Project name: 4zyp:L
Status: done
submitted: 2019-03-20 20:23:44, status changed: 2019-03-20 20:35:41
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSTLSASVGDRVTITCSASSRVGYMHWYQQKPGKAPKLLIYDTSKLASGVPSRFSGSGSGTEFTLTISSLQPDDFATYYCFQGSGYPFTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7918
-
Maximal score value
-
2.0122
-
Average score
-
-0.7556
-
Total score value
-
-159.4362
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.5462 |
|
| 2 |
I |
L |
-0.9452 |
|
| 3 |
Q |
L |
-1.1771 |
|
| 4 |
M |
L |
-0.1886 |
|
| 5 |
T |
L |
-0.3077 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.5783 |
|
| 8 |
P |
L |
-0.5713 |
|
| 9 |
S |
L |
-0.7337 |
|
| 10 |
T |
L |
-0.5892 |
|
| 11 |
L |
L |
-0.2928 |
|
| 12 |
S |
L |
0.0000 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-0.6979 |
|
| 15 |
V |
L |
0.6448 |
|
| 16 |
G |
L |
-0.9620 |
|
| 17 |
D |
L |
-2.4938 |
|
| 18 |
R |
L |
-2.7132 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.7203 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.5410 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
S |
L |
-1.1044 |
|
| 25 |
A |
L |
-1.1268 |
|
| 26 |
S |
L |
-1.3209 |
|
| 27 |
S |
L |
-1.6391 |
|
| 29 |
R |
L |
-2.1077 |
|
| 30 |
V |
L |
-0.9919 |
|
| 31 |
G |
L |
-0.4877 |
|
| 32 |
Y |
L |
0.3525 |
|
| 33 |
M |
L |
0.0000 |
|
| 34 |
H |
L |
0.2113 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.3623 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.1989 |
|
| 39 |
K |
L |
-1.4722 |
|
| 40 |
P |
L |
-1.1552 |
|
| 41 |
G |
L |
-1.5644 |
|
| 42 |
K |
L |
-2.3720 |
|
| 43 |
A |
L |
-1.4634 |
|
| 44 |
P |
L |
-1.2796 |
|
| 45 |
K |
L |
-1.2163 |
|
| 46 |
L |
L |
0.2522 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.3224 |
|
| 50 |
D |
L |
-1.1287 |
|
| 51 |
T |
L |
-0.7339 |
|
| 52 |
S |
L |
-1.1492 |
|
| 53 |
K |
L |
-1.7985 |
|
| 54 |
L |
L |
-0.4075 |
|
| 55 |
A |
L |
-0.3003 |
|
| 56 |
S |
L |
-0.3095 |
|
| 57 |
G |
L |
-0.3385 |
|
| 58 |
V |
L |
-0.1322 |
|
| 59 |
P |
L |
-0.3146 |
|
| 60 |
S |
L |
-0.4208 |
|
| 61 |
R |
L |
-0.6531 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.6178 |
|
| 64 |
G |
L |
-0.8162 |
|
| 65 |
S |
L |
-0.9762 |
|
| 66 |
G |
L |
-0.9770 |
|
| 67 |
S |
L |
-1.0599 |
|
| 68 |
G |
L |
-1.3139 |
|
| 69 |
T |
L |
-1.5540 |
|
| 70 |
E |
L |
-2.0324 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.6574 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6500 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.5634 |
|
| 77 |
S |
L |
-1.3634 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.7402 |
|
| 80 |
P |
L |
-0.5222 |
|
| 81 |
D |
L |
-1.7324 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
0.1366 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
-0.4487 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.5798 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
F |
L |
1.3552 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
G |
L |
0.6111 |
|
| 92 |
S |
L |
0.0771 |
|
| 93 |
G |
L |
0.2220 |
|
| 94 |
Y |
L |
1.0265 |
|
| 95 |
P |
L |
0.3900 |
|
| 96 |
F |
L |
1.4727 |
|
| 97 |
T |
L |
1.1088 |
|
| 98 |
F |
L |
2.0122 |
|
| 99 |
G |
L |
0.5788 |
|
| 100 |
G |
L |
