |
| 393 | W | A | 0.3890 | |
| 394 | V | A | -0.1354 | |
| 395 | R | A | -2.1661 | |
| 396 | N | A | -2.3211 | |
| 397 | F | A | -1.0756 | |
| 398 | V | A | 0.0000 | |
| 399 | D | A | 0.0000 | |
| 400 | S | A | 0.0000 | |
| 401 | P | A | 0.0000 | |
| 402 | I | A | 0.0000 | |
| 403 | I | A | 0.0000 | |
| 404 | V | A | 0.0000 | |
| 405 | D | A | -0.2134 | |
| 406 | I | A | 1.1494 | |
| 407 | T | A | -0.1505 | |
| 408 | K | A | -1.5158 | |
| 409 | D | A | -0.8640 | |
| 410 | T | A | 0.0000 | |
| 411 | F | A | 0.0000 | |
| 412 | Y | A | 0.0000 | |
| 413 | K | A | 0.0000 | |
| 414 | Q | A | 0.0000 | |
| 415 | P | A | 0.0000 | |
| 416 | M | A | 0.0000 | |
| 417 | F | A | 0.0000 | |
| 418 | Y | A | 0.0000 | |
| 419 | H | A | 0.0000 | |
| 420 | L | A | 0.0000 | |
| 421 | G | A | 0.0000 | |
| 422 | H | A | 0.0000 | |
| 423 | F | A | 0.0000 | |
| 424 | S | A | 0.0000 | |
| 425 | K | A | 0.0000 | |
| 426 | F | A | 0.0000 | |
| 427 | I | A | 0.0000 | |
| 428 | P | A | -1.0790 | |
| 429 | E | A | -2.0222 | |
| 430 | G | A | -1.7479 | |
| 431 | S | A | 0.0000 | |
| 432 | Q | A | -1.5813 | |
| 433 | R | A | -1.0508 | |
| 434 | V | A | 0.0000 | |
| 435 | G | A | 0.0000 | |
| 436 | L | A | 0.5999 | |
| 437 | V | A | 1.2021 | |
| 438 | A | A | -0.0645 | |
| 439 | S | A | -0.6765 | |
| 440 | Q | A | -1.9036 | |
| 441 | K | A | -2.8535 | |
| 442 | N | A | -2.5864 | |
| 443 | D | A | -2.7828 | |
| 444 | L | A | 0.0000 | |
| 445 | D | A | -1.0489 | |
| 446 | A | A | -0.1451 | |
| 447 | V | A | 0.0000 | |
| 448 | A | A | 0.0000 | |
| 449 | L | A | 0.0000 | |
| 450 | M | A | -0.8747 | |
| 451 | H | A | -1.3743 | |
| 452 | P | A | -1.6932 | |
| 453 | D | A | -2.1082 | |
| 454 | G | A | -1.4508 | |
| 455 | S | A | 0.0000 | |
| 456 | A | A | 0.0000 | |
| 457 | V | A | 0.0000 | |
| 458 | V | A | 0.0000 | |
| 459 | V | A | 0.0000 | |
| 460 | V | A | 0.0000 | |
| 461 | L | A | 0.0000 | |
| 462 | N | A | 0.0000 | |
| 463 | R | A | -1.5974 | |
| 464 | S | A | -1.5875 | |
| 465 | S | A | -1.5474 | |
| 466 | K | A | -2.9777 | |
| 467 | D | A | -2.4269 | |
| 468 | V | A | 0.0000 | |
| 469 | P | A | -0.3024 | |
| 470 | L | A | 0.0000 | |
| 471 | T | A | 0.0000 | |
| 472 | I | A | 0.0000 | |
| 473 | K | A | -0.3464 | |
| 474 | D | A | 0.0000 | |
| 475 | P | A | -0.3246 | |
| 476 | A | A | -0.2582 | |
| 477 | V | A | -0.2902 | |
| 478 | G | A | -0.7073 | |
