Project name: eb4c21d116b2587

Chain sequence(s)	A: AQVLTQTASSVSAAVGGTVTISCQSSQSVYNKNWLGWYQQKPGQPPRLLIYGASTLASGVPSRFSGSGSGTQFTLTISDVQCDDAATYYCAGGYSNNIVSFGGGTRVVVEVATLAPTVLIFPPSPAELATGTATIVCVANKYFPDGTVTWQVDGKPLTTGIETSKTPQNSDDCTYNLSSTLTLKSDEYNSHDEYTCQVAQGSGSPVVQSFNRGDCDYKDDDDKDYKDDDDKDYKDDDDK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -5.4446
• Maximal score value: 1.6368
• Average score: -0.8234
• Total score value: -196.7839

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	0.1464
2	Q	A	0.0000
3	V	A	1.5456
4	L	A	0.0000
5	T	A	-0.2426
6	Q	A	0.0000
7	T	A	-0.3859
8	A	A	-0.0850
9	S	A	-0.3148
10	S	A	-0.0471
11	V	A	0.4489
12	S	A	0.2961
13	A	A	0.2196
14	A	A	0.1883
15	V	A	-0.2093
16	G	A	-0.8583
17	G	A	-0.7710
18	T	A	-0.8182
19	V	A	0.0000
20	T	A	-0.0982
21	I	A	0.0000
22	S	A	-0.5542
23	C	A	0.0000
24	Q	A	-1.3691
25	S	A	0.0000
26	S	A	-0.5559
27	Q	A	-0.7887
28	S	A	-0.2980
29	V	A	0.3173
30	Y	A	0.4055
31	N	A	-1.1751
32	K	A	-1.7771
33	N	A	0.0000
34	W	A	0.5048
35	L	A	0.0000
36	G	A	0.6534
37	W	A	0.0000
38	Y	A	0.2546
39	Q	A	0.0000
40	Q	A	-0.9655
41	K	A	-1.3487
42	P	A	-0.9885
43	G	A	-1.0603
44	Q	A	-1.3007
45	P	A	-1.1109
46	P	A	-1.0000
47	R	A	-1.0213
48	L	A	0.2679
49	L	A	0.0000
50	I	A	0.0000
51	Y	A	1.0069
52	G	A	0.2753
53	A	A	0.0000
54	S	A	0.0713
55	T	A	0.2155
56	L	A	0.5017
57	A	A	0.1970
58	S	A	-0.2082
59	G	A	-0.3686
60	V	A	-0.1384
61	P	A	-0.2901
62	S	A	-0.5767
63	R	A	-0.9833
64	F	A	0.0000
65	S	A	-0.2892
66	G	A	-0.1940
67	S	A	-0.4830
68	G	A	-0.9283
69	S	A	-1.2073
70	G	A	-1.2140
71	T	A	-1.4077
72	Q	A	-1.6002
73	F	A	0.0000
74	T	A	-0.6302
75	L	A	0.0000
76	T	A	-0.4463
77	I	A	0.0000
78	S	A	-1.2250
79	D	A	-1.8734
80	V	A	0.0000
81	Q	A	-1.4825
82	C	A	-1.5956
83	D	A	-2.4478
84	D	A	0.0000
85	A	A	-0.9533
86	A	A	0.0000
87	T	A	-0.2110
88	Y	A	0.0000
89	Y	A	0.0450
90	C	A	0.0000
91	A	A	0.9107
92	G	A	0.0000
93	G	A	0.4717
94	Y	A	0.7828
95	S	A	-0.1188
96	N	A	-1.1792
97	N	A	-0.7836
98	I	A	1.3825
99	V	A	1.1323
100	S	A	0.5219
101	F	A	0.0000
102	G	A	-0.3262
103	G	A	-0.3238
104	G	A	0.0000
105	T	A	-0.0363
106	R	A	0.0000
107	V	A	0.4406
108	V	A	0.0000
