Project name: ea43ca57a3959f0

Chain sequence(s)	H: QVQLQESGPGLVQPSETLSLTCTVSGGSVSSGDTYITWIRQSPGQGLEWIGHIYYSGNTNYNPSLRSRLTISIDTSRTQFSLQLSSVTAADTAVYYCSRDRVTGAFDIWGQGTMVTVSS; L: DIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQRPGRAPRLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYFCQHFDHLPLAFGGGTRVEIR
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.0261
• Maximal score value: 1.3509
• Average score: -0.2643
• Total score value: -59.732

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.1616
2	V	H	-0.2937
3	Q	H	-1.1613
4	L	H	0.0000
5	Q	H	-1.1983
6	E	H	0.0000
7	S	H	-0.1996
8	G	H	-0.5225
9	P	H	-0.3335
11	G	H	-0.1203
12	L	H	1.1468
13	V	H	0.0000
14	Q	H	-0.7523
15	P	H	-0.2924
16	S	H	-0.5993
17	E	H	-1.8601
18	T	H	-0.3854
19	L	H	0.0000
20	S	H	-0.2746
21	L	H	0.0000
22	T	H	-0.0243
23	C	H	0.0000
24	T	H	-0.0554
25	V	H	0.0000
26	S	H	-0.2997
27	G	H	-0.5339
28	G	H	-0.3983
29	S	H	-0.2330
30	V	H	0.0000
31	S	H	-0.2001
34	S	H	-0.1280
35	G	H	-0.5407
36	D	H	-1.8280
37	T	H	-0.4739
38	Y	H	0.3467
39	I	H	0.0000
40	T	H	0.0000
41	W	H	0.0000
42	I	H	0.0000
43	R	H	0.0000
44	Q	H	-0.1830
45	S	H	-0.1120
46	P	H	-0.3477
47	G	H	-0.7335
48	Q	H	-1.3234
49	G	H	-0.4354
50	L	H	0.0000
51	E	H	-0.1829
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	H	H	0.0000
56	I	H	0.0000
57	Y	H	0.4611
58	Y	H	1.0002
59	S	H	-0.1139
63	G	H	-0.7185
64	N	H	-1.3594
65	T	H	-0.3550
66	N	H	-0.4863
67	Y	H	0.1229
68	N	H	0.0000
69	P	H	-0.3271
70	S	H	-0.2387
71	L	H	0.0000
72	R	H	-1.3558
74	S	H	-0.5315
75	R	H	-0.4743
76	L	H	0.0000
77	T	H	-0.1052
78	I	H	0.0000
79	S	H	-0.0919
80	I	H	0.2539
81	D	H	-0.7642
82	T	H	-0.2422
83	S	H	-0.5594
84	R	H	-1.8851
85	T	H	-0.3954
86	Q	H	-0.2485
87	F	H	0.0000
88	S	H	-0.0733
89	L	H	0.0000
90	Q	H	-0.7292
91	L	H	0.0000
92	S	H	-0.1110
93	S	H	-0.4419
94	V	H	0.0000
95	T	H	-0.0459
96	A	H	0.0587
97	A	H	0.0692
98	D	H	0.0000
99	T	H	-0.0166
100	A	H	0.0000
101	V	H	0.4917
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	S	H	0.0000
106	R	H	0.0000
107	D	H	0.0000
108	R	H	-1.1905
109	V	H	0.6069
110	T	H	0.0882
113	G	H	0.0000
114	A	H	0.0000
115	F	H	0.0000
116	D	H	-0.3707
117	I	H	0.2669
118	W	H	0.1761
119	G	H	0.0000
120	Q	H	-1.2079
121	G	H	-0.2743
122	T	H	0.1317
123	M	H	0.8698
124	V	H	0.0000
125	T	H	0.1061
126	V	H	0.0000
127	S	H	-0.1329
128	S	H	-0.3020
1	D	L	-1.7894
2	I	L	0.0000
3	Q	L	-1.1983
4	M	L	0.0000
5	T	L	-0.0709
6	Q	L	0.0000
7	S	L	-0.1298
8	P	L	-0.1881
9	S	L	-0.2744
10	S	L	-0.4165
11	L	L	0.2188
12	S	L	-0.2653
13	A	L	-0.0322
14	S	L	-0.0386
15	V	L	1.3509
16	G	L	-0.2904
17	D	L	-1.3233
18	R	L	-2.0199
19	V	L	0.0000
20	T	L	-0.0727
21	I	L	0.0000
22	T	L	-0.0377
23	C	L	0.0000
24	Q	L	-0.9884
25	A	L	0.0000
26	S	L	-0.3177
27	Q	L	-1.5488
28	D	L	-2.0261
29	I	L	0.0000
36	S	L	-0.1982
37	N	L	-0.2930
38	Y	L	0.5307
39	L	L	0.0000
40	N	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	-0.2696
45	R	L	-0.7933
46	P	L	-0.4721
47	G	L	-0.8511
48	R	L	-1.9277
49	A	L	-0.3350
50	P	L	0.0000
51	R	L	-1.1598
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	0.2058
56	D	L	-0.5754
57	A	L	0.0000
65	S	L	-0.4103
66	N	L	-0.8905
67	L	L	0.3791
68	E	L	-0.2319
69	T	L	-0.2189
70	G	L	-0.4457
71	V	L	0.0796
72	P	L	-0.1160
74	S	L	-0.2865
75	R	L	-0.3371
76	F	L	0.0000
77	S	L	-0.1658
78	G	L	0.0000
79	S	L	-0.2694
80	G	L	-0.2663
83	S	L	-0.3014
84	G	L	-0.3950
85	T	L	-0.5436
86	D	L	-1.8824
87	F	L	0.0000
88	T	L	-0.0258
89	F	L	0.0000
90	T	L	-0.0232
91	I	L	0.0000
92	S	L	-0.3135
93	S	L	-0.1482
94	L	L	0.0000
95	Q	L	-0.3935
96	P	L	-0.6037
97	E	L	-1.8576
98	D	L	0.0000
99	I	L	0.8129
100	A	L	0.0000
101	T	L	-0.2372
102	Y	L	0.0000
103	F	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	H	L	0.0000
107	F	L	0.2046
108	D	L	-0.6688
109	H	L	-0.7926
114	L	L	0.4187
115	P	L	0.0000
116	L	L	0.0000
117	A	L	0.0133
118	F	L	0.0000
119	G	L	0.0000
120	G	L	-0.4754
121	G	L	-0.1356
122	T	L	0.0000
123	R	L	-1.5678
124	V	L	0.0000
125	E	L	-1.7701
126	I	L	-0.3363
127	R	L	-1.7928