| 479 | F | A | -0.7863 | |
| 480 | L | A | 0.0000 | |
| 481 | E | A | -0.6595 | |
| 482 | T | A | 0.0000 | |
| 483 | I | A | 0.8985 | |
| 484 | S | A | 0.0000 | |
| 485 | P | A | -1.0338 | |
| 486 | G | A | -1.5408 | |
| 487 | Y | A | -1.0231 | |
| 488 | S | A | 0.0000 | |
| 489 | I | A | 0.0000 | |
| 490 | H | A | 0.0000 | |
| 491 | T | A | 0.0000 | |
| 492 | Y | A | 0.0000 | |
| 493 | L | A | 0.0947 | |
| 494 | W | A | 0.0000 | |
| 495 | R | A | -0.8201 | |
| 496 | R | A | -1.0629 | |
| 497 | Q | A | -1.2540 | |
| 1 | A | B | -1.4532 | |
| 2 | R | B | -1.6717 | |
| 3 | P | B | -1.0013 | |
| 4 | C | B | -0.3233 | |
| 5 | I | B | 0.7029 | |
| 6 | P | B | -0.3665 | |
| 7 | K | B | -0.7955 | |
| 8 | S | B | -0.2957 | |
| 9 | F | B | 0.4646 | |
| 10 | G | B | -0.0343 | |
| 11 | Y | B | 0.2039 | |
| 12 | S | B | -0.3229 | |
| 13 | S | B | 0.0000 | |
| 14 | V | B | -0.2861 | |
| 15 | V | B | 0.0000 | |
| 16 | C | B | 0.0000 | |
| 17 | V | B | 0.1853 | |
| 18 | C | B | 0.0000 | |
| 19 | N | B | -0.8000 | |
| 20 | A | B | -0.4736 | |
| 21 | T | B | -0.1030 | |
| 22 | Y | B | -0.0307 | |
| 23 | C | B | 0.0000 | |
| 24 | D | B | 0.0000 | |
| 25 | S | B | -1.4119 | |
| 26 | F | B | -1.8001 | |
| 27 | D | B | -2.4653 | |
| 28 | P | B | -1.7501 | |
| 29 | P | B | -1.1235 | |
| 30 | T | B | -0.1476 | |
| 31 | F | B | 0.7866 | |
| 32 | P | B | 0.0000 | |
| 33 | A | B | 0.6745 | |
| 34 | L | B | 1.0052 | |
| 35 | G | B | 0.2325 | |
| 36 | T | B | 0.4355 | |
| 37 | F | B | 0.0000 | |
| 38 | S | B | 0.0000 | |
| 39 | R | B | 0.0734 | |
| 40 | Y | B | 0.0000 | |
| 41 | E | B | 0.0000 | |
| 42 | S | B | 0.0000 | |
| 43 | T | B | 0.0000 | |
| 44 | R | B | -1.4060 | |
| 45 | S | B | -1.0777 | |
| 46 | G | B | -1.4834 | |
| 47 | R | B | -2.3385 | |
| 48 | R | B | 0.0000 | |
| 49 | M | B | 0.0000 | |
| 50 | E | B | -1.1766 | |
| 51 | L | B | 0.1335 | |
| 52 | S | B | 0.4473 | |
| 53 | M | B | 0.8924 | |
| 54 | G | B | -0.0113 | |
| 55 | P | B | -0.1811 | |
| 56 | I | B | -0.3890 | |
| 57 | Q | B | -1.2212 | |
| 58 | A | B | -0.9172 | |
| 59 | N | B | -1.5681 | |
| 60 | H | B | -1.2865 | |
| 61 | T | B | -0.7681 | |
| 62 | G | B | -0.7021 | |
| 63 | T | B | -0.5478 | |
| 64 | G | B | -0.7537 | |
| 65 | L | B | 0.0000 | |
| 66 | L | B | -0.0629 | |
| 67 | L | B | 0.0000 | |
| 68 | T | B | 0.3337 | |
| 69 | L | B | 0.0000 | |