109	V	A	0.8699
110	E	A	0.2530
111	V	A	1.6368
112	A	A	1.1157
113	T	A	0.7060
114	L	A	0.8435
115	A	A	0.0000
116	P	A	0.1091
117	T	A	0.8468
118	V	A	1.6286
119	L	A	1.6162
120	I	A	1.5560
121	F	A	0.6954
122	P	A	0.1665
123	P	A	-0.5726
124	S	A	-0.8200
125	P	A	-0.6380
126	A	A	-0.1269
127	E	A	-0.7775
128	L	A	1.0109
129	A	A	0.2085
130	T	A	-0.8175
131	G	A	-1.2088
132	T	A	0.0000
133	A	A	-0.0217
134	T	A	0.0000
135	I	A	0.9459
136	V	A	0.0000
137	C	A	0.7549
138	V	A	0.0000
139	A	A	-0.2860
140	N	A	-0.7444
141	K	A	0.0000
142	Y	A	0.3719
143	F	A	0.5379
144	P	A	-0.9537
145	D	A	-1.8972
146	G	A	-0.9980
147	T	A	-0.5870
148	V	A	0.1436
149	T	A	0.1586
150	W	A	0.0000
151	Q	A	-1.6509
152	V	A	0.0000
153	D	A	-3.1737
154	G	A	-2.4875
155	K	A	-2.6400
156	P	A	-1.3663
157	L	A	-0.4853
158	T	A	-0.3129
159	T	A	-0.2027
160	G	A	-0.3789
161	I	A	-0.3585
162	E	A	-1.6755
163	T	A	-1.1943
164	S	A	-1.5594
165	K	A	-2.1476
166	T	A	-1.2014
167	P	A	-1.0055
168	Q	A	-1.0796
169	N	A	-1.8223
170	S	A	-2.2369
171	D	A	-2.9815
172	D	A	-2.6052
173	C	A	0.0000
174	T	A	-0.8679
175	Y	A	0.0000
176	N	A	-1.1061
177	L	A	-0.9062
178	S	A	-0.4896
179	S	A	0.0000
180	T	A	-0.2683
181	L	A	0.0000
182	T	A	-0.6634
183	L	A	-1.4360
184	K	A	-2.8723
185	S	A	0.0000
186	D	A	-3.4420
187	E	A	-3.1864
188	Y	A	0.0000
189	N	A	-2.6571
190	S	A	-2.2353
191	H	A	-2.6186
192	D	A	-2.9563
193	E	A	-2.9246
194	Y	A	0.0000
195	T	A	-0.6832
196	C	A	0.0000
197	Q	A	0.1782
198	V	A	0.0000
199	A	A	-0.3523
200	Q	A	-0.6335
201	G	A	-0.7002
202	S	A	-0.2995
203	G	A	-0.6307
204	S	A	-0.1856
205	P	A	0.0455
206	V	A	0.7653
207	V	A	1.4734
208	Q	A	0.8259
209	S	A	0.2327
210	F	A	-0.6417
211	N	A	-2.3871
212	R	A	-2.6127
213	G	A	-2.5645
214	D	A	-3.0047
215	C	A	-2.0276
216	D	A	-2.6211
217	Y	A	-2.4173
218	K	A	-3.9719
219	D	A	-4.9946
220	D	A	-4.9524
221	D	A	-5.0970
222	D	A	-5.1944
223	K	A	-5.4446
224	D	A	-3.4940
225	Y	A	-2.3694
226	K	A	-3.9062
227	D	A	-4.0977
228	D	A	-5.0025
229	D	A	-4.8073
230	D	A	-4.8600
231	K	A	-4.2464
232	D	A	-3.5950
233	Y	A	-1.8455
234	K	A	-4.2266
235	D	A	-4.6217
236	D	A	-4.7050
237	D	A	-4.6402
238	D	A	-4.2051
239	K	A	-3.3333