Project name: 3mn5 A

Chain sequence(s)	A: TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRVGDERTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6153
• Maximal score value: 1.1819
• Average score: -0.7088
• Total score value: -245.9643

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
5	T	A	-0.4688
6	T	A	-0.3616
7	A	A	0.0000
8	L	A	0.0000
9	V	A	0.0000
10	C	A	0.0000
11	D	A	0.0000
12	N	A	0.0000
13	G	A	0.0000
14	S	A	0.0000
15	G	A	-0.1946
16	L	A	0.6695
17	V	A	0.0000
18	K	A	-0.0125
19	A	A	0.0000
20	G	A	0.0000
21	F	A	-0.7383
22	A	A	-0.4999
23	G	A	-1.2407
24	D	A	-2.7309
25	D	A	-2.6676
26	A	A	-1.8127
27	P	A	-1.3336
28	R	A	-2.1566
29	A	A	0.0000
30	V	A	0.1324
31	F	A	0.0000
32	P	A	-0.2071
33	S	A	0.0000
34	I	A	-0.4957
35	V	A	0.0000
36	G	A	-1.7909
37	R	A	-3.0270
38	V	A	-2.0762
39	G	A	0.0000
40	D	A	-2.8323
41	E	A	-3.1513
65	R	A	-2.2453
66	T	A	-0.6641
67	L	A	-0.1443
68	K	A	-0.8623
69	Y	A	-0.1906
70	P	A	0.0000
71	I	A	0.0000
72	E	A	-1.9730
73	H	A	-1.4562
74	G	A	-0.6643
75	I	A	-0.2398
76	I	A	-0.3582
77	T	A	-0.6553
78	N	A	-1.0877
79	W	A	-1.2937
80	D	A	-2.2804
81	D	A	0.0000
82	M	A	0.0000
83	E	A	-1.9173
84	K	A	-1.9924
85	I	A	0.0000
86	W	A	0.0000
87	H	A	-1.1398
88	H	A	0.0000
89	T	A	0.0000
90	F	A	0.0000
91	Y	A	-0.7856
92	N	A	-1.7140
93	E	A	-1.7962
94	L	A	0.0000
95	R	A	-1.9554
96	V	A	-1.2738
97	A	A	-1.3561
98	P	A	0.0000
99	E	A	-2.7912
100	E	A	-2.7514
101	H	A	-1.5451
102	P	A	-0.9199
103	T	A	0.0000
104	L	A	0.0000
105	L	A	0.0000
106	T	A	0.0000
107	E	A	0.0000
108	A	A	0.0000
109	P	A	0.0000
110	L	A	0.4796
111	N	A	-0.0598
112	P	A	-0.8348
113	K	A	-2.0680
114	A	A	-1.4154
115	N	A	-1.2970
116	R	A	-1.5265
117	E	A	-1.7266
118	K	A	-1.6823
119	M	A	0.0000
120	T	A	0.0000
121	Q	A	-1.6783
122	I	A	-1.2202
123	M	A	0.0000
124	F	A	0.0000
125	E	A	-2.5849
126	T	A	-1.6167
127	F	A	0.0000
128	N	A	-2.7439
129	V	A	0.0000
130	P	A	-1.6700
131	A	A	0.0000
132	M	A	0.0000
133	Y	A	0.0000
134	V	A	0.0000
135	A	A	0.0000
136	I	A	0.6605
137	Q	A	0.0252
138	A	A	0.0000
139	V	A	0.0000
140	L	A	0.0000
141	S	A	0.0000
142	L	A	0.0000
143	Y	A	0.1226
144	A	A	0.0039
145	S	A	-0.3054
146	G	A	-0.5175
147	R	A	-0.7942
148	T	A	-0.6097
149	T	A	-0.5430
150	G	A	0.0000
151	I	A	0.0000
152	V	A	0.0000
153	L	A	0.0000
154	D	A	-0.6459
155	S	A	0.0000
156	G	A	-0.7371
157	D	A	-0.9716
158	G	A	0.0000
159	V	A	0.0000
160	T	A	0.0000
161	H	A	0.0000
162	N	A	0.0000
163	V	A	0.0000
164	P	A	0.0000
165	I	A	0.0000
166	Y	A	0.3397
167	E	A	-1.0721
168	G	A	-0.0073
169	Y	A	1.1228
170	A	A	0.0000
171	L	A	0.3577
172	P	A	-0.1935
173	H	A	-1.1825
174	A	A	0.0000
175	I	A	0.0000
176	M	A	-0.8983
177	R	A	-1.4503
178	L	A	0.0000
179	D	A	-1.2545
180	L	A	0.0000
181	A	A	0.0000
182	G	A	0.0000
183	R	A	-1.1146
184	D	A	-0.6931
185	L	A	0.0000
186	T	A	0.0000
187	D	A	-0.9330
188	Y	A	-0.6204
189	L	A	0.0000
190	M	A	0.0000
191	K	A	-2.0380
192	I	A	0.0000
193	L	A	0.0000
194	T	A	-1.8004