-0.3695 |
|
| 101 |
G |
L |
-0.2107 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.0485 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
0.0000 |
|
| 106 |
I |
L |
0.0135 |
|
| 107 |
K |
L |
-1.5327 |
|
| 108 |
R |
L |
-1.8754 |
|
| 109 |
T |
L |
-0.3613 |
|
| 110 |
V |
L |
0.8501 |
|
| 111 |
A |
L |
0.1623 |
|
| 112 |
A |
L |
-0.0811 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.2030 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.1352 |
|
| 117 |
I |
L |
1.2202 |
|
| 118 |
F |
L |
1.4967 |
|
| 119 |
P |
L |
-0.0041 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.7206 |
|
| 122 |
D |
L |
-3.2282 |
|
| 123 |
E |
L |
-3.4333 |
|
| 124 |
Q |
L |
-2.5746 |
|
| 125 |
L |
L |
-2.5475 |
|
| 126 |
K |
L |
-3.0556 |
|
| 127 |
S |
L |
-1.9655 |
|
| 128 |
G |
L |
-1.4152 |
|
| 129 |
T |
L |
-1.2551 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0477 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.6958 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.8066 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6993 |
|
| 138 |
N |
L |
-1.3960 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.2431 |
|
| 142 |
R |
L |
-1.7656 |
|
| 143 |
E |
L |
-2.8217 |
|
| 144 |
A |
L |
-2.1373 |
|
| 145 |
K |
L |
-2.3226 |
|
| 146 |
V |
L |
-1.0693 |
|
| 147 |
Q |
L |
-0.5576 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.6138 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-2.0434 |
|
| 152 |
N |
L |
-1.5614 |
|
| 153 |
A |
L |
-0.3013 |
|
| 154 |
L |
L |
0.7447 |
|
| 155 |
Q |
L |
-0.1407 |
|
| 156 |
S |
L |
-0.3929 |
|
| 157 |
G |
L |
-0.9775 |
|
| 158 |
N |
L |
-0.8807 |
|
| 159 |
S |
L |
-1.3862 |
|
| 160 |
Q |
L |
-2.2803 |
|
| 161 |
E |
L |
-2.1605 |
|
| 162 |
S |
L |
-0.7710 |
|
| 163 |
V |
L |
0.2102 |
|
| 164 |
T |
L |
-0.9122 |
|
| 165 |
E |
L |
-2.1250 |
|
| 166 |
Q |
L |
-2.4706 |
|
| 167 |
D |
L |
-3.2087 |
|
| 168 |
S |
L |
-2.4030 |
|
| 169 |
K |
L |
-3.0139 |
|
| 170 |
D |
L |
-2.9649 |
|
| 171 |
S |
L |
-2.0175 |
|
| 172 |
T |
L |
-1.8135 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.7573 |
|
| 175 |
L |
L |
-0.2069 |
|
| 176 |
S |
L |
-0.1746 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6929 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.5129 |
|
| 181 |
L |
L |
-0.6749 |
|
| 182 |
S |
L |
-1.2783 |
|
| 183 |
K |
L |
-2.2264 |
|
| 184 |
A |
L |
-1.9462 |
|
| 185 |
D |
L |
-2.6283 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.6584 |
|
| 188 |
K |
L |
-3.7918 |
|
| 189 |
H |
L |
-3.3381 |
|
| 190 |
K |
L |
-3.4498 |
|
| 191 |
V |
L |
-1.9214 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
-0.7580 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.8355 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2111 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.6413 |
|
| 200 |
G |
L |
-0.3430 |
|
| 201 |
L |
L |
-0.3566 |
|
| 202 |
S |
L |
-0.4466 |
|
| 203 |
S |
L |
-0.4129 |
|
| 204 |
P |
L |
-0.5092 |
|
| 205 |
V |
L |
-0.0207 |
|
| 206 |
T |
L |
-0.4307 |
|
| 207 |
K |
L |
-0.4355 |
|
| 208 |
S |
L |
-0.5205 |
|
| 209 |
F |
L |
-0.8484 |
|
| 210 |
N |
L |
-2.1965 |
|
| 211 |
R |
L |
-2.5487 |
|
| 212 |
G |
L |
-1.5132 |
|