Project name: GCSF
Status: done
submitted: 2019-01-10 12:51:04, status changed: 2019-01-10 12:58:38
Settings
|
Chain sequence(s)
|
X: MTPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLCATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSYRVLRHLAQP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-3.0602
-
Maximal score value
-
1.6194
-
Average score
-
-0.5946
-
Total score value
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-104.0518
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
M |
X |
1.0993 |
|
| 2 |
T |
X |
0.5212 |
|
| 3 |
P |
X |
0.5924 |
|
| 4 |
L |
X |
1.2901 |
|
| 5 |
G |
X |
0.3152 |
|
| 6 |
P |
X |
0.0350 |
|
| 7 |
A |
X |
0.0606 |
|
| 8 |
S |
X |
-0.3610 |
|
| 9 |
S |
X |
-0.0808 |
|
| 10 |
L |
X |
0.0000 |
|
| 11 |
P |
X |
-0.6015 |
|
| 12 |
Q |
X |
-1.4831 |
|
| 13 |
S |
X |
-0.8681 |
|
| 14 |
F |
X |
0.0000 |
|
| 15 |
L |
X |
0.0000 |
|
| 16 |
L |
X |
-0.7955 |
|
| 17 |
K |
X |
-1.5838 |
|
| 18 |
C |
X |
0.0000 |
|
| 19 |
L |
X |
0.0000 |
|
| 20 |
E |
X |
-2.4535 |
|
| 21 |
Q |
X |
-2.3506 |
|
| 22 |
V |
X |
0.0000 |
|
| 23 |
R |
X |
-2.9767 |
|
| 24 |
K |
X |
-3.0602 |
|
| 25 |
I |
X |
0.0000 |
|
| 26 |
Q |
X |
-2.0019 |
|
| 27 |
G |
X |
-1.6656 |
|
| 28 |
D |
X |
-1.6645 |
|
| 29 |
G |
X |
-1.2916 |
|
| 30 |
A |
X |
-1.2608 |
|
| 31 |
A |
X |
-1.1722 |
|
| 32 |
L |
X |
0.0000 |
|
| 33 |
Q |
X |
-1.5303 |
|
| 34 |
E |
X |
-2.4038 |
|
| 35 |
K |
X |
-2.0862 |
|
| 36 |
L |
X |
0.0000 |
|
| 37 |
C |
X |
-1.3991 |
|
| 38 |
A |
X |
-1.0576 |
|
| 39 |
T |
X |
-1.0336 |
|
| 40 |
Y |
X |
-0.6261 |
|
| 41 |
K |
X |
-1.7269 |
|
| 42 |
L |
X |
-1.2514 |
|
| 43 |
C |
X |
-1.4808 |
|
| 44 |
H |
X |
-1.9959 |
|
| 45 |
P |
X |
-1.3507 |
|
| 46 |
E |
X |
-2.1657 |
|
| 47 |
E |
X |
-2.1184 |
|
| 48 |
L |
X |
0.0000 |
|
| 49 |
V |
X |
1.0541 |
|
| 50 |
L |
X |
1.6194 |
|
| 51 |
L |
X |
0.8190 |
|
| 52 |
G |
X |
0.5477 |
|
| 53 |
H |
X |
-0.4398 |
|
| 54 |
S |
X |
-0.0916 |
|
| 55 |
L |
X |
-0.1690 |
|
| 56 |
G |
X |
-0.5207 |
|
| 57 |
I |
X |
0.0000 |
|
| 58 |
P |
X |
0.3064 |
|
| 59 |
W |
X |
1.0338 |
|
| 60 |
A |
X |
0.0000 |
|
| 61 |
P |
X |
0.1869 |
|
| 62 |
L |
X |
0.0082 |
|
| 63 |
S |
X |
-0.3512 |
|
| 64 |
S |
X |
-0.4730 |
|
| 65 |
C |
X |
0.0000 |
|
| 66 |
P |
X |
-0.7508 |
|
| 67 |
S |
X |
-0.7765 |
|
| 68 |
Q |
X |
-0.8478 |
|
| 69 |
A |
X |
-0.3589 |
|
| 70 |
L |
X |
0.1716 |
|
| 71 |
Q |
X |
-0.9859 |
|
| 72 |
L |
X |
0.0000 |
|
| 73 |
A |
X |
-0.3598 |
|
| 74 |
G |
X |
-0.6030 |
|
| 75 |
C |
X |
0.0000 |
|
| 76 |
L |
X |
0.0000 |
|
| 77 |
S |
X |
-0.2565 |
|
| 78 |
Q |
X |
-0.3753 |
|
| 79 |
L |
X |
0.0000 |
|
| 80 |
H |
X |