195	E	A	-3.0224
196	R	A	-2.5776
197	G	A	-1.7830
198	Y	A	-0.9309
199	S	A	-0.5998
200	F	A	0.0000
201	V	A	1.1819
202	T	A	0.3516
203	T	A	-0.1141
204	A	A	-0.4536
205	E	A	-0.6694
206	R	A	-1.1381
207	E	A	-1.8949
208	I	A	-1.2750
209	V	A	0.0000
210	R	A	-2.3355
211	D	A	-2.5151
212	I	A	0.0000
213	K	A	0.0000
214	E	A	-2.5834
215	K	A	-2.7656
216	L	A	0.0000
217	C	A	0.0000
218	Y	A	-0.3758
219	V	A	0.0000
220	A	A	0.0000
221	L	A	-0.6165
222	D	A	-1.3381
223	F	A	-1.3435
224	E	A	-2.4266
225	N	A	-2.2361
226	E	A	-1.4282
227	M	A	-1.0309
228	A	A	-0.8215
229	T	A	-0.7272
230	A	A	-0.5215
231	A	A	-0.1309
232	S	A	-0.2844
233	S	A	-0.4759
234	S	A	-0.7574
235	S	A	-0.6883
236	L	A	-0.7891
237	E	A	-1.5052
238	K	A	-1.6895
239	S	A	-0.8845
240	Y	A	-1.0974
241	E	A	-1.8360
242	L	A	-1.4142
243	P	A	-1.6126
244	D	A	-2.4516
245	G	A	-1.9062
246	Q	A	-1.4330
247	V	A	-0.2962
248	I	A	0.0000
249	T	A	-0.6082
250	I	A	0.0000
251	G	A	-0.9002
252	N	A	-0.6408
253	E	A	0.0000
254	R	A	-0.9947
255	F	A	0.0000
256	R	A	-0.4331
257	C	A	0.0000
258	P	A	0.0000
259	E	A	0.0000
260	T	A	0.0000
261	L	A	0.0000
262	F	A	0.0000
263	Q	A	-0.5568
264	P	A	0.0000
265	S	A	-0.5715
266	F	A	0.1953
267	I	A	0.0165
268	G	A	-0.5258
269	M	A	-0.8387
270	E	A	-1.8369
271	S	A	-1.1773
272	A	A	-0.8709
273	G	A	0.0000
274	I	A	0.0000
275	H	A	-0.7020
276	E	A	-0.8898
277	T	A	-0.8023
278	T	A	0.0000
279	Y	A	-0.5257
280	N	A	-1.3766
281	S	A	0.0000
282	I	A	0.0000
283	M	A	-0.8918
284	K	A	-2.1291
285	C	A	0.0000
286	D	A	-1.7983
287	I	A	-0.4311
288	D	A	-2.0178
289	I	A	0.0000
290	R	A	-1.8832
291	K	A	-2.8183
292	D	A	-2.5189
293	L	A	0.0000
294	Y	A	0.0000
295	A	A	-1.8741
296	N	A	-1.3537
297	N	A	0.0000
298	V	A	0.0000
299	M	A	0.0000
300	S	A	0.0000
301	G	A	-1.1367
302	G	A	-1.2428
303	T	A	0.0000
304	T	A	0.0000
305	M	A	-0.6425
306	Y	A	0.0000
307	P	A	-0.4298
308	G	A	-0.6299
309	I	A	0.0000
310	A	A	-1.1605
311	D	A	-2.0961
312	R	A	0.0000
313	M	A	0.0000
314	Q	A	-1.6804
315	K	A	-1.5207
316	E	A	-0.9547
317	I	A	0.0000
318	T	A	-0.7790
319	A	A	-0.1512
320	L	A	0.2326
321	A	A	-0.0714
322	P	A	-0.5657
323	S	A	-0.4593
324	T	A	-0.5772
325	M	A	-1.3468
326	K	A	-2.4702
327	I	A	0.0000
328	K	A	-1.6177
329	I	A	0.0000
330	I	A	-0.1916
331	A	A	-0.6392
332	P	A	-0.7434
333	P	A	-1.1320
334	E	A	-1.8995
335	R	A	-1.5962
336	K	A	-2.1257
337	Y	A	-1.1388
338	S	A	0.0000
339	V	A	0.0000
340	W	A	0.0000
341	I	A	-0.5692
342	G	A	0.0000
343	G	A	0.0000
344	S	A	0.0000
345	I	A	0.4146
346	L	A	0.6070
347	A	A	0.0000
348	S	A	-0.0108
349	L	A	0.5147
350	S	A	-0.3506
351	T	A	-0.3714
352	F	A	0.0000
353	Q	A	-1.2526
354	Q	A	-1.4365
355	M	A	-0.4099
356	W	A	0.0000
357	I	A	0.0000
358	T	A	-1.2302
359	K	A	-2.5401
360	Q	A	-2.7960
361	E	A	-2.4022
362	Y	A	0.0000
363	D	A	-3.6153
364	E	A	-3.2183
365	A	A	-1.9898
366	G	A	-1.6196
367	P	A	-1.2268
368	S	A	-1.2686
369	I	A	0.0000
370	V	A	0.0000
371	H	A	-1.6046
372	R	A	-2.0620
373	K	A	-1.0552
374	C	A	-0.2609