| Chain sequence(s) |
A: GPLGSEDDLYRQSLEIISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVTNWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFFHVQDLEGG B: EEEWAREIGAQLRRIADDLNAQYERRM |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 147 | G | A | -0.7166 | |
| 148 | P | A | -0.3185 | |
| 149 | L | A | 0.1723 | |
| 150 | G | A | -0.6167 | |
| 151 | S | A | -1.3057 | |
| 152 | E | A | -2.3809 | |
| 153 | D | A | -2.3130 | |
| 154 | D | A | -2.4938 | |
| 155 | L | A | -1.7805 | |
| 156 | Y | A | -1.8648 | |
| 157 | R | A | -2.6682 | |
| 158 | Q | A | -1.9430 | |
| 159 | S | A | 0.0000 | |
| 160 | L | A | -1.0387 | |
| 161 | E | A | -1.5378 | |
| 162 | I | A | 0.0000 | |
| 163 | I | A | 0.0000 | |
| 164 | S | A | 0.0000 | |
| 165 | R | A | -1.0267 | |
| 166 | Y | A | 0.0000 | |
| 167 | L | A | 0.0000 | |
| 168 | R | A | -1.7205 | |
| 169 | E | A | 0.0000 | |
| 170 | Q | A | 0.0000 | |
| 171 | A | A | -1.0341 | |
| 172 | T | A | -1.0559 | |
| 173 | G | A | -1.4824 | |
| 174 | S | A | -1.9774 | |
| 175 | K | A | -3.0959 | |
| 176 | D | A | -3.1625 | |
| 177 | S | A | -2.6920 | |
| 178 | K | A | -2.9555 | |
| 179 | P | A | -2.2235 | |
| 180 | L | A | 0.0000 | |
| 181 | G | A | -2.1058 | |
| 182 | E | A | -2.6767 | |
| 183 | A | A | 0.0000 | |
| 184 | G | A | -1.6162 | |
| 185 | A | A | -1.1145 | |
| 186 | A | A | -1.4819 | |
| 187 | G | A | 0.0000 | |
| 188 | R | A | -2.7059 | |
| 189 | R | A | -2.3902 | |
| 190 | A | A | 0.0000 | |
| 191 | L | A | 0.0000 | |
| 192 | E | A | -2.4984 | |
| 193 | T | A | 0.0000 | |
| 194 | L | A | 0.0000 | |
| 195 | R | A | -1.8565 | |
| 196 | R | A | -2.3921 | |
| 197 | V | A | 0.0000 | |
| 198 | G | A | 0.0000 | |
| 199 | D | A | -1.7024 | |
| 200 | G | A | -2.0105 | |
| 201 | V | A | 0.0000 | |
| 202 | Q | A | 0.0000 | |
| 203 | R | A | -3.1451 | |
| 204 | N | A | -2.6834 | |
| 205 | H | A | -2.2032 | |
| 206 | E | A | -2.4641 | |
| 207 | T | A | -1.3222 | |
| 208 | A | A | -1.2468 | |
| 209 | F | A | 0.0000 | |
| 210 | Q | A | -1.8869 | |
| 211 | G | A | -1.6887 | |
| 212 | M | A | 0.0000 | |
| 213 | L | A | 0.0000 | |
| 214 | R | A | -3.0994 | |
| 215 | K | A | -2.8688 | |
| 216 | L | A | 0.0000 | |
| 217 | D | A | -2.4159 | |
| 218 | I | A | 0.0000 | |
| 219 | K | A | -2.9447 | |
| 220 | N | A | -3.2153 | |
| 221 | E | A | -3.2831 | |
| 222 | G | A | -2.6138 | |
| 223 | D | A | -2.4773 | |
| 224 | V | A | -2.0465 | |
| 225 | K | A | -2.5215 | |
| 226 | S | A | -1.5322 | |
| 227 | F | A | 0.0000 | |
| 228 | S | A | -0.7253 | |
| 229 | R | A | -1.5912 | |
| 230 | V | A | 0.0000 | |
| 231 | M | A | 0.0000 | |
| 232 | V | A | 0.6056 | |
| 233 | H | A | 0.0000 | |
| 234 | V | A | 0.0000 | |
| 235 | F | A | -0.6159 | |
| 236 | K | A | -1.8810 | |
| 237 | D | A | -1.8343 | |