0.0000 |
|
| 81 |
S |
X |
-0.4375 |
|
| 82 |
G |
X |
0.0000 |
|
| 83 |
L |
X |
0.0000 |
|
| 84 |
F |
X |
-0.2477 |
|
| 85 |
L |
X |
-0.0688 |
|
| 86 |
Y |
X |
0.0000 |
|
| 87 |
Q |
X |
-0.6828 |
|
| 88 |
G |
X |
-0.6952 |
|
| 89 |
L |
X |
0.0000 |
|
| 90 |
L |
X |
0.0000 |
|
| 91 |
Q |
X |
-1.8238 |
|
| 92 |
A |
X |
-1.2613 |
|
| 93 |
L |
X |
0.0000 |
|
| 94 |
E |
X |
-2.4368 |
|
| 95 |
G |
X |
-1.9934 |
|
| 96 |
I |
X |
0.0000 |
|
| 97 |
S |
X |
-1.2978 |
|
| 98 |
P |
X |
-1.2634 |
|
| 99 |
E |
X |
-2.1675 |
|
| 100 |
L |
X |
0.0000 |
|
| 101 |
G |
X |
-1.4605 |
|
| 102 |
P |
X |
-1.1117 |
|
| 103 |
T |
X |
-1.0600 |
|
| 104 |
L |
X |
0.0000 |
|
| 105 |
D |
X |
-1.2681 |
|
| 106 |
T |
X |
-0.3659 |
|
| 107 |
L |
X |
0.0000 |
|
| 108 |
Q |
X |
-0.6604 |
|
| 109 |
L |
X |
0.2771 |
|
| 110 |
D |
X |
-0.9676 |
|
| 111 |
V |
X |
0.0000 |
|
| 112 |
A |
X |
-0.5469 |
|
| 113 |
D |
X |
-1.5887 |
|
| 114 |
F |
X |
0.0000 |
|
| 115 |
A |
X |
0.0000 |
|
| 116 |
T |
X |
-1.0064 |
|
| 117 |
T |
X |
-1.0451 |
|
| 118 |
I |
X |
0.0000 |
|
| 119 |
W |
X |
-1.4922 |
|
| 120 |
Q |
X |
-2.2225 |
|
| 121 |
Q |
X |
0.0000 |
|
| 122 |
M |
X |
0.0000 |
|
| 123 |
E |
X |
-3.0104 |
|
| 124 |
E |
X |
-2.7839 |
|
| 125 |
L |
X |
-1.1196 |
|
| 126 |
G |
X |
-1.4284 |
|
| 127 |
M |
X |
-0.8947 |
|
| 128 |
A |
X |
-1.0319 |
|
| 129 |
P |
X |
-0.1149 |
|
| 130 |
A |
X |
0.4687 |
|
| 131 |
L |
X |
0.9316 |
|
| 132 |
Q |
X |
-0.6781 |
|
| 133 |
P |
X |
-0.6497 |
|
| 134 |
T |
X |
-0.7222 |
|
| 135 |
Q |
X |
-1.3991 |
|
| 136 |
G |
X |
-0.4605 |
|
| 137 |
A |
X |
-0.1948 |
|
| 138 |
M |
X |
-0.0648 |
|
| 139 |
P |
X |
0.0497 |
|
| 140 |
A |
X |
0.0106 |
|
| 141 |
F |
X |
0.0000 |
|
| 142 |
A |
X |
0.1053 |
|
| 143 |
S |
X |
0.1280 |
|
| 144 |
A |
X |
0.2876 |
|
| 145 |
F |
X |
0.8780 |
|
| 146 |
Q |
X |
0.0649 |
|
| 147 |
R |
X |
-0.7046 |
|
| 148 |
R |
X |
-0.2366 |
|
| 149 |
A |
X |
0.0000 |
|
| 150 |
G |
X |
0.0000 |
|
| 151 |
G |
X |
0.0000 |
|
| 152 |
V |
X |
0.0000 |
|
| 153 |
L |
X |
0.0000 |
|
| 154 |
V |
X |
0.0000 |
|
| 155 |
A |
X |
0.0000 |
|
| 156 |
S |
X |
-0.5316 |
|
| 157 |
H |
X |
-0.3020 |
|
| 158 |
L |
X |
0.0000 |
|
| 159 |
Q |
X |
-0.8171 |
|
| 160 |
S |
X |
-0.4976 |
|
| 161 |
F |
X |
0.0000 |
|
| 162 |
L |
X |
0.0000 |
|
| 163 |
E |
X |
-1.3097 |
|
| 164 |
V |
X |
-0.2458 |
|
| 165 |
S |
X |
0.0000 |
|
| 166 |
Y |
X |
-1.6383 |
|
| 167 |
R |
X |
-2.4200 |
|
| 168 |
V |
X |
0.0000 |
|
| 169 |
L |
X |
0.0000 |
|
| 170 |
R |
X |
-2.5221 |
|
| 171 |
H |
X |
-2.5031 |
|
| 172 |
L |
X |
-1.5272 |
|
| 173 |
A |
X |
0.0000 |
|
| 174 |
Q |
X |
-1.9892 |
|
| 175 |
P |
X |
-0.6866 |
|