Project name: 5icx:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7841
• Maximal score value: 2.5251
• Average score: -0.5518
• Total score value: -121.3996

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4163
2	V	B	-0.7406
3	Q	B	-1.5291
4	L	B	0.0000
5	K	B	-2.0923
6	Q	B	0.0000
7	S	B	-0.8486
8	G	B	-1.1795
9	P	B	-0.4828
10	G	B	-0.5356
11	L	B	-0.0037
12	V	B	-0.7976
13	Q	B	-1.7021
14	P	B	-1.5676
15	S	B	-1.6195
16	Q	B	-2.0280
17	S	B	-1.7524
18	L	B	0.0000
19	S	B	-0.7109
20	I	B	0.0000
21	T	B	-0.5518
22	C	B	0.0000
23	T	B	-1.1391
24	V	B	0.0000
25	S	B	-1.1959
26	G	B	-0.9415
27	F	B	-0.5199
28	S	B	-0.9407
29	L	B	0.0000
30	T	B	-1.0175
31	N	B	-0.9419
32	Y	B	0.3122
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.2230
40	S	B	0.0000
41	P	B	-1.0723
42	G	B	-1.6187
43	K	B	-1.9903
44	G	B	-0.6089
45	L	B	0.8140
46	E	B	0.0000
47	W	B	0.4671
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.6647
53	S	B	-0.7562
54	G	B	-1.1726
55	G	B	-1.6013
56	N	B	-1.9745
57	T	B	-1.5365
58	D	B	-1.5600
59	Y	B	-0.7166
60	N	B	-0.6718
61	T	B	-0.5465
62	P	B	-0.4770
63	F	B	0.0000
64	T	B	-0.6254
65	S	B	-0.6705
66	R	B	-1.1557
67	L	B	0.0000
68	S	B	-1.1836
69	I	B	0.0000
70	N	B	-1.8169
71	K	B	-1.6057
72	D	B	-1.9918
73	N	B	-2.5743
74	S	B	-1.8795
75	K	B	-2.4987
76	S	B	-1.7770
77	Q	B	-1.6367
78	V	B	0.0000
79	F	B	-0.3939
80	F	B	0.0000
81	K	B	-1.6676
82	M	B	0.0000
83	N	B	-2.0733
84	S	B	-1.6293
85	L	B	0.0000
86	Q	B	-2.0647
87	S	B	-1.5082
88	N	B	-2.0273
89	D	B	0.0000
90	T	B	-0.6321
91	A	B	0.0000
92	I	B	0.5199
93	Y	B	0.0000
94	Y	B	-0.0452
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.1773
100	T	B	0.9917
101	Y	B	1.7874
102	Y	B	1.4722
103	D	B	0.1296
104	Y	B	0.1014
105	E	B	-1.0733
106	F	B	0.0701
107	A	B	0.5065
108	Y	B	0.5076
109	W	B	0.2022
110	G	B	0.0000
111	Q	B	-1.4244
112	G	B	-0.5745
113	T	B	0.0000
114	L	B	0.4032
115	V	B	0.0000
116	T	B	-0.2735
117	V	B	0.0000
118	S	B	-0.7122
119	A	B	-0.3928
120	A	B	-0.3004
121	S	B	-0.4885
122	T	B	-0.6774
123	K	B	-1.1691
124	G	B	-1.3843
125	P	B	0.0000
126	S	B	-0.1221
127	V	B	0.0000
128	F	B	0.8579
129	P	B	0.0426
130	L	B	0.1742
131	A	B	-1.0653
132	P	B	0.0000
133	S	B	-1.4057
134	S	B	-1.3594
135	K	B	-1.8979
136	S	B	-1.0310
137	T	B	-0.9997
138	S	B	-0.9585
139	G	B	-0.8558
140	G	B	-0.9219
141	T	B	-0.6650
142	A	B	0.0000
143	A	B	-0.2067
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.6843
148	V	B	0.0000
149	K	B	-0.2362
150	D	B	-0.6101
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.3182
155	P	B	-0.4828
156	V	B	-0.5741
157	T	B	-0.5220
158	V	B	-0.1657
159	S	B	-0.4437
160	W	B	0.0000
161	N	B	-0.8250
162	S	B	-0.6934
163	G	B	-0.5829
164	A	B	-0.2534
165	L	B	-0.0381
166	T	B	-0.3049
167	S	B	-0.3735
168	G	B	-0.4603
169	V	B	0.0018
170	H	B	-0.4429
171	T	B	0.1253
172	F	B	0.7782
173	P	B	0.4697
174	A	B	1.2485
175	V	B	2.5251
176	L	B	2.2036
177	Q	B	0.7019
178	S	B	0.0929
179	S	B	-0.1998
180	G	B	0.2697
181	L	B	0.3387
182	Y	B	0.9157
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.5964
186	S	B	0.0000
187	V	B	0.4677
188	V	B	0.0000
189	T	B	-0.2235
190	V	B	0.0000
191	P	B	-0.6324
192	S	B	-0.6885
193	S	B	-0.5862
194	S	B	-0.6045
195	L	B	-0.7476
196	G	B	-0.9112
197	T	B	-0.6751
198	Q	B	-1.1103
199	T	B	-1.0776
200	Y	B	0.0000
201	I	B	-1.3822
202	C	B	0.0000
203	N	B	-1.4681
204	V	B	0.0000
205	N	B	-1.7859
206	H	B	0.0000
207	K	B	-2.7841
208	P	B	-1.5432
209	S	B	-1.7641
210	N	B	-2.5253
211	T	B	-2.0042
212	K	B	-2.6464
213	V	B	-1.7320
214	D	B	-2.6119
215	K	B	-2.1491
216	R	B	-2.5775
217	V	B	0.0000
218	E	B	-2.7077
219	P	B	-1.8343
220	K	B	-2.1937