Project name: 4ojf:H
Status: done
submitted: 2019-03-21 14:47:41, status changed: 2019-03-21 14:56:40
Settings
|
Chain sequence(s)
|
H: VQLLESGGGLVQPGGSLRLSCAASGFTFSNYGMSWVRQAPGKGLEWVASIRSGGGRTYYSDNVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCVRYDHYSGSSDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPQPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8406
-
Maximal score value
-
2.4201
-
Average score
-
-0.5746
-
Total score value
-
-125.8358
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 2 |
V |
H |
1.3523 |
|
| 3 |
Q |
H |
0.2054 |
|
| 4 |
L |
H |
0.0000 |
|
| 5 |
L |
H |
0.5613 |
|
| 6 |
E |
H |
0.0000 |
|
| 7 |
S |
H |
-0.5397 |
|
| 8 |
G |
H |
-0.9557 |
|
| 9 |
G |
H |
-0.7572 |
|
| 10 |
G |
H |
-0.5825 |
|
| 11 |
L |
H |
-0.1767 |
|
| 12 |
V |
H |
0.0000 |
|
| 13 |
Q |
H |
-1.6060 |
|
| 14 |
P |
H |
-1.6470 |
|
| 15 |
G |
H |
-1.3137 |
|
| 16 |
G |
H |
0.0000 |
|
| 17 |
S |
H |
-1.2520 |
|
| 18 |
L |
H |
-1.1618 |
|
| 19 |
R |
H |
-2.0736 |
|
| 20 |
L |
H |
0.0000 |
|
| 21 |
S |
H |
-0.4801 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
A |
H |
-0.2416 |
|
| 24 |
A |
H |
0.0000 |
|
| 25 |
S |
H |
0.0085 |
|
| 26 |
G |
H |
0.1133 |
|
| 27 |
F |
H |
0.0800 |
|
| 28 |
T |
H |
-0.3973 |
|
| 29 |
F |
H |
0.0000 |
|
| 30 |
S |
H |
-1.3334 |
|
| 31 |
N |
H |
-1.6792 |
|
| 32 |
Y |
H |
-0.9917 |
|
| 33 |
G |
H |
0.0000 |
|
| 34 |
M |
H |
0.0000 |
|
| 35 |
S |
H |
0.1136 |
|
| 36 |
W |
H |
0.0000 |
|
| 37 |
V |
H |
0.6626 |
|
| 38 |
R |
H |
0.0000 |
|
| 39 |
Q |
H |
-0.3853 |
|
| 40 |
A |
H |
-1.0428 |
|
| 41 |
P |
H |
-1.0993 |
|
| 42 |
G |
H |
-1.5671 |
|
| 43 |
K |
H |
-2.0634 |
|
| 44 |
G |
H |
-0.9122 |
|
| 45 |
L |
H |
0.7555 |
|
| 46 |
E |
H |
0.0723 |
|
| 47 |
W |
H |
0.3142 |
|
| 48 |
V |
H |
0.0000 |
|
| 49 |
A |
H |
0.0000 |
|
| 50 |
S |
H |
-0.3836 |
|
| 51 |
I |
H |
0.0000 |
|
| 52 |
R |
H |
-2.8253 |
|
| 52A |
S |
H |
-2.0365 |
|
| 53 |
G |
H |
-1.9303 |
|
| 54 |
G |
H |
-1.8414 |
|
| 55 |
G |
H |
-2.2446 |
|
| 56 |
R |
H |
-2.7671 |
|
| 57 |
T |
H |
-1.2356 |
|
| 58 |
Y |
H |
-0.2801 |
|
| 59 |
Y |
H |
-0.6662 |
|
| 60 |
S |
H |
-1.5114 |
|
| 61 |
D |
H |
-2.8282 |
|
| 62 |