| 70 | Q | B | -1.4942 | |
| 71 | P | B | -1.9765 | |
| 72 | E | B | -3.0730 | |
| 73 | Q | B | -2.9643 | |
| 74 | K | B | -3.0524 | |
| 75 | F | B | -1.2617 | |
| 76 | Q | B | -1.0874 | |
| 77 | K | B | -2.3522 | |
| 78 | V | B | 0.0000 | |
| 79 | K | B | -1.1967 | |
| 80 | G | B | 0.0000 | |
| 81 | F | B | 0.0000 | |
| 82 | G | B | 0.0000 | |
| 83 | G | B | 0.0000 | |
| 84 | A | B | 0.0000 | |
| 85 | M | B | 0.0000 | |
| 86 | T | B | 0.0000 | |
| 87 | D | B | 0.0000 | |
| 88 | A | B | 0.0000 | |
| 89 | A | B | 0.0000 | |
| 90 | A | B | 0.0000 | |
| 91 | L | B | 0.4605 | |
| 92 | N | B | 0.0000 | |
| 93 | I | B | 0.0000 | |
| 94 | L | B | 0.3520 | |
| 95 | A | B | 0.3827 | |
| 96 | L | B | 0.0000 | |
| 97 | S | B | -0.2969 | |
| 98 | P | B | -0.4122 | |
| 99 | P | B | -0.5025 | |
| 100 | A | B | 0.0000 | |
| 101 | Q | B | 0.0000 | |
| 102 | N | B | -0.9278 | |
| 103 | L | B | -0.5476 | |
| 104 | L | B | 0.0000 | |
| 105 | L | B | 0.0000 | |
| 106 | K | B | -1.4075 | |
| 107 | S | B | 0.0000 | |
| 108 | Y | B | 0.0000 | |
| 109 | F | B | 0.0000 | |
| 110 | S | B | 0.0000 | |
| 111 | E | B | -2.4016 | |
| 112 | E | B | -2.2258 | |
| 113 | G | B | 0.0000 | |
| 114 | I | B | 0.0000 | |
| 115 | G | B | 0.0000 | |
| 116 | Y | B | 0.0000 | |
| 117 | N | B | 0.0000 | |
| 118 | I | B | 0.0000 | |
| 119 | I | B | 0.0000 | |
| 120 | R | B | 0.0000 | |
| 121 | V | B | 0.0000 | |
| 122 | P | B | 0.0000 | |
| 123 | M | B | 0.0000 | |
| 124 | A | B | 0.0000 | |
| 125 | S | B | 0.0000 | |
| 126 | C | B | 0.0000 | |
| 127 | D | B | 0.0000 | |
| 128 | F | B | 0.0000 | |
| 129 | S | B | 0.0000 | |
| 130 | I | B | 1.6446 | |
| 131 | R | B | -0.0586 | |
| 132 | T | B | -0.0536 | |
| 133 | Y | B | 0.0000 | |
| 134 | T | B | 0.0000 | |
| 135 | Y | B | 0.0000 | |
| 136 | A | B | 0.0000 | |
| 137 | D | B | -2.1390 | |
| 138 | T | B | -1.3650 | |
| 139 | P | B | -0.9270 | |
| 140 | D | B | -0.4304 | |
| 141 | D | B | 0.0000 | |
| 142 | F | B | 0.0000 | |
| 143 | Q | B | -0.8616 | |
| 144 | L | B | 0.0000 | |
| 145 | H | B | -1.4637 | |
| 146 | N | B | -2.0139 | |
| 147 | F | B | 0.0000 | |
| 148 | S | B | -1.0110 | |
| 149 | L | B | -0.7024 | |
| 150 | P | B | -1.2148 | |
| 151 | E | B | -2.4954 | |
| 152 | E | B | -1.3864 | |
| 153 | D | B | 0.0000 | |
| 154 | T | B | -1.6288 | |
| 155 | K | B | -2.3149 | |
| 156 | L | B | 0.0000 | |
