Project name: f3379a67b78145c
Status: done
submitted: 2018-12-16 14:05:13, status changed: 2018-12-16 14:15:31
Settings
|
Chain sequence(s)
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A: AKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
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-3.2603
-
Maximal score value
-
1.6431
-
Average score
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-0.7431
-
Total score value
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-125.5845
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
A |
A |
-0.1951 |
|
| 3 |
K |
A |
-1.3260 |
|
| 4 |
F |
A |
0.0978 |
|
| 5 |
V |
A |
0.9139 |
|
| 6 |
I |
A |
0.1860 |
|
| 7 |
R |
A |
-0.1239 |
|
| 8 |
P |
A |
-0.3708 |
|
| 9 |
A |
A |
-0.2398 |
|
| 10 |
T |
A |
0.0255 |
|
| 11 |
A |
A |
-0.0809 |
|
| 12 |
A |
A |
0.1261 |
|
| 13 |
D |
A |
0.0000 |
|
| 14 |
C |
A |
0.0000 |
|
| 15 |
S |
A |
-0.9730 |
|
| 16 |
D |
A |
-0.7378 |
|
| 17 |
I |
A |
0.0000 |
|
| 18 |
L |
A |
0.0000 |
|
| 19 |
R |
A |
-1.1493 |
|
| 20 |
L |
A |
0.0000 |
|
| 21 |
I |
A |
-0.7445 |
|
| 22 |
K |
A |
-1.7030 |
|
| 23 |
E |
A |
-2.0667 |
|
| 24 |
L |
A |
-1.0124 |
|
| 25 |
A |
A |
-2.0448 |
|
| 26 |
K |
A |
-2.5013 |
|
| 27 |
Y |
A |
-0.6137 |
|
| 28 |
E |
A |
-0.9121 |
|
| 29 |
Y |
A |
0.5063 |
|
| 30 |
M |
A |
-0.2515 |
|
| 31 |
E |
A |
-2.5206 |
|
| 32 |
E |
A |
-2.8562 |
|
| 33 |
Q |
A |
-2.0414 |
|
| 34 |
V |
A |
-0.0901 |
|
| 35 |
I |
A |
1.6089 |
|
| 36 |
L |
A |
0.3438 |
|
| 37 |
T |
A |
-1.1192 |
|
| 38 |
E |
A |
-3.0200 |
|
| 39 |
K |
A |
-3.2603 |
|
| 40 |
D |
A |
-2.5527 |
|
| 41 |
L |
A |
0.0000 |
|
| 42 |
L |
A |
-1.8199 |
|
| 43 |
E |
A |
-3.1604 |
|
| 44 |
D |
A |
-2.3068 |
|
| 45 |
G |
A |
-1.0278 |
|
| 46 |
F |
A |
-0.7641 |
|
| 47 |
G |
A |
-1.8207 |
|
| 48 |
E |
A |
-2.5640 |
|
| 49 |
H |
A |
-1.8309 |
|
| 50 |
P |
A |
-0.6021 |
|
| 51 |
F |
A |
0.9885 |
|
| 52 |
Y |
A |
0.0000 |
|
| 53 |
H |
A |
-0.0397 |
|
| 54 |
C |
A |
0.0000 |
|
| 55 |
L |
A |
0.0000 |
|
| 56 |
V |
A |
0.0000 |
|
| 57 |
A |
A |
0.0000 |
|
| 58 |
E |
A |
-0.2888 |
|
| 59 |
V |
A |
0.0000 |
|
| 60 |
P |
A |
-1.6818 |
|
| 61 |
K |
A |
-2.7656 |
|
| 62 |
E |
A |
-3.0147 |
|
| 63 |
H |
A |
-2.0934 |
|
| 64 |
W |
A |
-1.5759 |
|
| 65 |
T |
A |
0.0000 |
|
| 66 |
P |
A |
-1.2839 |
|
| 67 |
E |
A |
-2.1674 |
|
| 68 |
G |
A |
-1.9283 |
|
| 69 |
H |
A |
-1.3301 |
|
| 70 |
S |
A |
-1.1164 |
|
| 71 |
I |
A |
0.0000 |
|
| 72 |
V |
A |
0.0000 |
|
| 73 |
G |
A |
0.0000 |
|
| 74 |
F |
A |
0.0000 |
|
| 75 |
A |
A |
0.0000 |
|
| 76 |
M |
A |
-0.4428 |
|
| 77 |
Y |
A |
