Project name: f1618e2ff01d1c9

Chain sequence(s)	A: GSSSHHVVPNEVVVVQRLFQQVKGRRVVRATTEEVPVSWEESFKNGDCFILDLGNNIHQWCGSNSNRRYERRLKKATQVSKGIRDNERSSGRRARRVHVSEEEEGGTEPEEAMLQQVLGPKKPALPAGTTEDT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8065
• Maximal score value: 2.7103
• Average score: -0.9304
• Total score value: -105.1305

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
148	G	A	-1.0915
149	S	A	-0.9600
150	H	A	-1.0173
151	H	A	-0.4209
152	V	A	1.6381
153	V	A	1.5790
154	P	A	0.0897
155	N	A	-1.1171
156	E	A	-0.8001
157	V	A	1.7978
158	V	A	2.7103
159	V	A	2.5428
160	Q	A	1.1701
161	R	A	-0.2907
162	L	A	0.0000
163	F	A	-0.7760
164	Q	A	-0.8742
165	V	A	0.0000
166	K	A	-1.5578
167	G	A	0.0000
168	R	A	-3.0250
169	R	A	-2.2705
170	V	A	-0.0405
171	V	A	-0.9839
172	R	A	-2.0466
173	A	A	-1.3096
174	T	A	-1.2957
175	E	A	-1.8679
176	V	A	-0.8257
177	P	A	-0.5937
178	V	A	0.0181
179	S	A	-0.3793
180	W	A	0.0000
181	E	A	-1.8769
182	S	A	-1.0762
183	F	A	0.0000
184	K	A	-1.0886
185	N	A	-1.1353
186	G	A	-1.3818
187	D	A	0.0000
188	C	A	0.0000
189	F	A	0.0000
190	I	A	0.0000
191	L	A	0.0000
192	D	A	0.0000
193	L	A	0.0562
194	G	A	-1.0076
195	N	A	-2.3611
196	N	A	-2.1499
197	I	A	0.0000
198	H	A	0.0000
199	Q	A	0.0000
200	W	A	0.0000
201	C	A	-1.0636
202	G	A	0.0000
203	S	A	-1.4443
204	N	A	-1.7781
205	S	A	0.0000
206	N	A	-2.1528
207	R	A	-2.5539
208	Y	A	-1.2122
209	E	A	0.0000
210	R	A	-1.5004
211	L	A	-0.2281
212	K	A	-0.9254
213	A	A	0.0000
214	T	A	-0.3843
215	Q	A	-1.0421
216	V	A	-0.9549
217	S	A	0.0000
218	K	A	-2.5184
219	G	A	-2.1928
220	I	A	0.0000
221	R	A	-3.8065
222	D	A	-3.5944
223	N	A	-3.4990
224	E	A	-3.6494
225	R	A	-3.6063
226	S	A	-2.6390
227	G	A	-3.2889
228	R	A	-3.6794
229	A	A	-3.3959
230	R	A	-2.8516
231	V	A	-0.9989
232	H	A	0.0940
233	V	A	1.0728
234	S	A	-0.3355
235	E	A	-1.9009
236	E	A	-1.7847
237	G	A	-1.3916
238	T	A	-1.1375
239	E	A	-1.1282
240	P	A	-1.1531
241	E	A	-1.9101
242	A	A	-1.0296
243	M	A	0.0000
244	L	A	-0.6675
245	Q	A	-1.1502
246	V	A	0.0074
247	L	A	-0.1939
248	G	A	-0.5348
249	P	A	-0.5910
250	K	A	-1.0211
251	P	A	-0.7473
252	A	A	-0.2786
253	L	A	-0.5870
254	P	A	-0.5986
255	A	A	-0.9078
256	G	A	-1.1084
257	T	A	-1.3223
258	E	A	-2.4164
259	D	A	-2.1239
260	T	A	-1.3048