Project name: 5ir1:A

Chain sequence(s)	A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEEDIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADDYEKHKVYACEVTHQGLSSPVTKSFNRGA
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8812
• Maximal score value: 1.7481
• Average score: -0.8387
• Total score value: -178.6339

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-1.4316
2	I	A	0.0000
3	L	A	0.7898
4	L	A	0.0000
5	T	A	-0.2309
6	Q	A	0.0000
7	S	A	0.0866
8	P	A	0.7790
9	V	A	1.7481
10	I	A	1.1006
11	L	A	0.4288
12	S	A	-0.3802
13	V	A	-1.2460
14	S	A	-1.7130
15	P	A	-2.0537
16	G	A	-2.1662
17	E	A	-2.9084
18	R	A	-3.1934
19	V	A	0.0000
20	S	A	-0.7702
21	F	A	0.0000
22	S	A	-0.8436
23	C	A	0.0000
24	R	A	-2.6167
25	A	A	-1.4702
26	S	A	-1.1499
27	Q	A	-1.8338
28	S	A	-1.6599
29	I	A	0.0000
30	G	A	-1.0565
31	T	A	-0.7387
32	N	A	-0.9569
33	I	A	0.0000
34	H	A	-0.2184
35	W	A	0.0000
36	Y	A	-0.0585
37	Q	A	0.0000
38	Q	A	-1.5061
39	R	A	-2.0452
40	T	A	-1.7963
41	N	A	-1.7268
42	G	A	-1.4571
43	S	A	-1.0240
44	P	A	-0.9623
45	R	A	-0.6625
46	L	A	-0.0833
47	L	A	0.0000
48	I	A	0.0000
49	K	A	-0.7662
50	Y	A	-0.1066
51	A	A	0.0000
52	S	A	-1.0988
53	E	A	-1.8423
54	S	A	-1.0533
55	I	A	-0.4647
56	S	A	-0.2466
57	G	A	-0.3946
58	I	A	-0.1280
59	P	A	-0.2855
60	S	A	-0.5223
61	R	A	-1.0524
62	F	A	0.0000
63	S	A	-0.9129
64	G	A	-0.6959
65	S	A	-0.8001
66	G	A	-1.1361
67	S	A	-1.1190
68	G	A	-1.4357
69	T	A	-2.0926
70	D	A	-2.8384
71	F	A	0.0000
72	T	A	-0.9421
73	L	A	0.0000
74	S	A	-0.8922
75	I	A	0.0000
76	N	A	-2.3117
77	S	A	-2.2393
78	V	A	0.0000
79	E	A	-2.6243
80	S	A	-2.3423
81	E	A	-2.2434
82	D	A	0.0000
83	I	A	-1.6673
84	A	A	0.0000
85	D	A	-0.9727
86	Y	A	0.0000
87	Y	A	0.1829
88	C	A	0.0000
89	Q	A	0.3740
90	Q	A	0.0000
91	N	A	-1.2173
92	N	A	-1.6591
93	N	A	-1.2872
94	W	A	0.0801
95	P	A	-0.1090
96	T	A	-0.3925
97	T	A	0.4385
98	F	A	1.6556
99	G	A	0.0000
100	A	A	0.7141
101	G	A	0.3890
102	T	A	0.0000
103	K	A	-0.4053
104	L	A	0.0000
105	E	A	-1.2113
106	L	A	0.0000
107	K	A	-1.4762
108	R	A	-1.1148
109	T	A	-0.1838
110	V	A	0.1171
111	A	A	-0.2512
112	A	A	-0.2739
113	P	A	0.0000
114	S	A	-0.1622
115	V	A	0.0000
116	F	A	1.0791
117	I	A	1.1987
118	F	A	1.5768
119	P	A	0.0468
120	P	A	0.0000
121	S	A	-1.7919
122	D	A	-3.2428
123	E	A	-3.4525
124	Q	A	-2.6034
125	L	A	-2.7021
126	K	A	-3.0697
127	S	A	-1.9581
128	G	A	-1.4898
129	T	A	-1.2878
130	A	A	0.0000
131	S	A	0.0290
132	V	A	0.0000
133	V	A	0.7494
134	C	A	0.0000
135	L	A	0.4681
136	L	A	0.0000
137	N	A	-0.5626
138	N	A	-1.3555
139	F	A	0.0000
140	Y	A	0.0000
141	P	A	-1.8311
142	R	A	-3.0006
143	E	A	-3.2476
144	A	A	-2.2818
145	K	A	-2.1316
146	V	A	-0.9817
147	Q	A	-0.6864
148	W	A	0.0000
149	K	A	-0.5861
150	V	A	0.0000
151	D	A	-1.7865
152	N	A	-1.4411
153	A	A	-0.2080
154	L	A	0.7460
155	Q	A	-0.1494
156	S	A	-0.4383
157	G	A	-1.0738
158	N	A	-1.1197
159	S	A	-1.4731
160	Q	A	-2.3268
161	E	A	-2.3295
162	S	A	-1.3488
163	V	A	-0.8768
164	T	A	-1.2907
165	E	A	-2.3727
166	Q	A	0.0000
167	D	A	-2.5004
168	S	A	-2.5906
169	K	A	-2.8308
170	D	A	-2.1716
171	S	A	0.0000
172	T	A	0.0000
173	Y	A	0.0000
174	S	A	-1.0438
175	L	A	0.0000
176	S	A	-0.4668
177	S	A	0.0000
178	T	A	-0.6096
179	L	A	0.0000
180	T	A	-0.6121
181	L	A	-0.8603
182	S	A	-1.2725
183	K	A	-2.4716
184	A	A	-2.1636
185	D	A	-2.8355
186	Y	A	0.0000
187	E	A	-3.8812
188	K	A	-3.8530
189	H	A	-3.1549
190	K	A	-3.1874
191	V	A	-1.4452
192	Y	A	0.0000
193	A	A	0.0000
194	C	A	0.0000
195	E	A	-0.8578
196	V	A	0.0000
197	T	A	-1.1635
198	H	A	0.0000
199	Q	A	-1.7857
200	G	A	-0.4782
201	L	A	-0.1971
202	S	A	-0.4243
203	S	A	-0.4066
204	P	A	-0.6233
205	V	A	0.0030
206	T	A	-0.3616
207	K	A	-0.4107
208	S	A	-0.3390
209	F	A	-0.5750
210	N	A	-1.7078
211	R	A	-2.4738
212	G	A	-1.4635
213	A	A	-0.7665