Project name: 4gw5:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9256
• Maximal score value: 2.4187
• Average score: -0.5026
• Total score value: -108.5645

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.5065
2	V	B	-0.9264
3	Q	B	-1.7328
4	L	B	0.0000
5	K	B	-2.2382
6	Q	B	0.0000
7	S	B	-0.7543
8	G	B	-0.9693
9	P	B	-0.4289
10	G	B	-0.5086
11	L	B	-0.1684
12	V	B	0.0000
13	Q	B	-1.7871
14	P	B	-1.6994
15	S	B	-1.5217
16	Q	B	-1.7775
17	S	B	-1.4482
18	L	B	0.0000
19	S	B	-0.5444
20	I	B	0.0000
21	T	B	-0.4825
22	C	B	0.0000
23	T	B	-1.1791
24	V	B	0.0000
25	S	B	-1.2683
26	G	B	-1.0200
27	F	B	-0.5612
28	S	B	-0.8557
29	L	B	0.0000
30	T	B	-0.8982
31	N	B	-0.8550
32	Y	B	0.4578
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.3524
40	S	B	-0.9599
41	P	B	-1.0999
42	G	B	-1.6402
43	K	B	-2.0586
44	G	B	-0.6577
45	L	B	0.7444
46	E	B	0.0508
47	W	B	0.3744
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.6135
53	S	B	-0.6144
54	G	B	-1.2232
55	G	B	-1.5112
56	N	B	-1.9752
57	T	B	-1.5730
58	D	B	-1.6535
59	Y	B	-0.7323
60	N	B	-0.6731
61	T	B	-0.5273
62	P	B	-0.4542
63	F	B	0.0000
64	T	B	-0.6106
65	S	B	-0.5511
66	R	B	-0.8504
67	L	B	0.0000
68	S	B	-0.9751
69	I	B	0.0000
70	N	B	-1.6908
71	K	B	-1.4165
72	D	B	-1.7539
73	N	B	-2.1601
74	S	B	-1.6556
75	K	B	-2.3533
76	S	B	-1.5950
77	Q	B	-1.5138
78	V	B	0.0000
79	F	B	-0.2402
80	F	B	0.0000
81	K	B	-1.2036
82	M	B	0.0000
83	N	B	-1.4048
84	S	B	-1.3718
85	L	B	0.0000
86	Q	B	-2.2066
87	S	B	-1.6230
88	N	B	-2.1135
89	D	B	0.0000
90	T	B	-0.6988
91	A	B	0.0000
92	I	B	0.5263
93	Y	B	0.0000
94	Y	B	0.0470
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.6831
100	T	B	1.3382
101	Y	B	1.9135
102	Y	B	1.7609
103	D	B	0.7811
104	Y	B	0.7121
105	E	B	-0.1551
106	F	B	0.5374
107	A	B	0.7343
108	Y	B	0.4823
109	W	B	0.0157
110	G	B	-1.0875
111	Q	B	-1.5165
112	G	B	-0.6503
113	T	B	0.0000
114	L	B	0.2938
115	V	B	0.0000
116	T	B	-0.3762
117	V	B	0.0000
118	S	B	-0.6698
119	A	B	-0.5445
120	A	B	-0.3504
121	S	B	-0.5335
122	T	B	-0.7176
123	K	B	-1.1758
124	G	B	-1.3946
125	P	B	0.0000
126	S	B	-0.0199
127	V	B	0.0000
128	F	B	0.9713
129	P	B	-0.0927
130	L	B	0.3343
131	A	B	-0.9408
132	P	B	0.0000
133	S	B	-0.7942
138	S	B	-0.6634
139	G	B	-0.8602
140	G	B	-0.9418
141	T	B	-0.6635
142	A	B	-0.4037
143	A	B	0.0644
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.7540
148	V	B	0.0000
149	K	B	-0.1106
150	D	B	-0.5408
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.0896
155	P	B	-0.5153
156	V	B	-0.6547
157	T	B	-0.6078
158	V	B	-0.3785
159	S	B	-0.4072
160	W	B	0.0000
161	N	B	-0.8661
162	S	B	-0.5997
163	G	B	-0.5234
164	A	B	-0.2571
165	L	B	-0.0660
166	T	B	-0.3202
167	S	B	-0.3879
168	G	B	-0.4938
169	V	B	-0.0293
170	H	B	-0.4681
171	T	B	0.1340
172	F	B	0.9527
173	P	B	0.7060
174	A	B	1.2778
175	V	B	2.4187
176	L	B	2.0044
177	Q	B	0.6294
178	S	B	0.0487
179	S	B	-0.2369
180	G	B	0.1822
181	L	B	0.2928
182	Y	B	0.8434
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6854
186	S	B	0.0000
187	V	B	0.4210
188	V	B	0.0000
189	T	B	-0.2104
190	V	B	0.0000
191	P	B	-0.5852
192	S	B	-0.6404
193	S	B	-0.6538
194	S	B	-0.7125
195	L	B	-0.8939
196	G	B	-1.0286
197	T	B	-0.8050
198	Q	B	-1.3876
199	T	B	-1.2718
200	Y	B	0.0000
201	I	B	-1.4098
202	C	B	0.0000
203	N	B	0.0000
204	V	B	0.0000
205	N	B	-2.0721
206	H	B	0.0000
207	K	B	-2.7474
208	P	B	-1.5767
209	S	B	-1.8268
210	N	B	-2.6124
211	T	B	-2.0961
212	K	B	-2.6090
213	V	B	-1.3610
214	D	B	-2.1141
215	K	B	-1.9060
216	R	B	-2.5454
217	V	B	0.0000
218	E	B	-2.9256
219	P	B	-1.9267
220	K	B	-2.2750