Project name: Model1

Chain sequence(s)	A: MAALHTLWMGLVLLGVLGVLQTRAQAQVSRQPNFQQDKFLGRWFTSGLASNSSWFREKKNALSMCISVVAPSAEGGLNLTTTFLRKDQCETRTLLLRPAETPGCYSYTSPHWGSTHDVWVVATDYEEYALLYTAGTKSPGQDFHMATLYSRTQTPRAEVKEKFSTFAKTRGFTEDAIVFLPKTERCMEEHR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4081
• Maximal score value: 3.1014
• Average score: -0.7368
• Total score value: -140.7193

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	1.8868
2	A	A	1.4367
3	A	A	1.8234
4	L	A	0.0000
5	H	A	0.6851
6	T	A	0.7420
7	L	A	1.7573
8	W	A	0.0000
9	M	A	1.3498
10	G	A	1.6693
11	L	A	2.2590
12	V	A	2.1098
13	L	A	3.1014
14	L	A	3.0880
15	G	A	0.0000
16	V	A	0.0000
17	L	A	0.0154
18	G	A	0.0000
19	V	A	1.0902
20	L	A	1.7280
21	Q	A	-0.5374
22	T	A	-0.5481
23	R	A	-1.7548
24	A	A	-1.0932
25	Q	A	-1.2527
26	A	A	-0.7144
27	Q	A	-1.4818
28	V	A	0.0000
29	S	A	-0.2472
30	R	A	-0.5443
31	Q	A	-1.1030
32	P	A	-1.0083
33	N	A	-1.7453
34	F	A	-1.7739
35	Q	A	-2.5569
36	Q	A	-2.1746
37	D	A	-2.9198
38	K	A	-3.2607
39	F	A	0.0000
40	L	A	-1.3273
41	G	A	-1.1748
42	R	A	-1.0275
43	W	A	0.0000
44	F	A	-0.6668
45	T	A	0.0000
46	S	A	0.0000
47	G	A	0.0000
48	L	A	0.5450
49	A	A	0.0000
50	S	A	0.0000
51	N	A	-1.6545
52	S	A	-1.0024
53	S	A	-1.0527
54	W	A	-0.4409
55	F	A	-1.5646
56	R	A	-3.3542
57	E	A	-3.0992
58	K	A	-2.5092
59	K	A	-2.1913
60	N	A	-2.3820
61	A	A	-1.3300
62	L	A	-0.8115
63	S	A	0.0000
64	M	A	0.0000
65	C	A	-0.0072
66	I	A	0.0000
67	S	A	0.0000
68	V	A	0.2193
69	V	A	0.0349
70	A	A	-0.3928
71	P	A	-0.8526
72	S	A	-0.8939
73	A	A	-1.0949
74	E	A	-2.1646
75	G	A	-1.6026
76	G	A	0.0000
77	L	A	0.0000
78	N	A	-0.2019
79	L	A	0.0000
80	T	A	-0.3261
81	T	A	0.0000
82	T	A	-0.4487
83	F	A	-0.6002
84	L	A	0.0000
85	R	A	-2.4357
86	K	A	-3.3178
87	D	A	-3.4081
88	Q	A	-2.5696
89	C	A	-2.1321
90	E	A	-1.2307
91	T	A	-1.2602
92	R	A	-1.8080
93	T	A	-0.6108
94	L	A	0.1706
95	L	A	0.6935
96	L	A	0.0000
97	R	A	-1.1613
98	P	A	-0.9054
99	A	A	-1.1929
100	E	A	-1.8666
101	T	A	0.0000
102	P	A	-1.2116
103	G	A	0.0000
104	C	A	0.0000
105	Y	A	0.0000
106	S	A	-0.5829
107	Y	A	-0.0361
108	T	A	-0.4133
109	S	A	-0.4367
110	P	A	-0.5722
111	H	A	-0.7197
112	W	A	0.2330
113	G	A	-0.6200
114	S	A	-0.8302
115	T	A	-0.8710
116	H	A	-0.9471
117	D	A	-0.8731
118	V	A	0.0000
119	W	A	0.0000
120	V	A	0.0000
121	V	A	0.0000
122	A	A	-0.5744
123	T	A	0.0000
124	D	A	-1.8675
125	Y	A	-2.2371
126	E	A	-2.7578
127	E	A	-2.0687
128	Y	A	0.0000
129	A	A	-0.5703
130	L	A	0.0000
131	L	A	0.2409
132	Y	A	0.0000
133	T	A	-0.1356
134	A	A	-0.6051
135	G	A	0.0000
136	T	A	-1.6263
137	K	A	-1.6257
138	S	A	-1.0804
139	P	A	-1.1034
140	G	A	-1.4647
141	Q	A	-2.0779
142	D	A	-1.9269
143	F	A	-0.7887
144	H	A	0.0000
145	M	A	0.0551
146	A	A	0.0000
147	T	A	0.3351
148	L	A	0.0000
149	Y	A	0.0000
150	S	A	0.0000
151	R	A	-1.5705
152	T	A	-1.3134
153	Q	A	-1.7254
154	T	A	-1.2187
155	P	A	-0.9837
156	R	A	-1.4027
157	A	A	-1.4309
158	E	A	-1.9693
159	V	A	0.0000
160	K	A	-1.7095
161	E	A	-2.8720
162	K	A	-2.4270
163	F	A	0.0000
164	S	A	0.0000
165	T	A	-1.7310
166	F	A	0.0000
167	A	A	0.0000
168	K	A	-1.5494
169	T	A	-1.1122
170	R	A	-1.1878
171	G	A	-1.0862
172	F	A	-1.0496
173	T	A	-1.5889
174	E	A	-2.1292
175	D	A	-2.2007
176	A	A	0.0000
177	I	A	0.0000
178	V	A	0.0000
179	F	A	1.0921
180	L	A	0.0000
181	P	A	-0.7836
182	K	A	-1.8516
183	T	A	-1.7159
184	E	A	-2.2372
185	R	A	-2.0949
186	C	A	-1.6812
187	M	A	-0.6191
188	E	A	-2.7466
189	E	A	-3.4079
190	H	A	-3.1393
191	R	A	-3.1312