Project name: 1yy8:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.812
• Maximal score value: 2.514
• Average score: -0.5163
• Total score value: -114.1045

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4745
2	V	B	-0.8717
3	Q	B	-1.6121
4	L	B	0.0000
5	K	B	-2.2205
6	Q	B	0.0000
7	S	B	-0.7906
8	G	B	-1.0821
9	P	B	-0.5082
10	G	B	-0.4073
11	L	B	0.0590
12	V	B	-0.5276
13	Q	B	-1.0740
14	P	B	-1.4082
15	S	B	-1.5008
16	Q	B	-1.9580
17	S	B	-1.7701
18	L	B	0.0000
19	S	B	-0.8802
20	I	B	0.0000
21	T	B	-0.5588
22	C	B	0.0000
23	T	B	-1.1552
24	V	B	0.0000
25	S	B	-1.2192
26	G	B	-0.9939
27	F	B	-0.5673
28	S	B	-0.9172
29	L	B	0.0000
30	T	B	-0.9474
31	N	B	-0.9019
32	Y	B	0.3961
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	-0.1161
39	Q	B	-0.4861
40	S	B	-1.0291
41	P	B	-1.1154
42	G	B	-1.5785
43	K	B	-2.0950
44	G	B	-0.9610
45	L	B	0.5592
46	E	B	-0.2917
47	W	B	0.1910
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.6407
53	S	B	-0.6756
54	G	B	-1.2470
55	G	B	-1.5063
56	N	B	-1.9505
57	T	B	-1.5357
58	D	B	-1.5680
59	Y	B	-0.6835
60	N	B	-0.7297
61	T	B	-0.5244
62	P	B	-0.4696
63	F	B	0.0000
64	T	B	-0.6128
65	S	B	-0.6868
66	R	B	-1.2436
67	L	B	0.0000
68	S	B	-1.2941
69	I	B	0.0000
70	N	B	-1.7858
71	K	B	-1.4302
72	D	B	-1.7744
73	N	B	-2.1984
74	S	B	-1.6774
75	K	B	-2.3618
76	S	B	-1.6003
77	Q	B	-1.5215
78	V	B	0.0000
79	F	B	-0.3776
80	F	B	0.0000
81	K	B	-2.0147
82	M	B	0.0000
83	N	B	-2.2669
84	S	B	-1.5942
85	L	B	0.0000
86	Q	B	-1.9348
87	S	B	-1.3598
88	N	B	-1.7111
89	D	B	0.0000
90	T	B	-0.5587
91	A	B	0.0000
92	I	B	0.3967
93	Y	B	0.0000
94	Y	B	0.0247
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.8444
100	T	B	1.4464
101	Y	B	1.9700
102	Y	B	1.8641
103	D	B	1.0331
104	Y	B	1.0576
105	E	B	0.1530
106	F	B	0.7482
107	A	B	0.8606
108	Y	B	0.6024
109	W	B	0.0947
110	G	B	-1.0476
111	Q	B	-1.5278
112	G	B	-0.7012
113	T	B	0.0000
114	L	B	0.0821
115	V	B	0.0000
116	T	B	-0.2203
117	V	B	0.0000
118	S	B	-0.4916
119	A	B	-0.2785
120	A	B	-0.2101
121	S	B	-0.4234
122	T	B	-0.6706
123	K	B	-1.1867
124	G	B	-1.4241
125	P	B	-0.4868
126	S	B	0.1208
127	V	B	0.8056
128	F	B	1.8663
129	P	B	0.5034
130	L	B	0.6007
131	A	B	-0.4906
132	P	B	0.0000
133	S	B	-1.5173
134	S	B	-1.3812
135	K	B	-1.9258
136	S	B	-1.1573
137	T	B	-1.0476
138	S	B	-0.9204
139	G	B	-0.8129
140	G	B	-0.8187
141	T	B	-0.6347
142	A	B	0.0000
143	A	B	0.0263
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.9644
148	V	B	0.0000
149	K	B	-0.1407
150	D	B	-0.5827
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.3828
155	P	B	-0.5329
156	V	B	-0.5944
157	T	B	-0.5699
158	V	B	-0.3878
159	S	B	-0.4703
160	W	B	0.0000
161	N	B	-0.7817
162	S	B	-0.6960
163	G	B	-0.5334
164	A	B	-0.2476
165	L	B	-0.0415
166	T	B	-0.3301
167	S	B	-0.3975
168	G	B	-0.5258
169	V	B	-0.0839
170	H	B	-0.5448
171	T	B	0.0552
172	F	B	0.7984
173	P	B	0.6493
174	A	B	1.2602
175	V	B	2.5140
176	L	B	2.2154
177	Q	B	0.7553
178	S	B	0.1256
179	S	B	-0.1795
180	G	B	0.2588
181	L	B	0.3710
182	Y	B	0.9304
183	S	B	0.7332
184	L	B	0.0000
185	S	B	0.6754
186	S	B	0.0000
187	V	B	0.3712
188	V	B	0.0000
189	T	B	-0.2709
190	V	B	0.0000
191	P	B	-0.5196
192	S	B	-0.5468
193	S	B	-0.5676
194	S	B	-0.6216
195	L	B	-0.8087
196	G	B	-0.9660
197	T	B	-0.7425
198	Q	B	-1.2473
199	T	B	-1.1539
200	Y	B	0.0000
201	I	B	-1.3615
202	C	B	0.0000
203	N	B	-1.4390
204	V	B	0.0000
205	N	B	-1.9361
206	H	B	0.0000
207	K	B	-2.8120
208	P	B	-1.5767
209	S	B	-1.8068
210	N	B	-2.6208
211	T	B	-2.0408
212	K	B	-2.6348
213	V	B	-1.4441
214	D	B	-2.4692
215	K	B	-1.8500
216	R	B	-2.2282
217	V	B	0.0000
218	E	B	-2.7474
219	P	B	-1.8622
220	K	B	-2.2981
221	S	B	-1.5620