N |
H |
-2.8406 |
|
| 63 |
V |
H |
0.0000 |
|
| 64 |
K |
H |
-2.7919 |
|
| 65 |
G |
H |
-1.9200 |
|
| 66 |
R |
H |
-1.6534 |
|
| 67 |
F |
H |
0.0000 |
|
| 68 |
T |
H |
-0.7209 |
|
| 69 |
I |
H |
0.0000 |
|
| 70 |
S |
H |
-0.8735 |
|
| 71 |
R |
H |
-1.2482 |
|
| 72 |
D |
H |
-1.4949 |
|
| 73 |
N |
H |
-1.8357 |
|
| 74 |
A |
H |
-1.4088 |
|
| 75 |
K |
H |
-2.2814 |
|
| 76 |
N |
H |
-1.7080 |
|
| 77 |
S |
H |
0.0000 |
|
| 78 |
L |
H |
0.0000 |
|
| 79 |
Y |
H |
-0.4612 |
|
| 80 |
L |
H |
0.0000 |
|
| 81 |
Q |
H |
-1.1314 |
|
| 82 |
M |
H |
0.0000 |
|
| 82A |
N |
H |
-1.4602 |
|
| 82B |
S |
H |
-1.2217 |
|
| 82C |
L |
H |
0.0000 |
|
| 83 |
R |
H |
-2.2123 |
|
| 84 |
A |
H |
-1.6775 |
|
| 85 |
E |
H |
-2.3339 |
|
| 86 |
D |
H |
0.0000 |
|
| 87 |
T |
H |
-0.7671 |
|
| 88 |
A |
H |
0.0000 |
|
| 89 |
L |
H |
0.3101 |
|
| 90 |
Y |
H |
0.0000 |
|
| 91 |
Y |
H |
0.5299 |
|
| 92 |
C |
H |
0.0000 |
|
| 93 |
V |
H |
0.0000 |
|
| 94 |
R |
H |
0.0000 |
|
| 95 |
Y |
H |
-0.1586 |
|
| 96 |
D |
H |
0.0000 |
|
| 97 |
H |
H |
-0.5871 |
|
| 98 |
Y |
H |
0.7025 |
|
| 99 |
S |
H |
-0.1695 |
|
| 100 |
G |
H |
-0.5946 |
|
| 100A |
S |
H |
-0.4676 |
|
| 100B |
S |
H |
-0.3634 |
|
| 101 |
D |
H |
-0.3405 |
|
| 102 |
Y |
H |
0.9285 |
|
| 103 |
W |
H |
0.7375 |
|
| 104 |
G |
H |
0.1857 |
|
| 105 |
Q |
H |
-0.8664 |
|
| 106 |
G |
H |
0.0000 |
|
| 107 |
T |
H |
-0.1234 |
|
| 108 |
L |
H |
-0.0473 |
|
| 109 |
V |
H |
0.0000 |
|
| 110 |
T |
H |
-0.4859 |
|
| 111 |
V |
H |
0.0000 |
|
| 112 |
S |
H |
-0.9577 |
|
| 113 |
S |
H |
-0.6589 |
|
| 114 |
A |
H |
-0.4632 |
|
| 115 |
S |
H |
-0.6056 |
|
| 116 |
T |
H |
-0.6457 |
|
| 117 |
K |
H |
-1.2364 |
|
| 118 |
G |
H |
-1.4394 |
|
| 119 |
P |
H |
-0.5504 |
|
| 120 |
S |
H |
-0.0814 |
|
| 121 |
V |
H |
0.0000 |
|
| 122 |
F |
H |
1.0937 |
|
| 123 |
P |
H |
0.1943 |
|
| 124 |
L |
H |
0.4101 |
|
| 125 |
A |
H |
-0.6160 |
|
| 126 |
P |
H |
-0.9995 |
|
| 127 |
S |
H |
-1.1337 |
|
| 128 |
S |
H |
-1.7521 |
|
| 129 |
K |
H |
-2.0923 |
|
| 130 |
S |
H |
-1.5305 |
|
| 131 |
T |
H |
-0.9706 |
|
| 132 |
S |
H |
-0.7910 |
|
| 133 |
G |
H |
-0.7944 |
|
| 134 |
G |
H |
-0.7718 |
|
| 135 |
T |
H |
-0.5658 |
|
| 136 |
A |
H |
-0.5276 |
|
| 137 |
A |
H |
0.1003 |
|
| 138 |
L |
H |
0.0000 |
|
| 139 |
G |
H |
0.0000 |
|
| 140 |
C |
H |
0.0000 |
|
| 141 |
L |
H |
0.7661 |
|
| 142 |
V |
H |
0.0000 |
|
| 143 |
K |
H |
-0.2120 |
|
| 144 |
D |
H |
-0.3923 |
|
| 145 |
Y |
H |
0.0000 |
|
| 146 |
F |
H |
0.0000 |
|
| 147 |
P |
H |
0.0000 |
|
| 148 |
Q |
H |
-0.3093 |
|
| 149 |
P |
H |
-0.5477 |
|
| 150 |
V |
H |
-0.5249 |
|
| 151 |
T |
H |
-0.4510 |
|
| 152 |
V |
H |
-0.1391 |
|
| 153 |
S |
H |
-0.4394 |
|
| 154 |
W |
H |
0.0000 |
|
| 155 |
N |
H |
-0.7762 |
|
| 156 |
S |
H |
-0.6950 |
|
| 157 |
G |
H |
-0.5293 |
|
| 158 |
A |
H |
-0.2471 |
|
| 159 |
L |
H |
-0.0343 |
|
| 160 |
T |
H |
-0.2979 |
|
| 161 |
S |
H |
-0.3689 |
|
| 162 |
G |
H |
-0.4582 |
|
| 163 |
V |
H |
0.0273 |
|
| 164 |
H |
H |
-0.4342 |
|
| 165 |
T |
H |
0.1919 |
|
| 166 |
F |
H |
0.9429 |
|
| 167 |
P |
H |
0.7270 |
|
| 168 |
A |
H |
1.2893 |
|
| 169 |
V |
H |
2.4201 |
|
| 170 |
L |
H |
2.0376 |
|
| 171 |
Q |
H |
0.6462 |
|
| 172 |
S |
H |
0.0687 |
|
| 173 |
S |
H |
-0.2132 |
|
| 174 |
G |
H |
0.2027 |
|
| 175 |
L |
H |
0.2996 |
|
| 176 |
Y |
H |
0.8762 |
|
| 177 |
S |
H |
0.0000 |
|
| 178 |
L |
H |
0.0000 |
|
| 179 |
S |
H |
0.6728 |
|
| 180 |
S |
H |
0.0000 |
|
| 181 |
V |
H |
0.4626 |
|
| 182 |
V |
H |
0.0000 |
|
| 183 |
T |
H |
-0.2158 |
|
| 184 |
V |
H |
0.0000 |
|
| 185 |
P |
H |
-0.4229 |
|
| 186 |
S |
H |
-0.6670 |
|
| 187 |
S |
H |
-0.5172 |
|
| 188 |
S |
H |
-0.5776 |
|
| 189 |
L |
H |
-0.6043 |
|
| 190 |
G |
H |
-0.9453 |
|
| 191 |
T |
H |
-0.7835 |
|
| 192 |
Q |
H |
-1.2060 |
|
| 193 |
T |
H |
-1.0968 |
|
| 194 |
Y |
H |
0.0000 |
|
| 195 |
I |
H |
-1.3347 |
|
| 196 |
C |
H |
0.0000 |
|
| 197 |
N |
H |
-1.4142 |
|
| 198 |
V |
H |
0.0000 |
|
| 199 |
N |
H |
-1.7324 |
|
| 200 |
H |
H |
0.0000 |
|
| 201 |
K |
H |
-2.7133 |
|
| 202 |
P |
H |
-1.5473 |
|
| 203 |
S |
H |
-1.8111 |
|
| 204 |
N |
H |
-2.5020 |
|
| 205 |
T |
H |
-2.0521 |
|
| 206 |
K |
H |
-2.5944 |
|
| 207 |
V |
H |
-1.4645 |
|
| 208 |
D |
H |
-2.4586 |
|
| 209 |
K |
H |
-1.8037 |
|
| 210 |
K |
H |
-2.2033 |
|
| 211 |
V |
H |
0.0000 |
|
| 212 |
E |
H |
-2.6093 |
|
| 213 |
P |
H |
-2.0587 |
|
| 214 |
K |
H |
-2.2519 |
|