Project name: 5id0:A
Status: done
submitted: 2019-03-20 20:30:30, status changed: 2019-03-20 20:43:23
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7494
-
Maximal score value
-
1.8126
-
Average score
-
-0.8265
-
Total score value
-
-175.211
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.3893 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.8124 |
|
| 4 |
L |
A |
0.0211 |
|
| 5 |
T |
A |
-0.2740 |
|
| 6 |
Q |
A |
0.0955 |
|
| 7 |
S |
A |
0.0757 |
|
| 8 |
P |
A |
0.8024 |
|
| 9 |
V |
A |
1.8126 |
|
| 10 |
I |
A |
1.2204 |
|
| 11 |
L |
A |
0.5247 |
|
| 12 |
S |
A |
-0.3748 |
|
| 13 |
V |
A |
-1.1202 |
|
| 14 |
S |
A |
-1.6784 |
|
| 15 |
P |
A |
-1.8855 |
|
| 16 |
G |
A |
-2.0464 |
|
| 17 |
E |
A |
-2.8187 |
|
| 18 |
R |
A |
-3.1325 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.6930 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.8487 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.6137 |
|
| 25 |
A |
A |
-1.3842 |
|
| 26 |
S |
A |
-1.0533 |
|
| 27 |
Q |
A |
-1.6720 |
|
| 28 |
S |
A |
-1.6198 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0590 |
|
| 31 |
T |
A |
-0.7450 |
|
| 32 |
N |
A |
-0.9197 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.2874 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.4790 |
|
| 39 |
R |
A |
-1.8714 |
|
| 40 |
T |
A |
-1.6799 |
|
| 41 |
N |
A |
-1.6602 |
|
| 42 |
G |
A |
-1.4899 |
|
| 43 |
S |
A |
-1.1516 |
|
| 44 |
P |
A |
-1.2577 |
|
| 45 |
R |
A |
-1.4265 |
|
| 46 |
L |
A |
-0.4434 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.8048 |
|
| 50 |
Y |
A |
-0.1753 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1363 |
|
| 53 |
E |
A |
-1.9245 |
|
| 54 |
S |
A |
-1.1098 |
|
| 55 |
I |
A |
-0.4987 |
|
| 56 |
S |
A |
-0.4225 |
|
| 57 |
G |
A |
-0.3818 |
|
| 58 |
I |
A |
-0.2032 |
|
| 59 |
P |
A |
-0.3070 |
|
| 60 |
S |
A |
-0.5361 |
|
| 61 |
R |
A |
-1.0089 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.9182 |
|
| 64 |
G |
A |
-0.6920 |
|
| 65 |
S |
A |
-0.8076 |
|
| 66 |
G |
A |
-1.1026 |
|
| 67 |
S |
A |
-1.1367 |
|
| 68 |
G |
A |
-1.4296 |
|
| 69 |
T |
A |
-2.0663 |
|
| 70 |
D |
A |
-2.8719 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9425 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.8483 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.2565 |
|
| 77 |
S |
A |
-2.1843 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.4021 |
|
| 80 |
S |
A |
-2.3796 |
|
| 81 |
E |
A |
-2.4148 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
0.0000 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.8455 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.0891 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.3459 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.2828 |
|
| 92 |
N |
A |
-1.7009 |
|
| 93 |
N |
A |
-1.1867 |
|
| 94 |
W |
A |
0.0576 |
|
| 95 |
P |
A |
-0.1295 |
|
| 96 |
T |
A |
-0.4164 |
|
| 97 |
T |
A |
0.3581 |
|
| 98 |
F |
A |
1.4983 |
|
| 99 |
G |
A |
0.6994 |
|
| 100 |
A |
A |
0.7009 |
|
| 101 |
G |
A |
0.3138 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.3926 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.1187 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.5222 |
|
| 108 |
R |
A |
-1.0888 |
|
| 109 |
T |
A |
-0.1338 |
|
| 110 |
V |
A |
0.2257 |
|
| 111 |
A |
A |
-0.1558 |
|
| 112 |
A |
A |
-0.2329 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1162 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.4172 |
|
| 117 |
I |
A |
1.3612 |
|
| 118 |
F |
A |
1.5668 |
|
| 119 |
P |
A |
-0.0136 |
|
| 120 |
P |
A |
-0.6971 |
|
| 121 |
S |
A |
-1.8349 |
|
| 122 |
D |
A |
-3.2323 |
|
| 123 |
E |
A |
-3.4260 |
|
| 124 |
Q |
A |
-2.4410 |
|
| 125 |
L |
A |
-2.5414 |
|
| 126 |
K |
A |
-2.9879 |
|
| 127 |
S |
A |
-1.8545 |
|
| 128 |
G |
A |
-1.2535 |
|
| 129 |
T |
A |
-1.1179 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0643 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.8183 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.5525 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.6393 |
|
| 138 |
N |
A |
-1.2869 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.1760 |
|
| 141 |
P |
A |
-1.6826 |
|
| 142 |
R |
A |
-2.9867 |
|
| 143 |
E |
A |
-3.1996 |
|
| 144 |
A |
A |
-2.3109 |
|
| 145 |
K |
A |
-2.5271 |
|
| 146 |
V |
A |
-1.2273 |
|
| 147 |
Q |
A |
-1.0293 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.6358 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.6370 |
|
| 152 |
N |
A |
-1.4301 |
|
| 153 |
A |
A |
-0.2143 |
|
| 154 |
L |
A |
0.6677 |
|
| 155 |
Q |
A |
-0.2925 |
|
| 156 |
S |
A |
-0.4645 |
|
| 157 |
G |
A |
-1.0280 |
|
| 158 |
N |
A |
-1.0037 |
|
| 159 |
S |
A |
-1.4282 |
|
| 160 |
Q |
A |
-2.2172 |
|
| 161 |
E |
A |
-2.1416 |
|
| 162 |
S |
A |
-1.2207 |
|
| 163 |
V |
A |
-0.6910 |
|
| 164 |
T |
A |
-1.1833 |
|
| 165 |
E |
A |
-2.3131 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.4909 |
|
| 168 |
S |
A |
-2.5128 |
|
| 169 |
K |
A |
-2.8281 |
|
| 170 |
D |
A |
-2.1061 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.0149 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.3984 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5541 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.5349 |
|
| 181 |
L |
A |
-0.7875 |
|
| 182 |
S |
A |
-1.1293 |
|
| 183 |
K |
A |
-2.0818 |
|
| 184 |
A |
A |
-1.9961 |
|
| 185 |
D |
A |
-2.8249 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.7494 |
|
| 188 |
K |
A |
-3.7288 |
|
| 189 |
H |
A |
-3.1739 |
|
| 190 |
K |
A |
-3.1876 |
|
| 191 |
V |
A |
-1.4312 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-1.1058 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.3186 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.7763 |
|
| 200 |
G |
A |
-0.4755 |
|
| 201 |
L |
A |
-0.2516 |
|
| 202 |
S |
A |
-0.4533 |
|
| 203 |
S |
A |
-0.4354 |
|
| 204 |
P |
A |
-0.6565 |
|
| 205 |
V |
A |
-0.0666 |
|
| 206 |
T |
A |
-0.4155 |
|
| 207 |
K |
A |
-0.3583 |
|
| 208 |
S |
A |
-0.3794 |
|
| 209 |
F |
A |
-0.6943 |
|
| 210 |
N |
A |
-1.9620 |
|
| 211 |
R |
A |
-2.4099 |
|
| 212 |
G |
A |
-1.2962 |
|