Project name: 1Z0I Rab-21

Chain sequence(s)	A: AYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIET
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5342
• Maximal score value: 1.1013
• Average score: -1.0928
• Total score value: -172.6637

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
17	A	A	-1.1143
18	Y	A	-0.7387
19	S	A	-0.5410
20	F	A	-0.3264
21	K	A	-0.8606
22	V	A	0.0000
23	V	A	0.0000
24	L	A	0.0000
25	L	A	0.0000
26	G	A	0.0000
27	E	A	-0.7590
28	G	A	-0.3050
29	C	A	0.5753
30	V	A	0.0000
31	G	A	-0.2385
32	K	A	-0.2004
33	T	A	0.2130
34	S	A	-0.6585
35	L	A	0.0000
36	V	A	0.0000
37	L	A	-1.1024
38	R	A	-2.1437
39	Y	A	-1.3974
40	C	A	-1.5085
41	E	A	-2.6863
42	N	A	-2.8303
43	K	A	-2.7962
44	F	A	-1.9558
45	N	A	-1.8586
46	D	A	-2.7239
47	K	A	-2.6650
48	H	A	-1.4113
49	I	A	0.8806
50	T	A	0.1205
51	T	A	0.0764
52	L	A	-0.2535
53	Q	A	-0.9788
54	A	A	-0.2389
55	S	A	0.1288
56	F	A	0.7673
57	L	A	0.2886
58	T	A	-0.4145
59	K	A	-1.4193
60	K	A	-2.6575
61	L	A	0.0000
62	N	A	-2.9117
63	I	A	-1.7295
64	G	A	-1.7156
65	G	A	-2.1774
66	K	A	-3.1275
67	R	A	-3.5018
68	V	A	0.0000
69	N	A	-1.6120
70	L	A	0.0000
71	A	A	-0.1389
72	I	A	0.0000
73	W	A	0.5007
74	D	A	0.0276
75	T	A	-0.0173
76	A	A	-0.1136
86	P	A	0.0990
87	I	A	1.1013
88	Y	A	0.2421
89	Y	A	0.0000
90	R	A	-2.0437
91	D	A	-2.4888
92	S	A	0.0000
93	N	A	-1.3978
94	G	A	0.0000
95	A	A	0.0000
96	I	A	0.0000
97	L	A	0.0000
98	V	A	0.0000
99	Y	A	0.0000
100	D	A	0.0000
101	I	A	0.0000
102	T	A	-2.3310
103	D	A	-2.5106
104	E	A	-2.6347
105	D	A	-2.9638
106	S	A	0.0000
107	F	A	0.0000
108	Q	A	-2.1821
109	K	A	-2.2978
110	V	A	0.0000
111	K	A	-2.2214
112	N	A	-2.6565
113	W	A	-1.9784
114	V	A	0.0000
115	K	A	-3.2186
116	E	A	-2.6817
117	L	A	0.0000
118	R	A	-2.7040
119	K	A	-2.6852
120	M	A	-1.5111
121	L	A	-1.7981
122	G	A	-1.8044
123	N	A	-2.5271
124	E	A	-2.5250
125	I	A	-1.4982
126	C	A	-0.9605
127	L	A	0.0000
128	C	A	0.0000
129	I	A	0.0000
130	V	A	0.0000
131	G	A	0.0000
132	N	A	0.0000
133	K	A	-1.4276
134	I	A	-1.6256
135	D	A	-2.0923
136	L	A	-1.7738
137	E	A	-2.8960
138	K	A	-3.3068
139	E	A	-3.5342
140	R	A	-2.7758
141	H	A	-2.6012
142	V	A	0.0000
143	S	A	-1.0192
144	I	A	-0.6998
145	Q	A	-1.7304
146	E	A	-1.7837
147	A	A	0.0000
148	E	A	-2.2253
149	S	A	-1.9304
150	Y	A	-1.5513
151	A	A	0.0000
152	E	A	-2.5385
153	S	A	-1.3527
154	V	A	-0.9830
155	G	A	-1.4039
156	A	A	0.0000
157	K	A	-1.8913
158	H	A	-1.2229
159	Y	A	0.0000
160	H	A	-0.7199
161	T	A	0.0000
162	S	A	0.0000
163	A	A	0.0000
164	K	A	-2.6316
165	Q	A	-2.6049
166	N	A	-2.9787
167	K	A	-3.2641
168	G	A	-2.2943
169	I	A	0.0000
170	E	A	-3.0129
171	E	A	-2.9323
172	L	A	0.0000
173	F	A	0.0000
174	L	A	-1.1799
175	D	A	-1.4416
176	L	A	0.0000
177	C	A	0.0000
178	K	A	-1.4327
179	R	A	-1.2589
180	M	A	0.0000
181	I	A	-0.8673
182	E	A	-1.9506
183	T	A	-1.2994