Project name: 5th2:B

Chain sequence(s)	B: QVQLKQSGPGLVQQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSGGTAALGCCLVKDYFPEPVVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9879
• Maximal score value: 2.4597
• Average score: -0.5079
• Total score value: -109.6982

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.3667
2	V	B	-0.6407
3	Q	B	-1.2823
4	L	B	0.0000
5	K	B	-2.1405
6	Q	B	-1.2785
7	S	B	-0.8610
8	G	B	-1.0823
9	P	B	-0.5244
10	G	B	-0.4218
11	L	B	0.0249
12	V	B	-0.6202
13	Q	B	-1.1727
14	P	B	-1.4180
15	S	B	-1.4571
16	Q	B	-1.8522
17	S	B	-1.5452
18	L	B	0.0000
19	S	B	-0.6480
20	I	B	0.0000
21	T	B	-0.5452
22	C	B	0.0000
23	T	B	-1.1220
24	V	B	0.0000
25	S	B	-1.1180
26	G	B	-0.8873
27	F	B	-0.4946
28	S	B	-0.8952
29	L	B	0.0000
30	T	B	-0.9366
31	N	B	-0.8843
32	Y	B	0.4361
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.4332
40	S	B	-1.0070
41	P	B	-1.1390
42	G	B	-1.6677
43	K	B	-2.0578
44	G	B	-0.7263
45	L	B	0.6692
46	E	B	0.0360
47	W	B	0.3856
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.6057
53	S	B	-0.6570
54	G	B	-1.2407
55	G	B	-1.5461
56	N	B	-1.9513
57	T	B	-1.5188
58	D	B	-1.5163
59	Y	B	-0.6867
60	N	B	-0.6627
61	T	B	-0.5291
62	P	B	-0.4664
63	F	B	0.0000
64	T	B	-0.6062
65	S	B	-0.5801
66	R	B	-0.9479
67	L	B	0.0000
68	S	B	-1.1008
69	I	B	0.0000
70	N	B	-1.7552
71	K	B	-1.4743
72	D	B	-1.8386
73	N	B	-2.2762
74	S	B	-1.7117
75	K	B	-2.3874
76	S	B	-1.6163
77	Q	B	-1.5528
78	V	B	0.0000
79	F	B	-0.3113
80	F	B	0.0000
81	K	B	-1.5377
82	M	B	0.0000
83	N	B	-1.6176
84	S	B	-1.3877
85	L	B	0.0000
86	Q	B	-1.9553
87	S	B	-1.4297
88	N	B	-2.0438
89	D	B	0.0000
90	T	B	-0.6914
91	A	B	0.0000
92	I	B	0.3663
93	Y	B	0.0000
94	Y	B	-0.1566
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.8363
100	T	B	1.4554
101	Y	B	1.9803
102	Y	B	1.8636
103	D	B	0.9817
104	Y	B	1.0146
105	E	B	0.2565
106	F	B	0.7491
107	A	B	0.8468
108	Y	B	0.6557
109	W	B	0.1111
110	G	B	0.0000
111	Q	B	-1.5036
112	G	B	-0.7267
113	T	B	0.0000
114	L	B	0.0943
115	V	B	0.0000
116	T	B	-0.2839
117	V	B	0.0000
118	S	B	-0.5338
119	A	B	-0.2165
120	A	B	-0.2349
121	S	B	-0.4403
122	T	B	-0.5902
123	K	B	-1.1639
124	G	B	-1.5235
125	P	B	0.0000
126	S	B	-0.0500
127	V	B	0.0000
128	F	B	1.0290
129	P	B	0.0327
130	L	B	0.4425
131	A	B	-0.8100
132	P	B	0.0000
133	S	B	-0.7387
139	G	B	-0.7685
140	G	B	-0.8710
141	T	B	-0.6342
142	A	B	-0.3767
143	A	B	0.1084
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.7745
148	V	B	0.0000
149	K	B	-0.1824
150	D	B	-0.5726
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.2667
155	P	B	-0.7212
156	V	B	-0.8427
157	T	B	-0.7890
158	V	B	-0.3302
159	S	B	-0.5372
160	W	B	0.0000
161	N	B	-0.7902
162	S	B	-0.6622
163	G	B	-0.5278
164	A	B	-0.2376
165	L	B	-0.0251
166	T	B	-0.3023
167	S	B	-0.3750
168	G	B	-0.4736
169	V	B	0.0107
170	H	B	-0.4227
171	T	B	0.2074
172	F	B	0.9604
173	P	B	0.7195
174	A	B	1.2696
175	V	B	2.4597
176	L	B	2.1188
177	Q	B	0.7337
178	S	B	0.1059
179	S	B	-0.2125
180	G	B	0.2039
181	L	B	0.3106
182	Y	B	0.8312
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6843
186	S	B	0.0000
187	V	B	0.4853
188	V	B	0.0000
189	T	B	-0.2128
190	V	B	0.0000
191	P	B	-0.5576
192	S	B	-0.6186
193	S	B	-0.6089
194	S	B	-0.5861
195	L	B	-0.8906
196	G	B	-0.9906
197	T	B	-0.6996
198	Q	B	-1.1714
199	T	B	-1.1746
200	Y	B	0.0000
201	I	B	-1.4603
202	C	B	0.0000
203	N	B	-1.6101
204	V	B	0.0000
205	N	B	-2.5577
206	H	B	0.0000
207	K	B	-2.9879
208	P	B	-1.6956
209	S	B	-1.8763
210	N	B	-2.7349
211	T	B	-2.2195
212	K	B	-2.9058
213	V	B	-1.6413
214	D	B	-2.4972
215	K	B	-2.0469
216	R	B	-2.5738
217	V	B	0.0000
218	E	B	-2.8440
219	P	B	-1.8714
220	K	B	-2.2978
221	S	B	-1.2959