| 157 | K | B | 0.0000 | |
| 158 | I | B | 0.0000 | |
| 159 | P | B | -0.8415 | |
| 160 | L | B | 0.0000 | |
| 161 | I | B | 0.0000 | |
| 162 | H | B | -1.1702 | |
| 163 | R | B | -1.2083 | |
| 164 | A | B | 0.0000 | |
| 165 | L | B | -0.5985 | |
| 166 | Q | B | -1.4271 | |
| 167 | L | B | -1.2063 | |
| 168 | A | B | -1.3112 | |
| 169 | Q | B | -1.7167 | |
| 170 | R | B | -1.3903 | |
| 171 | P | B | -0.9134 | |
| 172 | V | B | -0.3318 | |
| 173 | S | B | -0.1112 | |
| 174 | L | B | 0.0000 | |
| 175 | L | B | 0.0000 | |
| 176 | A | B | 0.0000 | |
| 177 | S | B | 0.0000 | |
| 178 | P | B | 0.0000 | |
| 179 | W | B | 0.0000 | |
| 180 | T | B | 0.0000 | |
| 181 | S | B | 0.0000 | |
| 182 | P | B | 0.0000 | |
| 183 | T | B | -0.6536 | |
| 184 | W | B | -0.6098 | |
| 185 | L | B | 0.0000 | |
| 186 | K | B | 0.0000 | |
| 187 | T | B | -1.0261 | |
| 188 | N | B | -1.3218 | |
| 189 | G | B | -0.8166 | |
| 190 | A | B | -0.5658 | |
| 191 | V | B | -0.1537 | |
| 192 | N | B | -0.6020 | |
| 193 | G | B | -0.8451 | |
| 194 | K | B | -1.2908 | |
| 195 | G | B | 0.0000 | |
| 196 | S | B | -0.7671 | |
| 197 | L | B | 0.0000 | |
| 198 | K | B | -1.2587 | |
| 199 | G | B | -1.5744 | |
| 200 | Q | B | -2.1104 | |
| 201 | P | B | -1.7500 | |
| 202 | G | B | -1.5410 | |
| 203 | D | B | -1.3389 | |
| 204 | I | B | -0.5253 | |
| 205 | Y | B | -0.5090 | |
| 206 | H | B | 0.0000 | |
| 207 | Q | B | -0.9523 | |
| 208 | T | B | 0.0000 | |
| 209 | W | B | 0.0000 | |
| 210 | A | B | 0.0000 | |
| 211 | R | B | -0.6865 | |
| 212 | Y | B | 0.0000 | |
| 213 | F | B | 0.0000 | |
| 214 | V | B | -0.5337 | |
| 215 | K | B | -0.8493 | |
| 216 | F | B | 0.0000 | |
| 217 | L | B | 0.0000 | |
| 218 | D | B | -1.7774 | |
| 219 | A | B | -1.5402 | |
| 220 | Y | B | 0.0000 | |
| 221 | A | B | -2.3189 | |
| 222 | E | B | -2.8862 | |
| 223 | H | B | -2.4043 | |
| 224 | K | B | -2.8899 | |
| 225 | L | B | 0.0000 | |
| 226 | Q | B | -1.9021 | |
| 227 | F | B | 0.0000 | |
| 228 | W | B | -0.5880 | |
| 229 | A | B | 0.0000 | |
| 230 | V | B | 0.0000 | |
| 231 | T | B | 0.0000 | |
| 232 | A | B | 0.0000 | |
| 233 | E | B | 0.0000 | |
| 234 | N | B | 0.0000 | |
| 235 | E | B | -0.2372 | |
| 236 | P | B | 0.0000 | |
| 237 | S | B | 0.1359 | |
| 238 | A | B | 0.0000 | |
| 239 | G | B | 0.0000 | |
| 240 | L | B | 0.4722 | |
| 241 | L | B | 0.8491 | |
| 242 | S | B | -0.2776 | |
