Project name: 5vsh:B
Status: done
submitted: 2019-03-21 13:07:26, status changed: 2019-03-21 13:18:13
Settings
|
Chain sequence(s)
|
B: DIQMTQSPSSLSASVGDRVTITCKASQDVSIGVAWYQRKPGDAPKLLIYSASYRYTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYYIYPYTFGQGTKVEIKRTVAAPSVFIFPPSKEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6805
-
Maximal score value
-
2.461
-
Average score
-
-0.7147
-
Total score value
-
-152.2257
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
B |
-1.8072 |
|
| 2 |
I |
B |
0.0000 |
|
| 3 |
Q |
B |
-1.9637 |
|
| 4 |
M |
B |
0.0000 |
|
| 5 |
T |
B |
-1.2775 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.7042 |
|
| 8 |
P |
B |
-0.4385 |
|
| 9 |
S |
B |
-0.7705 |
|
| 10 |
S |
B |
-0.7157 |
|
| 11 |
L |
B |
-0.5207 |
|
| 12 |
S |
B |
-0.8235 |
|
| 13 |
A |
B |
-1.0151 |
|
| 14 |
S |
B |
-0.8771 |
|
| 15 |
V |
B |
-0.0628 |
|
| 16 |
G |
B |
-0.8830 |
|
| 17 |
D |
B |
-1.9198 |
|
| 18 |
R |
B |
-2.3974 |
|
| 19 |
V |
B |
0.0000 |
|
| 20 |
T |
B |
-0.6215 |
|
| 21 |
I |
B |
0.0000 |
|
| 22 |
T |
B |
-0.9141 |
|
| 23 |
C |
B |
0.0000 |
|
| 24 |
K |
B |
-2.9597 |
|
| 25 |
A |
B |
0.0000 |
|
| 26 |
S |
B |
-2.3054 |
|
| 27 |
Q |
B |
-2.7872 |
|
| 28 |
D |
B |
-2.7147 |
|
| 29 |
V |
B |
0.0000 |
|
| 30 |
S |
B |
-0.5627 |
|
| 31 |
I |
B |
0.7129 |
|
| 32 |
G |
B |
0.0000 |
|
| 33 |
V |
B |
0.0000 |
|
| 34 |
A |
B |
0.0000 |
|
| 35 |
W |
B |
0.0000 |
|
| 36 |
Y |
B |
0.0621 |
|
| 37 |
Q |
B |
0.0000 |
|
| 38 |
R |
B |
-1.6830 |
|
| 39 |
K |
B |
-2.1455 |
|
| 40 |
P |
B |
-1.6542 |
|
| 41 |
G |
B |
-1.6056 |
|
| 42 |
D |
B |
-2.5418 |
|
| 43 |
A |
B |
-1.4935 |
|
| 44 |
P |
B |
-1.3877 |
|
| 45 |
K |
B |
-1.3266 |
|
| 46 |
L |
B |
-0.0440 |
|
| 47 |
L |
B |
0.0000 |
|
| 48 |
I |
B |
0.0000 |
|
| 49 |
Y |
B |
1.3328 |
|
| 50 |
S |
B |
0.9305 |
|
| 51 |
A |
B |
0.0000 |
|
| 52 |
S |
B |
0.4648 |
|
| 53 |
Y |
B |
1.2434 |
|
| 54 |
R |
B |
0.1387 |
|
| 55 |
Y |
B |
0.6808 |
|
| 56 |
T |
B |
0.1195 |
|
| 57 |
G |
B |
-0.3601 |
|
| 58 |
V |
B |
-0.2773 |
|
| 59 |
P |
B |
-0.3718 |
|
| 60 |
S |
B |
-0.6286 |
|
| 61 |
R |
B |
-0.8049 |
