Project name: 5vkk:L

Chain sequence(s)	L: DIQLTQSPSSLSASVGDRVTMSCKSSQSVLYSANHKNYLAWYQQKPGKAPKLLIYWASTRESGVPSRFSGSGSGTDFTLTISSLQPEDIATYYCHQYLSSWTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.7027
• Maximal score value: 1.5806
• Average score: -0.8126
• Total score value: -177.9554

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-2.2209
2	I	L	0.0000
3	Q	L	-1.8772
4	L	L	0.0000
5	T	L	-0.9872
6	Q	L	-0.5413
7	S	L	-0.8011
8	P	L	-0.6845
9	S	L	-0.9625
10	S	L	-1.0712
11	L	L	-0.7967
12	S	L	-1.0585
13	A	L	-1.1749
14	S	L	-1.0358
15	V	L	-0.3736
16	G	L	-0.9367
17	D	L	-1.9182
18	R	L	-2.4038
19	V	L	0.0000
20	T	L	-0.5983
21	M	L	0.0000
22	S	L	-0.7939
23	C	L	0.0000
24	K	L	-2.2195
25	S	L	0.0000
26	S	L	-1.9354
27	Q	L	-2.1137
27A	S	L	-0.8604
27B	V	L	0.0000
27C	L	L	0.0654
27D	Y	L	0.3283
27E	S	L	-0.3047
27F	A	L	-0.4205
28	N	L	-1.0890
29	H	L	-1.3190
30	K	L	-1.0108
31	N	L	-0.2137
32	Y	L	0.4567
33	L	L	0.0000
34	A	L	0.0000
35	W	L	0.0000
36	Y	L	-0.0935
37	Q	L	0.0000
38	Q	L	-1.4506
39	K	L	-1.6567
40	P	L	-1.5197
41	G	L	-1.5583
42	K	L	-2.3998
43	A	L	-1.4164
44	P	L	-1.3005
45	K	L	-1.5651
46	L	L	-0.4273
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	0.2719
50	W	L	0.1423
51	A	L	0.0000
52	S	L	-0.5524
53	T	L	-0.4445
54	R	L	-1.0441
55	E	L	-1.1132
56	S	L	-0.8230
57	G	L	-0.7509
58	V	L	-0.7053
59	P	L	-0.5678
60	S	L	-0.7027
61	R	L	-0.8781
62	F	L	0.0000
63	S	L	-0.6295
64	G	L	-0.4275
65	S	L	-0.7096
66	G	L	-1.1631
67	S	L	-1.0049
68	G	L	-0.9985
69	T	L	-1.6067
70	D	L	-2.3725
71	F	L	0.0000
72	T	L	-0.7901
73	L	L	0.0000
74	T	L	-0.6214
75	I	L	0.0000
76	S	L	-1.4666
77	S	L	-1.3053
78	L	L	0.0000
79	Q	L	-1.1640
80	P	L	-1.4761
81	E	L	-2.0990
82	D	L	0.0000
83	I	L	-1.2951
84	A	L	0.0000
85	T	L	-0.9647
86	Y	L	0.0000
87	Y	L	0.0629
88	C	L	0.0000
89	H	L	0.0000
90	Q	L	0.0000
91	Y	L	1.0427
92	L	L	0.8847
93	S	L	0.1642
94	S	L	0.1673
96	W	L	1.1289
97	T	L	0.5423
98	F	L	1.1566
99	G	L	0.0000
100	G	L	-0.5615
101	G	L	0.0000
102	T	L	0.0000
103	K	L	-1.9238
104	L	L	0.0000
105	E	L	-1.6264
106	I	L	0.0000
107	K	L	-1.7749
108	R	L	-1.0045
109	T	L	-0.2195
110	V	L	0.1521
112	A	L	-0.1879
113	A	L	-0.2480
114	P	L	0.0000
115	S	L	-0.0343
116	V	L	0.3661
117	F	L	1.2250
118	I	L	1.2162
119	F	L	1.5806
120	P	L	0.0654
121	P	L	-0.5205
122	S	L	-1.6622
123	D	L	-3.2514
124	E	L	-3.4426
125	Q	L	-2.4163
126	L	L	-2.2552
127	K	L	-3.0249
128	S	L	-1.9370
129	G	L	-1.4382
130	T	L	-1.1018
131	A	L	0.0000
132	S	L	0.0398
133	V	L	0.0000
134	V	L	0.7072
135	C	L	0.0000
136	L	L	0.5082
137	L	L	0.0000
138	N	L	-0.6189
139	N	L	-1.2698
140	F	L	0.0000
141	Y	L	0.0000
142	P	L	-1.9627
143	R	L	-3.1932
144	E	L	-3.2873
145	A	L	-2.3906
146	K	L	-2.4516
147	V	L	-1.1177
148	Q	L	-0.5659
149	W	L	0.0000
150	K	L	-0.6058
151	V	L	0.0000
152	D	L	-1.9127
153	N	L	-1.5392
154	A	L	-0.3149
155	L	L	0.5944
156	Q	L	-0.1555
157	S	L	-0.5445
158	G	L	-1.0035
159	N	L	-0.9557
160	S	L	-1.4205
161	Q	L	-2.3321
162	E	L	-2.3505
163	S	L	-1.3442
164	V	L	-0.7456
165	T	L	-1.2838
166	E	L	-2.3126
167	Q	L	0.0000
168	D	L	-2.3780
169	S	L	-2.3419
170	K	L	-2.5518
171	D	L	-1.7752
172	S	L	-1.9622
173	T	L	0.0000
174	Y	L	0.0000
175	S	L	-1.0545
176	L	L	0.0000
177	S	L	-0.5529
178	S	L	0.0000
179	T	L	-0.6363
180	L	L	0.0000
181	T	L	-0.4716
182	L	L	-0.6548
183	S	L	-1.1642
184	K	L	-2.0123
185	A	L	-1.8483
186	D	L	-2.4112
187	Y	L	0.0000
188	E	L	-3.7027
189	K	L	-3.6891
190	H	L	-3.0295
191	K	L	-3.3441
192	V	L	-1.5018
193	Y	L	0.0000
194	A	L	0.0000
195	C	L	0.0000
196	E	L	-0.6986
197	V	L	0.0000
198	T	L	-1.2203
199	H	L	0.0000
200	Q	L	-1.8174
201	G	L	-0.5008
202	L	L	-0.2825
203	S	L	-0.4750
204	S	L	-0.4286
205	P	L	-0.5318
206	V	L	0.0292
207	T	L	-0.4028
208	K	L	-0.4753
209	S	L	-0.4760
210	F	L	0.0000
211	N	L	-2.0097
212	R	L	-2.6451
213	G	L	-2.0762
214	E	L	-2.2315
215	C	L	-0.4026