0.0000 |
|
| 78 |
Y |
A |
0.8264 |
|
| 79 |
F |
A |
1.2977 |
|
| 80 |
T |
A |
0.7856 |
|
| 81 |
Y |
A |
1.2658 |
|
| 82 |
D |
A |
0.5728 |
|
| 83 |
P |
A |
0.6499 |
|
| 84 |
W |
A |
1.6214 |
|
| 85 |
I |
A |
1.6407 |
|
| 86 |
G |
A |
0.4129 |
|
| 87 |
K |
A |
-0.1049 |
|
| 88 |
L |
A |
0.0000 |
|
| 89 |
L |
A |
0.0000 |
|
| 90 |
Y |
A |
0.4173 |
|
| 91 |
L |
A |
0.0000 |
|
| 92 |
E |
A |
-1.2524 |
|
| 93 |
D |
A |
-0.7411 |
|
| 94 |
F |
A |
-0.1018 |
|
| 95 |
F |
A |
0.0000 |
|
| 96 |
V |
A |
0.0000 |
|
| 97 |
M |
A |
-0.7671 |
|
| 98 |
S |
A |
-1.4891 |
|
| 99 |
D |
A |
-1.9572 |
|
| 100 |
Y |
A |
-1.0330 |
|
| 101 |
R |
A |
-1.2576 |
|
| 102 |
G |
A |
-0.3731 |
|
| 103 |
F |
A |
0.8468 |
|
| 104 |
G |
A |
0.1487 |
|
| 105 |
I |
A |
0.0000 |
|
| 106 |
G |
A |
-0.5316 |
|
| 107 |
S |
A |
-0.9128 |
|
| 108 |
E |
A |
-1.1903 |
|
| 109 |
I |
A |
0.0000 |
|
| 110 |
L |
A |
-1.1994 |
|
| 111 |
K |
A |
-2.3731 |
|
| 112 |
N |
A |
-1.6539 |
|
| 113 |
L |
A |
0.0000 |
|
| 114 |
S |
A |
-1.1337 |
|
| 115 |
Q |
A |
-1.6976 |
|
| 116 |
V |
A |
0.0000 |
|
| 117 |
A |
A |
-0.8349 |
|
| 118 |
M |
A |
-0.7904 |
|
| 119 |
R |
A |
-2.0401 |
|
| 120 |
C |
A |
-1.4209 |
|
| 121 |
R |
A |
-2.2155 |
|
| 122 |
C |
A |
-0.6850 |
|
| 123 |
S |
A |
-0.3917 |
|
| 124 |
S |
A |
-0.2067 |
|
| 125 |
M |
A |
0.2166 |
|
| 126 |
H |
A |
0.2437 |
|
| 127 |
F |
A |
0.6519 |
|
| 128 |
L |
A |
1.5582 |
|
| 129 |
V |
A |
0.8052 |
|
| 130 |
A |
A |
-0.1135 |
|
| 131 |
E |
A |
-1.4278 |
|
| 132 |
W |
A |
-0.2385 |
|
| 133 |
N |
A |
-1.0391 |
|
| 134 |
E |
A |
-1.8029 |
|
| 135 |
P |
A |
-0.7277 |
|
| 136 |
S |
A |
-0.5758 |
|
| 137 |
I |
A |
-0.7974 |
|
| 138 |
N |
A |
-1.3941 |
|
| 139 |
F |
A |
-0.5910 |
|
| 140 |
Y |
A |
-1.5164 |
|
| 141 |
K |
A |
-2.7013 |
|
| 142 |
R |
A |
-3.0874 |
|
| 143 |
R |
A |
-3.1210 |
|
| 144 |
G |
A |
-2.2696 |
|
| 145 |
A |
A |
-1.6862 |
|
| 146 |
S |
A |
-1.7076 |
|
| 147 |
D |
A |
-1.7257 |
|
| 148 |
L |
A |
-1.3209 |
|
| 149 |
S |
A |
-1.4616 |
|
| 150 |
S |
A |
-2.0116 |
|
| 151 |
E |
A |
-2.9029 |
|
| 152 |
E |
A |
-2.8628 |
|
| 153 |
G |
A |
-1.8666 |
|
| 154 |
W |
A |
-0.2497 |
|
| 155 |
R |
A |
-0.3333 |
|
| 156 |
L |
A |
1.6431 |
|
| 157 |
F |
A |
1.5010 |
|
| 158 |
K |
A |
-0.7021 |
|
| 159 |
I |
A |
-0.7275 |
|
| 160 |
D |
A |
-2.2507 |
|
| 161 |
K |
A |
-2.4308 |
|
| 162 |
E |
A |
-1.9510 |
|
| 163 |
Y |
A |
-0.1082 |
|
| 164 |
L |
A |
0.4897 |
|
| 165 |
L |
A |
0.4549 |
|
| 166 |
K |
A |
-0.6334 |
|
| 167 |
M |
A |
0.0110 |
|
| 168 |
A |
A |
0.4153 |
|
| 169 |
T |
A |
-0.4894 |
|
| 170 |
E |
A |
-1.5449 |
|