Project name: 6b9z:B

Chain sequence(s)	B: EVQLVESGGGLVVQPGGSLRLSCAASGFNNIKDTYIHWVRQSPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAIYYCCSRWGGDGFYAMDYWGQGTLVTVSSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPCVLQSSGLYSSLSSVVTTVPSSSSLGTQTYICNVNNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8928
• Maximal score value: 2.471
• Average score: -0.5928
• Total score value: -130.4117

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.0975
2	V	B	-1.3102
3	Q	B	-1.1595
4	L	B	0.0000
5	V	B	0.2192
6	E	B	0.0000
7	S	B	-0.5713
8	G	B	-0.9149
9	G	B	-0.4809
10	G	B	-0.5229
11	L	B	-0.0804
12	V	B	-0.6171
13	Q	B	-1.5621
14	P	B	-1.6273
15	G	B	-1.3951
16	G	B	-1.0848
17	S	B	-1.1236
18	L	B	-0.9756
19	R	B	-1.9373
20	L	B	0.0000
21	S	B	-0.4356
22	C	B	0.0000
23	A	B	-0.3185
24	A	B	0.0000
25	S	B	-1.1795
26	G	B	-1.3763
27	F	B	-1.4959
28	N	B	-2.0030
29	I	B	0.0000
30	K	B	-2.5766
31	D	B	-2.7753
32	T	B	0.0000
33	Y	B	0.1143
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.4562
40	S	B	-1.0964
41	P	B	-1.0304
42	G	B	-1.4151
43	K	B	-2.1226
44	G	B	-1.0310
45	L	B	0.4138
46	E	B	-0.6187
47	W	B	-0.0130
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-1.0196
51	I	B	0.0000
52	Y	B	-0.4344
53	P	B	-1.0681
54	T	B	-1.1864
55	N	B	-0.8385
56	G	B	-0.4396
57	Y	B	0.4233
58	T	B	-0.6439
59	R	B	-2.1711
60	Y	B	-1.9492
61	A	B	-1.9104
62	D	B	-2.6815
63	S	B	-1.6280
64	V	B	0.0000
65	K	B	-2.8928
66	G	B	-1.8132
67	R	B	-1.4518
68	F	B	0.0000
69	T	B	-1.1462
70	I	B	0.0000
71	S	B	-0.1875
72	A	B	-0.7638
73	D	B	-1.4212
74	T	B	-1.5448
75	S	B	-1.5224
76	K	B	-2.1913
77	N	B	-1.7186
78	T	B	-0.8914
79	A	B	0.0000
80	Y	B	-0.3884
81	L	B	0.0000
82	Q	B	-1.0888
83	M	B	0.0000
84	N	B	-1.4700
85	S	B	-1.2940
86	L	B	0.0000
87	R	B	-2.2222
88	A	B	-1.6920
89	E	B	-2.2055
90	D	B	0.0000
91	T	B	-0.7156
92	A	B	0.0000
93	I	B	0.5739
94	Y	B	0.0000
95	Y	B	0.4047
96	C	B	0.0000
97	S	B	0.0000
98	R	B	0.0000
99	W	B	0.7101
100	G	B	0.4279
101	G	B	0.0000
102	D	B	-1.5227
103	G	B	-0.2097
104	F	B	1.7751
105	Y	B	1.9605
106	A	B	1.2798
107	M	B	0.9337
108	D	B	0.2762
109	Y	B	0.2087
110	W	B	0.3089
111	G	B	-0.2257
112	Q	B	-0.9044
113	G	B	-0.2396
114	T	B	-0.0695
115	L	B	0.0325
116	V	B	0.0000
117	T	B	-0.4661
118	V	B	0.0000
119	S	B	-0.9362
120	S	B	-0.6771
121	A	B	-0.4667
122	S	B	-0.6075
123	T	B	-0.7352
124	K	B	-1.3885
125	G	B	-1.6110
126	P	B	-0.6900
127	S	B	-0.2036
128	V	B	0.0000
129	F	B	0.9714
130	P	B	0.1941
131	L	B	0.4283
132	A	B	-1.0238
133	P	B	0.0000
134	S	B	-1.3634
135	S	B	-1.1879
136	K	B	-1.9213
137	S	B	-1.0098
138	T	B	-1.0126
139	S	B	-0.9480
140	G	B	-0.8560
141	G	B	-0.9160
142	T	B	-0.6278
143	A	B	0.0000
144	A	B	-0.2040
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.7779
149	V	B	0.0000
150	K	B	-0.3185
151	D	B	-0.5686
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.8218
156	P	B	-0.9346
157	V	B	-0.5127
158	T	B	-0.4850
159	V	B	-0.0790
160	S	B	-0.3645
161	W	B	0.0000
162	N	B	-0.7814
163	S	B	-0.6872
164	G	B	-0.5736
165	A	B	-0.2479
166	L	B	-0.0313
167	T	B	-0.3038
168	S	B	-0.3708
169	G	B	-0.4825
170	V	B	-0.0184
171	H	B	-0.5384
172	T	B	0.0978
173	F	B	0.7897
174	P	B	0.6546
176	V	B	2.4710
177	L	B	2.1324
178	Q	B	0.7094
179	S	B	0.1027
180	S	B	-0.2205
181	G	B	0.2265
182	L	B	0.1768
183	Y	B	0.7431
184	S	B	0.6828
185	L	B	0.9215
186	S	B	0.6729
187	S	B	0.0000
188	V	B	0.3824
189	V	B	0.0000
190	T	B	-0.2430
191	V	B	0.0000
192	P	B	-0.6061
193	S	B	-0.5581
194	S	B	-0.5087
195	S	B	-0.4763
196	L	B	-0.6555
197	G	B	-1.0389
198	T	B	-0.8324
199	Q	B	-1.1664
200	T	B	-1.1162
201	Y	B	0.0000
202	I	B	-1.3935
203	C	B	0.0000
204	N	B	-1.4720
205	V	B	0.0000
206	N	B	-1.7394
207	H	B	0.0000
208	K	B	-2.8110
209	P	B	-1.7174
210	S	B	-1.8811
211	N	B	-2.5633
212	T	B	-2.0811
213	K	B	-2.6679
214	V	B	-1.6741
215	D	B	-2.5678
216	K	B	-2.1098
217	K	B	-2.5018
218	V	B	0.0000
219	E	B	-2.8099
220	P	B	-1.8688
221	K	B	-2.1877