| 243 | G | B | -0.5412 | |
| 244 | Y | B | -0.0887 | |
| 245 | P | B | -0.1446 | |
| 246 | F | B | 0.1491 | |
| 247 | Q | B | 0.0000 | |
| 248 | C | B | 0.0000 | |
| 249 | L | B | 0.0000 | |
| 250 | G | B | 0.0000 | |
| 251 | F | B | 0.0000 | |
| 252 | T | B | -0.5324 | |
| 253 | P | B | -1.0518 | |
| 254 | E | B | -1.6602 | |
| 255 | H | B | -1.2849 | |
| 256 | Q | B | 0.0000 | |
| 257 | R | B | -1.7537 | |
| 258 | D | B | -2.1582 | |
| 259 | F | B | 0.0000 | |
| 260 | I | B | 0.0000 | |
| 261 | A | B | 0.0000 | |
| 262 | R | B | -2.6605 | |
| 263 | D | B | 0.0000 | |
| 264 | L | B | 0.0000 | |
| 265 | G | B | 0.0000 | |
| 266 | P | B | -1.1281 | |
| 267 | T | B | -0.9958 | |
| 268 | L | B | 0.0000 | |
| 269 | A | B | -1.2285 | |
| 270 | N | B | -1.5498 | |
| 271 | S | B | -1.2650 | |
| 272 | T | B | -0.9511 | |
| 273 | H | B | 0.0000 | |
| 274 | H | B | -2.0796 | |
| 275 | N | B | -2.0161 | |
| 276 | V | B | 0.0000 | |
| 277 | R | B | -1.6079 | |
| 278 | L | B | 0.0000 | |
| 279 | L | B | 0.0000 | |
| 280 | M | B | 0.0000 | |
| 281 | L | B | 0.0000 | |
| 282 | D | B | 0.0000 | |
| 283 | D | B | 0.0000 | |
| 284 | Q | B | 0.1221 | |
| 285 | R | B | 0.0000 | |
| 286 | L | B | 1.5765 | |
| 287 | L | B | 0.6467 | |
| 288 | L | B | 0.0000 | |
| 289 | P | B | -0.7284 | |
| 290 | H | B | -0.8902 | |
| 291 | W | B | 0.0000 | |
| 292 | A | B | 0.0000 | |
| 293 | K | B | -0.9634 | |
| 294 | V | B | -0.8979 | |
| 295 | V | B | 0.0000 | |
| 296 | L | B | 0.0000 | |
| 297 | T | B | -0.6495 | |
| 298 | D | B | -1.5617 | |
| 299 | P | B | -1.6980 | |
| 300 | E | B | -2.6835 | |
| 301 | A | B | 0.0000 | |
| 302 | A | B | -1.5310 | |
| 303 | K | B | -2.2329 | |
| 304 | Y | B | -1.3362 | |
| 305 | V | B | 0.0000 | |
| 306 | H | B | -1.0720 | |
| 307 | G | B | 0.0000 | |
| 308 | I | B | 0.0000 | |
| 309 | A | B | 0.0000 | |
| 310 | V | B | 0.0000 | |
| 311 | H | B | 0.0000 | |
| 312 | W | B | 0.0000 | |
| 313 | Y | B | 0.5071 | |
| 314 | L | B | 0.0000 | |
| 315 | D | B | 0.0651 | |
| 316 | F | B | 1.4759 | |
| 317 | L | B | 2.1118 | |
| 318 | A | B | 1.0291 | |
| 319 | P | B | -0.1092 | |
| 320 | A | B | -0.5890 | |
| 321 | K | B | -2.1723 | |
| 322 | A | B | -1.0028 | |
| 323 | T | B | 0.0000 | |
| 324 | L | B | 0.0000 | |
| 325 | G | B | -1.7556 | |
| 326 | E | B | -2.2454 | |
| 327 | T | B | 0.0000 | |