| 238 | G | A | -0.9493 | |
| 239 | V | A | -0.0127 | |
| 240 | T | A | -0.1455 | |
| 241 | N | A | 0.0013 | |
| 242 | W | A | 0.0000 | |
| 243 | G | A | 0.0000 | |
| 244 | R | A | 0.0000 | |
| 245 | I | A | 0.0000 | |
| 246 | V | A | 0.0000 | |
| 247 | T | A | 0.0000 | |
| 248 | L | A | 0.0000 | |
| 249 | I | A | 0.0000 | |
| 250 | S | A | 0.0000 | |
| 251 | F | A | 0.0000 | |
| 252 | G | A | 0.0000 | |
| 253 | A | A | 0.0000 | |
| 254 | F | A | -0.1197 | |
| 255 | V | A | 0.0000 | |
| 256 | A | A | 0.0000 | |
| 257 | K | A | -0.8373 | |
| 258 | H | A | -0.7775 | |
| 259 | L | A | 0.0000 | |
| 260 | K | A | -1.0721 | |
| 261 | S | A | -0.2713 | |
| 262 | V | A | 0.6313 | |
| 263 | N | A | -1.0935 | |
| 264 | Q | A | -1.3015 | |
| 265 | E | A | -1.7587 | |
| 266 | S | A | -1.2309 | |
| 267 | F | A | -1.4636 | |
| 268 | I | A | 0.0000 | |
| 269 | E | A | -1.6641 | |
| 270 | P | A | -1.1471 | |
| 271 | L | A | 0.0000 | |
| 272 | A | A | 0.0000 | |
| 273 | E | A | -1.2738 | |
| 274 | T | A | -0.8250 | |
| 275 | I | A | 0.0000 | |
| 276 | T | A | 0.0000 | |
| 277 | D | A | -0.9321 | |
| 278 | V | A | -0.3349 | |
| 279 | L | A | 0.0000 | |
| 280 | V | A | 0.0000 | |
| 281 | R | A | -1.6179 | |
| 282 | T | A | -0.9998 | |
| 283 | K | A | -1.6381 | |
| 284 | R | A | -2.6328 | |
| 285 | D | A | -2.0490 | |
| 286 | W | A | -1.6640 | |
| 287 | L | A | 0.0000 | |
| 288 | V | A | -0.8304 | |
| 289 | K | A | -2.0450 | |
| 290 | Q | A | -2.2281 | |
| 291 | R | A | -2.4968 | |
| 292 | G | A | 0.0000 | |
| 293 | W | A | 0.0000 | |
| 294 | D | A | -2.5128 | |
| 295 | G | A | 0.0000 | |
| 296 | F | A | 0.0000 | |
| 297 | V | A | 0.0000 | |
| 298 | E | A | -2.4482 | |
| 299 | F | A | -0.7761 | |
| 300 | F | A | 0.0000 | |
| 301 | H | A | -0.8887 | |
| 302 | V | A | -0.4321 | |
| 303 | Q | A | -1.0775 | |
| 304 | D | A | -1.3250 | |
| 305 | L | A | -0.1575 | |
| 306 | E | A | -1.8831 | |
| 307 | G | A | -1.1952 | |
| 308 | G | A | -0.9140 | |
| 130 | E | B | -2.5953 | |
| 131 | E | B | -2.6922 | |
| 132 | E | B | -3.1966 | |
| 133 | W | B | -2.1560 | |
| 134 | A | B | 0.0000 | |
| 135 | R | B | -3.2863 | |
| 136 | E | B | -2.4690 | |
| 137 | I | B | 0.0000 | |
| 138 | G | B | 0.0000 | |
| 139 | A | B | -1.7824 | |
| 140 | Q | B | -1.5574 | |
| 141 | L | B | 0.0000 | |
| 142 | R | B | -2.2996 | |
| 143 | R | B | -2.6118 | |
| 144 | I | B | -1.6605 | |
| 145 | A | B | 0.0000 | |
| 146 | D | B | -1.9403 | |
| 147 | D | B | -2.5319 | |
| 148 | L | B | -1.3248 | |
| 149 | N | B | 0.0000 | |
| 150 | A | B | -1.9994 | |
| 151 | Q | B | -1.9436 | |
| 152 | Y | B | -1.5526 | |
| 153 | E | B | -1.9843 | |
| 154 | R | B | -2.8564 | |
| 155 | R | B | -2.4080 | |
| 156 | M | B | -0.5297 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine