Project name: 5vh4:H

Chain sequence(s)	H: EVKLEESGGGLVQQPGGSMKLSCVASGFIFSNHWMNWVRQSPEKGLEWVAEIRSKSINSATHYAESVKGRFTISRDDSKSAVYLQMTDLRTTEDTGVYYCSRNYYGSTYDYWGQGTTLTVSSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSSLSSVVTVPSSSLGTQQTYICNVNHKPSNTKVDKKVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9694
• Maximal score value: 2.4539
• Average score: -0.6207
• Total score value: -137.799

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1946
2	V	H	-1.3292
3	K	H	-2.2379
4	L	H	0.0000
5	E	H	-1.7760
6	E	H	0.0000
7	S	H	-0.9654
8	G	H	-0.9820
9	G	H	-0.8922
10	G	H	-0.5473
11	L	H	-0.3046
12	V	H	0.0000
13	Q	H	-1.8596
14	P	H	-1.9867
15	G	H	-1.9548
16	G	H	-1.4496
17	S	H	-1.5144
18	M	H	-1.3947
19	K	H	-2.1652
20	L	H	0.0000
21	S	H	-0.6943
22	C	H	0.0000
23	V	H	-0.0714
24	A	H	0.0000
25	S	H	-0.9018
26	G	H	-0.8636
27	F	H	0.3419
28	I	H	1.5496
29	F	H	0.0000
30	S	H	-0.7758
31	N	H	-0.9402
32	H	H	-0.2140
33	W	H	-0.2627
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6298
40	S	H	-1.5231
41	P	H	-1.5901
42	E	H	-2.9694
43	K	H	-2.7783
44	G	H	-1.1488
45	L	H	0.5499
46	E	H	0.1036
47	W	H	0.5448
48	V	H	0.0000
49	A	H	0.0000
50	E	H	0.0000
51	I	H	0.0000
52	R	H	-1.0332
53	S	H	0.0000
54	K	H	-2.2647
55	S	H	-1.0338
56	I	H	-0.0846
57	N	H	-1.3669
58	S	H	-1.2845
59	A	H	-0.6868
60	T	H	-0.4985
61	H	H	-0.8891
62	Y	H	-1.1159
63	A	H	-1.3916
64	E	H	-2.5385
65	S	H	-1.5904
66	V	H	0.0000
67	K	H	-2.6771
68	G	H	-1.8371
69	R	H	-1.5530
70	F	H	0.0000
71	T	H	-0.9673
72	I	H	0.0000
73	S	H	-0.4643
74	R	H	-0.9118
75	D	H	-1.3051
76	D	H	-1.2980
77	S	H	-1.3595
78	K	H	-1.8582
79	S	H	-0.5710
80	A	H	0.0000
81	V	H	0.0000
82	Y	H	-0.4902
83	L	H	0.0000
84	Q	H	-1.5854
85	M	H	0.0000
86	T	H	-1.6617
87	D	H	-2.2951
88	L	H	0.0000
89	R	H	-2.6434
90	T	H	-1.8979
91	E	H	-2.7438
92	D	H	0.0000
93	T	H	-0.9523
94	G	H	-0.7074
95	V	H	0.1078
96	Y	H	0.0000
97	Y	H	0.0154
98	C	H	0.0000
99	S	H	0.0000
100	R	H	0.0000
101	N	H	0.0000
102	Y	H	1.1216
103	Y	H	0.7135
104	G	H	0.0754
105	S	H	0.0370
106	T	H	0.2236
107	Y	H	0.5588
108	D	H	0.1827
109	Y	H	0.5869
110	W	H	0.0242
111	G	H	-0.9129
112	Q	H	-1.5987
113	G	H	0.0000
114	T	H	-0.5697
115	T	H	-0.3202
116	L	H	0.0000
117	T	H	-0.6599
118	V	H	0.0000
119	S	H	-1.0438
120	S	H	-0.7679
121	A	H	-0.4896
122	S	H	-0.6018
123	T	H	-0.6516
124	K	H	-1.2284
125	G	H	-1.4645
126	P	H	-0.5744
127	S	H	-0.1032
128	V	H	0.0000
129	F	H	0.9125
130	P	H	0.1540
131	L	H	0.3422
132	A	H	-0.8432
133	P	H	0.0000
134	S	H	-1.4325
135	S	H	-1.2771
136	K	H	-1.9400
137	S	H	-1.1102
138	T	H	-1.1022
139	S	H	-0.9765
140	G	H	-0.8913
141	G	H	-0.9134
142	T	H	-0.6633
143	A	H	0.0000
144	A	H	-0.1886
145	L	H	0.0000
146	G	H	0.0000
147	C	H	0.0000
148	L	H	0.7154
149	V	H	0.0000
150	K	H	-0.2588
151	D	H	-0.6354
152	Y	H	0.0000
153	F	H	0.0000
154	P	H	0.0000
155	E	H	-0.5351
156	P	H	-0.7367
157	V	H	-0.6076
158	T	H	-0.5104
159	V	H	-0.3591
160	S	H	-0.3547
161	W	H	0.0000
162	N	H	-0.7177
163	S	H	-0.6543
164	G	H	-0.5073
165	A	H	-0.2494
166	L	H	-0.0293
167	T	H	-0.3034
168	S	H	-0.3702
169	G	H	-0.4711
170	V	H	0.0249
171	H	H	-0.3614
172	T	H	0.2063
173	F	H	0.9429
174	P	H	0.7037
175	A	H	1.2336
176	V	H	2.4539
177	L	H	2.0129
178	Q	H	0.6480
179	S	H	0.0600
180	S	H	-0.2559
181	G	H	0.1398
182	L	H	0.2327
183	Y	H	0.7678
184	S	H	0.0000
185	L	H	0.0000
186	S	H	0.6497
187	S	H	0.0000
188	V	H	0.4439
189	V	H	0.0000
190	T	H	-0.2500
191	V	H	0.0000
192	P	H	-0.6420
193	S	H	-0.6163
194	S	H	-0.5546
195	S	H	-0.5996
196	L	H	-0.7515
197	G	H	-1.0934
198	T	H	-0.7163
199	Q	H	-1.2397
200	T	H	-1.0673
201	Y	H	0.0000
202	I	H	-1.2178
203	C	H	0.0000
204	N	H	-1.4360
205	V	H	0.0000
206	N	H	-1.7603
207	H	H	0.0000
208	K	H	-2.7259
209	P	H	-1.6276
210	S	H	-1.8299
211	N	H	-2.5237
212	T	H	-2.1882
213	K	H	-2.6272
214	V	H	-1.6271
215	D	H	-2.5266
216	K	H	-2.1186
217	K	H	-2.2981
218	V	H	0.0000
219	E	H	-2.8468
220	P	H	-1.9403
221	K	H	-2.3255
222	S	H	-1.3113