| 328 | H | B | -1.8082 | |
| 329 | R | B | -2.5132 | |
| 330 | L | B | -1.0681 | |
| 331 | F | B | -0.9783 | |
| 332 | P | B | -1.4322 | |
| 333 | N | B | -1.5238 | |
| 334 | T | B | 0.0000 | |
| 335 | M | B | -0.5247 | |
| 336 | L | B | 0.0000 | |
| 337 | F | B | 0.0000 | |
| 338 | A | B | 0.0000 | |
| 339 | S | B | 0.0000 | |
| 340 | E | B | 0.0000 | |
| 341 | A | B | 0.0000 | |
| 342 | C | B | 0.0000 | |
| 343 | V | B | 0.0000 | |
| 344 | G | B | 0.0000 | |
| 345 | S | B | 0.0189 | |
| 346 | K | B | 0.4198 | |
| 347 | F | B | 1.8793 | |
| 348 | W | B | 1.4352 | |
| 349 | E | B | -0.2247 | |
| 350 | Q | B | -1.1166 | |
| 351 | S | B | -0.8186 | |
| 352 | V | B | -0.7902 | |
| 353 | R | B | -0.4928 | |
| 354 | L | B | 0.1380 | |
| 355 | G | B | 0.0000 | |
| 356 | S | B | 0.0000 | |
| 357 | W | B | 0.0000 | |
| 358 | D | B | -1.3843 | |
| 359 | R | B | 0.0000 | |
| 360 | G | B | 0.0000 | |
| 361 | M | B | 0.0000 | |
| 362 | Q | B | -0.9978 | |
| 363 | Y | B | 0.0000 | |
| 364 | S | B | 0.0000 | |
| 365 | H | B | -0.7360 | |
| 366 | S | B | -0.2857 | |
| 367 | I | B | 0.0000 | |
| 368 | I | B | 0.0000 | |
| 369 | T | B | -0.0914 | |
| 370 | S | B | 0.0000 | |
| 371 | L | B | 0.0000 | |
| 372 | L | B | 0.5296 | |
| 373 | Y | B | 0.0083 | |
| 374 | H | B | -0.0862 | |
| 375 | V | B | 0.0000 | |
| 376 | V | B | -0.5424 | |
| 377 | G | B | 0.0000 | |
| 378 | W | B | 0.0000 | |
| 379 | T | B | 0.0000 | |
| 380 | D | B | 0.0000 | |
| 381 | W | B | 0.0000 | |
| 382 | N | B | 0.0000 | |
| 383 | L | B | 0.0000 | |
| 384 | A | B | 0.0000 | |
| 385 | L | B | 0.0000 | |
| 386 | N | B | -0.7419 | |
| 387 | P | B | -1.0573 | |
| 388 | E | B | -2.2472 | |
| 389 | G | B | 0.0000 | |
| 390 | G | B | 0.0000 | |
| 391 | P | B | -0.1905 | |
| 392 | N | B | 0.0000 | |
| 393 | W | B | 0.3147 | |
| 394 | V | B | -0.2773 | |
| 395 | R | B | -1.9429 | |
| 396 | N | B | -1.1741 | |
| 397 | F | B | -1.0727 | |
| 398 | V | B | 0.0000 | |
| 399 | D | B | 0.0000 | |
| 400 | S | B | 0.0000 | |
| 401 | P | B | 0.0000 | |
| 402 | I | B | 0.0000 | |
| 403 | I | B | 0.0000 | |
| 404 | V | B | 0.0000 | |
| 405 | D | B | -0.6697 | |
| 406 | I | B | 0.0347 | |
| 407 | T | B | -0.6275 | |
| 408 | K | B | -1.7872 | |
| 409 | D | B | -1.1755 | |
| 410 | T | B | -0.8007 | |
| 411 | F | B | 0.0000 | |
| 412 | Y | B | 0.0000 | |
| 413 | K | B | 0.0000 | |