|
| 62 |
F |
B |
0.0000 |
|
| 63 |
S |
B |
-0.2447 |
|
| 64 |
G |
B |
0.0000 |
|
| 65 |
S |
B |
-0.3701 |
|
| 66 |
G |
B |
-0.8490 |
|
| 67 |
S |
B |
-0.9449 |
|
| 68 |
G |
B |
-1.7077 |
|
| 69 |
T |
B |
-2.3687 |
|
| 70 |
D |
B |
-2.8580 |
|
| 71 |
F |
B |
0.0000 |
|
| 72 |
T |
B |
-0.8412 |
|
| 73 |
L |
B |
0.0000 |
|
| 74 |
T |
B |
-0.6179 |
|
| 75 |
I |
B |
0.0000 |
|
| 76 |
S |
B |
-1.5042 |
|
| 77 |
S |
B |
-1.2396 |
|
| 78 |
L |
B |
0.0000 |
|
| 79 |
Q |
B |
-0.8605 |
|
| 80 |
P |
B |
-1.6498 |
|
| 81 |
E |
B |
-1.8941 |
|
| 82 |
D |
B |
0.0000 |
|
| 83 |
F |
B |
0.0000 |
|
| 84 |
A |
B |
0.0000 |
|
| 85 |
T |
B |
0.0000 |
|
| 86 |
Y |
B |
0.0000 |
|
| 87 |
Y |
B |
0.0882 |
|
| 88 |
C |
B |
0.0000 |
|
| 89 |
Q |
B |
0.0000 |
|
| 90 |
Q |
B |
0.0000 |
|
| 91 |
Y |
B |
2.1799 |
|
| 92 |
Y |
B |
2.4610 |
|
| 93 |
I |
B |
2.2743 |
|
| 94 |
Y |
B |
2.0481 |
|
| 95 |
P |
B |
1.3252 |
|
| 96 |
Y |
B |
1.9636 |
|
| 97 |
T |
B |
1.0258 |
|
| 98 |
F |
B |
1.4420 |
|
| 99 |
G |
B |
0.0000 |
|
| 100 |
Q |
B |
-1.0424 |
|
| 101 |
G |
B |
0.0000 |
|
| 102 |
T |
B |
0.0000 |
|
| 103 |
K |
B |
-1.2773 |
|
| 104 |
V |
B |
0.0000 |
|
| 105 |
E |
B |
-1.4076 |
|
| 106 |
I |
B |
0.0000 |
|
| 107 |
K |
B |
-1.2517 |
|
| 108 |
R |
B |
-0.7922 |
|
| 109 |
T |
B |
-0.0351 |
|
| 110 |
V |
B |
0.3840 |
|
| 111 |
A |
B |
0.0488 |
|
| 112 |
A |
B |
-0.2283 |
|
| 113 |
P |
B |
0.0000 |
|
| 114 |
S |
B |
-0.1402 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
F |
B |
1.2295 |
|
| 117 |
I |
B |
1.2202 |
|
| 118 |
F |
B |
1.4468 |
|
| 119 |
P |
B |
-0.1782 |
|
| 120 |
P |
B |
0.0000 |
|
| 121 |
S |
B |
-1.7043 |
|
| 122 |
K |
B |
-3.0625 |
|
| 123 |
E |
B |
-3.2640 |
|
| 124 |
Q |
B |
-2.4138 |
|
| 125 |
L |
B |
-2.4892 |
|
| 126 |
K |
B |
-2.9201 |
|
| 127 |
S |
B |
-1.8986 |
|
| 128 |
G |
B |
-1.3882 |
|
| 129 |
T |
B |
-1.0374 |
|
| 130 |
A |
B |
0.0000 |
|
| 131 |
S |
B |
0.0280 |
|
| 132 |
V |
B |
0.0000 |
|
| 133 |
V |
B |
0.6857 |
|
| 134 |
C |
B |
0.0000 |
|
| 135 |
L |
B |
0.5068 |
|
| 136 |
L |
B |
0.0000 |
|
| 137 |
N |
B |
-0.5617 |
|
| 138 |
N |
B |
-1.2652 |
|
| 139 |
F |
B |
0.0000 |
|
| 140 |
Y |
B |
0.0000 |
|
| 141 |
P |
B |
-1.6350 |
|
| 142 |
R |
B |
-2.6643 |
|
| 143 |
E |
B |
-3.1362 |
|
| 144 |
A |
B |
-2.2658 |
|
| 145 |
K |
B |
-2.3831 |
|
| 146 |
V |
B |
-1.2014 |
|
| 147 |
Q |
B |
-0.8552 |
|
| 148 |
W |
B |
0.0000 |
|
| 149 |
K |
B |
-0.7320 |
|
| 150 |
V |
B |
0.0000 |
|
| 151 |
D |
B |
-2.0649 |
|
| 152 |
N |
B |
-1.6797 |
|
| 153 |
A |
B |
-0.4044 |
|
| 154 |
L |
B |
0.5123 |
|
| 155 |
Q |
B |
-0.2219 |
|
| 156 |
S |
B |
-0.4757 |
|
| 157 |
G |
B |
-0.9798 |
|
| 158 |
N |
B |
-0.9311 |
|
| 159 |
S |
B |
-1.4398 |
|
| 160 |
Q |
B |
-2.2920 |
|
| 161 |
E |
B |
-2.5166 |
|
| 162 |
S |
B |
-1.3342 |
|
| 163 |
V |
B |
-0.7722 |
|
| 164 |
T |
B |
-1.2058 |
|
| 165 |
E |
B |
-2.3142 |
|
| 166 |
Q |
B |
0.0000 |
|
| 167 |
D |
B |
-2.4142 |
|
| 168 |
S |
B |
-2.4200 |
|
| 169 |
K |
B |
-2.7897 |
|
| 170 |
D |
B |
-2.2764 |
|
| 171 |
S |
B |
0.0000 |
|
| 172 |
T |
B |
0.0000 |
|
| 173 |
Y |
B |
0.0000 |
|
| 174 |
S |
B |
-0.9515 |
|
| 175 |
L |
B |
0.0000 |
|
| 176 |
S |
B |
-0.4848 |
|
| 177 |
S |
B |
0.0000 |
|
| 178 |
T |
B |
-0.6847 |
|
| 179 |
L |
B |
0.0000 |
|
| 180 |
T |
B |
-0.5204 |
|
| 181 |
L |
B |
-0.7351 |
|
| 182 |
S |
B |
-1.1606 |
|
| 183 |
K |
B |
-2.3464 |
|
| 184 |
A |
B |
-2.0276 |
|
| 185 |
D |
B |
-2.5434 |
|
| 186 |
Y |
B |
0.0000 |
|
| 187 |
E |
B |
-3.6805 |
|
| 188 |
K |
B |
-3.6594 |
|
| 189 |
H |
B |
-3.0629 |
|
| 190 |
K |
B |
-3.0868 |
|
| 191 |
V |
B |
-1.4039 |
|
| 192 |
Y |
B |
0.0000 |
|
| 193 |
A |
B |
0.0000 |
|
| 194 |
C |
B |
0.0000 |
|
| 195 |
E |
B |
-1.0022 |
|
| 196 |
V |
B |
0.0000 |
|
| 197 |
T |
B |
-1.2422 |
|
| 198 |
H |
B |
0.0000 |
|
| 199 |
Q |
B |
-1.5714 |
|
| 200 |
G |
B |
-0.4377 |
|
| 201 |
L |
B |
-0.2583 |
|
| 202 |
S |
B |
-0.4836 |
|
| 203 |
S |
B |
-0.4467 |
|
| 204 |
P |
B |
-0.5834 |
|
| 205 |
V |
B |
-0.0685 |
|
| 206 |
T |
B |
-0.3831 |
|
| 207 |
K |
B |
-0.3741 |
|
| 208 |
S |
B |
-0.3410 |
|
| 209 |
F |
B |
-0.7608 |
|
| 210 |
N |
B |
-1.8863 |
|
| 211 |
R |
B |
-2.7207 |
|
| 212 |
G |
B |
-2.2704 |
|
| 213 |
E |
B |
-2.5224 |
|