| 414 | Q | B | 0.0000 | |
| 415 | P | B | 0.0000 | |
| 416 | M | B | 0.0000 | |
| 417 | F | B | 0.0000 | |
| 418 | Y | B | 0.0000 | |
| 419 | H | B | 0.0000 | |
| 420 | L | B | 0.0000 | |
| 421 | G | B | 0.0000 | |
| 422 | H | B | 0.0000 | |
| 423 | F | B | 0.0000 | |
| 424 | S | B | 0.0000 | |
| 425 | K | B | 0.0000 | |
| 426 | F | B | 0.0000 | |
| 427 | I | B | 0.0000 | |
| 428 | P | B | -1.0717 | |
| 429 | E | B | -2.1821 | |
| 430 | G | B | -1.8247 | |
| 431 | S | B | 0.0000 | |
| 432 | Q | B | -1.8368 | |
| 433 | R | B | -1.0793 | |
| 434 | V | B | 0.0000 | |
| 435 | G | B | 0.0000 | |
| 436 | L | B | 0.7340 | |
| 437 | V | B | 1.7134 | |
| 438 | A | B | 0.2842 | |
| 439 | S | B | -0.5182 | |
| 440 | Q | B | -1.6037 | |
| 441 | K | B | -2.7017 | |
| 442 | N | B | -2.4154 | |
| 443 | D | B | -2.7226 | |
| 444 | L | B | -1.4546 | |
| 445 | D | B | -0.9949 | |
| 446 | A | B | -0.0558 | |
| 447 | V | B | 0.0000 | |
| 448 | A | B | 0.0000 | |
| 449 | L | B | 0.0000 | |
| 450 | M | B | 0.0000 | |
| 451 | H | B | 0.0000 | |
| 452 | P | B | -1.7421 | |
| 453 | D | B | -2.1605 | |
| 454 | G | B | -1.6238 | |
| 455 | S | B | 0.0000 | |
| 456 | A | B | 0.0000 | |
| 457 | V | B | 0.0000 | |
| 458 | V | B | 0.0000 | |
| 459 | V | B | 0.0000 | |
| 460 | V | B | 0.0000 | |
| 461 | L | B | 0.0000 | |
| 462 | N | B | 0.0000 | |
| 463 | R | B | -1.4809 | |
| 464 | S | B | -1.5020 | |
| 465 | S | B | -1.4985 | |
| 466 | K | B | -2.5591 | |
| 467 | D | B | -1.6772 | |
| 468 | V | B | -1.0546 | |
| 469 | P | B | -0.4792 | |
| 470 | L | B | 0.0000 | |
| 471 | T | B | 0.0000 | |
| 472 | I | B | 0.0000 | |
| 473 | K | B | -0.8244 | |
| 474 | D | B | 0.0000 | |
| 475 | P | B | -0.3726 | |
| 476 | A | B | -0.3003 | |
| 477 | V | B | -0.0067 | |
| 478 | G | B | -0.6485 | |
| 479 | F | B | -0.7679 | |
| 480 | L | B | 0.0000 | |
| 481 | E | B | -1.0405 | |
| 482 | T | B | -0.1340 | |
| 483 | I | B | 0.3376 | |
| 484 | S | B | 0.0000 | |
| 485 | P | B | -0.7712 | |
| 486 | G | B | -1.2254 | |
| 487 | Y | B | -0.7530 | |
| 488 | S | B | 0.0000 | |
| 489 | I | B | 0.0000 | |
| 490 | H | B | 0.0000 | |
| 491 | T | B | 0.0000 | |
| 492 | Y | B | 0.0000 | |
| 493 | L | B | 0.0000 | |
| 494 | W | B | 0.0000 | |
| 495 | R | B | -0.5868 | |
| 496 | R | B | -0.9927 | |
| 497 | Q | B | -1.1252 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine